Gq-mediated Akt translocation to the membrane: A novel PIP3-independent mechanism in platelets

Blood

Volumn 125, Issue 1, 2015, Pages 175-184

  Badolia, Rachit ^a   Manne, Bhanu Kanth ^a   Dangelmaier, Carol ^a   Chernoff, Jonathan ^b   Kunapuli, Satya P ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

P21 ACTIVATED KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PURINERGIC P2Y RECEPTOR ANTAGONIST; PURINERGIC P2Y12 RECEPTOR ANTAGONIST; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; AKT1 PROTEIN, MOUSE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; POLYPHOSPHOINOSITIDE; THROMBIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STIMULATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NORMAL HUMAN; PROTEIN DEPLETION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL MEMBRANE; CYTOLOGY; METABOLISM; PHOSPHORYLATION; PROTEIN TRANSPORT; THROMBOCYTE; THROMBOCYTE AGGREGATION; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD PLATELETS; CELL MEMBRANE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MICE; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; PLATELET AGGREGATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; THROMBIN;

EID: 84920592539     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-05-576306     Document Type: Article

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