Oral delivery of capsaicin using MPEG-PCL nanoparticles

Acta Pharmacologica Sinica

Volumn 36, Issue 1, 2015, Pages 139-148

  Peng, Wei ^a   Jiang, Xin Yi ^a   Zhu, Yuan ^a   Omari Siaw, E ^a   Deng, Wen Wen ^a   Yu, Jiang Nan ^a   Xu, Xi Ming ^a   Zhang, Wei Ming ^b  

^a JIANGSU UNIVERSITY   (China)

^b Nanjing Institute for Comprehensive Utilization of Wild Plants ^*  (China)

Author keywords

capsaicin; gastric mucosa irritation; MPEG PCL; nanoparticles; pharmacokinetics

Indexed keywords

BIOPOLYMER; CAPSAICIN; COPOLYMER; HEMATOXYLIN; NANOCARRIER; POLY(ETHYLENE GLYCOL) POLY(EPSILON CAPROLACTONE)NANOPARTICLE; UNCLASSIFIED DRUG; DRUG CARRIER; MACROGOL DERIVATIVE; METHOXY POLY(ETHYLENE GLYCOL-CO-EPSILON-CAPROLACTONE); NANOPARTICLE; POLYESTER;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; DIALYSIS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; IN VITRO STUDY; INFRARED SPECTROSCOPY; MALE; MAXIMUM PLASMA CONCENTRATION; NANOEMULSION; NANOPHARMACEUTICS; NONHUMAN; PARTICLE SIZE; RAT; STAINING; STOMACH MUCOSA; SUSPENSION; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION; ANIMAL; CHEMISTRY; ORAL DRUG ADMINISTRATION; PROCEDURES; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; CAPSAICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; MALE; NANOPARTICLES; POLYESTERS; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84920418911     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2014.113     Document Type: Article

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