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Volumn 125, Issue 2, 2015, Pages 358-369

Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 3; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; GATA2 PROTEIN, MOUSE; INTERFERON REGULATORY FACTOR; TRANSCRIPTION FACTOR;

EID: 84920973718     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-02-557983     Document Type: Article
Times cited : (52)

References (50)
  • 1
    • 84876913029 scopus 로고    scopus 로고
    • Protective and pathological roles of mast cells and basophils
    • Voehringer D. Protective and pathological roles of mast cells and basophils. Nat Rev Immunol. 2013;13(5):362-375.
    • (2013) Nat Rev Immunol , vol.13 , Issue.5 , pp. 362-375
    • Voehringer, D.1
  • 3
    • 77957020655 scopus 로고    scopus 로고
    • Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths
    • Ohnmacht C, Schwartz C, Panzer M, Schiedewitz I, Naumann R, Voehringer D. Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths. Immunity. 2010;33(3):364-374.
    • (2010) Immunity. , vol.33 , Issue.3 , pp. 364-374
    • Ohnmacht, C.1    Schwartz, C.2    Panzer, M.3    Schiedewitz, I.4    Naumann, R.5    Voehringer, D.6
  • 4
    • 84856830988 scopus 로고    scopus 로고
    • Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness
    • Sawaguchi M, Tanaka S, Nakatani Y, et al. Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness. J Immunol. 2012;188(4):1809-1818.
    • (2012) J Immunol , vol.188 , Issue.4 , pp. 1809-1818
    • Sawaguchi, M.1    Tanaka, S.2    Nakatani, Y.3
  • 5
    • 84887448189 scopus 로고    scopus 로고
    • The skin is an important bulwark of acquired immunity against intestinal helminths
    • Obata-Ninomiya K, Ishiwata K, Tsutsui H, et al. The skin is an important bulwark of acquired immunity against intestinal helminths. J Exp Med. 2013;210(12):2583-2595.
    • (2013) J Exp Med , vol.210 , Issue.12 , pp. 2583-2595
    • Obata-Ninomiya, K.1    Ishiwata, K.2    Tsutsui, H.3
  • 6
    • 24744453077 scopus 로고    scopus 로고
    • Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance
    • Hida S, Tadachi M, Saito T, Taki S. Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Blood. 2005;106(6):2011-2017.
    • (2005) Blood , vol.106 , Issue.6 , pp. 2011-2017
    • Hida, S.1    Tadachi, M.2    Saito, T.3    Taki, S.4
  • 7
    • 33947597895 scopus 로고    scopus 로고
    • Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils
    • Oh K, Shen T, Le Gros G, Min B. Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils. Blood. 2007;109(7):2921-2927.
    • (2007) Blood , vol.109 , Issue.7 , pp. 2921-2927
    • Oh, K.1    Shen, T.2    Le Gros, G.3    Min, B.4
  • 8
    • 84877737842 scopus 로고    scopus 로고
    • Basophils are required for the induction of Th2 immunity to haptens and peptide antigens
    • Otsuka A, Nakajima S, Kubo M, et al. Basophils are required for the induction of Th2 immunity to haptens and peptide antigens. Nat Commun. 2013;4:1739.
    • (2013) Nat Commun , vol.4 , pp. 1739
    • Otsuka, A.1    Nakajima, S.2    Kubo, M.3
  • 9
    • 41549112786 scopus 로고    scopus 로고
    • Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis
    • Tsujimura Y, Obata K, Mukai K, et al. Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity. 2008;28(4):581-589.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 581-589
    • Tsujimura, Y.1    Obata, K.2    Mukai, K.3
  • 10
    • 70349756896 scopus 로고    scopus 로고
    • Mast cellmediated antigen presentation regulates CD81 T cell effector functions
    • Stelekati E, Bahri R, D'Orlando O, et al. Mast cellmediated antigen presentation regulates CD81 T cell effector functions. Immunity. 2009;31(4):665-676.
    • (2009) Immunity , vol.31 , Issue.4 , pp. 665-676
    • Stelekati, E.1    Bahri, R.2    D'Orlando, O.3
  • 11
    • 84880255551 scopus 로고    scopus 로고
    • Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection
    • Guermonprez P, Helft J, Claser C, et al. Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection. Nat Med. 2013;19(6):730-738.
    • (2013) Nat Med , vol.19 , Issue.6 , pp. 730-738
    • Guermonprez, P.1    Helft, J.2    Claser, C.3
  • 12
    • 34250214880 scopus 로고    scopus 로고
    • Myeloid lineage commitment from the hematopoietic stem cell
    • Iwasaki H, Akashi K. Myeloid lineage commitment from the hematopoietic stem cell. Immunity. 2007;26(6):726-740.
    • (2007) Immunity , vol.26 , Issue.6 , pp. 726-740
    • Iwasaki, H.1    Akashi, K.2
  • 13
    • 39349096526 scopus 로고    scopus 로고
    • Hematopoiesis: An evolving paradigm for stem cell biology
    • Orkin SH, Zon LI. Hematopoiesis: an evolving paradigm for stem cell biology. Cell. 2008;132(4):631-644.
    • (2008) Cell , vol.132 , Issue.4 , pp. 631-644
    • Orkin, S.H.1    Zon, L.I.2
  • 14
    • 77949895560 scopus 로고    scopus 로고
    • Distinguishing mast cell and granulocyte differentiation at the single-cell level
    • Franco CB, Chen CC, Drukker M, Weissman IL, Galli SJ. Distinguishing mast cell and granulocyte differentiation at the single-cell level. Cell Stem Cell. 2010;6(4):361-368.
    • (2010) Cell Stem Cell , vol.6 , Issue.4 , pp. 361-368
    • Franco, C.B.1    Chen, C.C.2    Drukker, M.3    Weissman, I.L.4    Galli, S.J.5
  • 15
    • 84863584416 scopus 로고    scopus 로고
    • Critical role of P1-Runx1 in mouse basophil development
    • Mukai K, BenBarak MJ, Tachibana M, et al. Critical role of P1-Runx1 in mouse basophil development. Blood. 2012;120(1):76-85.
    • (2012) Blood , vol.120 , Issue.1 , pp. 76-85
    • Mukai, K.1    BenBarak, M.J.2    Tachibana, M.3
  • 16
    • 84880728627 scopus 로고    scopus 로고
    • Antagonistic regulation by the transcription factors C/EBPa and MITF specifies basophil and mast cell fates
    • Qi X, Hong J, Chaves L, et al. Antagonistic regulation by the transcription factors C/EBPa and MITF specifies basophil and mast cell fates. Immunity. 2013;39(1):97-110.
    • (2013) Immunity , vol.39 , Issue.1 , pp. 97-110
    • Qi, X.1    Hong, J.2    Chaves, L.3
  • 17
    • 29144472957 scopus 로고    scopus 로고
    • Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis
    • Arinobu Y, Iwasaki H, Gurish MF, et al. Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. Proc Natl Acad Sci USA. 2005;102(50):18105-18110.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.50 , pp. 18105-18110
    • Arinobu, Y.1    Iwasaki, H.2    Gurish, M.F.3
  • 19
    • 76249095169 scopus 로고    scopus 로고
    • Development of monocytes, macrophages, and dendritic cells
    • Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Development of monocytes, macrophages, and dendritic cells. Science. 2010;327(5966):656-661.
    • (2010) Science , vol.327 , Issue.5966 , pp. 656-661
    • Geissmann, F.1    Manz, M.G.2    Jung, S.3    Sieweke, M.H.4    Merad, M.5    Ley, K.6
  • 20
    • 84887436574 scopus 로고    scopus 로고
    • GATA-1 regulates the generation and function of basophils
    • Nei Y, Obata-Ninomiya K, Tsutsui H, et al. GATA-1 regulates the generation and function of basophils. Proc Natl Acad Sci USA. 2013;110(46):18620-18625.
    • (2013) Proc Natl Acad Sci USA. , vol.110 , Issue.46 , pp. 18620-18625
    • Nei, Y.1    Obata-Ninomiya, K.2    Tsutsui, H.3
  • 21
    • 7344251174 scopus 로고    scopus 로고
    • Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells
    • Harigae H, Takahashi S, Suwabe N, et al. Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells. Genes Cells. 1998;3(1):39-50.
    • (1998) Genes Cells , vol.3 , Issue.1 , pp. 39-50
    • Harigae, H.1    Takahashi, S.2    Suwabe, N.3
  • 22
    • 33751071630 scopus 로고    scopus 로고
    • The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages
    • Iwasaki H, Mizuno S, Arinobu Y, et al. The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev. 2006;20(21):3010-3021.
    • (2006) Genes Dev , vol.20 , Issue.21 , pp. 3010-3021
    • Iwasaki, H.1    Mizuno, S.2    Arinobu, Y.3
  • 23
    • 64849086165 scopus 로고    scopus 로고
    • IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen
    • Ohmori K, Luo Y, Jia Y, et al. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. J Immunol. 2009;182(5):2835-2841.
    • (2009) J Immunol , vol.182 , Issue.5 , pp. 2835-2841
    • Ohmori, K.1    Luo, Y.2    Jia, Y.3
  • 24
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • Tamura T, Yanai H, Savitsky D, Taniguchi T. The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol. 2008;26:535-584.
    • (2008) Annu Rev Immunol , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 25
    • 84878605147 scopus 로고    scopus 로고
    • PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment
    • Schönheit J, Kuhl C, Gebhardt ML, et al. PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment. Cell Reports. 2013;3(5):1617-1628.
    • (2013) Cell Reports , vol.3 , Issue.5 , pp. 1617-1628
    • Schönheit, J.1    Kuhl, C.2    Gebhardt, M.L.3
  • 26
    • 84905977761 scopus 로고    scopus 로고
    • A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation
    • Wang H, Yan M, Sun J, et al. A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation. J Immunol. 2014;193(4):1766-1777.
    • (2014) J Immunol , vol.193 , Issue.4 , pp. 1766-1777
    • Wang, H.1    Yan, M.2    Sun, J.3
  • 27
    • 84920965751 scopus 로고    scopus 로고
    • IRF8 inhibits C/EBPa activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils
    • Kurotaki D, Yamamoto M, Nishiyama A, et al. IRF8 inhibits C/EBPa activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils. Nat Commun. 2014;5:4978.
    • (2014) Nat Commun , vol.5 , pp. 4978
    • Kurotaki, D.1    Yamamoto, M.2    Nishiyama, A.3
  • 28
    • 0033680746 scopus 로고    scopus 로고
    • ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages
    • Tamura T, Nagamura-Inoue T, Shmeltzer Z, Kuwata T, Ozato K. ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages. Immunity. 2000;13(2):155-165.
    • (2000) Immunity , vol.13 , Issue.2 , pp. 155-165
    • Tamura, T.1    Nagamura-Inoue, T.2    Shmeltzer, Z.3    Kuwata, T.4    Ozato, K.5
  • 29
    • 0037220671 scopus 로고    scopus 로고
    • Essential role for ICSBP in the in vivo development of murine CD8a1 dendritic cells
    • Aliberti J, Schulz O, Pennington DJ, et al. Essential role for ICSBP in the in vivo development of murine CD8a1 dendritic cells. Blood. 2003;101(1):305-310.
    • (2003) Blood , vol.101 , Issue.1 , pp. 305-310
    • Aliberti, J.1    Schulz, O.2    Pennington, D.J.3
  • 30
    • 0037011021 scopus 로고    scopus 로고
    • ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8a1 dendritic cells
    • Schiavoni G, Mattei F, Sestili P, et al. ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8a1 dendritic cells. J Exp Med. 2002;196(11):1415-1425.
    • (2002) J Exp Med , vol.196 , Issue.11 , pp. 1415-1425
    • Schiavoni, G.1    Mattei, F.2    Sestili, P.3
  • 31
    • 84876493933 scopus 로고    scopus 로고
    • Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation
    • Kurotaki D, Osato N, Nishiyama A, et al. Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood. 2013;121(10):1839-1849.
    • (2013) Blood , vol.121 , Issue.10 , pp. 1839-1849
    • Kurotaki, D.1    Osato, N.2    Nishiyama, A.3
  • 32
    • 58149311492 scopus 로고    scopus 로고
    • IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development
    • Milanovic M, Terszowski G, Struck D, Liesenfeld O, Carstanjen D. IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development. J Immunol. 2008;181(7):5045-5053.
    • (2008) J Immunol , vol.181 , Issue.7 , pp. 5045-5053
    • Milanovic, M.1    Terszowski, G.2    Struck, D.3    Liesenfeld, O.4    Carstanjen, D.5
  • 33
    • 16044369709 scopus 로고    scopus 로고
    • Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
    • Holtschke T, Löhler J, Kanno Y, et al. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell. 1996;87(2):307-317.
    • (1996) Cell , vol.87 , Issue.2 , pp. 307-317
    • Holtschke, T.1    Löhler, J.2    Kanno, Y.3
  • 34
    • 84864147310 scopus 로고    scopus 로고
    • The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells
    • Kanaya T, Hase K, Takahashi D, et al. The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat Immunol. 2012;13(8):729-736.
    • (2012) Nat Immunol , vol.13 , Issue.8 , pp. 729-736
    • Kanaya, T.1    Hase, K.2    Takahashi, D.3
  • 35
    • 0019954883 scopus 로고
    • Mast cells in spotted mutant mice (W Ph mi)
    • Stevens J, Loutit JF. Mast cells in spotted mutant mice (W Ph mi). Proc R Soc Lond B Biol Sci. 1982;215(1200):405-409.
    • (1982) Proc R Soc Lond B Biol Sci , vol.215 , Issue.1200 , pp. 405-409
    • Stevens, J.1    Loutit, J.F.2
  • 36
    • 84908545176 scopus 로고    scopus 로고
    • Mast cell progenitors: Origin, development and migration to tissues
    • Dahlin JS, Hallgren J. Mast cell progenitors: Origin, development and migration to tissues. Mol Immunol. 2015;63(1):9-17.
    • (2015) Mol Immunol , vol.63 , Issue.1 , pp. 9-17
    • Dahlin, J.S.1    Hallgren, J.2
  • 37
    • 77957947005 scopus 로고    scopus 로고
    • Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis
    • Jo SH, Schatz JH, Acquaviva J, Singh H, Ren R. Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis. Blood. 2010;116(15):2759-2767.
    • (2010) Blood , vol.116 , Issue.15 , pp. 2759-2767
    • Jo, S.H.1    Schatz, J.H.2    Acquaviva, J.3    Singh, H.4    Ren, R.5
  • 38
    • 26444490607 scopus 로고    scopus 로고
    • Partnerregulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages
    • Laricchia-Robbio L, Tamura T, Karpova T, Sprague BL, McNally JG, Ozato K. Partnerregulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages. Proc Natl Acad Sci USA. 2005;102(40):14368-14373.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.40 , pp. 14368-14373
    • Laricchia-Robbio, L.1    Tamura, T.2    Karpova, T.3    Sprague, B.L.4    McNally, J.G.5    Ozato, K.6
  • 39
    • 84894280989 scopus 로고    scopus 로고
    • The transcription factor IRF8 activates integrinmediated TGF-b signaling and promotes neuroinflammation
    • Yoshida Y, Yoshimi R, Yoshii H, et al. The transcription factor IRF8 activates integrinmediated TGF-b signaling and promotes neuroinflammation. Immunity. 2014;40(2):187-198.
    • (2014) Immunity , vol.40 , Issue.2 , pp. 187-198
    • Yoshida, Y.1    Yoshimi, R.2    Yoshii, H.3
  • 40
    • 80053926066 scopus 로고    scopus 로고
    • Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development
    • Yamamoto M, Kato T, Hotta C, et al. Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development. PLoS ONE. 2011;6(10):e25812.
    • (2011) PLoS ONE , vol.6 , Issue.10
    • Yamamoto, M.1    Kato, T.2    Hotta, C.3
  • 41
    • 52649097448 scopus 로고    scopus 로고
    • The Immunological Genome Project: Networks of gene expression in immune cells
    • Immunological Genome Project Consortium.
    • Heng TS, Painter MW; Immunological Genome Project Consortium. The Immunological Genome Project: networks of gene expression in immune cells. Nat Immunol. 2008;9(10):1091-1094.
    • (2008) Nat Immunol , vol.9 , Issue.10 , pp. 1091-1094
    • Heng, T.S.1    Painter, M.W.2
  • 43
    • 0030670801 scopus 로고    scopus 로고
    • Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression
    • Giese NA, Gabriele L, Doherty TM, et al. Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression. J Exp Med. 1997;186(9):1535-1546.
    • (1997) J Exp Med , vol.186 , Issue.9 , pp. 1535-1546
    • Giese, N.A.1    Gabriele, L.2    Doherty, T.M.3
  • 44
    • 0034948713 scopus 로고    scopus 로고
    • Regulation of mast cell survival by IgE
    • Asai K, Kitaura J, Kawakami Y, et al. Regulation of mast cell survival by IgE. Immunity. 2001;14(6):791-800.
    • (2001) Immunity , vol.14 , Issue.6 , pp. 791-800
    • Asai, K.1    Kitaura, J.2    Kawakami, Y.3
  • 45
    • 79960219807 scopus 로고    scopus 로고
    • IRF8 mutations and human dendritic-cell immunodeficiency
    • Hambleton S, Salem S, Bustamante J, et al. IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011;365(2):127-138.
    • (2011) N Engl J Med , vol.365 , Issue.2 , pp. 127-138
    • Hambleton, S.1    Salem, S.2    Bustamante, J.3
  • 46
    • 0041806587 scopus 로고    scopus 로고
    • GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling
    • Grass JA, Boyer ME, Pal S, Wu J, Weiss MJ, Bresnick EH. GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proc Natl Acad Sci USA. 2003;100(15):8811-8816.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.15 , pp. 8811-8816
    • Grass, J.A.1    Boyer, M.E.2    Pal, S.3    Wu, J.4    Weiss, M.J.5    Bresnick, E.H.6
  • 47
    • 41549151507 scopus 로고    scopus 로고
    • The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8
    • Esashi E, Wang YH, Perng O, Qin XF, Liu YJ, Watowich SS. The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8. Immunity. 2008;28(4):509-520.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 509-520
    • Esashi, E.1    Wang, Y.H.2    Perng, O.3    Qin, X.F.4    Liu, Y.J.5    Watowich, S.S.6
  • 48
    • 84879689439 scopus 로고    scopus 로고
    • Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks
    • Murphy TL, Tussiwand R, Murphy KM. Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks. Nat Rev Immunol. 2013;13(7):499-509.
    • (2013) Nat Rev Immunol , vol.13 , Issue.7 , pp. 499-509
    • Murphy, T.L.1    Tussiwand, R.2    Murphy, K.M.3
  • 49
    • 0242549003 scopus 로고    scopus 로고
    • Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
    • McKercher SR, Torbett BE, Anderson KL, et al. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J. 1996;15(20):5647-5658.
    • (1996) EMBO J , vol.15 , Issue.20 , pp. 5647-5658
    • McKercher, S.R.1    Torbett, B.E.2    Anderson, K.L.3
  • 50
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • Scott EW, Simon MC, Anastasi J, Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science. 1994;265(5178):1573-1577.
    • (1994) Science , vol.265 , Issue.5178 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4


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