Premature telomere shortening and impaired regenerative response in hepatocytes of individuals with NAFLD

Liver International

Volumn 26, Issue 1, 2006, Pages 23-31

  Nakajima, Tomoki ^a   Moriguchi, Michihisa ^a   Katagishi, Tatsuo ^a   Sekoguchi, Satoru ^a   Nishikawa, Taichirou ^a   Takashima, Hidetaka ^a   Kimura, Hiroyuki ^a   Minami, Masahito ^a   Itoh, Yoshito ^a   Kagawa, Keizo ^b   Tani, Yoichi ^c   Okanoue, Takeshi ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Fukuchiyama City Hospital   (Japan)

^c DakoCytomation ^*  (Japan)

Author keywords

Nonalcoholic fatty liver disease; Quantitative fluorescence in situ hybridization; Replicative senescence; Telomere

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALANINE AMINOTRANSFERASE; INSULIN; KI 67 ANTIGEN; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ARTICLE; BODY MASS; CELL REGENERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HEPATITIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; LIVER CELL; LIVER NECROSIS; LIVER REGENERATION; MALE; NONALCOHOLIC FATTY LIVER; TELOMERE;

ADULT; AGED; BIOPSY, NEEDLE; CASE-CONTROL STUDIES; CELLS, CULTURED; CHROMOSOMAL INSTABILITY; DISEASE PROGRESSION; FATTY LIVER; FEMALE; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; INSULIN RESISTANCE; LIVER CIRRHOSIS; LIVER REGENERATION; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; PROBABILITY; PROGNOSIS; REFERENCE VALUES; RISK FACTORS; SENSITIVITY AND SPECIFICITY; STATISTICS, NONPARAMETRIC; TELOMERE;

EID: 33645958898     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2005.01178.x     Document Type: Article

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