Mast cell progenitors: Origin, development and migration to tissues

Molecular Immunology

Volumn 63, Issue 1, 2015, Pages 9-17

  Dahlin, Joakim S ^a   Hallgren, Jenny ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Development; Mast cell progenitors; Mast cells; Mouse; Recruitment

Indexed keywords

INTERLEUKIN 9; OVALBUMIN; TRANSCRIPTION FACTOR; VASCULAR CELL ADHESION MOLECULE 1;

BASOPHIL; BONE MARROW; BONE MARROW CELL; CELL DIFFERENTIATION; CELL MATURATION; CELL MIGRATION; CELL MOTILITY; CELL SUSPENSION; CYTOKINE PRODUCTION; DEVELOPMENTAL STAGE; EMBRYONIC STEM CELL; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTESTINE; LUNG; MAST CELL; MAST CELL DEGRANULATION; MOLECULE; NONHUMAN; ONTOGENY; PERITONEUM; PRENATAL PERIOD; REVIEW; SKIN; STEM CELL; STEM CELL MOBILIZATION; TISSUES; ANIMAL; CELL MOTION; CYTOLOGY; HYPERSENSITIVITY; IMMUNOLOGY; INFLAMMATION; MOUSE; RAT; STOMACH;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL MOVEMENT; HUMANS; HYPERSENSITIVITY; INFLAMMATION; LUNG; MAST CELLS; MICE; RATS; STEM CELLS; STOMACH; TRANSCRIPTION FACTORS;

EID: 84908545176     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2014.01.018     Document Type: Review

References (91)

1. Abonia J.P., Austen K.F., Rollins B.J., Joshi S.K., Flavell R.A., Kuziel W.A., Koni P.A., Gurish M.F. Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2. Blood 2005, 105:4308-4313.
2. Abonia J.P., Hallgren J., Jones T., Shi T., Xu Y., Koni P., Flavell R.A., Boyce J.A., Austen K.F., Gurish M.F. Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung. Blood 2006, 108:1588-1594.
3. Akashi K., Traver D., Miyamoto T., Weissman I.L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000, 404:193-197.
4. Ammit A.J., Bekir S.S., Johnson P.R., Hughes J.M., Armour C.L., Black J.L. Mast cell numbers are increased in the smooth muscle of human sensitized isolated bronchi. Am. J. Respir. Crit. Care Med. 1997, 155:1123-1129.
5. Arinobu Y., Iwasaki H., Gurish M.F., Mizuno S., Shigematsu H., Ozawa H., Tenen D.G., Austen K.F., Akashi K. Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:18105-18110.
6. Asai K., Kitaura J., Kawakami Y., Yamagata N., Tsai M., Carbone D.P., Liu F.T., Galli S.J., Kawakami T. Regulation of mast cell survival by IgE. Immunity 2001, 14:791-800.
7. Berlanga O., Emambokus N., Frampton J. GPIIb (CD41) integrin is expressed on mast cells and influences their adhesion properties. Exp. Hematol. 2005, 33:403-412.
8. Brightling C.E., Bradding P., Symon F.A., Holgate S.T., Wardlaw A.J., Pavord I.D. Mast-cell infiltration of airway smooth muscle in asthma. N. Engl. J. Med. 2002, 346:1699-1705.
9. Brown J.K., Knight P.A., Pemberton A.D., Wright S.H., Pate J.A., Thornton E.M., Miller H.R. Expression of integrin-alphaE by mucosal mast cells in the intestinal epithelium and its absence in nematode-infected mice lacking the transforming growth factor-beta1-activating integrin alphavbeta6. Am. J. Pathol. 2004, 165:95-106.
10. Cantor A.B., Iwasaki H., Arinobu Y., Moran T.B., Shigematsu H., Sullivan M.R., Akashi K., Orkin S.H. Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage. J. Exp. Med. 2008, 205:611-624.
11. Chang D.Z., Ma Y., Ji B., Wang H., Deng D., Liu Y., Abbruzzese J.L., Liu Y.J., Logsdon C.D., Hwu P. Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma. Clin. Cancer Res. Off. J. Am. Assoc. Cancer Res. 2011, 17:7015-7023.
12. Chen C.C., Grimbaldeston M.A., Tsai M., Weissman I.L., Galli S.J. Identification of mast cell progenitors in adult mice. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:11408-11413.
13. Collington S.J., Hallgren J., Pease J.E., Jones T.G., Rollins B.J., Westwick J., Austen K.F., Williams T.J., Gurish M.F., Weller C.L. The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo. J. Immunol. 2010, 184:6114-6123.
14. Collmann E., Bohnacker T., Marone R., Dawson J., Rehberg M., Stringer R., Krombach F., Burkhart C., Hirsch E., Hollingworth G.J., Thomas M., Wymann M.P. Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy. J. Allergy Clin. Immunol. 2013, 132:959-968.
15. Crapper R.M., Schrader J.W. Frequency of mast cell precursors in normal tissues determined by an in vitro assay: antigen induces parallel increases in the frequency of P cell precursors and mast cells. J. Immunol. 1983, 131:923-928.
16. Dahlin J.S., Ivarsson M.A., Heyman B., Hallgren J. IgE immune complexes stimulate an increase in lung mast cell progenitors in a mouse model of allergic airway inflammation. PLoS ONE 2011, 6:e20261.
17. Dahlin J.S., Feinstein R., Cui Y., Heyman B., Hallgren J. CD11c+ cells are required for antigen-induced increase of mast cells in the lung. J. Immunol. 2012, 189:3869-3877.
18. Dahlin J.S., Heyman B., Hallgren J. Committed mast cell progenitors in mouse blood differ in maturity between Th1 and Th2 strains. Allergy 2013, 68:1333-1337.
19. Dillon S.B., MacDonald T.T. Limit dilution analysis of mast cell precursor frequency in the gut epithelium of normal and Trichinella spiralis infected mice. Parasite Immunol. 1986, 8:503.
20. Ebi Y., Kasugai T., Seino Y., Onoue H., Kanemoto T., Kitamura Y. Mechanism of mast cell deficiency in mutant mice of mi/mi genotype: an analysis by co-culture of mast cells and fibroblasts. Blood 1990, 75:1247-1251.
21. Franco C.B., Chen C.C., Drukker M., Weissman I.L., Galli S.J. Distinguishing mast cell and granulocyte differentiation at the single-cell level. Cell Stem Cell 2010, 6:361-368.
22. Furuichi K., Rivera J., Triche T., Isersky C. The fate of IgE bound to rat basophilic leukemia cells. IV. Functional association between the receptors for IgE. J. Immunol. 1985, 134:1766-1773.
23. Guiraldelli M.F., Berenstein E.H., Grodzki A.C., Siraganian R.P., Jamur M.C., Oliver C. The low affinity IgG receptor Fc gamma RIIB contributes to the binding of the mast cell specific antibody, mAb BGD6. Mol. Immunol. 2008, 45:2411-2418.
24. Guiraldelli M.F., Franca C.N., de Souza D.A., da Silva E.Z., Toso V.D., Carvalho C.C., Jamur M.C., Oliver C. Rat embryonic mast cells originate in the AGM. PLoS ONE 2013, 8:e57862.
25. Guo N.H., Her G.R., Reinhold V.N., Brennan M.J., Siraganian R.P., Ginsburg V. Monoclonal antibody AA4, which inhibits binding of IgE to high affinity receptors on rat basophilic leukemia cells, binds to novel alpha-galactosyl derivatives of ganglioside GD1b. J. Biol. Chem. 1989, 264:13267-13272.
26. Gurish M.F., Tao H., Abonia J.P., Arya A., Friend D.S., Parker C.M., Austen K.F. Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing. J. Exp. Med. 2001, 194:1243-1252.
27. Guy-Grand D., Dy M., Luffau G., Vassalli P. Gut mucosal mast cells. Origin, traffic, and differentiation. J. Exp. Med. 1984, 160:12-28.
28. Hallgren J., Jones T.G., Abonia J.P., Xing W., Humbles A., Austen K.F., Gurish M.F. Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:20478-20483.
29. Harigae H., Takahashi S., Suwabe N., Ohtsu H., Gu L., Yang Z., Tsai F.Y., Kitamura Y., Engel J.D., Yamamoto M. Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells. Genes Cells 1998, 3:39.
30. Hayashi C., Sonoda T., Nakano T., Nakayama H., Kitamura Y. Mast-cell precursors in the skin of mouse embryos and their deficiency in embryos of Sl/Sld genotype. Dev. Biol. 1985, 109:234-241.
31. Iwasaki H., Mizuno S., Mayfield R., Shigematsu H., Arinobu Y., Seed B., Gurish M.F., Takatsu K., Akashi K. Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J. Exp. Med. 2005, 201:1891-1897.
32. Iwasaki H., Mizuno S., Arinobu Y., Ozawa H., Mori Y., Shigematsu H., Takatsu K., Tenen D.G., Akashi K. The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev. 2006, 20:3010-3021.
33. Jamur M.C., Grodzki A.C., Berenstein E.H., Hamawy M.M., Siraganian R.P., Oliver C. Identification and characterization of undifferentiated mast cells in mouse bone marrow. Blood 2005, 105:4282-4289.
34. Jamur M.C., Moreno A.N., Mello L.F., Souza Junior D.A., Campos M.R., Pastor M.V., Grodzki A.C., Silva D.C., Oliver C. Mast cell repopulation of the peritoneal cavity: contribution of mast cell progenitors versus bone marrow derived committed mast cell precursors. BMC Immunol. 2010, 11:32.
35. Jones T.G., Hallgren J., Humbles A., Burwell T., Finkelman F.D., Alcaide P., Austen K.F., Gurish M.F. Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. J. Immunol. 2009, 183:5251-5260.
36. Jones T.G., Finkelman F.D., Austen K.F., Gurish M.F. T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57BL/6 mice. J. Immunol. 2010, 185:1804-1811.
37. Kakizoe E., Li S.H., Kobayashi Y., Nishikori Y., Dekio S., Okunishi H. Increases in mast cells and chymase in fibroproliferative paws of collagen-induced arthritic mice. Inflamm. Res. Off. J. Eur. Histamine Res. Soc. 1999, 48:318-324.
38. Kalesnikoff J., Huber M., Lam V., Damen J.E., Zhang J., Siraganian R.P., Krystal G. Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival. Immunity 2001, 14:801-811.
39. Kambe N., Kambe M., Kochan J.P., Schwartz L.B. Human skin-derived mast cells can proliferate while retaining their characteristic functional and protease phenotypes. Blood 2001, 97:2045-2052.
40. Kasugai T., Tei H., Okada M., Hirota S., Morimoto M., Yamada M., Nakama A., Arizono N., Kitamura Y. Infection with Nippostrongylus brasiliensis induces invasion of mast cell precursors from peripheral blood to small intestine. Blood 1995, 85:1334.
41. Kempuraj D., Saito H., Kaneko A., Fukagawa K., Nakayama M., Toru H., Tomikawa M., Tachimoto H., Ebisawa M., Akasawa A., Miyagi T., Kimura H., Nakajima T., Tsuji K., Nakahata T. Characterization of mast cell-committed progenitors present in human umbilical cord blood. Blood 1999, 93:3338-3346.
42. Khalil R.M., Luz A., Mailhammer R., Moeller J., Mohamed A.A., Omran S., Dormer P., Hultner L. Schistosoma mansoni infection in mice augments the capacity for interleukin 3 (IL-3) and IL-9 production and concurrently enlarges progenitor pools for mast cells and granulocytes-macrophages. Infect. Immun. 1996, 64:4960-4966.
43. Kirshenbaum A.S., Kessler S.W., Goff J.P., Metcalfe D.D. Demonstration of the origin of human mast cells from CD34+ bone marrow progenitor cells. J. Immunol. 1991, 146:1410.
44. Kirshenbaum A.S., Goff J.P., Semere T., Foster B., Scott L.M., Metcalfe D.D. Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13). Blood 1999, 94:2333-2342.
45. Kitamura Y., Shimada M., Hatanaka K., Miyano Y. Development of mast cells from grafted bone marrow cells in irradiated mice. Nature 1977, 268:442-443.
46. Kitaura J., Kinoshita T., Matsumoto M., Chung S., Kawakami Y., Leitges M., Wu D., Lowell C.A., Kawakami T. IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion. Blood 2005, 105:3222-3229.
47. Knight P.A., Wright S.H., Brown J.K., Huang X., Sheppard D., Miller H.R. Enteric expression of the integrin alpha(v)beta(6) is essential for nematode-induced mucosal mast cell hyperplasia and expression of the granule chymase, mouse mast cell protease-1. Am. J. Pathol. 2002, 161:771-779.
48. Knight P.A., Brown J.K., Wright S.H., Thornton E.M., Pate J.A., Miller H.R. Aberrant mucosal mast cell protease expression in the enteric epithelium of nematode-infected mice lacking the integrin alphavbeta6, a transforming growth factor-beta1 activator. Am. J. Pathol. 2007, 171:1237-1248.
49. Kobayasi T., Asboe-Hansen G. Degranulation and regranulation of human mast cells. An electron microscopic study of the whealing reaction in urticaria pigmentosa. Acta Derm. Venereol. 1969, 49:369-381.
50. Kondo M., Weissman I.L., Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997, 91:661-672.
51. Liu A.Y., Dwyer D.F., Jones T.G., Bankova L.G., Shen S., Katz H.R., Austen K.F., Gurish M.F. Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6. J. Immunol. 2013, 190:1758-1766.
52. Lloyd C.M., Hessel E.M. Functions of T cells in asthma: more than just T(H)2 cells. Nat. Rev. Immunol. 2010, 10:838-848.
53. Metcalf D., Ng A.P., Baldwin T.M., Di Rago L., Mifsud S. Concordant mast cell and basophil production by individual hematopoietic blast colony-forming cells. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:9031-9035.
54. Migliaccio A.R., Rana R.A., Sanchez M., Lorenzini R., Centurione L., Bianchi L., Vannucchi A.M., Migliaccio G., Orkin S.H. GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant. J. Exp. Med. 2003, 197:281-296.
55. Molin D., Edstrom A., Glimelius I., Glimelius B., Nilsson G., Sundstrom C., Enblad G. Mast cell infiltration correlates with poor prognosis in Hodgkin's lymphoma. Br. J. Haematol. 2002, 119:122-124.
56. Nakajima S., Krishnan B., Ota H., Segura A.M., Hattori T., Graham D.Y., Genta R.M. Mast cell involvement in gastritis with or without Helicobacter pylori infection. Gastroenterology 1997, 113:746-754.
57. Noelle R.J., Nowak E.C. Cellular sources and immune functions of interleukin-9. Nat. Rev. Immunol. 2010, 10:683-687.
58. O'Sullivan M., Clayton N., Breslin N.P., Harman I., Bountra C., McLaren A., O'Morain C.A. Increased mast cells in the irritable bowel syndrome. Neurogastroenterol. Motil. Off. J. Eur. Gastrointest. Motil. Soc. 2000, 12:449-457.
59. Padawer J. Editorial: the ins and outs of mast cell function. Am. J. Anat. 1974, 141:299-302.
60. Patella V., Marino I., Arbustini E., Lamparter-Schummert B., Verga L., Adt M., Marone G. Stem cell factor in mast cells and increased mast cell density in idiopathic and ischemic cardiomyopathy. Circulation 1998, 97:971-978.
61. Pennock J.L., Grencis R.K. In vivo exit of c-kit+/CD49d(hi)/beta7+ mucosal mast cell precursors from the bone marrow following infection with the intestinal nematode Trichinella spiralis. Blood 2004, 103:2655-2660.
62. Poglio S., De Toni-Costes F., Arnaud E., Laharrague P., Espinosa E., Casteilla L., Cousin B. Adipose tissue as a dedicated reservoir of functional mast cell progenitors. Stem Cells 2010, 28:2065-2072.
63. Qi X., Hong J., Chaves L., Zhuang Y., Chen Y., Wang D., Chabon J., Graham B., Ohmori K., Li Y., Huang H. Antagonistic regulation by the transcription factors C/EBPalpha and MITF specifies basophil and mast cell fates. Immunity 2013, 39:97-110.
64. Ribatti D., Vacca A., Marzullo A., Nico B., Ria R., Roncali L., Dammacco F. Angiogenesis and mast cell density with tryptase activity increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas. Int. J. Cancer 2000, 85:171-175.
65. Robinson D.S. The role of the T cell in asthma. J. Allergy Clin. Immunol. 2010, 126:1081-1091. quiz 1092-1093.
66. Rodewald H.R., Dessing M., Dvorak A.M., Galli S.J. Identification of a committed precursor for the mast cell lineage. Science 1996, 271:818-822.
67. Rosenkranz A.R., Coxon A., Maurer M., Gurish M.F., Austen K.F., Friend D.S., Galli S.J., Mayadas T.N. Impaired mast cell development and innate immunity in Mac-1 (CD11b/CD18, CR3)-deficient mice. J. Immunol. 1998, 161:6463-6467.
68. Rottem M., Okada T., Goff J.P., Metcalfe D.D. Mast cells cultured from the peripheral blood of normal donors and patients with mastocytosis originate from a CD34+/Fc epsilon RI- cell population. Blood 1994, 84:2489-2496.
69. Sakanaka M., Tanaka S., Sugimoto Y., Ichikawa A. Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix. Am. J. Physiol. Cell Physiol. 2008, 295:C1427-C1433.
70. Sakata-Yanagimoto M., Nakagami-Yamaguchi E., Saito T., Kumano K., Yasutomo K., Ogawa S., Kurokawa M., Chiba S. Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:7839-7844.
71. Scott E.W., Simon M.C., Anastasi J., Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 1994, 265:1573-1577.
72. Shelburne C.P., McCoy M.E., Piekorz R., Sexl V., Roh K.H., Jacobs-Helber S.M., Gillespie S.R., Bailey D.P., Mirmonsef P., Mann M.N., Kashyap M., Wright H.V., Chong H.J., Bouton L.A., Barnstein B., Ramirez C.D., Bunting K.D., Sawyer S., Lantz C.S., Ryan J.J. Stat5 expression is critical for mast cell development and survival. Blood 2003, 102:1290-1297.
73. Sonoda T., Ohno T., Kitamura Y. Concentration of mast-cell progenitors in bone marrow, spleen, and blood of mice determined by limiting dilution analysis. J. Cell Physiol. 1982, 112:136-140.
74. Sonoda T., Hayashi C., Kitamura Y. Presence of mast cell precursors in the yolk sac of mice. Dev. Biol. 1983, 97:89-94.
75. Sonoda T., Kanayama Y., Hara H., Hayashi C., Tadokoro M., Yonezawa T., Kitamura Y. Proliferation of peritoneal mast cells in the skin of W/Wv mice that genetically lack mast cells. J. Exp. Med. 1984, 160:138.
76. Stechschulte D.J., Sharma R., Dileepan K.N., Simpson K.M., Aggarwal N., Clancy J., Jilka R.L. Effect of the mi allele on mast cells, basophils, natural killer cells, and osteoclasts in C57Bl/6J mice. J. Cell Physiol. 1987, 132:565-570.
77. Steelman L.S., Pohnert S.C., Shelton J.G., Franklin R.A., Bertrand F.E., McCubrey J.A. JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis. Leukemia 2004, 18:189-218.
78. Stevens J., Loutit J.F. Mast cells in spotted mutant mice (W Ph mi). Proc. R. Soc. Lond. Ser. B Biol. Sci. 1982, 215:405-409.
79. Suda T., Suda J., Ogawa M. Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations. Proc. Natl. Acad. Sci. U. S. A. 1983, 80:6689-6693.
80. Sugamata M., Ihara T., Uchiide I. Increase of activated mast cells in human endometriosis. Am. J. Reprod. Immunol. 2005, 53:120-125.
81. Sugiyama D., Tanaka M., Kitajima K., Zheng J., Yen H., Murotani T., Yamatodani A., Nakano T. Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation. Blood 2008, 111:1924-1932.
82. Taghon T., Yui M.A., Rothenberg E.V. Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nat. Immunol. 2007, 8:845-855.
83. Terada T., Matsunaga Y. Increased mast cells in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. J. Hepatol. 2000, 33:961-966.
84. Tsai F.Y., Keller G., Kuo F.C., Weiss M., Chen J., Rosenblatt M., Alt F.W., Orkin S.H. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 1994, 371:221-226.
85. Walker B.E. Mast cell turn-over in adult mice. Nature 1961, 192:980-981.
86. Walsh J.C., DeKoter R.P., Lee H.J., Smith E.D., Lancki D.W., Gurish M.F., Friend D.S., Stevens R.L., Anastasi J., Singh H. Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity 2002, 17:665-676.
87. Weller C.L., Collington S.J., Brown J.K., Miller H.R., Al Kashi A., Clark P., Jose P.J., Hartnell A., Williams T.J. Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors. J. Exp. Med. 2005, 201:1961.
88. Weller C.L., Collington S.J., Hartnell A., Conroy D.M., Kaise T., Barker J.E., Wilson M.S., Taylor G.W., Jose P.J., Williams T.J. Chemotactic action of prostaglandin E2 on mouse mast cells acting via the PGE2 receptor 3. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:11712-11717.
89. Xiang Z., Block M., Lofman C., Nilsson G. IgE-mediated mast cell degranulation and recovery monitored by time-lapse photography. J. Allergy Clin. Immunol. 2001, 108:116-121.
90. Yamaguchi M., Lantz C.S., Oettgen H.C., Katona I.M., Fleming T., Miyajima I., Kinet J.P., Galli S.J. IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions. J. Exp. Med. 1997, 185:663-672.
91. Yu M., Tsai M., Tam S.Y., Jones C., Zehnder J., Galli S.J. Mast cells can promote the development of multiple features of chronic asthma in mice. J. Clin. Invest. 2006, 116:1633-1641.