Changes in muscle proteomics in the course of the Caudwell Research Expedition to Mt. Everest

Proteomics

Volumn 15, Issue 1, 2015, Pages 160-171

  Levett, Denny Z H ^a,b   Viganò, Agnese ^c   Capitanio, Daniele ^c,d   Vasso, Michele ^e   De Palma, Sara ^e   Moriggi, Manuela ^c,d   Martin, Daniel S ^a   Murray, Andrew J ^f   Cerretelli, Paolo ^e   Grocott, Mike P W ^b,g,h   Gelfi, Cecilia ^c,d,e  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF MILAN   (Italy)

^d IRCCS POLICLINICO SAN DONATO   (Italy)

^e CNR   (Italy)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^g UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^h University Hospital Southampton NHS Foundation Trust   (United Kingdom)

Author keywords

Altitude hypoxia; Biomedicine; Ketoglutarate

Indexed keywords

2 OXOGLUTARIC ACID; CARBONATE DEHYDRATASE I; CATALASE; CREATINE KINASE; DJ 1 PROTEIN; FATTY ACID SYNTHASE; GLUTAMATE AMMONIA LIGASE; GLUTATHIONE SYNTHASE; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 70; ISOCITRATE DEHYDROGENASE 1; MYOSIN BINDING PROTEIN C; MYOSIN HEAVY CHAIN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PYRUVATE DEHYDROGENASE COMPLEX; SUCCINYL COENZYME A; VOLTAGE DEPENDENT ANION CHANNEL 1; VOLTAGE DEPENDENT ANION CHANNEL 2; ALPHA-KETOGLUTARIC ACID; MUSCLE PROTEIN;

ADULT; AEROBIC METABOLISM; ALTITUDE; ALTITUDE ACCLIMATIZATION; ALTITUDE DISEASE; ARTICLE; AUTOPHAGY; CALCIUM TRANSPORT; CHAPERONE-MEDIATED AUTOPHAGY; CITRIC ACID CYCLE; ENERGY EXPENDITURE; FATTY ACID METABOLISM; FEMALE; HUMAN; HUMAN EXPERIMENT; IMMUNOBLOTTING; MALE; MOUNTAINEERING; MUSCLE BIOPSY; NORMAL HUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; VASTUS LATERALIS MUSCLE; ACCLIMATIZATION; METABOLISM; PHYSIOLOGICAL STRESS; SKELETAL MUSCLE;

ACCLIMATIZATION; ADULT; ALTITUDE; FEMALE; HUMANS; KETOGLUTARIC ACIDS; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; PROTEOMICS; STRESS, PHYSIOLOGICAL;

EID: 84920628628     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201400306     Document Type: Article

References (47)

1. Kim, J. W., Tchernyshyov, I., Semenza, G. L., Dang, C. V., HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006, 3, 177-185.
2. Papandreou, I., Cairns, R. A., Fontana, L., Lim, A. L., Denko, N. C., HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006, 3, 187-197.
3. Sugden, M. C., Holness, M. J., Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases. Arch. Physiol. Biochem. 2006, 112, 139-149.
4. Bruick, R. K., McKnight, S. L., A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001, 294, 1337-1340.
5. Aragones, J., Schneider, M., Van Geyte, K., Fraisl, P. et al., Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat. Genet. 2008, 40, 170-180.
6. Miyata, T., Takizawa, S., van Ypersele de Strihou, C., Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets. Am. J. Physiol. Cell Physiol. 2011, 300, C226-C231.
7. Takeda, Y., Costa, S., Delamarre, E., Roncal, C. et al., Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature 2011, 479, 122-126.
8. Grocott, M., Montgomery, H., Vercueil, A., High-altitude physiology and pathophysiology: implications and relevance for intensive care medicine. Crit. Care 2007, 11, 203.
9. Hoppeler, H., Kleinert, E., Schlegel, C., Claassen, H. et al., Morphological adaptations of human skeletal muscle to chronic hypoxia. Int. J. Sports Med. 1990, 11(Suppl 1), S3-S9.
10. Howald, H., Pette, D., Simoneau, J. A., Uber, A. et al., Effect of chronic hypoxia on muscle enzyme activities. Int. J. Sports Med. 1990, 11(Suppl 1), S10-S14.
11. Gelfi, C., De Palma, S., Ripamonti, M., Eberini, I. et al., New aspects of altitude adaptation in Tibetans: a proteomic approach. FASEB J. 2004, 18, 612-614.
12. Robach, P., Cairo, G., Gelfi, C., Bernuzzi, F. et al., Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle. Blood 2007, 109, 4724-4731.
13. Vigano, A., Ripamonti, M., De Palma, S., Capitanio, D. et al., Proteins modulation in human skeletal muscle in the early phase of adaptation to hypobaric hypoxia. Proteomics 2008, 8, 4668-4679.
14. Levett, D. Z., Radford, E. J., Menassa, D. A., Graber, E. F. et al., Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest. FASEB J. 2012, 26, 1431-1441.
15. Jacobs, R. A., Boushel, R., Wright-Paradis, C., Calbet, J. A. et al., Mitochondrial function in human skeletal muscle following high-altitude exposure. Exp. Physiol. 2013, 98, 245-255.
16. Martin, D. S., Grocott, M. P., Oxygen therapy in critical illness: precise control of arterial oxygenation and permissive hypoxemia. Crit. Care Med. 2013, 41, 423-432.
17. Hoppeler, H., Vogt, M., Muscle tissue adaptations to hypoxia. J. Exp. Biol. 2001, 204, 3133-3139.
18. Vigano, A., Vasso, M., Caretti, A., Bravata, V. et al., Protein modulation in mouse heart under acute and chronic hypoxia. Proteomics 2011, 11, 4202-4217.
19. Levett, D. Z., Martin, D. S., Wilson, M. H., Mitchell, K. et al., Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia. BMC Med. Res. Methodol. 2010, 10, 98.
20. Danieli Betto, D., Zerbato, E., Betto, R., Type 1, 2A, and 2B myosin heavy chain electrophoretic analysis of rat muscle fibers. Biochem. Biophys. Res. Comm. 1986, 138, 981-987.
21. Taylor, C. F., Paton, N. W., Lilley, K. S., Binz, P. A. et al., The minimum information about a proteomics experiment (MIAPE). Nat. Biotechnol. 2007, 25, 887-893.
22. Karp, N. A., Lilley, K. S., Design and analysis issues in quantitative proteomics studies. Proteomics 2007, 7(Suppl 1), 42-50.
23. Capitanio, D., Vasso, M., Fania, C., Moriggi, M. et al., Comparative proteomic profile of rat sciatic nerve and gastrocnemius muscle tissues in ageing by 2-D DIGE. Proteomics 2009, 9, 2004-2020.
24. Camors, E., Monceau, V., Charlemagne, D., Annexins and Ca2+ handling in the heart. Cardiovasc. Res. 2005, 65, 793-802.
25. Arias, E., Cuervo, A. M., Chaperone-mediated autophagy in protein quality control. Curr. Opin. Cell Biol. 2011, 23, 184-189.
26. Yaguchi, T., Aida, S., Kaul, S. C., Wadhwa, R., Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions. Ann. NY Acad. Sci. 2007, 1100, 306-311.
27. Li, H. M., Niki, T., Taira, T., Iguchi-Ariga, S. M., Ariga, H., Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress. Free Radic. Res. 2005, 39, 1091-1099.
28. Zhang, H., Bosch-Marce, M., Shimoda, L. A., Tan, Y. S. et al., Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J. Biol. Chem. 2008, 283, 10892-10903.
29. Siddiq, A., Aminova, L. R., Ratan, R. R., Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress. Neurochem. Res. 2007, 32, 931-946.
30. Epstein, A. C., Gleadle, J. M., McNeill, L. A., Hewitson, K. S. et al., C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001, 107, 43-54.
31. Romero-Ruiz, A., Bautista, L., Navarro, V., Heras-Garvin, A. et al., Prolyl hydroxylase-dependent modulation of eukaryotic elongation factor 2 activity and protein translation under acute hypoxia. J. Biol. Chem. 2012, 287, 9651-9658.
32. Biolo, Muscle glutamine depletion in the intensive care unit. Int. J. Biochem. Cell Biol. 2005, 37, 2169-2179.
33. Rutten, E. P., Engelen, M. P., Schols, A. M., Deutz, N. E., Skeletal muscle glutamate metabolism in health and disease: state of the art. Curr. Opin. Clin. Nutr. Metab. Care 2005, 8, 41-51.
34. Hammarqvist, F., Wernerman, J., Ali, R., von der Decken, A., Vinnars, E., Addition of glutamine to total parenteral nutrition after elective abdominal surgery spares free glutamine in muscle, counteracts the fall in muscle protein synthesis, and improves nitrogen balance. Ann. Surg. 1989, 209, 455-461.
35. Yoo, H., Antoniewicz, M. R., Stephanopoulos, G., Kelleher, J. K., Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line. J. Biol. Chem. 2008, 283, 20621-20627.
36. Wise, D. R., Ward, P. S., Shay, J. E., Cross, J. R. et al., Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of alpha-ketoglutarate to citrate to support cell growth and viability. Proc. Natl. Acad. Sci. USA 2011, 108, 19611-19616.
37. Le, A., Lane, A. N., Hamaker, M., Bose, S. et al., Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metab. 2012, 15, 110-121.
38. Metallo, C. M., Gameiro, P. A., Bell, E. L., Mattaini, K. R. et al., Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature 2012, 481, 380-384.
39. Ferrer, C. M., Lynch, T. P., Sodi, V. L., Falcone, J. N. et al., O-GlcNacylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway. Mol. Cell 2014, 54, 820-831.
40. Oliveira, G. P., Dias, C. M., Pelosi, P., Rocco, P. R., Understanding the mechanisms of glutamine action in critically ill patients. An Acad. Bras Cienc. 2010, 82, 417-430.
41. Baranano, D. E., Rao, M., Ferris, C. D., Snyder, S. H., Biliverdin reductase: a major physiologic cytoprotectant. Proc. Natl. Acad. Sci. USA 2002, 99, 16093-16098.
42. Takashima, S., Phosphorylation of myosin regulatory light chain by myosin light chain kinase, and muscle contraction. Circ. J. 2009, 73, 208-213.
43. Rapizzi, E., Pinton, P., Szabadkai, G., Wieckowski, M. R. et al., Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2 +microdomains to mitochondria. J. Cell Biol. 2002, 159, 613-624.
44. Abu-Hamad, S., Sivan, S., Shoshan-Barmatz, V., The expression level of the voltage-dependent anion channel controls life and death of the cell. Proc. Natl. Acad. Sci. USA 2006, 103, 5787-5792.
45. De Stefani, D., Bononi, A., Romagnoli, A., Messina, A. et al., VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria. Cell Death Differ. 2012, 19, 267-273.
46. Rizzuto, R., De Stefani, D., Raffaello, A., Mammucari, C., Mitochondria as sensors and regulators of calcium signalling. Nat. Rev. Mol. Cell Biol. 2012, 13, 566-578.
47. De Palma, S., Leone, R., Grumati, P., Vasso, M. et al., Changes in muscle cell metabolism and mechanotransduction are associated with myopathic phenotype in a mouse model of collagen VI deficiency. PLoS One 2013, 8, e56716.