Robust PEGylated hyaluronic acid nanoparticles as the carrier of doxorubicin: Mineralization and its effect on tumor targetability in vivo

Journal of Controlled Release

Volumn 168, Issue 2, 2013, Pages 105-114

  Han, Hwa Seung ^a   Lee, Jungmin ^b   Kim, Hyun Ryoung ^b   Chae, Su Young ^b   Kim, Minwoo ^b   Saravanakumar, Gurusamy ^a   Yoon, Hong Yeol ^a,c   You, Dong Gil ^a,c   Ko, Hyewon ^a   Kim, Kwangmeyung ^c   Kwon, Ick Chan ^c   Park, Jae Chan ^b   Park, Jae Hyung ^a  

^a Sungkyunkwan University   (South Korea)

^b Samsung Advanced Institute of Technology (SAIT)   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

Doxorubicin; Hyaluronic acid; Mineralization; Nanoparticles; Stability

Indexed keywords

ANTI-TUMOR EFFICACY; CONTROLLED DEPOSITION; DOXORUBICIN; MINERALIZATION; PHYSIOLOGICAL CONDITION; POLYMERIC NANOPARTICLES; SEQUENTIAL ADDITION; SYSTEMIC ADMINISTRATION;

CONVERGENCE OF NUMERICAL METHODS; DRUG DELIVERY; HYALURONIC ACID; MINERALOGY; ORGANIC ACIDS; POLYETHYLENE GLYCOLS; TUMORS;

NANOPARTICLES;

DOXORUBICIN; HYALURONIC ACID; MACROGOL; NANOCARRIER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG RELEASE; DRUG STABILITY; FREEZE DRYING; HYDRODYNAMICS; IN VIVO STUDY; MINERALIZATION; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; ZETA POTENTIAL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CALCIUM PHOSPHATES; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; HYALURONIC ACID; MICE; MICE, NUDE; NANOPARTICLES; NEOPLASMS; POLYETHYLENE GLYCOLS; TISSUE DISTRIBUTION; TUMOR BURDEN;

EID: 84876190170     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.02.022     Document Type: Article

References (28)

1. A. Harada, and K. Kataoka Supramolecular assemblies of block copolymers in aqueous media as nanocontainers relevant to biological applications Prog. Polym. Sci. 31 2006 949 982
2. M.E. Davis, Z. Chen, and D.M. Shin Nanoparticle therapeutics: an emerging treatment modality for cancer Nat. Rev. Drug Discov. 7 2008 771 782
3. J.H. Park, S. Lee, J.-H. Kim, K. Park, K. Kim, and I.C. Kwon Polymeric nanomedicine for cancer therapy Prog. Polym. Sci. 33 2008 113 137
4. Y.H. Bae, and H. Yin Stability issues of polymeric micelles J. Control. Release 131 2008 2 4
5. S.C. Owen, D.P.Y. Chan, and M.S. Shoichet Polymeric micelle stability Nano Today 7 2012 53 65
6. R.K. O'Reilly, C.J. Hawker, and K.L. Wooley Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility Chem. Soc. Rev. 35 2006 1068 1083
7. E.S. Read, and S.P. Armes Recent advances in shell cross-linked micelles Chem. Commun. 2007 3021 3035
8. K.B. Thurmond, T. Kowalewski, and K.L. Wooley Water-soluble knedel-like structures: the preparation of shell-cross-linked small particles J. Am. Chem. Soc. 118 1996 7239 7240
9. H.J. Lee, S.E. Kim, I.K. Kwon, C. Park, C. Kim, J. Yang, and S.C. Lee Spatially mineralized self-assembled polymeric nanocarriers with enhanced robustness and controlled drug-releasing property Chem. Commun. (Camb.) 46 2010 377 379
10. K.K. Perkin, J.L. Turner, K.L. Wooley, and S. Mann Fabrication of hybrid nanocapsules by calcium phosphate mineralization of shell cross-linked polymer micelles and nanocages Nano Lett. 5 2005 1457 1461
11. Y.L. Li, W.J. Du, G.R. Sun, and K.L. Wooley pH-responsive shell cross-linked nanoparticles with hydrolytically labile cross-links Macromolecules 41 2008 6605 6607
12. A.N. Koo, H.J. Lee, S.E. Kim, J.H. Chang, C. Park, C. Kim, J.H. Park, and S.C. Lee Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery Chem. Commun. 2008 6570 6572
13. Q. Huo, J. Liu, L.-Q. Wang, Y. Jiang, T.N. Lambert, and E. Fang A new class of silica cross-linked micellar core-shell nanoparticles J. Am. Chem. Soc. 128 2006 6447 6453
14. K. Subburaman, N. Pernodet, S.Y. Kwak, E. DiMasi, S. Ge, V. Zaitsev, X. Ba, N.L. Yang, and M. Rafailovich Templated biomineralization on self-assembled protein fibers Proc. Natl. Acad. Sci. U.S.A. 103 2006 14672 14677
15. K. Engin, D.B. Leeper, J.R. Cater, A.J. Thistlethwaite, L. Tupchong, and J.D. McFarlane Extracellular pH distribution in human tumours Int. J. Hyperthermia 11 1995 211 216
16. V.M. Platt, and F.C. Szoka Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor Mol. Pharm. 5 2008 474 486
17. K.Y. Choi, G. Saravanakumar, J.H. Park, and K. Park Hyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer Colloids Surf. B: Biointerfaces 99 2012 82 94
18. B.P. Toole Hyaluronan: from extracellular glue to pericellular cue Nat. Rev. Cancer 4 2004 528 539
19. K.Y. Choi, H. Chung, K.H. Min, H.Y. Yoon, K. Kim, J.H. Park, I.C. Kwon, and S.Y. Jeong Self-assembled hyaluronic acid nanoparticles for active tumor targeting Biomaterials 31 2010 106 114
20. K.Y. Choi, K.H. Min, J.H. Na, K. Choi, K. Kim, J.H. Park, I.C. Kwon, and S.Y. Jeong Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: synthesis, characterization, and in vivo biodistribution J. Mater. Chem. 19 2009 4102 4107
21. G. Saravanakumar, K.Y. Choi, H.Y. Yoon, K. Kim, J.H. Park, I.C. Kwon, and K. Park Hydrotropic hyaluronic acid conjugates: synthesis, characterization, and implications as a carrier of paclitaxel Int. J. Pharm. 394 2010 154 161
22. B. Zhou, J.A. Weigel, L. Fauss, and P.H. Weigel Identification of the hyaluronan receptor for endocytosis (HARE) J. Biol. Chem. 275 2000 37733 37741
23. K.Y. Choi, K.H. Min, H.Y. Yoon, K. Kim, J.H. Park, I.C. Kwon, K. Choi, and S.Y. Jeong PEGylation of hyaluronic acid nanoparticles improves tumor targetability in vivo Biomaterials 32 2011 1880 1889
24. S.-Y. Han, H.S. Han, S.C. Lee, Y.M. Kang, I.-S. Kim, and J.H. Park Mineralized hyaluronic acid nanoparticles as a robust drug carrier J. Mater. Chem. 21 2011 7996 8001
25. K.Y. Choi, H.Y. Yoon, J.-H. Kim, S.M. Bae, R.-W. Park, Y.M. Kang, I.-S. Kim, I.C. Kwon, K. Choi, S.Y. Jeong, K. Kim, and J.H. Park Smart nanocarrier based on PEGylated hyaluronic acid for cancer therapy ACS Nano 5 2011 8591 8599
26. H.T. Schmidt, and A.E. Ostafin Liposome directed growth of calcium phosphate nanoshells Adv. Mater. 14 2002 532 535
27. J. Ko, K. Park, Y.S. Kim, M.S. Kim, J.K. Han, K. Kim, R.W. Park, I.S. Kim, H.K. Song, D.S. Lee, and I.C. Kwon Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly(beta-amino ester) block copolymer micelles for cancer therapy J. Control. Release 123 2007 109 115
28. D. Gewirtz A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin Biochem. Pharmacol. 57 1999 727 741