Protease-activated receptors 1 and 4 do not stimulate Gi signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of Gi signaling

Blood

Volumn 99, Issue 10, 2002, Pages 3629-3636

  Kim, Soochong ^a,b,c   Foster, Carolyn ^a,b,c   Lecchi, Anna ^a,b,c   Quinton, Todd M ^a,b,c   Prosser, Dina M ^a,b,c   Jin, Jianguo ^a,b,c   Cattaneo, Marco ^a,b,c   Kunapuli, Satya P ^a,b,c  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; ADENOSINE DIPHOSPHATE; ADENYLATE CYCLASE; FIBRINOGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; PEPTIDE; PROTEIN KINASE C INHIBITOR; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; THROMBIN; THROMBIN RECEPTOR; THROMBOXANE A2;

AGONIST; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HEMOSTASIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOSIS;

EID: 0037092952     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.10.3629     Document Type: Article

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