메뉴 건너뛰기




Volumn 85, Issue 11, 2011, Pages 5384-5393

Influence of host gene transcription level and orientation on HIV-1 latency in a primary-cell model

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INTRON; NONHUMAN; PRIORITY JOURNAL; SERIAL ANALYSIS OF GENE EXPRESSION; UPREGULATION; VIRUS DNA CELL DNA INTERACTION; VIRUS LATENCY; VIRUS TRANSCRIPTION;

EID: 79956082418     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02536-10     Document Type: Article
Times cited : (97)

References (63)
  • 1
    • 0019994521 scopus 로고
    • Promoter occlusion: transcription through a promoter may inhibit its activity
    • Adhya, S., and M. Gottesman. 1982. Promoter occlusion: transcription through a promoter may inhibit its activity. Cell 29:939-944.
    • (1982) Cell , vol.29 , pp. 939-944
    • Adhya, S.1    Gottesman, M.2
  • 2
    • 70049090006 scopus 로고    scopus 로고
    • CpG methylation controls reactivation of HIV from latency
    • doi:10.1371/journal.ppat.1000554
    • Blazkova, J., et al. 2009. CpG methylation controls reactivation of HIV from latency. PLoS Pathog. 5:e1000554. doi:10.1371/journal.ppat.1000554.
    • (2009) PLoS Pathog , vol.5 , pp. 1000554
    • Blazkova, J.1
  • 3
    • 0024276882 scopus 로고
    • The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV
    • Bohnlein, E., et al. 1988. The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Cell 53:827-836.
    • (1988) Cell , vol.53 , pp. 827-836
    • Bohnlein, E.1
  • 4
    • 59449101108 scopus 로고    scopus 로고
    • Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells
    • doi:10.1182/blood-2008-07-168393
    • Bosque, A., and V. Planelles. 2009. Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells. Blood 113:58-65. doi:10.1182/blood-2008-07-168393.
    • (2009) Blood , vol.113 , pp. 8-65
    • Bosque, A.1    Planelles, V.2
  • 6
    • 2942574509 scopus 로고    scopus 로고
    • Transcriptional interference between convergent promoters caused by elongation over the promoter
    • doi:10.1016/j.molcel.2004.05.010
    • Callen, B. P., K. E. Shearwin, and J. B. Egan. 2004. Transcriptional interference between convergent promoters caused by elongation over the promoter. Mol. Cell 14:647-656. doi:10.1016/j.molcel.2004.05.010.
    • (2004) Mol. Cell , vol.14 , pp. 47-656
    • Callen, B.P.1    Shearwin, K.E.2    Egan, J.B.3
  • 7
    • 0028792184 scopus 로고
    • In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency
    • Chun, T. W., et al. 1995. In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. Nat. Med. 1:1284-1290.
    • (1995) Nat. Med. , vol.1 , pp. 284-1290
    • Chun, T.W.1
  • 8
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • doi:10.1038/387183a0
    • Chun, T. W., et al. 1997. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387:183-188. doi:10.1038/387183a0.
    • (1997) Nature , vol.387 , pp. 83-188
    • Chun, T.W.1
  • 9
    • 0030659177 scopus 로고    scopus 로고
    • Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
    • Chun, T. W., et al. 1997. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc. Natl. Acad. Sci. U. S. A. 94:13193-13197.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 13193-13197
    • Chun, T.W.1
  • 10
    • 0037452711 scopus 로고    scopus 로고
    • Gene expression and viral production in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals
    • doi:10.1073/pnas.0437640100
    • Chun, T. W., et al. 2003. Gene expression and viral production in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals. Proc. Natl. Acad. Sci. U. S. A. 100:1908-1913. doi:10.1073/pnas.0437640100.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 908-1913
    • Chun, T.W.1
  • 11
    • 0033929108 scopus 로고    scopus 로고
    • The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1
    • Coull, J. J., et al. 2000. The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. J. Virol. 74:6790-6799.
    • (2000) J. Virol. , vol.74 , pp. 6790-6799
    • Coull, J.J.1
  • 12
    • 0030856701 scopus 로고    scopus 로고
    • The HIV transactivator TAT binds to the CDKactivating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II
    • Cujec, T. P., et al. 1997. The HIV transactivator TAT binds to the CDKactivating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. Genes Dev. 11:2645-2657.
    • (1997) Genes Dev , vol.11 , pp. 2645-2657
    • Cujec, T.P.1
  • 13
    • 0001488150 scopus 로고
    • Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat
    • Duh, E. J., W. J. Maury, T. M. Folks, A. S. Fauci, and A. B. Rabson. 1989. Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat. Proc. Natl. Acad. Sci. U. S. A. 86:5974-5978.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 5974-5978
    • Duh, E.J.1    Maury, W.J.2    Folks, T.M.3    Fauci, A.S.4    Rabson, A.B.5
  • 14
    • 14444273439 scopus 로고    scopus 로고
    • Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
    • Finzi, D., et al. 1997. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278:1295-1300.
    • (1997) Science , vol.278 , pp. 1295-1300
    • Finzi, D.1
  • 15
    • 0032953920 scopus 로고    scopus 로고
    • Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • doi:10. 1038/8394
    • Finzi, D., et al. 1999. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat. Med. 5:512-517. doi:10.1038/8394.
    • (1999) Nat. Med. , vol.5 , pp. 512-517
    • Finzi, D.1
  • 16
    • 0346340064 scopus 로고    scopus 로고
    • The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes
    • doi:10. 1038/nature02171
    • Ganesh, L., et al. 2003. The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. Nature 426:853-857. doi:10.1038/nature02171.
    • (2003) Nature , vol.426 , pp. 853-857
    • Ganesh, L.1
  • 17
    • 0032029996 scopus 로고    scopus 로고
    • Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter
    • Greger, I. H., F. Demarchi, M. Giacca, and N. J. Proudfoot. 1998. Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter. Nucleic Acids Res. 26:1294-1301.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1294-1301
    • Greger, I.H.1    Demarchi, F.2    Giacca, M.3    Proudfoot, N.J.4
  • 18
    • 2642523580 scopus 로고    scopus 로고
    • Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes
    • doi:10.1128/JVI.78.12.6122-6133.2004
    • Han, Y., et al. 2004. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J. Virol. 78:6122-6133. doi:10.1128/JVI.78.12.6122-6133.2004.
    • (2004) J. Virol. , vol.78 , pp. 122-6133
    • Han, Y.1
  • 20
    • 48649085472 scopus 로고    scopus 로고
    • Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough
    • doi:10.1016/j.chom.2008.06.008
    • Han, Y., et al. 2008. Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough. Cell Host Microbe 4:134-146. doi:10.1016/j.chom.2008.06.008.
    • (2008) Cell Host Microbe , vol.4 , pp. 34-146
    • Han, Y.1
  • 21
    • 0036232430 scopus 로고    scopus 로고
    • Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat
    • He, G., and D. M. Margolis. 2002. Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat. Mol. Cell. Biol. 22:2965-2973.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2965-2973
    • He, G.1    Margolis, D.M.2
  • 22
    • 0038468339 scopus 로고    scopus 로고
    • Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo
    • Hermankova, M., et al. 2003. Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo. J. Virol. 77:7383-7392.
    • (2003) J. Virol. , vol.77 , pp. 7383-7392
    • Hermankova, M.1
  • 23
    • 0028831057 scopus 로고
    • Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor
    • Herrmann, C. H., and A. P. Rice. 1995. Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor. J. Virol. 69:1612-1620.
    • (1995) J. Virol. , vol.69 , pp. 1612-1620
    • Herrmann, C.H.1    Rice, A.P.2
  • 24
    • 34948817683 scopus 로고    scopus 로고
    • Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes
    • doi:10.1038/nm1639
    • Huang, J., et al. 2007. Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes. Nat. Med. 13:1241-1247. doi:10.1038/nm1639.
    • (2007) Nat. Med. , vol.13 , pp. 241-1247
    • Huang, J.1
  • 25
    • 0028290825 scopus 로고
    • Control of RNA initiation and elongation at the HIV-1 promoter
    • doi: 10.1146/annurev.bi.63.070194.003441
    • Jones, K. A., and B. M. Peterlin. 1994. Control of RNA initiation and elongation at the HIV-1 promoter. Annu. Rev. Biochem. 63:717-743. doi: 10.1146/annurev.bi.63.070194.003441.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 17-743
    • Jones, K.A.1    Peterlin, B.M.2
  • 26
    • 55949083820 scopus 로고    scopus 로고
    • HIV rebounds from latently infected cells, rather than from continuing low-level replication
    • doi:10.1073/pnas.0804192105
    • Joos, B., et al. 2008. HIV rebounds from latently infected cells, rather than from continuing low-level replication. Proc. Natl. Acad. Sci. U. S. A. 105: 16725-16730. doi:10.1073/pnas.0804192105.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 6725-16730
    • Joos, B.1
  • 27
    • 0037446948 scopus 로고    scopus 로고
    • HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
    • doi:10.1093/emboj/cdg188
    • Jordan, A., D. Bisgrove, and E. Verdin. 2003. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. EMBO J. 22:1868-1877. doi:10.1093/emboj/cdg188.
    • (2003) EMBO J , vol.22 , pp. 868-1877
    • Jordan, A.1    Bisgrove, D.2    Verdin, E.3
  • 28
    • 0035794637 scopus 로고    scopus 로고
    • The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
    • doi:10.1093/emboj/20.7.1726
    • Jordan, A., P. Defechereux, and E. Verdin. 2001. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J. 20:1726-1738. doi:10.1093/emboj/20.7.1726.
    • (2001) EMBO J , vol.20 , pp. 726-1738
    • Jordan, A.1    Defechereux, P.2    Verdin, E.3
  • 29
    • 0023513563 scopus 로고
    • Antitermination of transcription within the long terminal repeat of HIV-1 by tat gene product
    • doi:10.1038/330489a0
    • Kao, S. Y., A. F. Calman, P. A. Luciw, and B. M. Peterlin. 1987. Antitermination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature 330:489-493. doi:10.1038/330489a0.
    • (1987) Nature , vol.330 , pp. 89-493
    • Kao, S.Y.1    Calman, A.F.2    Luciw, P.A.3    Peterlin, B.M.4
  • 30
    • 67650925025 scopus 로고    scopus 로고
    • Epigenetic regulation of HIV-1 latency by cytosine methylation
    • doi:10.1371/journal.ppat.1000495
    • Kauder, S. E., A. Bosque, A. Lindqvist, V. Planelles, and E. Verdin. 2009. Epigenetic regulation of HIV-1 latency by cytosine methylation. PLoS Pathog. 5:e1000495. doi:10.1371/journal.ppat.1000495.
    • (2009) PLoS Pathog , vol.5
    • Kauder, S.E.1    Bosque, A.2    Lindqvist, A.3    Planelles, V.4    Verdin, E.5
  • 31
    • 0030939152 scopus 로고    scopus 로고
    • The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells
    • Kinoshita, S., et al. 1997. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. Immunity 6:235-244.
    • (1997) Immunity , vol.6 , pp. 235-244
    • Kinoshita, S.1
  • 32
    • 7244255971 scopus 로고    scopus 로고
    • The multifactorial nature of HIV-1 latency
    • doi: 10.1016/j.molmed.2004.09.006
    • Lassen, K., Y. Han, Y. Zhou, J. Siliciano, and R. F. Siliciano. 2004. The multifactorial nature of HIV-1 latency. Trends Mol. Med. 10:525-531. doi: 10.1016/j.molmed.2004.09.006.
    • (2004) Trends Mol. Med. , vol.10 , pp. 525-531
    • Lassen, K.1    Han, Y.2    Zhou, Y.3    Siliciano, J.4    Siliciano, R.F.5
  • 33
    • 33746631821 scopus 로고    scopus 로고
    • Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells
    • doi:10.1371/journal.ppat.0020068
    • Lassen, K. G., K. X. Ramyar, J. R. Bailey, Y. Zhou, and R. F. Siliciano. 2006. Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells. PLoS Pathog. 2:e68. doi:10.1371/journal.ppat.0020068.
    • (2006) PLoS Pathog , vol.2
    • Lassen, K.G.1    Ramyar, K.X.2    Bailey, J.R.3    Zhou, Y.4    Siliciano, R.F.5
  • 34
    • 48649089113 scopus 로고    scopus 로고
    • Transcriptional interference antagonizes proviral gene expression to promote HIV latency
    • doi:10.1016/j.chom.2008.05.016
    • Lenasi, T., X. Contreras, and B. M. Peterlin. 2008. Transcriptional interference antagonizes proviral gene expression to promote HIV latency. Cell Host Microbe 4:123-133. doi:10.1016/j.chom.2008.05.016.
    • (2008) Cell Host Microbe , vol.4 , pp. 123-133
    • Lenasi, T.1    Contreras, X.2    Peterlin, B.M.3
  • 35
    • 21044451712 scopus 로고    scopus 로고
    • Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription
    • doi:10.1128/JVI.79.11.6610-6619.2005
    • Lewinski, M. K., et al. 2005. Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription. J. Virol. 79:6610-6619. doi:10.1128/JVI.79.11.6610-6619.2005.
    • (2005) J. Virol. , vol.79 , pp. 6610-6619
    • Lewinski, M.K.1
  • 36
    • 33746214675 scopus 로고    scopus 로고
    • Integration of human immunodeficiency virus type 1 in untreated infection occurs preferentially within genes
    • doi:10.1128/JVI.00542-06
    • Liu, H., et al. 2006. Integration of human immunodeficiency virus type 1 in untreated infection occurs preferentially within genes. J. Virol. 80:7765-7768. doi:10.1128/JVI.00542-06.
    • (2006) J. Virol. , vol.80 , pp. 7765-7768
    • Liu, H.1
  • 37
    • 71849085382 scopus 로고    scopus 로고
    • An in vitro system to model the establishment and reactivation of HIV-1 latency
    • Marini, A., J. M. Harper, and F. Romerio. 2008. An in vitro system to model the establishment and reactivation of HIV-1 latency. J. Immunol. 181:7713-7720.
    • (2008) J. Immunol. , vol.181 , pp. 7713-7720
    • Marini, A.1    Harper, J.M.2    Romerio, F.3
  • 38
    • 2942560254 scopus 로고    scopus 로고
    • Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene
    • doi:10.1038/nature02538
    • Martens, J. A., L. Laprade, and F. Winston. 2004. Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene. Nature 429: 571-574. doi:10.1038/nature02538.
    • (2004) Nature , vol.429 , pp. 571-574
    • Martens, J.A.1    Laprade, L.2    Winston, F.3
  • 39
    • 34548555700 scopus 로고    scopus 로고
    • Transcriptional interference: an unexpected layer of complexity in gene regulation
    • doi:10.1242/jcs.007633
    • Mazo, A., J. W. Hodgson, S. Petruk, Y. Sedkov, and H. W. Brock. 2007. Transcriptional interference: an unexpected layer of complexity in gene regulation. J. Cell Sci. 120:2755-2761. doi:10.1242/jcs.007633.
    • (2007) J. Cell Sci. , vol.120 , pp. 2755-2761
    • Mazo, A.1    Hodgson, J.W.2    Petruk, S.3    Sedkov, Y.4    Brock, H.W.5
  • 40
    • 0031686754 scopus 로고    scopus 로고
    • High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells
    • Mochizuki, H., J. P. Schwartz, K. Tanaka, R. O. Brady, and J. Reiser. 1998. High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells. J. Virol. 72:8873-8883.
    • (1998) J. Virol. , vol.72 , pp. 8873-8883
    • Mochizuki, H.1    Schwartz, J.P.2    Tanaka, K.3    Brady, R.O.4    Reiser, J.5
  • 41
    • 70349636603 scopus 로고    scopus 로고
    • Next-generation tag sequencing for cancer gene expression profiling
    • doi:10.1101/gr.094482.109
    • Morrissy, A. S., et al. 2009. Next-generation tag sequencing for cancer gene expression profiling. Genome Res. 19:1825-1835. doi:10.1101/gr.094482.109.
    • (2009) Genome Res , vol.19 , pp. 1825-1835
    • Morrissy, A.S.1
  • 42
    • 0023176085 scopus 로고
    • An inducible transcription factor activates expression of human immunodeficiency virus in T cells
    • doi:10.1038/326711a0
    • Nabel, G., and D. Baltimore. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326: 711-713. doi:10.1038/326711a0.
    • (1987) Nature , vol.326 , pp. 711-713
    • Nabel, G.1    Baltimore, D.2
  • 43
    • 0025328383 scopus 로고
    • Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latency
    • Pomerantz, R. J., D. Trono, M. B. Feinberg, and D. Baltimore. 1990. Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latency. Cell 61:1271-1276.
    • (1990) Cell , vol.61 , pp. 1271-1276
    • Pomerantz, R.J.1    Trono, D.2    Feinberg, M.B.3    Baltimore, D.4
  • 44
    • 0037173089 scopus 로고    scopus 로고
    • Transcriptional collision between convergent genes in budding yeast
    • doi:10. 1073/pnas.132270899
    • Prescott, E. M., and N. J. Proudfoot. 2002. Transcriptional collision between convergent genes in budding yeast. Proc. Natl. Acad. Sci. U. S. A. 99:8796-8801. doi:10.1073/pnas.132270899.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 8796-8801
    • Prescott, E.M.1    Proudfoot, N.J.2
  • 45
    • 33750608725 scopus 로고    scopus 로고
    • A novel in vitro system to generate and study latently HIV-infected long-lived normal CD4+ T-lymphocytes
    • doi:10.1016/j.virol.2006.07.020
    • Sahu, G. K., et al. 2006. A novel in vitro system to generate and study latently HIV-infected long-lived normal CD4+ T-lymphocytes. Virology 355:127-137. doi:10.1016/j.virol.2006.07.020.
    • (2006) Virology , vol.355 , pp. 127-137
    • Sahu, G.K.1
  • 46
    • 0037162715 scopus 로고    scopus 로고
    • HIV-1 integration in the human genome favors active genes and local hotspots
    • Schroder, A. R., et al. 2002. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110:521-529.
    • (2002) Cell , vol.110 , pp. 521-529
    • Schroder, A.R.1
  • 47
    • 0025039584 scopus 로고
    • Trans-activation by HIV-1 Tat via a heterologous RNA binding protein
    • Selby, M. J., and B. M. Peterlin. 1990. Trans-activation by HIV-1 Tat via a heterologous RNA binding protein. Cell 62:769-776.
    • (1990) Cell , vol.62 , pp. 769-776
    • Selby, M.J.1    Peterlin, B.M.2
  • 48
    • 19444377759 scopus 로고    scopus 로고
    • Transcriptional interference- a crash course
    • doi:101016/j. tig. 2005.04.009
    • Shearwin, K. E., B. P. Callen, and J. B. Egan. 2005. Transcriptional interference- a crash course. Trends Genet. 21:339-345. doi:10.1016/j.tig.2005.04.009.
    • (2005) Trends Genet , vol.21 , pp. 339-345
    • Shearwin, K.E.1    Callen, B.P.2    Egan, J.B.3
  • 49
    • 0038579210 scopus 로고    scopus 로고
    • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
    • doi:10.1038/nm880
    • Siliciano, J. D., et al. 2003. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat. Med. 9:727-728. doi:10.1038/nm880.
    • (2003) Nat. Med. , vol.9 , pp. 727-728
    • Siliciano, J.D.1
  • 50
    • 0242584383 scopus 로고    scopus 로고
    • Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence
    • doi:10.1073/pnas.0736332100
    • Strain, M. C., et al. 2003. Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proc. Natl. Acad. Sci. U. S. A. 100:4819-4824. doi:10.1073/pnas.0736332100.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 4819-4824
    • Strain, M.C.1
  • 51
    • 77953313393 scopus 로고    scopus 로고
    • Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction
    • doi:10.1128/JVI.01519-09
    • Tyagi, M., R. J. Pearson, and J. Karn. 2010. Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction. J. Virol. 84:6425-6437. doi:10.1128/JVI.01519-09.
    • (2010) J. Virol. , vol.84 , pp. 6425-6437
    • Tyagi, M.1    Pearson, R.J.2    Karn, J.3
  • 52
    • 0029919356 scopus 로고    scopus 로고
    • Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
    • Van Lint, C., S. Emiliani, M. Ott, and E. Verdin. 1996. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J. 15:1112-1120.
    • (1996) EMBO J , vol.15 , pp. 1112-1120
    • Van Lint, C.1    Emiliani, S.2    Ott, M.3    Verdin, E.4
  • 53
    • 66149094202 scopus 로고    scopus 로고
    • Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells
    • doi:10.1128/JVI.00356-09
    • Vatakis, D. N., S. Kim, N. Kim, S. A. Chow, and J. A. Zack. 2009. Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells. J. Virol. 83:6222-6233. doi:10.1128/JVI.00356-09.
    • (2009) J. Virol. , vol.83 , pp. 6222-6233
    • Vatakis, D.N.1    Kim, S.2    Kim, N.3    Chow, S.A.4    Zack, J.A.5
  • 55
    • 0027258123 scopus 로고
    • Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation
    • Verdin, E., P. Paras, Jr., and C. Van Lint. 1993. Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. EMBO J. 12:3249-3259.
    • (1993) EMBO J , vol.12 , pp. 3249-3259
    • Verdin, E.1    Paras Jr., P.2    Van Lint, C.3
  • 56
    • 33845657847 scopus 로고    scopus 로고
    • Understanding SAGE data
    • doi:10.1016/j.tig.2006.11.001
    • Wang, S. M. 2007. Understanding SAGE data. Trends Genet. 23:42-50. doi:10.1016/j.tig.2006.11.001.
    • (2007) Trends Genet , vol.23 , pp. 42-50
    • Wang, S.M.1
  • 57
    • 22744441386 scopus 로고    scopus 로고
    • Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
    • doi:10.1016/j.cell.2005.06.006
    • Weinberger, L. S., J. C. Burnett, J. E. Toettcher, A. P. Arkin, and D. V. Schaffer. 2005. Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell 122:169-182. doi:10.1016/j.cell.2005.06.006.
    • (2005) Cell , vol.122 , pp. 169-182
    • Weinberger, L.S.1    Burnett, J.C.2    Toettcher, J.E.3    Arkin, A.P.4    Schaffer, D.V.5
  • 58
    • 0034892960 scopus 로고    scopus 로고
    • Activation of human immunodeficiency virus transcription in T cells revisited: NF-kappaB p65 stimulates transcriptional elongation
    • West, M. J., A. D. Lowe, and J. Karn. 2001. Activation of human immunodeficiency virus transcription in T cells revisited: NF-kappaB p65 stimulates transcriptional elongation. J. Virol. 75:8524-8537.
    • (2001) J. Virol. , vol.75 , pp. 8524-8537
    • West, M.J.1    Lowe, A.D.2    Karn, J.3
  • 59
    • 30444431914 scopus 로고    scopus 로고
    • NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
    • doi:10.1038/sj.emboj.7600900
    • Williams, S. A., et al. 2006. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 25:139-149. doi:10.1038/sj.emboj.7600900.
    • (2006) EMBO J , vol.25 , pp. 139-149
    • Williams, S.A.1
  • 60
    • 34548849134 scopus 로고    scopus 로고
    • Regulation of HIV-1 latency by T-cell activation
    • doi:10.1016/j.cyto.2007.05.017
    • Williams, S. A., and W. C. Greene. 2007. Regulation of HIV-1 latency by T-cell activation. Cytokine 39:63-74. doi:10.1016/j.cyto.2007.05.017.
    • (2007) Cytokine , vol.39 , pp. 63-74
    • Williams, S.A.1    Greene, W.C.2
  • 61
    • 0030712305 scopus 로고    scopus 로고
    • Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
    • Wong, J. K., et al. 1997. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 278:1291-1295.
    • (1997) Science , vol.278 , pp. 1291-1295
    • Wong, J.K.1
  • 62
    • 70449377960 scopus 로고    scopus 로고
    • Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation
    • doi:10.1172/JCI39199
    • Yang, H. C., et al. 2009. Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. J. Clin. Invest. 119:3473-3486. doi:10.1172/JCI39199.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3473-3486
    • Yang, H.C.1
  • 63
    • 0033797161 scopus 로고    scopus 로고
    • Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy
    • doi:10.1172/JCI10565
    • Zhang, L., et al. 2000. Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy. J. Clin. Invest. 106:839-845. doi:10.1172/JCI10565.
    • (2000) J. Clin. Invest. , vol.106 , pp. 839-845
    • Zhang, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.