IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen

Journal of Immunology

Volumn 182, Issue 5, 2009, Pages 2835-2841

  Ohmori, Keitaro ^a,f   Luo, Yuchun ^a   Jia, Yi ^a   Nishida, Jun ^a   Wang, Zhengqi ^b   Bunting, Kevin D ^b   Wang, Demin ^c,d   Huang, Hua ^a,e  

^a DEPARTMENT OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BLOOD RESEARCH INSTITUTE   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

^e UNIVERSITY OF COLORADO   (United States)

^f TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD123 ANTIGEN; INTERLEUKIN 3; INTERLEUKIN 3 RECEPTOR; STAT5 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOPHIL; BONE MARROW; CELL COUNT; CELL DIFFERENTIATION; CELL EXPANSION; CELL LINEAGE; CONTROLLED STUDY; EOSINOPHIL; FETUS; GRANULOCYTE; IN VIVO STUDY; MAST CELL; MONOCYTE; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SPLEEN; STEM CELL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; COLONY FORMING UNIT GM; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GRANULOCYTE PRECURSOR; IMMUNOLOGY; LEUKOCYTE COUNT; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; BASOPHILS; CELL DIFFERENTIATION; CELL LINEAGE; GENE EXPRESSION REGULATION; GRANULOCYTE PRECURSOR CELLS; GRANULOCYTE-MACROPHAGE PROGENITOR CELLS; INTERLEUKIN-3; LEUKOCYTE COUNT; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELOID PROGENITOR CELLS; RECEPTORS, INTERLEUKIN-3; SPLEEN; UP-REGULATION;

EID: 64849086165     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802870     Document Type: Article

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