Methotrexate-induced nitrosative stress may play a critical role in small intestinal damage in the rat

Archives of Toxicology

Volumn 82, Issue 10, 2008, Pages 763-770

  Kolli, Viswa Kalyan ^a   Abraham, Premila ^a   Rabi, Suganthy ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Methotrexate; Nitrosative stress; Nitrotyrosine; Rat; Small intestine

Indexed keywords

3 NITROTYROSINE; METHOTREXATE; MYELOPEROXIDASE; NITRITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DISEASE SEVERITY; DUODENUM; ENZYME ACTIVITY; EXPERIMENTAL MODEL; GASTROINTESTINAL TOXICITY; HISTOPATHOLOGY; ILEUM; INTESTINE INJURY; INTESTINE VILLUS; JEJUNUM; MALE; NEUTROPHIL CHEMOTAXIS; NITROSATIVE STRESS; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE LEVEL;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BODY WEIGHT; DUODENUM; ILEUM; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAPERITONEAL; INTESTINE, SMALL; JEJUNUM; MALE; METHOTREXATE; NEUTROPHIL INFILTRATION; NEUTROPHILS; NITRITES; OXIDATIVE STRESS; PEROXIDASE; RATS; RATS, WISTAR; REACTIVE NITROGEN SPECIES; TIME FACTORS; TYROSINE;

RATTUS;

EID: 55049133247     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-008-0287-9     Document Type: Article

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