-
1
-
-
0028301838
-
Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts
-
Adams, M., L. Sharmeen, J. Kimpton, J. M. Romeo, J. V. Garcia, B. M. Peterlin, M. Groudine, and M. Emerman. 1994. Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts. Proc. Natl. Acad. Sci. USA 91:3862-3866.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3862-3866
-
-
Adams, M.1
Sharmeen, L.2
Kimpton, J.3
Romeo, J.M.4
Garcia, J.V.5
Peterlin, B.M.6
Groudine, M.7
Emerman, M.8
-
2
-
-
35348929372
-
HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration
-
Agosto, L. M., J. J. Yu, J. Dai, R. Kaletsky, D. Monie, and U. O'Doherty. 2007. HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration. Virology 368: 60-72.
-
(2007)
Virology
, vol.368
, pp. 60-72
-
-
Agosto, L.M.1
Yu, J.J.2
Dai, J.3
Kaletsky, R.4
Monie, D.5
O'Doherty, U.6
-
3
-
-
0025411135
-
Inactivation of the HIV LTR by DNA CpG methylation: Evidence for a role in latency
-
Bednarik, D. P., J. A. Cook, and P. M. Pitha. 1990. Inactivation of the HIV LTR by DNA CpG methylation: evidence for a role in latency. EMBO J. 9:1157-1164.
-
(1990)
EMBO J
, vol.9
, pp. 1157-1164
-
-
Bednarik, D.P.1
Cook, J.A.2
Pitha, P.M.3
-
4
-
-
0023102324
-
Methylation as a modulator of expression of human immunodeficiency virus
-
Bednarik, D. P., J. D. Mosca, and N. B. K. Raj. 1987. Methylation as a modulator of expression of human immunodeficiency virus. J. Virol. 61: 1253-1257.
-
(1987)
J. Virol
, vol.61
, pp. 1253-1257
-
-
Bednarik, D.P.1
Mosca, J.D.2
Raj, N.B.K.3
-
5
-
-
0027332125
-
Cooper ative inhibition of NF-kappa B and Tat-induced superactivation of human immunodeficiency virus type 1 long terminal repeat
-
Biswas, D. K., C. M. Ahlers, B. J. Dezube, and A. B. Pardee. 1993. Cooper ative inhibition of NF-kappa B and Tat-induced superactivation of human immunodeficiency virus type 1 long terminal repeat. Proc. Natl. Acad. Sci. USA 90:11044-11048.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11044-11048
-
-
Biswas, D.K.1
Ahlers, C.M.2
Dezube, B.J.3
Pardee, A.B.4
-
6
-
-
0035050963
-
Generation of HIV latency during thymopoiesis
-
Brooks, D. G., S. G. Kitchen, C. M. Kitchen, D. D. Scripture-Adams, and J. A. Zack. 2001. Generation of HIV latency during thymopoiesis. Nat. Med. 7:459-464.
-
(2001)
Nat. Med
, vol.7
, pp. 459-464
-
-
Brooks, D.G.1
Kitchen, S.G.2
Kitchen, C.M.3
Scripture-Adams, D.D.4
Zack, J.A.5
-
7
-
-
0026568640
-
Integration of human immunodefi ciency virus DNA: Adduct interference analysis of required DNA sites
-
Bushman, F. D., and R. Craigie. 1992. Integration of human immunodefi ciency virus DNA: adduct interference analysis of required DNA sites. Proc. Natl. Acad. Sci. USA 89:3458-3462.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3458-3462
-
-
Bushman, F.D.1
Craigie, R.2
-
8
-
-
0034492812
-
Therapeutic targeting of human immunodeficiency virus type-1 latency: Current clinical realities and future scientific possibilities
-
Butera, S. T. 2000. Therapeutic targeting of human immunodeficiency virus type-1 latency: current clinical realities and future scientific possibilities. Antivir. Res. 48:143-176.
-
(2000)
Antivir. Res
, vol.48
, pp. 143-176
-
-
Butera, S.T.1
-
9
-
-
0032006882
-
Differ ential expression of BCL-6, CD138/syndecan-l, and Epstein-Barr virus-en coded latent membrane protein-1 identifies distinct histogenetic subsets of acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas
-
Carbone, A., G. Gaidano, A. Gloghini, L. M. Larocca, D. Capello, V. Canzonieri, A. Antinori, U. Tirelli, B. Falini, and R. Dalla-Favera. 1998. Differ ential expression of BCL-6, CD138/syndecan-l, and Epstein-Barr virus-en coded latent membrane protein-1 identifies distinct histogenetic subsets of acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas. Blood 91:747-755.
-
(1998)
Blood
, vol.91
, pp. 747-755
-
-
Carbone, A.1
Gaidano, G.2
Gloghini, A.3
Larocca, L.M.4
Capello, D.5
Canzonieri, V.6
Antinori, A.7
Tirelli, U.8
Falini, B.9
Dalla-Favera, R.10
-
10
-
-
0035254498
-
Expression profile of MUM1/IRF4, BCL-6, and CD138/syndecan-l defines novel histogenetic subsets of human immunodeficiency virus-related lymphomas
-
Carbone, A., A. Gloghini, L. M. Larocca, D. Capello, F. Pierconti, V. Can-zonieri, U. Tirelli, R. Dalla-Favera, and G. Gaidano. 2001. Expression profile of MUM1/IRF4, BCL-6, and CD138/syndecan-l defines novel histogenetic subsets of human immunodeficiency virus-related lymphomas. Blood 97: 744-751.
-
(2001)
Blood
, vol.97
, pp. 744-751
-
-
Carbone, A.1
Gloghini, A.2
Larocca, L.M.3
Capello, D.4
Pierconti, F.5
Can-zonieri, V.6
Tirelli, U.7
Dalla-Favera, R.8
Gaidano, G.9
-
11
-
-
15144342918
-
Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection
-
Cavert, W., D. W. Notermans, K. Staskus, S. W. Wietgrefe, M. Zupancic, K. Gebhard, K. Henry, Z. Q. Zhang, R. Mills, H. McDade, C. M. Schuwirth, J. Goudsmit, S. A. Danner, and A. T. Haase. 1997. Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection. Science 276: 960-964.
-
(1997)
Science
, vol.276
, pp. 960-964
-
-
Cavert, W.1
Notermans, D.W.2
Staskus, K.3
Wietgrefe, S.W.4
Zupancic, M.5
Gebhard, K.6
Henry, K.7
Zhang, Z.Q.8
Mills, R.9
McDade, H.10
Schuwirth, C.M.11
Goudsmit, J.12
Danner, S.A.13
Haase, A.T.14
-
12
-
-
0030610544
-
The κB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth
-
Chen, B. K., M. B. Feinberg, and D. Baltimore. 1997. The κB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth. J. Virol. 71:5495-5504.
-
(1997)
J. Virol
, vol.71
, pp. 5495-5504
-
-
Chen, B.K.1
Feinberg, M.B.2
Baltimore, D.3
-
13
-
-
0030913366
-
Quanti fication of latent tissue reservoirs and total body viral load in HIV-1 infec tion
-
Chun, T. W., L. Carruth, D. Finzi, X. Shen, J. A. DiGiuseppe, H. Taylor, M. Hermankova, K. Chadwick, J. Margolick, T. C. Quinn, Y. H. Kuo, R. Brookmeyer, M. A. Zeiger, P. Barditch-Crovo, and R. F. Siliciano. 1997. Quanti fication of latent tissue reservoirs and total body viral load in HIV-1 infec tion. Nature 387:183-188.
-
(1997)
Nature
, vol.387
, pp. 183-188
-
-
Chun, T.W.1
Carruth, L.2
Finzi, D.3
Shen, X.4
DiGiuseppe, J.A.5
Taylor, H.6
Hermankova, M.7
Chadwick, K.8
Margolick, J.9
Quinn, T.C.10
Kuo, Y.H.11
Brookmeyer, R.12
Zeiger, M.A.13
Barditch-Crovo, P.14
Siliciano, R.F.15
-
14
-
-
0033914367
-
Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy
-
Chun, T. W., R. T. Davey, Jr., M. Ostrowski, J. Shawn Justement, D. Engel, J. I. Mullins, and A. S. Fauci. 2000. Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy. Nat. Med. 6:757-761.
-
(2000)
Nat. Med
, vol.6
, pp. 757-761
-
-
Chun, T.W.1
Davey Jr., R.T.2
Ostrowski, M.3
Shawn Justement, J.4
Engel, D.5
Mullins, J.I.6
Fauci, A.S.7
-
15
-
-
0032555117
-
Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection
-
Chun, T. W., D. Engel, M. M. Berrey, T. Shea, L. Corey, and A. S. Fauci. 1998. Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection. Proc. Natl. Acad. Sci. USA 95:8869-8873.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8869-8873
-
-
Chun, T.W.1
Engel, D.2
Berrey, M.M.3
Shea, T.4
Corey, L.5
Fauci, A.S.6
-
16
-
-
0032490570
-
Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines
-
Chun, T. W., D. Engel, S. B. Mizell, L. A. Ehler, and A. S. Fauci. 1998. Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines. J. Exp. Med. 188:83-91.
-
(1998)
J. Exp. Med
, vol.188
, pp. 83-91
-
-
Chun, T.W.1
Engel, D.2
Mizell, S.B.3
Ehler, L.A.4
Fauci, A.S.5
-
17
-
-
0033031218
-
Effect of interleukin-2 on the pool of latently infected, resting CD4+ T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy
-
Chun, T. W., D. Engel, S. B. Mizell, C. W. Hallahan, M. Fischette, S. Park, R. T. Davey, Jr., M. Dybul, J. A. Kovacs, J. A. Metcalf, J. M. Mican, M. M. Berrey, L. Corey, H. C. Lane, and A. S. Fauci. 1999. Effect of interleukin-2 on the pool of latently infected, resting CD4+ T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy. Nat. Med. 5:651-655.
-
(1999)
Nat. Med
, vol.5
, pp. 651-655
-
-
Chun, T.W.1
Engel, D.2
Mizell, S.B.3
Hallahan, C.W.4
Fischette, M.5
Park, S.6
Davey Jr., R.T.7
Dybul, M.8
Kovacs, J.A.9
Metcalf, J.A.10
Mican, J.M.11
Berrey, M.M.12
Corey, L.13
Lane, H.C.14
Fauci, A.S.15
-
18
-
-
0033613070
-
Latent reservoirs of HIV: Obstacles to the eradication of virus
-
Chun, T. W., and A. S. Fauci. 1999. Latent reservoirs of HIV: obstacles to the eradication of virus. Proc. Natl. Acad. Sci. USA 96:10958-10961.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10958-10961
-
-
Chun, T.W.1
Fauci, A.S.2
-
19
-
-
0028792184
-
In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency
-
Chun, T. W., D. Finzi, J. Margolick, K. Chadwick, D. Schwartz, and R. F. Siliciano. 1995. In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. Nat. Med. 1:1284-1290.
-
(1995)
Nat. Med
, vol.1
, pp. 1284-1290
-
-
Chun, T.W.1
Finzi, D.2
Margolick, J.3
Chadwick, K.4
Schwartz, D.5
Siliciano, R.F.6
-
20
-
-
34249883292
-
Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: Implications for eradication of virus
-
Chun, T. W., J. S. Justement, S. Moir, C. W. Hallahan, J. Maenza, J. I. Mullins, A. C. Collier, L. Corey, and A. S. Fauci. 2007. Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus. J. Infect. Dis. 195:1762-1764.
-
(2007)
J. Infect. Dis
, vol.195
, pp. 1762-1764
-
-
Chun, T.W.1
Justement, J.S.2
Moir, S.3
Hallahan, C.W.4
Maenza, J.5
Mullins, J.I.6
Collier, A.C.7
Corey, L.8
Fauci, A.S.9
-
21
-
-
0030659177
-
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
-
Chun, T. W., L. Stuyver, S. B. Mizell, L. A. Ehler, J. A. Mican, M. Baseler, A. L. Lloyd, M. A. Nowak, and A. S. Fauci. 1997. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc. Natl. Acad. Sci. USA 94:13193-13197.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13193-13197
-
-
Chun, T.W.1
Stuyver, L.2
Mizell, S.B.3
Ehler, L.A.4
Mican, J.A.5
Baseler, M.6
Lloyd, A.L.7
Nowak, M.A.8
Fauci, A.S.9
-
22
-
-
0034916701
-
Temporal gene regulation during HIV-1 infection of human CD4+ T cells
-
Corbeil, J., D. Sheeter, D. Genini, S. Rought, L. Leoni, P. Du, M. Ferguson, D. R. Masys, J. B. Welsh, J. L. Fink, R. Sasik, D. Huang, J. Drenkow, D. D. Richman, and T. Gingeras. 2001. Temporal gene regulation during HIV-1 infection of human CD4+ T cells. Genome Res. 11:1198-1204.
-
(2001)
Genome Res
, vol.11
, pp. 1198-1204
-
-
Corbeil, J.1
Sheeter, D.2
Genini, D.3
Rought, S.4
Leoni, L.5
Du, P.6
Ferguson, M.7
Masys, D.R.8
Welsh, J.B.9
Fink, J.L.10
Sasik, R.11
Huang, D.12
Drenkow, J.13
Richman, D.D.14
Gingeras, T.15
-
23
-
-
0033929108
-
The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1
-
Coull, J. J., F. Romerio, J. M. Sun, J. L. Volker, K. M. Galvin, J. R. Davie, Y. Shi, U. Hansen, and D. M. Margolis. 2000. The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. J. Virol. 74:6790-6799.
-
(2000)
J. Virol
, vol.74
, pp. 6790-6799
-
-
Coull, J.J.1
Romerio, F.2
Sun, J.M.3
Volker, J.L.4
Galvin, K.M.5
Davie, J.R.6
Shi, Y.7
Hansen, U.8
Margolis, D.M.9
-
24
-
-
0027446270
-
The c-rel protooncogene product represses NF-kappa B p65-mediated transcrip tional activation of the long terminal repeat of type 1 human immunodefi ciency virus
-
Doerre, S., P. Sista, S. C. Sun, D. W. Ballard, and W. C. Greene. 1993. The c-rel protooncogene product represses NF-kappa B p65-mediated transcrip tional activation of the long terminal repeat of type 1 human immunodefi ciency virus. Proc. Natl. Acad. Sci. USA 90:1023-1027.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1023-1027
-
-
Doerre, S.1
Sista, P.2
Sun, S.C.3
Ballard, D.W.4
Greene, W.C.5
-
25
-
-
0001488150
-
Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kB sites in the long terminal repeat
-
Duh, E. J., W. J. Maury, T. M. Folks, A. S. Fauci, and A. B. Rabson. 1989. Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kB sites in the long terminal repeat. Proc. Natl. Acad. Sci. USA 86:5974-5978.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5974-5978
-
-
Duh, E.J.1
Maury, W.J.2
Folks, T.M.3
Fauci, A.S.4
Rabson, A.B.5
-
26
-
-
0028133583
-
HIV replication in chronically infected macrophages is not inhibited by the Tat inhibitors Ro-5-3335 and Ro-24-7429
-
Dunne, A. L., H. Siregar, J. Mills, and S. M. Crowe. 1994. HIV replication in chronically infected macrophages is not inhibited by the Tat inhibitors Ro-5-3335 and Ro-24-7429. J. Leukoc. Biol. 56:369-373.
-
(1994)
J. Leukoc. Biol
, vol.56
, pp. 369-373
-
-
Dunne, A.L.1
Siregar, H.2
Mills, J.3
Crowe, S.M.4
-
27
-
-
0032953920
-
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
-
Finzi, D., J. Blankson, J. D. Siliciano, J. B. Margolick, K. Chadwick, T. Pierson, K. Smith, J. Lisziewicz, F. Lori, C. Flexner, T. C. Quinn, R. E. Chaisson, E. Rosenberg, B. Walker, S. Gange, J. Gallant, and R. F. Siliciano. 1999. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat. Med. 5:512-517.
-
(1999)
Nat. Med
, vol.5
, pp. 512-517
-
-
Finzi, D.1
Blankson, J.2
Siliciano, J.D.3
Margolick, J.B.4
Chadwick, K.5
Pierson, T.6
Smith, K.7
Lisziewicz, J.8
Lori, F.9
Flexner, C.10
Quinn, T.C.11
Chaisson, R.E.12
Rosenberg, E.13
Walker, B.14
Gange, S.15
Gallant, J.16
Siliciano, R.F.17
-
28
-
-
0010472999
-
Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone
-
Folks, T. M, K. A. Clouse, J. Justement, A. Rabson, E. Duh, J. H. Kehrl, and A. S. Fauci. 1989. Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc. Natl. Acad. Sci. USA 86:2365-2368.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 2365-2368
-
-
Folks, T.M.1
Clouse, K.A.2
Justement, J.3
Rabson, A.4
Duh, E.5
Kehrl, J.H.6
Fauci, A.S.7
-
29
-
-
0023874174
-
Characterization of a promonocyte clone chronically infected with HIV and inducible by 13-phorbol-12-myristate acetate
-
Folks, T. M, J. Justement, A. Kinter, S. Schnittman, J. Orenstein, G. Poli, and A S. Fauci. 1988. Characterization of a promonocyte clone chronically infected with HIV and inducible by 13-phorbol-12-myristate acetate. J. Im munol. 140:1117-1122.
-
(1988)
J. Im munol
, vol.140
, pp. 1117-1122
-
-
Folks, T.M.1
Justement, J.2
Kinter, A.3
Schnittman, S.4
Orenstein, J.5
Poli, G.6
Fauci, A.S.7
-
30
-
-
2642523580
-
+ T cells from human immunodeficiency virus type 1 (HlV-l)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes
-
+ T cells from human immunodeficiency virus type 1 (HlV-l)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J. Virol. 78:6122-6133.
-
(2004)
J. Virol
, vol.78
, pp. 6122-6133
-
-
Han, Y.1
Lassen, K.2
Monie, D.3
Sedaghat, A.R.4
Shimoji, S.5
Liu, X.6
Pierson, T.C.7
Margolick, J.B.8
Siliciano, R.F.9
Siliciano, J.D.10
-
31
-
-
48649085472
-
Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough
-
Han, Y., Y. B. Lin, W. An, J. Xu, H. C. Yang, K. O'Connell, D. Dordai, J. D. Boeke, J. D. Siliciano, and R. F. Siliciano. 2008. Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough. Cell Host Microbe 4:134-146.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 134-146
-
-
Han, Y.1
Lin, Y.B.2
An, W.3
Xu, J.4
Yang, H.C.5
O'Connell, K.6
Dordai, D.7
Boeke, J.D.8
Siliciano, J.D.9
Siliciano, R.F.10
-
32
-
-
33744991740
-
TGN1412: Scrutinizing preclinical trials of antibody-based medicines
-
Hansen, S., and R. G. Leslie. 2006. TGN1412: scrutinizing preclinical trials of antibody-based medicines. Nature 441:282.
-
(2006)
Nature
, vol.441
, pp. 282
-
-
Hansen, S.1
Leslie, R.G.2
-
33
-
-
0028785496
-
A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection
-
Haubrich, R. H., C. Flexner, M. M. Lederman, M. Hirsch, C. P. Pettinelli, R. Ginsberg, P. Lietman, F. M. Hamzeh, S. A. Spector, D. D. Richman, et al. 1995. A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection. J. Infect. Dis. 172:1246-1252.
-
(1995)
J. Infect. Dis
, vol.172
, pp. 1246-1252
-
-
Haubrich, R.H.1
Flexner, C.2
Lederman, M.M.3
Hirsch, M.4
Pettinelli, C.P.5
Ginsberg, R.6
Lietman, P.7
Hamzeh, F.M.8
Spector, S.A.9
Richman, D.D.10
-
34
-
-
33750426515
-
5′ long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signals
-
Ishida, T., A. Hamano, T. Koiwa, and T. Watanabe. 2006. 5′ long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signals. Retrovirology 3:69.
-
(2006)
Retrovirology
, vol.3
, pp. 69
-
-
Ishida, T.1
Hamano, A.2
Koiwa, T.3
Watanabe, T.4
-
35
-
-
34247585019
-
-
Jones, J., J. Rodgers, M. Heil, J. May, L. White, J. A. Maddry, T. M. Fletcher III, G. M. Shaw, J. L. Hartman IV, and O. Kutsch. 2007. High throughput drug screening for human immunodeficiency virus type 1 reactivating com pounds. Assay Drag Dev. Technol. 5:181-189.
-
Jones, J., J. Rodgers, M. Heil, J. May, L. White, J. A. Maddry, T. M. Fletcher III, G. M. Shaw, J. L. Hartman IV, and O. Kutsch. 2007. High throughput drug screening for human immunodeficiency virus type 1 reactivating com pounds. Assay Drag Dev. Technol. 5:181-189.
-
-
-
-
36
-
-
36448976528
-
Optimization of HIV-1 infectivity assays
-
Jones, J., W. Whitford, F. Wagner, and O. Kutsch. 2007. Optimization of HIV-1 infectivity assays. BioTechniques 43:589-594.
-
(2007)
BioTechniques
, vol.43
, pp. 589-594
-
-
Jones, J.1
Whitford, W.2
Wagner, F.3
Kutsch, O.4
-
37
-
-
0037446948
-
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
-
Jordan, A, D. Bisgrove, and E. Verdin. 2003. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. EMBO J. 22:1868-1877.
-
(2003)
EMBO J
, vol.22
, pp. 1868-1877
-
-
Jordan, A.1
Bisgrove, D.2
Verdin, E.3
-
38
-
-
0035794637
-
The site of HIV-1 integra tion in the human genome determines basal transcriptional activity and response to Tat transactivation
-
Jordan, A., P. Defechereux, and E. Verdin. 2001. The site of HIV-1 integra tion in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J. 20:1726-1738.
-
(2001)
EMBO J
, vol.20
, pp. 1726-1738
-
-
Jordan, A.1
Defechereux, P.2
Verdin, E.3
-
39
-
-
0023513563
-
Antitermination of transcription within the long terminal repeat of HIV-1 by tat gene product
-
Kao, S. Y., A F. Caiman, P. A. Luciw, and B. M. Peterlin. 1987. Antitermination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature 330:489-493.
-
(1987)
Nature
, vol.330
, pp. 489-493
-
-
Kao, S.Y.1
Caiman, A.F.2
Luciw, P.A.3
Peterlin, B.M.4
-
40
-
-
0037111060
-
Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy
-
Kulkosky, J., G. Nunnari, M. Otero, S. Calarota, G. Dornadula, H. Zhang, A. Malin, J. Sullivan, Y. Xu, J. DeSimone, T. Babinchak, J. Stern, W. Cavert, A. Haase, and R. J. Pomerantz. 2002. Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy. J. Infect. Dis. 186:1403-1411.
-
(2002)
J. Infect. Dis
, vol.186
, pp. 1403-1411
-
-
Kulkosky, J.1
Nunnari, G.2
Otero, M.3
Calarota, S.4
Dornadula, G.5
Zhang, H.6
Malin, A.7
Sullivan, J.8
Xu, Y.9
DeSimone, J.10
Babinchak, T.11
Stern, J.12
Cavert, W.13
Haase, A.14
Pomerantz, R.J.15
-
41
-
-
0036337415
-
Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency
-
Kutsch, O., E. N. Benveniste, G. M. Shaw, and D. N. Levy. 2002. Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency. J. Virol. 76:8776-8786.
-
(2002)
J. Virol
, vol.76
, pp. 8776-8786
-
-
Kutsch, O.1
Benveniste, E.N.2
Shaw, G.M.3
Levy, D.N.4
-
42
-
-
23744500093
-
Depletion of latent HIV-1 infection in vivo: A proof-of-concept study
-
Lehrman, G., I. B. Hogue, S. Palmer, C. Jennings, C. A. Spina, A. Wiegand, A. L. Landay, R. W. Coombs, D. D. Richman, J. W. Mellors, J. M. Coffin, R. J. Bosch, and D. M. Margolis. 2005. Depletion of latent HIV-1 infection in vivo: a proof-of-concept study. Lancet 366:549-555.
-
(2005)
Lancet
, vol.366
, pp. 549-555
-
-
Lehrman, G.1
Hogue, I.B.2
Palmer, S.3
Jennings, C.4
Spina, C.A.5
Wiegand, A.6
Landay, A.L.7
Coombs, R.W.8
Richman, D.D.9
Mellors, J.W.10
Coffin, J.M.11
Bosch, R.J.12
Margolis, D.M.13
-
43
-
-
48649089113
-
Transcriptional interfer ence antagonizes proviral gene expression to promote HIV latency
-
Lenasi, T., X. Contreras, and B. M. Peterlin. 2008. Transcriptional interfer ence antagonizes proviral gene expression to promote HIV latency. Cell Host Microbe 4:123-133.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 123-133
-
-
Lenasi, T.1
Contreras, X.2
Peterlin, B.M.3
-
44
-
-
1642447695
-
Dynamics of HIV-1 recombination in its natural target cells
-
Levy, D. N., G. M. Aldrovandi, O. Kutsch, and G. M. Shaw. 2004. Dynamics of HIV-1 recombination in its natural target cells. Proc. Natl. Acad. Sci. USA 101:4204-4209.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4204-4209
-
-
Levy, D.N.1
Aldrovandi, G.M.2
Kutsch, O.3
Shaw, G.M.4
-
45
-
-
0031811880
-
Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-γ) promoter and subsequent downregulation of IFN-γ production
-
Mikovits, J. A., H. A. Young, P. Vertino, J. P. Issa, P. M. Pitha, S. Turcoski-Corrales, D. D. Taub, C. L. Petrow, S. B. Baylin, and F. W. Ruscetti. 1998. Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-γ) promoter and subsequent downregulation of IFN-γ production. Mol. Cell. Biol. 18:5166-5177.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 5166-5177
-
-
Mikovits, J.A.1
Young, H.A.2
Vertino, P.3
Issa, J.P.4
Pitha, P.M.5
Turcoski-Corrales, S.6
Taub, D.D.7
Petrow, C.L.8
Baylin, S.B.9
Ruscetti, F.W.10
-
46
-
-
0023176085
-
An inducible transcription factor acti vates expression of human immunodeficiency virus in T cells
-
Nabel, G., and D. Baltimore. 1987. An inducible transcription factor acti vates expression of human immunodeficiency virus in T cells. Nature 326: 711-713.
-
(1987)
Nature
, vol.326
, pp. 711-713
-
-
Nabel, G.1
Baltimore, D.2
-
47
-
-
0036340605
-
Molecular characterization of preintegration latency in human immu nodeficiency virus type 1 infection
-
Pierson, T. C, Y. Zhou, T. L. Kieffer, C. T. Ruff, C. Buck, and R. F. Siliciano. 2002. Molecular characterization of preintegration latency in human immu nodeficiency virus type 1 infection. J. Virol. 76:8518-8531.
-
(2002)
J. Virol
, vol.76
, pp. 8518-8531
-
-
Pierson, T.C.1
Zhou, Y.2
Kieffer, T.L.3
Ruff, C.T.4
Buck, C.5
Siliciano, R.F.6
-
48
-
-
0037378601
-
Transcriptional suppres sion of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation
-
Pion, M., A. Jordan, A. Biancotto, F. Dequiedt, F. Gondois-Rey, S. Rondeau, R. Vigne, J. Hejnar, E. Verdin, and I. Hirsch. 2003. Transcriptional suppres sion of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation. J. Virol. 77:4025-4032.
-
(2003)
J. Virol
, vol.77
, pp. 4025-4032
-
-
Pion, M.1
Jordan, A.2
Biancotto, A.3
Dequiedt, F.4
Gondois-Rey, F.5
Rondeau, S.6
Vigne, R.7
Hejnar, J.8
Verdin, E.9
Hirsch, I.10
-
49
-
-
0036839054
-
Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-κB and inhibitors of deacetylases: Potential per spectives for the development of therapeutic strategies
-
Quivy, V., E. Adam, Y. Collette, D. Demonte, A. Chariot, C. Vanhulle, B. Berkhout, R. Castellano, Y. de Launoit, A. Burny, J. Piette, V. Bours, and C. Van Lint. 2002. Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-κB and inhibitors of deacetylases: potential per spectives for the development of therapeutic strategies. J. Virol. 76:11091-11103.
-
(2002)
J. Virol
, vol.76
, pp. 11091-11103
-
-
Quivy, V.1
Adam, E.2
Collette, Y.3
Demonte, D.4
Chariot, A.5
Vanhulle, C.6
Berkhout, B.7
Castellano, R.8
de Launoit, Y.9
Burny, A.10
Piette, J.11
Bours, V.12
Van Lint, C.13
-
51
-
-
0037162715
-
HIV-1 integration in the human genome favors active genes and local hotspots
-
Schroder, A. R., P. Shinn, H. Chen, C. Berry, J. R. Ecker, and F. Bushman. 2002. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110:521-529.
-
(2002)
Cell
, vol.110
, pp. 521-529
-
-
Schroder, A.R.1
Shinn, P.2
Chen, H.3
Berry, C.4
Ecker, J.R.5
Bushman, F.6
-
52
-
-
0031455415
-
-
Sheridan, P. L., T. P. Mayall, E. Verdin, and K. A, Jones. 1997. Histone acetyltransferases regulate HIV-1 enhancer activity in vitro. Genes Dev. 11:3327-3340.
-
Sheridan, P. L., T. P. Mayall, E. Verdin, and K. A, Jones. 1997. Histone acetyltransferases regulate HIV-1 enhancer activity in vitro. Genes Dev. 11:3327-3340.
-
-
-
-
53
-
-
0038579210
-
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
-
Siliciano, J. D., J. Kajdas, D. Finzi, T. C. Quinn, K. Chadwick, J. B. Mar golick, C. Kovacs, S. J. Gange, and R. F. Siliciano. 2003. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat. Med. 9:727-728.
-
(2003)
Nat. Med
, vol.9
, pp. 727-728
-
-
Siliciano, J.D.1
Kajdas, J.2
Finzi, D.3
Quinn, T.C.4
Chadwick, K.5
Mar golick, J.B.6
Kovacs, C.7
Gange, S.J.8
Siliciano, R.F.9
-
54
-
-
33847642822
-
Stability of the latent reservoir for HIV-1 in patients receiving valproic acid
-
Siliciano, J. D., J. Lai, M. Callender, E. Pitt, H. Zhang, J. B. Margolick, J. E. Gallant, J. Cofrancesco, Jr., R. D. Moore, S. J. Gange, and R. F. Siliciano. 2007. Stability of the latent reservoir for HIV-1 in patients receiving valproic acid. J. Infect. Dis. 195:833-836.
-
(2007)
J. Infect. Dis
, vol.195
, pp. 833-836
-
-
Siliciano, J.D.1
Lai, J.2
Callender, M.3
Pitt, E.4
Zhang, H.5
Margolick, J.B.6
Gallant, J.E.7
Cofrancesco Jr., J.8
Moore, R.D.9
Gange, S.J.10
Siliciano, R.F.11
-
55
-
-
33644848195
-
Targeting HIV reservoirs with valproic acid
-
Siliciano, J. M., and R. F. Siliciano. 2005. Targeting HIV reservoirs with valproic acid. Hopkins HIV Rep. 17:8-9.
-
(2005)
Hopkins HIV Rep
, vol.17
, pp. 8-9
-
-
Siliciano, J.M.1
Siliciano, R.F.2
-
56
-
-
27344442122
-
Valproic acid and HIV-1 latency: Beyond the sound bite
-
Smith, S. M. 2005. Valproic acid and HIV-1 latency: beyond the sound bite. Retrovirology 2:56.
-
(2005)
Retrovirology
, vol.2
, pp. 56
-
-
Smith, S.M.1
-
57
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
Suntharalingam, G., M. R. Perry, S. Ward, S. J. Brett, A. Castello-Cortes, M. D. Brunner, and N. Panoskaltsis. 2006. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N. Engl. J. Med. 355: 1018-1028.
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
Brunner, M.D.6
Panoskaltsis, N.7
-
58
-
-
27644599799
-
+ T cells in the absence of activating stimuli
-
+ T cells in the absence of activating stimuli. J. Virol. 79:14179-14188.
-
(2005)
J. Virol
, vol.79
, pp. 14179-14188
-
-
Swiggard, W.J.1
Baytop, C.2
Yu, J.J.3
Dai, J.4
Li, C.5
Schretzenmair, R.6
Theodosopoulos, T.7
O'Doherty, U.8
-
59
-
-
0346422481
-
Mutation of CpGs in the murine stem cell virus retroviral vector long terminal repeat represses si lencing in embryonic stem cells
-
Swindle, C. S., H. G. Kim, and C. A. Klug. 2004. Mutation of CpGs in the murine stem cell virus retroviral vector long terminal repeat represses si lencing in embryonic stem cells. J. Biol. Chem. 279:34-41.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 34-41
-
-
Swindle, C.S.1
Kim, H.G.2
Klug, C.A.3
-
60
-
-
0029919356
-
Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
-
Van Lint, C, S. Emiliani, M. Ott, and E. Verdin. 1996. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J. 15:1112-1120.
-
(1996)
EMBO J
, vol.15
, pp. 1112-1120
-
-
Van Lint, C.1
Emiliani, S.2
Ott, M.3
Verdin, E.4
-
61
-
-
30444431914
-
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
-
Williams, S. A., L. F. Chen, H. Kwon, C. M. Ruiz-Jarabo, E. Verdin, and W. C. Greene. 2006. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 25:139-149.
-
(2006)
EMBO J
, vol.25
, pp. 139-149
-
-
Williams, S.A.1
Chen, L.F.2
Kwon, H.3
Ruiz-Jarabo, C.M.4
Verdin, E.5
Greene, W.C.6
-
62
-
-
0027483712
-
HIV-1 latency due to the site of proviral integration
-
Winslow, B. J., R. J. Pomerantz, O. Bagasra, and D. Trono. 1993. HIV-1 latency due to the site of proviral integration. Virology 196:849-854.
-
(1993)
Virology
, vol.196
, pp. 849-854
-
-
Winslow, B.J.1
Pomerantz, R.J.2
Bagasra, O.3
Trono, D.4
|