-
1
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
-
Haberland, M.; Montgomery, R.L.; Olson, E.N. The many roles of histone deacetylases in development and physiology: Implications for disease and therapy. Nat. Rev. Genet. 2009, 10, 32–42.
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
2
-
-
16844385708
-
Histone deacetylase-1 and -3 protein expression in human breast cancer: A tissue microarray analysis
-
Krusche, C.A.; Wulfing, P.; Kersting, C.; Vloet, A.; Bocker, W.; Kiesel, L.; Beier, H.M.; Alfer, J. Histone deacetylase-1 and -3 protein expression in human breast cancer: A tissue microarray analysis. Breast Cancer Res. Treat. 2005, 90, 15–23.
-
(2005)
Breast Cancer Res. Treat
, vol.90
, pp. 15-23
-
-
Krusche, C.A.1
Wulfing, P.2
Kersting, C.3
Vloet, A.4
Bocker, W.5
Kiesel, L.6
Beier, H.M.7
Alfer, J.8
-
3
-
-
41549159879
-
Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: Specific role of class I histone deacetylases in vitro and in vivo
-
Weichert, W.; Roske, A.; Niesporek, S.; Noske, A.; Buckendahl, A.C.; Dietel, M.; Gekeler, V.; Boehm, M.; Beckers, T.; Denkert, C. Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo. Clin. Cancer Res. 2008, 14, 1669–1677.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 1669-1677
-
-
Weichert, W.1
Roske, A.2
Niesporek, S.3
Noske, A.4
Buckendahl, A.C.5
Dietel, M.6
Gekeler, V.7
Boehm, M.8
Beckers, T.9
Denkert, C.10
-
4
-
-
79551521179
-
Disruption of a SIRT1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation
-
Powell, M.J.; Casimiro, M.C.; Cordon-Cardo, C.; He, X.; Yeow, W.S.; Wang, C.; McCue, P.A.; McBurney, M.W.; Pestell, R.G. Disruption of a SIRT1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Res. 2011, 71, 964–975.
-
(2011)
Cancer Res
, vol.71
, pp. 964-975
-
-
Powell, M.J.1
Casimiro, M.C.2
Cordon-Cardo, C.3
He, X.4
Yeow, W.S.5
Wang, C.6
McCue, P.A.7
McBurney, M.W.8
Pestell, R.G.9
-
5
-
-
58849158388
-
How does SIRT1 affect metabolism, senescence and cancer?
-
Brooks, C.L.; Gu, W. How does SIRT1 affect metabolism, senescence and cancer? Nat. Rev. Cancer 2009, 9, 123–128.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 123-128
-
-
Brooks, C.L.1
Gu, W.2
-
6
-
-
62449178216
-
The critical role of the class III histone deacetylase SIRT1 in cancer
-
Liu, T.; Liu, P.Y.; Marshall, G.M. The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res. 2009, 69, 1702–1705.
-
(2009)
Cancer Res
, vol.69
, pp. 1702-1705
-
-
Liu, T.1
Liu, P.Y.2
Marshall, G.M.3
-
7
-
-
67650348173
-
Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma
-
Cha, E.J.; Noh, S.J.; Kwon, K.S.; Kim, C.Y.; Park, B.H.; Park, H.S.; Lee, H.; Chung, M.J.; Kang, M.J.; Lee, D.G. et al. Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Clin. Cancer Res. 2009, 15, 4453–4459.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 4453-4459
-
-
Cha, E.J.1
Noh, S.J.2
Kwon, K.S.3
Kim, C.Y.4
Park, B.H.5
Park, H.S.6
Lee, H.7
Chung, M.J.8
Kang, M.J.9
Lee, D.G.10
-
8
-
-
78751567751
-
Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma
-
Lee, H.; Kim, K.R.; Noh, S.J.; Park, H.S.; Kwon, K.S.; Park, B.H.; Jung, S.H.; Youn, H.J.; Lee, B.K.; Chung, M.J. et al. Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma. Hum. Pathol. 2011, 42, 204–213.
-
(2011)
Hum. Pathol
, vol.42
, pp. 204-213
-
-
Lee, H.1
Kim, K.R.2
Noh, S.J.3
Park, H.S.4
Kwon, K.S.5
Park, B.H.6
Jung, S.H.7
Youn, H.J.8
Lee, B.K.9
Chung, M.J.10
-
9
-
-
84883336866
-
Expression of SIRT1 and DBC1 is associated with poor prognosis of soft tissue sarcomas
-
Kim, J.R.; Moon, Y.J.; Kwon, K.S.; Bae, J.S.; Wagle, S.; Yu, T.K.; Kim, K.M.; Park, H.S.; Lee, J.H.; Moon, W.S. et al. Expression of SIRT1 and DBC1 is associated with poor prognosis of soft tissue sarcomas. PLoS One 2013, 8, e74738.
-
(2013)
PLoS One
, vol.8
, pp. e74738
-
-
Kim, J.R.1
Moon, Y.J.2
Kwon, K.S.3
Bae, J.S.4
Wagle, S.5
Yu, T.K.6
Kim, K.M.7
Park, H.S.8
Lee, J.H.9
Moon, W.S.10
-
10
-
-
67650563916
-
SIRT1 is an inhibitor of proliferation and tumor formation in colon cancer
-
Kabra, N.; Li, Z.; Chen, L.; Li, B.; Zhang, X.; Wang, C.; Yeatman, T.; Coppola, D.; Chen, J. SIRT1 is an inhibitor of proliferation and tumor formation in colon cancer. J. Biol. Chem. 2009, 284, 18210–18217.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 18210-18217
-
-
Kabra, N.1
Li, Z.2
Chen, L.3
Li, B.4
Zhang, X.5
Wang, C.6
Yeatman, T.7
Coppola, D.8
Chen, J.9
-
11
-
-
84891361172
-
SIRT1 is downregulated in gastric cancer and leads to G1-phase arrest via NF-κB/Cyclin D1 signaling
-
Yang, Q.; Wang, B.; Gao, W.; Huang, S.; Liu, Z.; Li, W.; Jia, J. SIRT1 is downregulated in gastric cancer and leads to G1-phase arrest via NF-κB/Cyclin D1 signaling. Mol. Cancer Res. 2013, 11, 1497–1507.
-
(2013)
Mol. Cancer Res
, vol.11
, pp. 1497-1507
-
-
Yang, Q.1
Wang, B.2
Gao, W.3
Huang, S.4
Liu, Z.5
Li, W.6
Jia, J.7
-
12
-
-
84884764745
-
High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma
-
Stenzinger, A.; Endris, V.; Klauschen, F.; Sinn, B.; Lorenz, K.; Warth, A.; Goeppert, B.; Ehemann, V.; Muckenhuber, A.; Kamphues, C. et al. High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma. BMC. Cancer 2013, 13, 450.
-
(2013)
BMC. Cancer
, vol.13
, pp. 450
-
-
Stenzinger, A.1
Endris, V.2
Klauschen, F.3
Sinn, B.4
Lorenz, K.5
Warth, A.6
Goeppert, B.7
Ehemann, V.8
Muckenhuber, A.9
Kamphues, C.10
-
13
-
-
34547100073
-
SIRT1 is significantly elevated in mouse and human prostate cancer
-
Huffman, D.M.; Grizzle, W.E.; Bamman, M.M.; Kim, J.S.; Eltoum, I.A.; Elgavish, A.; Nagy, T.R. SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Res. 2007, 67, 6612–6618.
-
(2007)
Cancer Res
, vol.67
, pp. 6612-6618
-
-
Huffman, D.M.1
Grizzle, W.E.2
Bamman, M.M.3
Kim, J.S.4
Eltoum, I.A.5
Elgavish, A.6
Nagy, T.R.7
-
14
-
-
79958787784
-
Lai, P.B. et al. Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth
-
Chen, J.; Zhang, B.; Wong, N.; Lo, A.W.; To, K.F.; Chan, A.W.; Ng, M.H.; Ho, C.Y.; Cheng, S.H.; Lai, P.B. et al. Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth. Cancer Res. 2011, 71, 4138–4149.
-
(2011)
Cancer Res
, vol.71
, pp. 4138-4149
-
-
Chen, J.1
Zhang, B.2
Wong, N.3
Lo, A.W.4
To, K.F.5
Chan, A.W.6
Ng, M.H.7
Ho, C.Y.8
Cheng, S.H.9
-
15
-
-
84874538962
-
SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression
-
Holloway, K.R.; Barbieri, A.; Malyarchuk, S.; Saxena, M.; Nedeljkovic-Kurepa, A.; Cameron, M.M.; Wang, A.; Gu, X.; Pruitt, K. SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression. Mol. Endocrinol. 2013, 27, 480–490.
-
(2013)
Mol. Endocrinol
, vol.27
, pp. 480-490
-
-
Holloway, K.R.1
Barbieri, A.2
Malyarchuk, S.3
Saxena, M.4
Nedeljkovic-Kurepa, A.5
Cameron, M.M.6
Wang, A.7
Gu, X.8
Pruitt, K.9
-
16
-
-
77952714326
-
SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling
-
Holloway, K.R.; Calhoun, T.N.; Saxena, M.; Metoyer, C.F.; Kandler, E.F.; Rivera, C.A.; Pruitt, K. SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Proc. Natl. Acad. Sci. USA 2010, 107, 9216–9221.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 9216-9221
-
-
Holloway, K.R.1
Calhoun, T.N.2
Saxena, M.3
Metoyer, C.F.4
Kandler, E.F.5
Rivera, C.A.6
Pruitt, K.7
-
17
-
-
59649126261
-
Deacetylation of cortactin by SIRT1 promotes cell migration
-
Zhang, Y.; Zhang, M.; Dong, H.; Yong, S.; Li, X.; Olashaw, N.; Kruk, P.A.; Cheng, J.Q.; Bai, W.; Chen, J. et al. Deacetylation of cortactin by SIRT1 promotes cell migration. Oncogene 2008, 28, 445–460.
-
(2008)
Oncogene
, vol.28
, pp. 445-460
-
-
Zhang, Y.1
Zhang, M.2
Dong, H.3
Yong, S.4
Li, X.5
Olashaw, N.6
Kruk, P.A.7
Cheng, J.Q.8
Bai, W.9
Chen, J.10
-
18
-
-
84890448078
-
The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration
-
Saxena, M.; Dykes, S.S.; Malyarchuk, S.; Wang, A.E.; Cardelli, J.A.; Pruitt, K. The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration. Oncogene 2013, doi: 10.1038/onc.2013.549.
-
(2013)
Oncogene
-
-
Saxena, M.1
Dykes, S.S.2
Malyarchuk, S.3
Wang, A.E.4
Cardelli, J.A.5
Pruitt, K.6
-
19
-
-
84902525741
-
Frizzled 7 expression is positively regulated by SIRT1 and β-catenin in breast cancer cells
-
Simmons, G.E., Jr.; Pandey, S.; Nedeljkovic-Kurepa, A.; Saxena, M.; Wang, A.; Pruitt, K. Frizzled 7 expression is positively regulated by SIRT1 and β-catenin in breast cancer cells. PLoS One 2014, 9, e98861.
-
(2014)
PLoS One
, vol.9
, pp. e98861
-
-
Simmons, G.E.1
Pandey, S.2
Nedeljkovic-Kurepa, A.3
Saxena, M.4
Wang, A.5
Pruitt, K.6
-
20
-
-
33645768490
-
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
-
Pruitt, K.; Zinn, R.L.; Ohm, J.E.; McGarvey, K.M.; Kang, S.H.; Watkins, D.N.; Herman, J.G.; Baylin, S.B. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet. 2006, 2, e40.
-
(2006)
PLoS Genet
, vol.2
, pp. e40
-
-
Pruitt, K.1
Zinn, R.L.2
Ohm, J.E.3
McGarvey, K.M.4
Kang, S.H.5
Watkins, D.N.6
Herman, J.G.7
Baylin, S.B.8
-
21
-
-
52049102233
-
PTEN acetylation modulates its interaction with PDZ domain
-
Ikenoue, T.; Inoki, K.; Zhao, B.; Guan, K.L. PTEN acetylation modulates its interaction with PDZ domain. Cancer Res. 2008, 68, 6908–6912.
-
(2008)
Cancer Res
, vol.68
, pp. 6908-6912
-
-
Ikenoue, T.1
Inoki, K.2
Zhao, B.3
Guan, K.L.4
-
22
-
-
57349096045
-
The metabolic syndrome
-
Cornier, M.A.; Dabelea, D.; Hernandez, T.L.; Lindstrom, R.C.; Steig, A.J.; Stob, N.R.; van Pelt, R.E.; Wang, H.; Eckel, R.H. The metabolic syndrome. Endocr. Rev. 2008, 29, 777–822.
-
(2008)
Endocr. Rev
, vol.29
, pp. 777-822
-
-
Cornier, M.A.1
Dabelea, D.2
Hernandez, T.L.3
Lindstrom, R.C.4
Steig, A.J.5
Stob, N.R.6
Van Pelt, R.E.7
Wang, H.8
Eckel, R.H.9
-
23
-
-
84883706496
-
Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids
-
Zaidi, N.; Lupien, L.; Kuemmerle, N.B.; Kinlaw, W.B.; Swinnen, J.V.; Smans, K. Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids. Prog. Lipid Res. 2013, 52, 585–589.
-
(2013)
Prog. Lipid Res
, vol.52
, pp. 585-589
-
-
Zaidi, N.1
Lupien, L.2
Kuemmerle, N.B.3
Kinlaw, W.B.4
Swinnen, J.V.5
Smans, K.6
-
24
-
-
79960091939
-
Adipose triglyceride lipase contributes to cancer-associated cachexia
-
Das, S.K.; Eder, S.; Schauer, S.; Diwoky, C.; Temmel, H.; Guertl, B.; Gorkiewicz, G.; Tamilarasan, K.P.; Kumari, P.; Trauner, M. et al. Adipose triglyceride lipase contributes to cancer-associated cachexia. Science 2011, 333, 233–238.
-
(2011)
Science
, vol.333
, pp. 233-238
-
-
Das, S.K.1
Eder, S.2
Schauer, S.3
Diwoky, C.4
Temmel, H.5
Guertl, B.6
Gorkiewicz, G.7
Tamilarasan, K.P.8
Kumari, P.9
Trauner, M.10
-
25
-
-
84864646651
-
Cancer cachexia: Mediators, signaling, and metabolic pathways
-
Fearon, K.C.; Glass, D.J.; Guttridge, D.C. Cancer cachexia: Mediators, signaling, and metabolic pathways. Cell Metab. 2012, 16, 153–166.
-
(2012)
Cell Metab
, vol.16
, pp. 153-166
-
-
Fearon, K.C.1
Glass, D.J.2
Guttridge, D.C.3
-
26
-
-
84886899121
-
SIRT1 protein, by blocking the activities of transcription factors FOXO1 and FOXO3, inhibits muscle atrophy and promotes muscle growth
-
Lee, D.; Goldberg, A.L. SIRT1 protein, by blocking the activities of transcription factors FOXO1 and FOXO3, inhibits muscle atrophy and promotes muscle growth. J. Biol. Chem. 2013, 288, 30515–30526.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 30515-30526
-
-
Lee, D.1
Goldberg, A.L.2
-
27
-
-
16844379483
-
The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor γ and IκB kinase activities
-
Makowski, L.; Brittingham, K.C.; Reynolds, J.M.; Suttles, J.; Hotamisligil, G.S. The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor γ and IκB kinase activities. J. Biol. Chem. 2005, 280, 12888–12895.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 12888-12895
-
-
Makowski, L.1
Brittingham, K.C.2
Reynolds, J.M.3
Suttles, J.4
Hotamisligil, G.S.5
-
28
-
-
0034691282
-
Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions
-
Richieri, G.V.; Ogata, R.T.; Zimmerman, A.W.; Veerkamp, J.H.; Kleinfeld, A.M. Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. Biochemistry 2000, 39, 7197–7204.
-
(2000)
Biochemistry
, vol.39
, pp. 7197-7204
-
-
Richieri, G.V.1
Ogata, R.T.2
Zimmerman, A.W.3
Veerkamp, J.H.4
Kleinfeld, A.M.5
-
29
-
-
81255157465
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
-
Nieman, K.M.; Kenny, H.A.; Penicka, C.V.; Ladanyi, A.; Buell-Gutbrod, R.; Zillhardt, M.R.; Romero, I.L.; Carey, M.S.; Mills, G.B.; Hotamisligil, G.S. et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat. Med. 2011, 17, 1498–1503.
-
(2011)
Nat. Med
, vol.17
, pp. 1498-1503
-
-
Nieman, K.M.1
Kenny, H.A.2
Penicka, C.V.3
Ladanyi, A.4
Buell-Gutbrod, R.5
Zillhardt, M.R.6
Romero, I.L.7
Carey, M.S.8
Mills, G.B.9
Hotamisligil, G.S.10
-
30
-
-
84896728262
-
Expression of fatty acid binding protein 4 is involved in the cell growth of oral squamous cell carcinoma
-
Lee, D.; Wada, K.; Taniguchi, Y.; Al-Shareef, H.; Masuda, T.; Usami, Y.; Aikawa, T.; Okura, M.; Kamisaki, Y.; Kogo, M. Expression of fatty acid binding protein 4 is involved in the cell growth of oral squamous cell carcinoma. Oncol. Rep. 2014, 31, 1116–1120.
-
(2014)
Oncol. Rep
, vol.31
, pp. 1116-1120
-
-
Lee, D.1
Wada, K.2
Taniguchi, Y.3
Al-Shareef, H.4
Masuda, T.5
Usami, Y.6
Aikawa, T.7
Okura, M.8
Kamisaki, Y.9
Kogo, M.10
-
31
-
-
84921650957
-
Exogenous fatty acid binding protein 4 promotes human prostate cancer cell progression
-
Uehara, H.; Takahashi, T.; Oha, M.; Ogawa, H.; Izumi, K. Exogenous fatty acid binding protein 4 promotes human prostate cancer cell progression. Int. J. Cancer 2014, 135, 2558–2568.
-
(2014)
Int. J. Cancer
, vol.135
, pp. 2558-2568
-
-
Uehara, H.1
Takahashi, T.2
Oha, M.3
Ogawa, H.4
Izumi, K.5
-
32
-
-
77954488637
-
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
-
Walker, A.K.; Yang, F.; Jiang, K.; Ji, J.Y.; Watts, J.L.; Purushotham, A.; Boss, O.; Hirsch, M.L.; Ribich, S.; Smith, J.J. et al. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010, 24, 1403–1417.
-
(2010)
Genes Dev
, vol.24
, pp. 1403-1417
-
-
Walker, A.K.1
Yang, F.2
Jiang, K.3
Ji, J.Y.4
Watts, J.L.5
Purushotham, A.6
Boss, O.7
Hirsch, M.L.8
Ribich, S.9
Smith, J.J.10
-
33
-
-
33751113602
-
Mammalian sirtuin—Emerging roles in physiology, aging, and calorie restriction
-
Haigis, M.C.; Guarente, L.P. Mammalian sirtuin—Emerging roles in physiology, aging, and calorie restriction. Genes Dev. 2006, 20, 2913–2921.
-
(2006)
Genes Dev
, vol.20
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
34
-
-
49549105992
-
Low Sirt1 expression, which is up-regulated by fasting, in human adipose tissue from obese women
-
Pedersen, S.B.; Olholm, J.; Paulsen, S.K.; Bennetzen, M.F.; Richelsen, B. Low Sirt1 expression, which is up-regulated by fasting, in human adipose tissue from obese women. Int. J. Obes. 2008, 32, 1250–1255.
-
(2008)
Int. J. Obes
, vol.32
, pp. 1250-1255
-
-
Pedersen, S.B.1
Olholm, J.2
Paulsen, S.K.3
Bennetzen, M.F.4
Richelsen, B.5
-
35
-
-
50649112638
-
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
-
Hou, X.; Xu, S.; Maitland-Toolan, K.A.; Sato, K.; Jiang, B.; Ido, Y.; Lan, F.; Walsh, K.; Wierzbicki, M.; Verbeuren, T.J. et al. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J. Biol. Chem. 2008, 283, 20015–20026.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 20015-20026
-
-
Hou, X.1
Xu, S.2
Maitland-Toolan, K.A.3
Sato, K.4
Jiang, B.5
Ido, Y.6
Lan, F.7
Walsh, K.8
Wierzbicki, M.9
Verbeuren, T.J.10
-
36
-
-
63449127032
-
Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores
-
Zechner, R.; Kienesberger, P.C.; Haemmerle, G.; Zimmermann, R.; Lass, A. Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. J. Lipid Res. 2009, 50, 3–21.
-
(2009)
J. Lipid Res
, vol.50
, pp. 3-21
-
-
Zechner, R.1
Kienesberger, P.C.2
Haemmerle, G.3
Zimmermann, R.4
Lass, A.5
-
37
-
-
80051826470
-
SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL
-
Chakrabarti, P.; English, T.; Karki, S.; Qiang, L.; Tao, R.; Kim, J.; Luo, Z.; Farmer, S.R.; Kandror, K.V. SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL. J. Lipid Res. 2011, 52, 1693–1701.
-
(2011)
J. Lipid Res
, vol.52
, pp. 1693-1701
-
-
Chakrabarti, P.1
English, T.2
Karki, S.3
Qiang, L.4
Tao, R.5
Kim, J.6
Luo, Z.7
Farmer, S.R.8
Kandror, K.V.9
-
38
-
-
51849147067
-
Role of FOXO1 activation in MDR1 expression in adriamycin-resistant breast cancer cells
-
Han, C.Y.; Cho, K.B.; Choi, H.S.; Han, H.K.; Kang, K.W. Role of FOXO1 activation in MDR1 expression in adriamycin-resistant breast cancer cells. Carcinogenesis 2008, 29, 1837–1844.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1837-1844
-
-
Han, C.Y.1
Cho, K.B.2
Choi, H.S.3
Han, H.K.4
Kang, K.W.5
-
39
-
-
20144365700
-
Nuclear trapping of the forkhead transcription factor FOXO1 via SIRT-dependent deacetylation promotes expression of glucogenetic genes
-
Frescas, D.; Valenti, L.; Accili, D. Nuclear trapping of the forkhead transcription factor FOXO1 via SIRT-dependent deacetylation promotes expression of glucogenetic genes. J. Biol. Chem. 2005, 280, 20589–20595.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 20589-20595
-
-
Frescas, D.1
Valenti, L.2
Accili, D.3
-
40
-
-
84879701384
-
SIRT1-mediated FOXO1 deacetylation is essential for multidrug resistance-associated protein 2 expression in tamoxifen-resistant breast cancer cells
-
Choi, H.K.; Cho, K.B.; Phuong, N.T.; Han, C.Y.; Han, H.K.; Hien, T.T.; Choi, H.S.; Kang, K.W. SIRT1-mediated FOXO1 deacetylation is essential for multidrug resistance-associated protein 2 expression in tamoxifen-resistant breast cancer cells. Mol. Pharm. 2013, 10, 2517–2527.
-
(2013)
Mol. Pharm
, vol.10
, pp. 2517-2527
-
-
Choi, H.K.1
Cho, K.B.2
Phuong, N.T.3
Han, C.Y.4
Han, H.K.5
Hien, T.T.6
Choi, H.S.7
Kang, K.W.8
-
41
-
-
84903748283
-
The forkhead transcription factor FOXO1 mediates cisplatin resistance in gastric cancer cells by activating phosphoinositide 3-kinase/Akt pathway
-
Park, J.; Ko, Y.S.; Yoon, J.; Kim, M.A.; Park, J.W.; Kim, W.H.; Choi, Y.; Kim, J.H.; Cheon, Y.; Lee, B.L. The forkhead transcription factor FOXO1 mediates cisplatin resistance in gastric cancer cells by activating phosphoinositide 3-kinase/Akt pathway. Gastric Cancer 2014, 17, 423–430.
-
(2014)
Gastric Cancer
, vol.17
, pp. 423-430
-
-
Park, J.1
Ko, Y.S.2
Yoon, J.3
Kim, M.A.4
Park, J.W.5
Kim, W.H.6
Choi, Y.7
Kim, J.H.8
Cheon, Y.9
Lee, B.L.10
-
42
-
-
84901193863
-
Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor
-
Wang, X.; Lin, C.; Zhao, X.; Liu, A.; Zhu, J.; Li, X.; Song, L. Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor. Mol. Cancer 2014, 13, 106.
-
(2014)
Mol. Cancer
, vol.13
, pp. 106
-
-
Wang, X.1
Lin, C.2
Zhao, X.3
Liu, A.4
Zhu, J.5
Li, X.6
Song, L.7
-
43
-
-
16344384026
-
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
-
Yang, Y.; Hou, H., Haller, E.M.; Nicosia, S.V.; Bai, W. Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO J. 2005, 24, 1021–1032.
-
(2005)
EMBO J
, vol.24
, pp. 1021-1032
-
-
Yang, Y.1
Hou, H.2
Haller, E.M.3
Nicosia, S.V.4
Bai, W.5
-
44
-
-
3042750643
-
Silent information regulator 2 potentiates FOXO1-mediated transcription through its deacetylase activity
-
Daitoku, H.; Hatta, M.; Matsuzaki, H.; Aratani, S.; Ohshima, T.; Miyagishi, M.; Nakajima, T.; Fukamizu, A. Silent information regulator 2 potentiates FOXO1-mediated transcription through its deacetylase activity. Proc. Natl. Acad. Sci. USA 2004, 101, 10042–10047.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
Aratani, S.4
Ohshima, T.5
Miyagishi, M.6
Nakajima, T.7
Fukamizu, A.8
-
45
-
-
84886928680
-
FOXO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes
-
Singh, B.K.; Sinha, R.A.; Zhou, J.; Xie, S.Y.; You, S.H.; Gauthier, K.; Yen, P.M. FOXO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes. J. Biol. Chem. 2013, 288, 30365–30372.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 30365-30372
-
-
Singh, B.K.1
Sinha, R.A.2
Zhou, J.3
Xie, S.Y.4
You, S.H.5
Gauthier, K.6
Yen, P.M.7
-
46
-
-
84872296122
-
Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone
-
Thakran, S.; Sharma, P.; Attia, R.R.; Hori, R.T.; Deng, X.; Elam, M.B.; Park, E.A. Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone. J. Biol. Chem. 2013, 288, 807–818.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 807-818
-
-
Thakran, S.1
Sharma, P.2
Attia, R.R.3
Hori, R.T.4
Deng, X.5
Elam, M.B.6
Park, E.A.7
-
47
-
-
14844282050
-
Regulation of PPAR-γ activity during adipogenesis
-
Farmer, S.R. Regulation of PPAR-γ activity during adipogenesis. Int. J. Obes. 2005, 29, S13–S16.
-
(2005)
Int. J. Obes
, vol.29
, pp. S13-S16
-
-
Farmer, S.R.1
-
48
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz, P.; Hu, E.; Spiegelman, B.M. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 1994, 79, 1147–1156.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
49
-
-
0033213637
-
Evans, R.M. PPAR-γ is required for placental, cardiac, and adipose tissue development
-
Barak, Y.; Nelson, M.C.; Ong, E.S.; Jones, Y.Z.; Ruiz-Lozano, P.; Chien, K.R.; Koder, A.; Evans, R.M. PPAR-γ is required for placental, cardiac, and adipose tissue development. Mol. Cell 1999, 4, 585–595.
-
(1999)
Mol. Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
-
50
-
-
0028129499
-
Ectopic expression of the CCAAT/enhancer-binding protein α promotes the adipogenic program in a variety of mouse fibroblastic cells
-
Freytag, S.O.; Paielli, D.L.; Gilbert, J.D. Ectopic expression of the CCAAT/enhancer-binding protein α promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev. 1994, 8, 1654–1663.
-
(1994)
Genes Dev
, vol.8
, pp. 1654-1663
-
-
Freytag, S.O.1
Paielli, D.L.2
Gilbert, J.D.3
-
51
-
-
84907501117
-
Acetylation-defective mutant of PPAR-γ is associated with decreased lipid synthesis in breast cancer cells
-
Tian, L.; Wang, C.; Hagen, F.K.; Gormley, M.; Addya, S.; Soccio, R.; Casimiro, M.C.; Zhou, J.; Powell, M.J.; Xu, P. et al. Acetylation-defective mutant of PPAR-γ is associated with decreased lipid synthesis in breast cancer cells. Oncotarget 2014, 5, 7303–7315.
-
(2014)
Oncotarget
, vol.5
, pp. 7303-7315
-
-
Tian, L.1
Wang, C.2
Hagen, F.K.3
Gormley, M.4
Addya, S.5
Soccio, R.6
Casimiro, M.C.7
Zhou, J.8
Powell, M.J.9
Xu, P.10
-
52
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin, J.; Handschin, C.; Spiegelman, B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 2005, 1, 361–370.
-
(2005)
Cell Metab
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
53
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
Uldry, M.; Yang, W.; St-Pierre, J.; Lin, J.; Seale, P.; Spiegelman, B.M. Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab. 2006, 3, 333–341.
-
(2006)
Cell Metab
, vol.3
, pp. 333-341
-
-
Uldry, M.1
Yang, W.2
St-Pierre, J.3
Lin, J.4
Seale, P.5
Spiegelman, B.M.6
-
54
-
-
2942724616
-
Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise
-
Pilegaard, H.; Neufer, P.D. Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise. Proc. Nutr. Soc. 2004, 63, 221–226.
-
(2004)
Proc. Nutr. Soc
, vol.63
, pp. 221-226
-
-
Pilegaard, H.1
Neufer, P.D.2
-
55
-
-
3042681042
-
SIRT1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
-
Picard, F.; Kurtev, M.; Chung, N.; Topark-Ngarm, A.; Senawong, T.; de Oliveira, R.M.; Leid, M.; McBurney, M.W.; Guarente, L. SIRT1 promotes fat mobilization in white adipocytes by repressing PPAR-γ. Nature 2004, 429, 771–776.
-
(2004)
Nature
, vol.429
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
De Oliveira, R.M.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
56
-
-
75149194039
-
PPAR control: It’s SIRTainly as easy as PGC
-
Sugden, M.C.; Caton, P.W.; Holness, M.J. PPAR control: It’s SIRTainly as easy as PGC. J. Endocrinol. 2010, 204, 93–104.
-
(2010)
J. Endocrinol
, vol.204
, pp. 93-104
-
-
Sugden, M.C.1
Caton, P.W.2
Holness, M.J.3
-
57
-
-
47749128879
-
SIRT1 protects against high-fat diet-induced metabolic damage
-
Pfluger, P.T.; Herranz, D.; Velasco-Miguel, S.; Serrano, M.; Tschop, M.H. SIRT1 protects against high-fat diet-induced metabolic damage. Proc. Natl. Acad. Sci. USA 2008, 105, 9793–9798.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 9793-9798
-
-
Pfluger, P.T.1
Herranz, D.2
Velasco-Miguel, S.3
Serrano, M.4
Tschop, M.H.5
-
58
-
-
63449112017
-
Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
-
Purushotham, A.; Schug, T.T.; Xu, Q.; Surapureddi, S.; Guo, X.; Li, X. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab. 2009, 9, 327–338.
-
(2009)
Cell Metab
, vol.9
, pp. 327-338
-
-
Purushotham, A.1
Schug, T.T.2
Xu, Q.3
Surapureddi, S.4
Guo, X.5
Li, X.6
-
59
-
-
77954515012
-
Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: A role of lipid mobilization and inflammation
-
Xu, F.; Gao, Z.; Zhang, J.; Rivera, C.A.; Yin, J.; Weng, J.; Ye, J. Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: A role of lipid mobilization and inflammation. Endocrinology 2010, 151, 2504–2514.
-
(2010)
Endocrinology
, vol.151
, pp. 2504-2514
-
-
Xu, F.1
Gao, Z.2
Zhang, J.3
Rivera, C.A.4
Yin, J.5
Weng, J.6
Ye, J.7
-
60
-
-
55549096745
-
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
-
Lan, F.; Cacicedo, J.M.; Ruderman, N.; Ido, Y. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. J. Biol. Chem. 2008, 283, 27628–27635.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 27628-27635
-
-
Lan, F.1
Cacicedo, J.M.2
Ruderman, N.3
Ido, Y.4
-
61
-
-
0033032546
-
Effects of retigabine (D-23129) on different patterns of epileptiform activity induced by 4-aminopyridine in rat entorhinal cortex hippocampal slices
-
Armand, V.; Rundfeldt, C.; Heinemann, U. Effects of retigabine (D-23129) on different patterns of epileptiform activity induced by 4-aminopyridine in rat entorhinal cortex hippocampal slices. Naunyn-Schmiedebergs Arch. Pharmacol. 1999, 359, 33–39.
-
(1999)
Naunyn-Schmiedebergs Arch. Pharmacol
, vol.359
, pp. 33-39
-
-
Armand, V.1
Rundfeldt, C.2
Heinemann, U.3
-
62
-
-
10044271037
-
SREBP transcription factors: Master regulators of lipid homeostasis
-
Eberle, D.; Hegarty, B.; Bossard, P.; Ferre, P.; Foufelle, F. SREBP transcription factors: Master regulators of lipid homeostasis. Biochimie 2004, 86, 839–848.
-
(2004)
Biochimie
, vol.86
, pp. 839-848
-
-
Eberle, D.1
Hegarty, B.2
Bossard, P.3
Ferre, P.4
Foufelle, F.5
-
63
-
-
0142027805
-
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
-
Horton, J.D.; Shah, N.A.; Warrington, J.A.; Anderson, N.N.; Park, S.W.; Brown, M.S.; Goldstein, J.L. Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes. Proc. Natl. Acad. Sci. USA 2003, 100, 12027–12032.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12027-12032
-
-
Horton, J.D.1
Shah, N.A.2
Warrington, J.A.3
Anderson, N.N.4
Park, S.W.5
Brown, M.S.6
Goldstein, J.L.7
-
64
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
Shimano, H.; Horton, J.D.; Hammer, R.E.; Shimomura, I.; Brown, M.S.; Goldstein, J.L. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J. Clin. Investig. 1996, 98, 1575–1584.
-
(1996)
J. Clin. Investig
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
Horton, J.D.2
Hammer, R.E.3
Shimomura, I.4
Brown, M.S.5
Goldstein, J.L.6
-
65
-
-
28444434745
-
Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease
-
Jiang, T.; Liebman, S.E.; Lucia, M.S.; Phillips, C.L.; Levi, M. Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease. J. Am. Soc. Nephrol. 2005, 16, 2385–2394.
-
(2005)
J. Am. Soc. Nephrol
, vol.16
, pp. 2385-2394
-
-
Jiang, T.1
Liebman, S.E.2
Lucia, M.S.3
Phillips, C.L.4
Levi, M.5
-
66
-
-
0030911517
-
Cleavage site for sterol-regulated protease localized to a Leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2
-
Duncan, E.A.; Brown, M.S.; Goldstein, J.L.; Sakai, J. Cleavage site for sterol-regulated protease localized to a Leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2. J. Biol. Chem. 1997, 272, 12778–12785.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 12778-12785
-
-
Duncan, E.A.1
Brown, M.S.2
Goldstein, J.L.3
Sakai, J.4
-
67
-
-
0028225462
-
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
-
Wang, X.; Sato, R.; Brown, M.S.; Hua, X.; Goldstein, J.L. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 1994, 77, 53–62.
-
(1994)
Cell
, vol.77
, pp. 53-62
-
-
Wang, X.1
Sato, R.2
Brown, M.S.3
Hua, X.4
Goldstein, J.L.5
-
68
-
-
0017136701
-
Peripherally and centrally mediated bradycardiac effects of clonidine in anesthetized or spinal rats
-
Ozawa, H.; Uematsu, T. Peripherally and centrally mediated bradycardiac effects of clonidine in anesthetized or spinal rats. Tohoku J. Exp. Med. 1976, 119, 283–291.
-
(1976)
Tohoku J. Exp. Med
, vol.119
, pp. 283-291
-
-
Ozawa, H.1
Uematsu, T.2
-
69
-
-
0037378516
-
Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors
-
Giandomenico, V.; Simonsson, M.; Gronroos, E.; Ericsson, J. Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors. Mol. Cell. Biol. 2003, 23, 2587–2599.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 2587-2599
-
-
Giandomenico, V.1
Simonsson, M.2
Gronroos, E.3
Ericsson, J.4
-
70
-
-
77958595135
-
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism
-
Ponugoti, B.; Kim, D.H.; Xiao, Z.; Smith, Z.; Miao, J.; Zang, M.; Wu, S.Y.; Chiang, C.M.; Veenstra, T.D.; Kemper, J.K. SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism. J. Biol. Chem. 2010, 285, 33959–33970.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 33959-33970
-
-
Ponugoti, B.1
Kim, D.H.2
Xiao, Z.3
Smith, Z.4
Miao, J.5
Zang, M.6
Wu, S.Y.7
Chiang, C.M.8
Veenstra, T.D.9
Kemper, J.K.10
-
71
-
-
81055127044
-
SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2
-
Hirschey, M.D.; Shimazu, T.; Capra, J.A.; Pollard, K.S.; Verdin, E. SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2. Aging 2011, 3, 635–642.
-
(2011)
Aging
, vol.3
, pp. 635-642
-
-
Hirschey, M.D.1
Shimazu, T.2
Capra, J.A.3
Pollard, K.S.4
Verdin, E.5
-
72
-
-
84870380514
-
Aromatase inhibitors for the treatment of endometriosis
-
Pavone, M.E.; Bulun, S.E. Aromatase inhibitors for the treatment of endometriosis. Fertil. Steril. 2012, 98, 1370–1379.
-
(2012)
Fertil. Steril
, vol.98
, pp. 1370-1379
-
-
Pavone, M.E.1
Bulun, S.E.2
-
73
-
-
0242499440
-
Aromatase inhibitors for breast cancer: Lessons from the laboratory
-
Johnston, S.R.; Dowsett, M. Aromatase inhibitors for breast cancer: lessons from the laboratory. Nat. Rev. Cancer 2003, 3, 821–831.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 821-831
-
-
Johnston, S.R.1
Dowsett, M.2
-
74
-
-
77955551055
-
American Society of Clinical Oncology clinical practice guideline: Update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer
-
Burstein, H.J.; Prestrud, A.A.; Seidenfeld, J.; Anderson, H.; Buchholz, T.A.; Davidson, N.E.; Gelmon, K.E.; Giordano, S.H.; Hudis, C.A.; Malin, J. et al. American Society of Clinical Oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer. J. Clin. Oncol. 2010, 28, 3784–3796.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 3784-3796
-
-
Burstein, H.J.1
Prestrud, A.A.2
Seidenfeld, J.3
Anderson, H.4
Buchholz, T.A.5
Davidson, N.E.6
Gelmon, K.E.7
Giordano, S.H.8
Hudis, C.A.9
Malin, J.10
-
75
-
-
30944469849
-
Estrogen carcinogenesis in breast cancer
-
Yager, J.D.; Davidson, N.E. Estrogen carcinogenesis in breast cancer. N. Engl. J. Med. 2006, 354, 270–282.
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 270-282
-
-
Yager, J.D.1
Davidson, N.E.2
-
76
-
-
84887092638
-
Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells
-
Wang, J.; Gildea, J.J.; Yue, W. Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells. Oncogene 2012, 32, 5233–5240.
-
(2012)
Oncogene
, vol.32
, pp. 5233-5240
-
-
Wang, J.1
Gildea, J.J.2
Yue, W.3
-
77
-
-
0034016224
-
Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues
-
Chetrite, G.S.; Cortes-Prieto, J.; Philippe, J.C.; Wright, F.; Pasqualini, J.R. Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues. J. Steroid Biochem. Mol. Biol. 2000, 72, 23–27.
-
(2000)
J. Steroid Biochem. Mol. Biol
, vol.72
, pp. 23-27
-
-
Chetrite, G.S.1
Cortes-Prieto, J.2
Philippe, J.C.3
Wright, F.4
Pasqualini, J.R.5
-
78
-
-
0034177586
-
A novel HPLC-RIA method for the simultaneous detection of estrone, estradiol and estrone sulphate levels in breast cancer tissue
-
Geisler, J.; Berntsen, H.; Lonning, P.E. A novel HPLC-RIA method for the simultaneous detection of estrone, estradiol and estrone sulphate levels in breast cancer tissue. J. Steroid Biochem. Mol. Biol. 2000, 72, 259–264.
-
(2000)
J. Steroid Biochem. Mol. Biol
, vol.72
, pp. 259-264
-
-
Geisler, J.1
Berntsen, H.2
Lonning, P.E.3
-
79
-
-
0021931084
-
Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue
-
Van Landeghem, A.A.; Poortman, J.; Nabuurs, M.; Thijssen, J.H. Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue. Cancer Res. 1985, 45, 2900–2906.
-
(1985)
Cancer Res
, vol.45
, pp. 2900-2906
-
-
Van Landeghem, A.A.1
Poortman, J.2
Nabuurs, M.3
Thijssen, J.H.4
-
80
-
-
11444264897
-
Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women
-
Missmer, S.A.; Eliassen, A.H.; Barbieri, R.L.; Hankinson, S.E. Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women. J. Natl. Cancer Inst. 2004, 96, 1856–1865.
-
(2004)
J. Natl. Cancer Inst
, vol.96
, pp. 1856-1865
-
-
Missmer, S.A.1
Eliassen, A.H.2
Barbieri, R.L.3
Hankinson, S.E.4
-
81
-
-
29144464971
-
Postmenopausal serum androgens, oestrogens and breast cancer risk: The European prospective investigation into cancer and nutrition
-
Kaaks, R.; Rinaldi, S.; Key, T.J.; Berrino, F.; Peeters, P.H.; Biessy, C.; Dossus, L.; Lukanova, A.; Bingham, S.; Khaw, K.T. et al. Postmenopausal serum androgens, oestrogens and breast cancer risk: The European prospective investigation into cancer and nutrition. Endocr. Relat. Cancer 2005, 12, 1071–1082.
-
(2005)
Endocr. Relat. Cancer
, vol.12
, pp. 1071-1082
-
-
Kaaks, R.1
Rinaldi, S.2
Key, T.J.3
Berrino, F.4
Peeters, P.H.5
Biessy, C.6
Dossus, L.7
Lukanova, A.8
Bingham, S.9
Khaw, K.T.10
-
82
-
-
80052034915
-
Circulating sex hormones and breast cancer risk factors in postmenopausal women: Reanalysis of 13 studies
-
Key, T.J.; Appleby, P.N.; Reeves, G.K.; Roddam, A.W.; Helzlsouer, K.J.; Alberg, A.J.; Rollison, D.E.; Dorgan, J.F.; Brinton, L.A.; Overvad, K. et al. Circulating sex hormones and breast cancer risk factors in postmenopausal women: Reanalysis of 13 studies. Br. J. Cancer 2011, 105, 709–722.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 709-722
-
-
Key, T.J.1
Appleby, P.N.2
Reeves, G.K.3
Roddam, A.W.4
Helzlsouer, K.J.5
Alberg, A.J.6
Rollison, D.E.7
Dorgan, J.F.8
Brinton, L.A.9
Overvad, K.10
-
83
-
-
70349770785
-
Rapid estradiol/ERα signaling enhances aromatase enzymatic activity in breast cancer cells
-
Catalano, S.; Barone, I.; Giordano, C.; Rizza, P.; Qi, H.; Gu, G.; Malivindi, R.; Bonofiglio, D.; Ando, S. Rapid estradiol/ERα signaling enhances aromatase enzymatic activity in breast cancer cells. Mol. Endocrinol. 2009, 23, 1634–1645.
-
(2009)
Mol. Endocrinol
, vol.23
, pp. 1634-1645
-
-
Catalano, S.1
Barone, I.2
Giordano, C.3
Rizza, P.4
Qi, H.5
Gu, G.6
Malivindi, R.7
Bonofiglio, D.8
Ando, S.9
-
84
-
-
77956999983
-
Bocchinfuso,W. et al. Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms
-
Yue, W.; Wang, J.P.; Li, Y.; Fan, P.; Liu, G.; Zhang, N.; Conaway, M.; Wang, H.; Korach, K.S.; Bocchinfuso,W. et al. Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms. Int. J. Cancer 2010, 127, 1748–1757.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 1748-1757
-
-
Yue, W.1
Wang, J.P.2
Li, Y.3
Fan, P.4
Liu, G.5
Zhang, N.6
Conaway, M.7
Wang, H.8
Korach, K.S.9
-
85
-
-
48349112953
-
The role of sirtuin proteins in obesity
-
Metoyer, C.F.; Pruitt, K. The role of sirtuin proteins in obesity. Pathophysiology 2008, 15, 103–108.
-
(2008)
Pathophysiology
, vol.15
, pp. 103-108
-
-
Metoyer, C.F.1
Pruitt, K.2
-
86
-
-
33644511694
-
Of mice and men: The evolving phenotype of aromatase deficiency
-
Jones, M.E.; Boon, W.C.; Proietto, J.; Simpson, E.R. Of mice and men: The evolving phenotype of aromatase deficiency. Trends Endocrinol. Metab. 2006, 17, 55–64.
-
(2006)
Trends Endocrinol. Metab
, vol.17
, pp. 55-64
-
-
Jones, M.E.1
Boon, W.C.2
Proietto, J.3
Simpson, E.R.4
-
87
-
-
0035498544
-
Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma
-
Bonneterre, J.; Buzdar, A.; Nabholtz, J.M.; Robertson, J.F.R.; Thurlimann, B.; von Euler, M.; Sahmoud, T.; Webster, A.; Steinberg, M. Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma. Cancer 2001, 92, 2247–2258.
-
(2001)
Cancer
, vol.92
, pp. 2247-2258
-
-
Bonneterre, J.1
Buzdar, A.2
Nabholtz, J.M.3
Robertson, J.F.R.4
Thurlimann, B.5
Von Euler, M.6
Sahmoud, T.7
Webster, A.8
Steinberg, M.9
|