Selective insulin resistance in hepatocyte senescence

Experimental Cell Research

Volumn 331, Issue 1, 2015, Pages 38-45

  Aravinthan, Aloysious ^a   Challis, Benjamin ^a   Shannon, Nicholas ^b   Hoare, Matthew ^a,b   Heaney, Judith ^a,c   Alexander, Graeme J M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^c INSTITUTE OF HEPATOLOGY   (United Kingdom)

Author keywords

Chronic liver disease; Hepatocyte senescence; Selective insulin resistance

Indexed keywords

CELL PROTEIN; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 4; INSULIN; PROTEIN AS160; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; BIOLOGICAL MARKER; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; SLC2A2 PROTEIN, HUMAN; SLC2A4 PROTEIN, HUMAN;

ARTICLE; CHRONIC LIVER DISEASE; CONTROLLED STUDY; DISEASE ASSESSMENT; DISEASE MARKER; ENZYME PHOSPHORYLATION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN METABOLISM; INSULIN RESISTANCE; LIVER CELL; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SENESCENCE; SIGNAL TRANSDUCTION; CELL AGING; DRUG EFFECTS; LIVER DISEASES; METABOLISM; PATHOLOGY; PHOSPHORYLATION; WESTERN BLOTTING;

BIOMARKERS; BLOTTING, WESTERN; CELL AGING; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE TRANSPORTER TYPE 2; GLUCOSE TRANSPORTER TYPE 4; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; LIVER DISEASES; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 84921027226     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.09.025     Document Type: Article

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