The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for Postintegration Silencing of HIV-1 Gene Expression in Latently Infected Cells

Cell Host and Microbe

Volumn 17, Issue 1, 2015, Pages 107-117

  Gérard, Annabelle ^a,b,c   Ségéral, Emmanuel ^a,b,c   Naughtin, Monica ^a,b,c   Abdouni, Ahmed ^a,b,c   Charmeteau, Bénédicte ^a,b,c   Cheynier, Rémi ^a,b,c   Rain, Jean Christophe ^d   Emiliani, Stéphane ^a,b,c  

^a INSTITUT COCHIN   (France)

^b CNRS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d Hybrigenics SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; IWS1 PROTEIN; LENS EPITHELIUM DERIVED GROWTH FACTOR; PROTEIN P75; SPT6 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; IWS1 PROTEIN, HUMAN; PROTEIN; PSIP1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SUPT6H PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DEPLETION; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VITRO STUDY; LATENT PERIOD; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; TRANSCRIPTION INITIATION SITE; CELL LINE; GENE EXPRESSION REGULATION; HOST PATHOGEN INTERACTION; METABOLISM; PHYSIOLOGY; PROVIRUS; VIRUS DNA CELL DNA INTERACTION; VIRUS LATENCY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE; GENE EXPRESSION REGULATION, VIRAL; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; PROTEINS; PROVIRUSES; TRANSCRIPTION FACTORS; VIRUS INTEGRATION; VIRUS LATENCY;

EID: 84920934149     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2014.12.002     Document Type: Article

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