Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis

Human and Experimental Toxicology

Volumn 33, Issue 10, 2014, Pages 1051-1065

  Kolli, V K ^a   Natarajan, K ^a   Isaac, B ^a   Selvakumar, D ^a   Abraham, P ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Methotrexate; mitochondrial dysfunction; rat; respiratory chain defects; small intestinal injury

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; METHOTREXATE; SUCCINATE DEHYDROGENASE (UBIQUINONE); MULTIENZYME COMPLEX; PEROXYNITROUS ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENTERITIS; ENZYME SYNTHESIS; INTESTINE CELL; INTESTINE INJURY; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; WEIGHT REDUCTION; ANIMAL; CELL SURVIVAL; CHEMICALLY INDUCED; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON TRANSPORT; METABOLISM; PATHOLOGY; SMALL INTESTINE; TIME; ULTRASTRUCTURE; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS; RODENTIA;

ANIMALS; CELL SURVIVAL; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ENTERITIS; ENTEROCYTES; INTESTINE, SMALL; MALE; METHOTREXATE; MITOCHONDRIA; MITOCHONDRIAL DISEASES; PEROXYNITROUS ACID; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TIME FACTORS; WEIGHT LOSS;

EID: 84921029767     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327113515503     Document Type: Article

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