-
1
-
-
80054781460
-
Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-d-aspartate receptor subunit-selective modulators
-
Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC & Traynelis SF (2011). Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-d-aspartate receptor subunit-selective modulators. Mol Pharmacol 80, 782-795.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 782-795
-
-
Acker, T.M.1
Yuan, H.2
Hansen, K.B.3
Vance, K.M.4
Ogden, K.K.5
Jensen, H.S.6
Burger, P.B.7
Mullasseril, P.8
Snyder, J.P.9
Liotta, D.C.10
Traynelis, S.F.11
-
2
-
-
0033636314
-
Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core
-
Armstrong N & Gouaux E (2000). Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron 28, 165-181.
-
(2000)
Neuron
, vol.28
, pp. 165-181
-
-
Armstrong, N.1
Gouaux, E.2
-
3
-
-
33749059766
-
Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor
-
Armstrong N, Jasti J, Beich-Frandsen M & Gouaux E (2006). Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor. Cell 127, 85-97.
-
(2006)
Cell
, vol.127
, pp. 85-97
-
-
Armstrong, N.1
Jasti, J.2
Beich-Frandsen, M.3
Gouaux, E.4
-
4
-
-
84874626300
-
Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters
-
Assaf Z, Larsen AP, Venskutonyte R, Han L, Abrahamsen B, Nielsen B, Gajhede M, Kastrup JS, Jensen AA, Pickering DS, Frydenvang K, Gefflaut T & Bunch L (2013). Chemoenzymatic synthesis of new 2, 4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters. J Med Chem 56, 1614-1628.
-
(2013)
J Med Chem
, vol.56
, pp. 1614-1628
-
-
Assaf, Z.1
Larsen, A.P.2
Venskutonyte, R.3
Han, L.4
Abrahamsen, B.5
Nielsen, B.6
Gajhede, M.7
Kastrup, J.S.8
Jensen, A.A.9
Pickering, D.S.10
Frydenvang, K.11
Gefflaut, T.12
Bunch, L.13
-
5
-
-
26944451291
-
Molecular mechanism of AMPA receptor noncompetitive antagonism
-
Balannik V, Menniti FS, Paternain AV, Lerma J & Stern-Bach Y (2005). Molecular mechanism of AMPA receptor noncompetitive antagonism. Neuron 48, 279-288.
-
(2005)
Neuron
, vol.48
, pp. 279-288
-
-
Balannik, V.1
Menniti, F.S.2
Paternain, A.V.3
Lerma, J.4
Stern-Bach, Y.5
-
6
-
-
84881232191
-
α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and N-methyl-d-aspartate (NMDA) receptors adopt different subunit arrangements
-
Balasuriya D, Goetze TA, Barrera NP, Stewart AP, Suzuki Y & Edwardson JM (2013). α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and N-methyl-d-aspartate (NMDA) receptors adopt different subunit arrangements. J Biol Chem 288, 21987-21998.
-
(2013)
J Biol Chem
, vol.288
, pp. 21987-21998
-
-
Balasuriya, D.1
Goetze, T.A.2
Barrera, N.P.3
Stewart, A.P.4
Suzuki, Y.5
Edwardson, J.M.6
-
7
-
-
48849113877
-
Ionotropic glutamate receptors & CNS disorders
-
Bowie D (2008). Ionotropic glutamate receptors & CNS disorders. CNS Neurol Disord Drug Targets 7, 129-143.
-
(2008)
CNS Neurol Disord Drug Targets
, vol.7
, pp. 129-143
-
-
Bowie, D.1
-
8
-
-
73549084285
-
Ion-dependent gating of kainate receptors
-
Bowie D (2010). Ion-dependent gating of kainate receptors. J Physiol 588, 67-81.
-
(2010)
J Physiol
, vol.588
, pp. 67-81
-
-
Bowie, D.1
-
9
-
-
68149092677
-
Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions
-
Chaudhry C, Plested AJ, Schuck P & Mayer ML (2009a). Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions. Proc Natl Acad Sci U S A 106, 12329-12334.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12329-12334
-
-
Chaudhry, C.1
Plested, A.J.2
Schuck, P.3
Mayer, M.L.4
-
10
-
-
67349279392
-
Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization
-
Chaudhry C, Weston MC, Schuck P, Rosenmund C & Mayer ML (2009b). Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. EMBO J 28, 1518-1530.
-
(2009)
EMBO J
, vol.28
, pp. 1518-1530
-
-
Chaudhry, C.1
Weston, M.C.2
Schuck, P.3
Rosenmund, C.4
Mayer, M.L.5
-
11
-
-
84866562579
-
Dancing partners at the synapse: auxiliary subunits that shape kainate receptor function
-
Copits BA & Swanson GT (2012). Dancing partners at the synapse: auxiliary subunits that shape kainate receptor function. Nat Rev Neurosci 13, 675-686.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 675-686
-
-
Copits, B.A.1
Swanson, G.T.2
-
12
-
-
84881617618
-
Crosslinking the ligand-binding domain dimer interface locks kainate receptors out of the main open state
-
Daniels BA, Andrews ED, Aurousseau MR, Accardi MV & Bowie D (2013). Crosslinking the ligand-binding domain dimer interface locks kainate receptors out of the main open state. J Physiol 591, 3873-3885.
-
(2013)
J Physiol
, vol.591
, pp. 3873-3885
-
-
Daniels, B.A.1
Andrews, E.D.2
Aurousseau, M.R.3
Accardi, M.V.4
Bowie, D.5
-
13
-
-
77952362034
-
Domain organization and function in GluK2 subtype kainate receptors
-
Das U, Kumar J, Mayer ML & Plested AJ (2010). Domain organization and function in GluK2 subtype kainate receptors. Proc Natl Acad Sci U S A 107, 8463-8468.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 8463-8468
-
-
Das, U.1
Kumar, J.2
Mayer, M.L.3
Plested, A.J.4
-
14
-
-
84883743072
-
Defining the structural relationship between kainate-receptor deactivation and desensitization
-
Dawe GB, Musgaard M, Andrews ED, Daniels BA, Aurousseau MR, Biggin PC & Bowie D (2013). Defining the structural relationship between kainate-receptor deactivation and desensitization. Nat Struct Mol Biol 20, 1054-1061.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 1054-1061
-
-
Dawe, G.B.1
Musgaard, M.2
Andrews, E.D.3
Daniels, B.A.4
Aurousseau, M.R.5
Biggin, P.C.6
Bowie, D.7
-
15
-
-
84855166359
-
Structure and function of glutamate receptor amino terminal domains
-
Furukawa H (2012). Structure and function of glutamate receptor amino terminal domains. J Physiol 590, 63-72.
-
(2012)
J Physiol
, vol.590
, pp. 63-72
-
-
Furukawa, H.1
-
16
-
-
27744500994
-
Subunit arrangement and function in NMDA receptors
-
Furukawa H, Singh SK, Mancusso R & Gouaux E (2005). Subunit arrangement and function in NMDA receptors. Nature 438, 185-192.
-
(2005)
Nature
, vol.438
, pp. 185-192
-
-
Furukawa, H.1
Singh, S.K.2
Mancusso, R.3
Gouaux, E.4
-
17
-
-
77953103088
-
Role of dimer interface in activation and desensitization in AMPA receptors
-
Gonzalez J, Du M, Parameshwaran K, Suppiramaniam V & Jayaraman V (2010). Role of dimer interface in activation and desensitization in AMPA receptors. Proc Natl Acad Sci U S A 107, 9891-9896.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 9891-9896
-
-
Gonzalez, J.1
Du, M.2
Parameshwaran, K.3
Suppiramaniam, V.4
Jayaraman, V.5
-
18
-
-
77957235696
-
Control of assembly and function of glutamate receptors by the amino-terminal domain
-
Hansen KB, Furukawa H & Traynelis SF (2010). Control of assembly and function of glutamate receptors by the amino-terminal domain. Mol Pharmacol 78, 535-549.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 535-549
-
-
Hansen, K.B.1
Furukawa, H.2
Traynelis, S.F.3
-
19
-
-
59649125327
-
Modulation of the dimer interface at ionotropic glutamate-like receptor δ2 by d-serine and extracellular calcium
-
Hansen KB, Naur P, Kurtkaya NL, Kristensen AS, Gajhede M, Kastrup JS & Traynelis SF (2009). Modulation of the dimer interface at ionotropic glutamate-like receptor δ2 by d-serine and extracellular calcium. J Neurosci 29, 907-917.
-
(2009)
J Neurosci
, vol.29
, pp. 907-917
-
-
Hansen, K.B.1
Naur, P.2
Kurtkaya, N.L.3
Kristensen, A.S.4
Gajhede, M.5
Kastrup, J.S.6
Traynelis, S.F.7
-
20
-
-
79952411415
-
Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D-containing NMDA receptors
-
Hansen KB & Traynelis SF (2011). Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D-containing NMDA receptors. J Neurosci 31, 3650-3661.
-
(2011)
J Neurosci
, vol.31
, pp. 3650-3661
-
-
Hansen, K.B.1
Traynelis, S.F.2
-
21
-
-
84866382191
-
Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy
-
Harms JE, Benveniste M, Maclean JK, Partin KM & Jamieson C (2013). Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology 64, 45-52.
-
(2013)
Neuropharmacology
, vol.64
, pp. 45-52
-
-
Harms, J.E.1
Benveniste, M.2
Maclean, J.K.3
Partin, K.M.4
Jamieson, C.5
-
22
-
-
0028596211
-
N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1
-
Hollmann M, Maron C & Heinemann S (1994). N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1. Neuron 13, 1331-1343.
-
(1994)
Neuron
, vol.13
, pp. 1331-1343
-
-
Hollmann, M.1
Maron, C.2
Heinemann, S.3
-
23
-
-
67649565613
-
Crystal structure and association behaviour of the GluR2 amino-terminal domain
-
Jin R, Singh SK, Gu S, Furukawa H, Sobolevsky AI, Zhou J, Jin Y & Gouaux E (2009). Crystal structure and association behaviour of the GluR2 amino-terminal domain. EMBO J 28, 1812-1823.
-
(2009)
EMBO J
, vol.28
, pp. 1812-1823
-
-
Jin, R.1
Singh, S.K.2
Gu, S.3
Furukawa, H.4
Sobolevsky, A.I.5
Zhou, J.6
Jin, Y.7
Gouaux, E.8
-
24
-
-
72449151659
-
Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit
-
Karakas E, Simorowski N & Furukawa H (2009). Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. EMBO J 28, 3910-3920.
-
(2009)
EMBO J
, vol.28
, pp. 3910-3920
-
-
Karakas, E.1
Simorowski, N.2
Furukawa, H.3
-
25
-
-
79960417429
-
Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors
-
Karakas E, Simorowski N & Furukawa H (2011). Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature 475, 249-253.
-
(2011)
Nature
, vol.475
, pp. 249-253
-
-
Karakas, E.1
Simorowski, N.2
Furukawa, H.3
-
26
-
-
14644420979
-
The Uppsala Electron-Density Server
-
Kleywegt GJ, Harris MR, Zou JY, Taylor TC, Wahlby A & Jones TA (2004). The Uppsala Electron-Density Server. Acta Crystallogr D Biol Crystallogr 60, 2240-2249.
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 2240-2249
-
-
Kleywegt, G.J.1
Harris, M.R.2
Zou, J.Y.3
Taylor, T.C.4
Wahlby, A.5
Jones, T.A.6
-
27
-
-
34548232365
-
Inference of macromolecular assemblies from crystalline state
-
Krissinel E & Henrick K (2007). Inference of macromolecular assemblies from crystalline state. J Mol Biol 372, 774-797.
-
(2007)
J Mol Biol
, vol.372
, pp. 774-797
-
-
Krissinel, E.1
Henrick, K.2
-
28
-
-
84873681332
-
Functional insights from glutamate receptor ion channel structures
-
Kumar J & Mayer ML (2013). Functional insights from glutamate receptor ion channel structures. Annu Rev Physiol 75, 313-337.
-
(2013)
Annu Rev Physiol
, vol.75
, pp. 313-337
-
-
Kumar, J.1
Mayer, M.L.2
-
29
-
-
67349285101
-
The N-terminal domain of GluR6-subtype glutamate receptor ion channels
-
Kumar J, Schuck P, Jin R & Mayer ML (2009). The N-terminal domain of GluR6-subtype glutamate receptor ion channels. Nat Struct Mol Biol 16, 631-638.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 631-638
-
-
Kumar, J.1
Schuck, P.2
Jin, R.3
Mayer, M.L.4
-
30
-
-
79960652046
-
Structure and assembly mechanism for heteromeric kainate receptors
-
Kumar J, Schuck P & Mayer ML (2011). Structure and assembly mechanism for heteromeric kainate receptors. Neuron 71, 319-331.
-
(2011)
Neuron
, vol.71
, pp. 319-331
-
-
Kumar, J.1
Schuck, P.2
Mayer, M.L.3
-
31
-
-
79955525364
-
Amino terminal domains of the NMDA receptor are organized as local heterodimers
-
Lee CH & Gouaux E (2011). Amino terminal domains of the NMDA receptor are organized as local heterodimers. PLoS One 6, e19180.
-
(2011)
PLoS One
, vol.6
, pp. e19180
-
-
Lee, C.H.1
Gouaux, E.2
-
33
-
-
0035819074
-
Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement
-
Mansour M, Nagarajan N, Nehring RB, Clements JD & Rosenmund C (2001). Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement. Neuron 32, 841-853.
-
(2001)
Neuron
, vol.32
, pp. 841-853
-
-
Mansour, M.1
Nagarajan, N.2
Nehring, R.B.3
Clements, J.D.4
Rosenmund, C.5
-
34
-
-
84856790671
-
Domain architecture of a calcium-permeable AMPA receptor in a ligand-free conformation
-
Midgett CR, Gill A & Madden DR (2012). Domain architecture of a calcium-permeable AMPA receptor in a ligand-free conformation. Front Mol Neurosci 4, 56.
-
(2012)
Front Mol Neurosci
, vol.4
, pp. 56
-
-
Midgett, C.R.1
Gill, A.2
Madden, D.R.3
-
35
-
-
45849133048
-
Regulation of AMPA receptor gating and pharmacology by TARP auxiliary subunits
-
Milstein AD & Nicoll RA (2008). Regulation of AMPA receptor gating and pharmacology by TARP auxiliary subunits. Trends Pharmacol Sci 29, 333-339.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 333-339
-
-
Milstein, A.D.1
Nicoll, R.A.2
-
36
-
-
79961020657
-
Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines
-
Mony L, Zhu S, Carvalho S & Paoletti P (2011). Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. EMBO J 30, 3134-3146.
-
(2011)
EMBO J
, vol.30
, pp. 3134-3146
-
-
Mony, L.1
Zhu, S.2
Carvalho, S.3
Paoletti, P.4
-
37
-
-
35348840286
-
Ionotropic glutamate-like receptor δ2 binds d-serine and glycine
-
Naur P, Hansen KB, Kristensen AS, Dravid SM, Pickering DS, Olsen L, Vestergaard B, Egebjerg J, Gajhede M, Traynelis SF & Kastrup JS (2007). Ionotropic glutamate-like receptor δ2 binds d-serine and glycine. Proc Natl Acad Sci U S A 104, 14116-14121.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14116-14121
-
-
Naur, P.1
Hansen, K.B.2
Kristensen, A.S.3
Dravid, S.M.4
Pickering, D.S.5
Olsen, L.6
Vestergaard, B.7
Egebjerg, J.8
Gajhede, M.9
Traynelis, S.F.10
Kastrup, J.S.11
-
38
-
-
79951985476
-
Conformational flexibility of the ligand-binding domain dimer in kainate receptor gating and desensitization
-
Nayeem N, Mayans O & Green T (2011). Conformational flexibility of the ligand-binding domain dimer in kainate receptor gating and desensitization. J Neurosci 31, 2916-2924.
-
(2011)
J Neurosci
, vol.31
, pp. 2916-2924
-
-
Nayeem, N.1
Mayans, O.2
Green, T.3
-
39
-
-
84897364740
-
Correlating efficacy and desensitization with GluK2 ligand-binding domain movements
-
Nayeem N, Mayans O & Green T (2013). Correlating efficacy and desensitization with GluK2 ligand-binding domain movements. Open Biol 3, 130051.
-
(2013)
Open Biol
, vol.3
, pp. 130051
-
-
Nayeem, N.1
Mayans, O.2
Green, T.3
-
40
-
-
69549120617
-
A non-desensitizing kainate receptor point mutant
-
Nayeem N, Zhang Y, Schweppe DK, Madden DR & Green T (2009). A non-desensitizing kainate receptor point mutant. Mol Pharmacol 76, 534-542.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 534-542
-
-
Nayeem, N.1
Zhang, Y.2
Schweppe, D.K.3
Madden, D.R.4
Green, T.5
-
41
-
-
79954630544
-
Molecular basis of NMDA receptor functional diversity
-
Paoletti P (2011). Molecular basis of NMDA receptor functional diversity. Eur J Neurosci 33, 1351-1365.
-
(2011)
Eur J Neurosci
, vol.33
, pp. 1351-1365
-
-
Paoletti, P.1
-
42
-
-
33846920665
-
NMDA receptor subunits: function and pharmacology
-
Paoletti P & Neyton J (2007). NMDA receptor subunits: function and pharmacology. Curr Opin Pharmacol 7, 39-47.
-
(2007)
Curr Opin Pharmacol
, vol.7
, pp. 39-47
-
-
Paoletti, P.1
Neyton, J.2
-
44
-
-
33847769253
-
Structure and mechanism of kainate receptor modulation by anions
-
Plested AJ & Mayer ML (2007). Structure and mechanism of kainate receptor modulation by anions. Neuron 53, 829-841.
-
(2007)
Neuron
, vol.53
, pp. 829-841
-
-
Plested, A.J.1
Mayer, M.L.2
-
45
-
-
44649169115
-
Molecular basis of kainate receptor modulation by sodium
-
Plested AJ, Vijayan R, Biggin PC & Mayer ML (2008). Molecular basis of kainate receptor modulation by sodium. Neuron 58, 720-735.
-
(2008)
Neuron
, vol.58
, pp. 720-735
-
-
Plested, A.J.1
Vijayan, R.2
Biggin, P.C.3
Mayer, M.L.4
-
46
-
-
33845416936
-
Block of kainate receptor desensitization uncovers a key trafficking checkpoint
-
Priel A, Selak S, Lerma J & Stern-Bach Y (2006). Block of kainate receptor desensitization uncovers a key trafficking checkpoint. Neuron 52, 1037-1046.
-
(2006)
Neuron
, vol.52
, pp. 1037-1046
-
-
Priel, A.1
Selak, S.2
Lerma, J.3
Stern-Bach, Y.4
-
47
-
-
77952052813
-
Subunit arrangement in N-methyl-d-aspartate (NMDA) receptors
-
Rambhadran A, Gonzalez J & Jayaraman V (2010). Subunit arrangement in N-methyl-d-aspartate (NMDA) receptors. J Biol Chem 285, 15296-15301.
-
(2010)
J Biol Chem
, vol.285
, pp. 15296-15301
-
-
Rambhadran, A.1
Gonzalez, J.2
Jayaraman, V.3
-
48
-
-
84859502370
-
An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors
-
Riou M, Stroebel D, Edwardson JM & Paoletti P (2012). An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors. PLoS One 7, e35134.
-
(2012)
PLoS One
, vol.7
, pp. e35134
-
-
Riou, M.1
Stroebel, D.2
Edwardson, J.M.3
Paoletti, P.4
-
49
-
-
79952280700
-
Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers
-
Rossmann M, Sukumaran M, Penn AC, Veprintsev DB, Babu MM & Greger IH (2011). Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers. EMBO J 30, 959-971.
-
(2011)
EMBO J
, vol.30
, pp. 959-971
-
-
Rossmann, M.1
Sukumaran, M.2
Penn, A.C.3
Veprintsev, D.B.4
Babu, M.M.5
Greger, I.H.6
-
51
-
-
84876022012
-
Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain
-
Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML & Subramaniam S (2013). Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain. Proc Natl Acad Sci U S A 110, 5921-5926.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 5921-5926
-
-
Schauder, D.M.1
Kuybeda, O.2
Zhang, J.3
Klymko, K.4
Bartesaghi, A.5
Borgnia, M.J.6
Mayer, M.L.7
Subramaniam, S.8
-
52
-
-
62149085091
-
Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors
-
Schwenk J, Harmel N, Zolles G, Bildl W, Kulik A, Heimrich B, Chisaka O, Jonas P, Schulte U, Fakler B & Klocker N (2009). Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Science 323, 1313-1319.
-
(2009)
Science
, vol.323
, pp. 1313-1319
-
-
Schwenk, J.1
Harmel, N.2
Zolles, G.3
Bildl, W.4
Kulik, A.5
Heimrich, B.6
Chisaka, O.7
Jonas, P.8
Schulte, U.9
Fakler, B.10
Klocker, N.11
-
53
-
-
77249102565
-
Contribution of the global subunit structure and stargazin on the maturation of AMPA receptors
-
Shanks NF, Maruo T, Farina AN, Ellisman MH & Nakagawa T (2010). Contribution of the global subunit structure and stargazin on the maturation of AMPA receptors. J Neurosci 30, 2728-2740.
-
(2010)
J Neurosci
, vol.30
, pp. 2728-2740
-
-
Shanks, N.F.1
Maruo, T.2
Farina, A.N.3
Ellisman, M.H.4
Nakagawa, T.5
-
54
-
-
84920165039
-
Structure and gating of tetrameric glutamate receptors
-
Sobolevsky AI (2013). Structure and gating of tetrameric glutamate receptors. J Physiol, doi:10.1113/jphysiol.2013.264911.
-
(2013)
J Physiol
-
-
Sobolevsky, A.I.1
-
55
-
-
72049124287
-
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
-
Sobolevsky AI, Rosconi MP & Gouaux E (2009). X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature 462, 745-756.
-
(2009)
Nature
, vol.462
, pp. 745-756
-
-
Sobolevsky, A.I.1
Rosconi, M.P.2
Gouaux, E.3
-
56
-
-
0028559605
-
Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins
-
Stern-Bach Y, Bettler B, Hartley M, Sheppard PO, O'Hara PJ & Heinemann SF (1994). Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron 13, 1345-1357.
-
(1994)
Neuron
, vol.13
, pp. 1345-1357
-
-
Stern-Bach, Y.1
Bettler, B.2
Hartley, M.3
Sheppard, P.O.4
O'Hara, P.J.5
Heinemann, S.F.6
-
57
-
-
0032191104
-
A point mutation in the glutamate binding site blocks desensitization of AMPA receptors
-
Stern-Bach Y, Russo S, Neuman M & Rosenmund C (1998). A point mutation in the glutamate binding site blocks desensitization of AMPA receptors. Neuron 21, 907-918.
-
(1998)
Neuron
, vol.21
, pp. 907-918
-
-
Stern-Bach, Y.1
Russo, S.2
Neuman, M.3
Rosenmund, C.4
-
58
-
-
84861001245
-
The regulation of glutamate receptor trafficking and function by TARPs and other transmembrane auxiliary subunits
-
Straub C & Tomita S (2012). The regulation of glutamate receptor trafficking and function by TARPs and other transmembrane auxiliary subunits. Curr Opin Neurobiol 22, 488-495.
-
(2012)
Curr Opin Neurobiol
, vol.22
, pp. 488-495
-
-
Straub, C.1
Tomita, S.2
-
59
-
-
84858125462
-
AMPA receptor assembly: atomic determinants and built-in modulators
-
In, eds Kreutz MR & Sala C . Springer-Verlag.
-
Sukumaran M, Penn AC & Greger IH (2012). AMPA receptor assembly: atomic determinants and built-in modulators. In Synaptic Plasticity, eds Kreutz MR & Sala C, pp. 241-264. Springer-Verlag.
-
(2012)
Synaptic Plasticity
, pp. 241-264
-
-
Sukumaran, M.1
Penn, A.C.2
Greger, I.H.3
-
60
-
-
0037118049
-
Mechanism of glutamate receptor desensitization
-
Sun Y, Olson R, Horning M, Armstrong N, Mayer M & Gouaux E (2002). Mechanism of glutamate receptor desensitization. Nature 417, 245-253.
-
(2002)
Nature
, vol.417
, pp. 245-253
-
-
Sun, Y.1
Olson, R.2
Horning, M.3
Armstrong, N.4
Mayer, M.5
Gouaux, E.6
-
61
-
-
79960285866
-
Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation
-
Timm DE, Benveniste M, Weeks AM, Nisenbaum ES & Partin KM (2011). Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol Pharmacol 80, 267-280.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 267-280
-
-
Timm, D.E.1
Benveniste, M.2
Weeks, A.M.3
Nisenbaum, E.S.4
Partin, K.M.5
-
62
-
-
77952363301
-
Glutamate receptor ion channels: structure, regulation, and function
-
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ & Dingledine R (2010). Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev 62, 405-496.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 405-496
-
-
Traynelis, S.F.1
Wollmuth, L.P.2
McBain, C.J.3
Menniti, F.S.4
Vance, K.M.5
Ogden, K.K.6
Hansen, K.B.7
Yuan, H.8
Myers, S.J.9
Dingledine, R.10
-
63
-
-
84868660479
-
Zinc potentiates GluK3 glutamate receptor function by stabilizing the ligand binding domain dimer interface
-
Veran J, Kumar J, Pinheiro PS, Athane A, Mayer ML, Perrais D & Mulle C (2012). Zinc potentiates GluK3 glutamate receptor function by stabilizing the ligand binding domain dimer interface. Neuron 76, 565-578.
-
(2012)
Neuron
, vol.76
, pp. 565-578
-
-
Veran, J.1
Kumar, J.2
Pinheiro, P.S.3
Athane, A.4
Mayer, M.L.5
Perrais, D.6
Mulle, C.7
-
64
-
-
78651076694
-
Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators
-
Ward SE, Harries M, Aldegheri L, Austin NE, Ballantine S, Ballini E, Bradley DM, Bax BD, Clarke BP, Harris AJ et al. (2011). Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators. J Med Chem 54, 78-94.
-
(2011)
J Med Chem
, vol.54
, pp. 78-94
-
-
Ward, S.E.1
Harries, M.2
Aldegheri, L.3
Austin, N.E.4
Ballantine, S.5
Ballini, E.6
Bradley, D.M.7
Bax, B.D.8
Clarke, B.P.9
Harris, A.J.10
-
65
-
-
33845361493
-
Conformational restriction blocks glutamate receptor desensitization
-
Weston MC, Schuck P, Ghosal A, Rosenmund C & Mayer ML (2006). Conformational restriction blocks glutamate receptor desensitization. Nat Struct Mol Biol 13, 1120-1127.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 1120-1127
-
-
Weston, M.C.1
Schuck, P.2
Ghosal, A.3
Rosenmund, C.4
Mayer, M.L.5
-
66
-
-
34250806504
-
- dipole couples agonist binding to kainate receptor activation
-
- dipole couples agonist binding to kainate receptor activation. J Neurosci 27, 6800-6809.
-
(2007)
J Neurosci
, vol.27
, pp. 6800-6809
-
-
Wong, A.Y.1
MacLean, D.M.2
Bowie, D.3
-
67
-
-
33749176816
-
Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6
-
Zhang Y, Nayeem N, Nanao MH & Green T (2006). Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6. J Neurosci 26, 10033-10042.
-
(2006)
J Neurosci
, vol.26
, pp. 10033-10042
-
-
Zhang, Y.1
Nayeem, N.2
Nanao, M.H.3
Green, T.4
|