The interleukin-15 system suppresses T cell-mediated autoimmunity by regulating negative selection and nTH17 cell homeostasis in the thymus

Journal of Autoimmunity

Volumn 56, Issue , 2015, Pages 118-129

  Hou, Mau Sheng ^a,c   Huang, Shih Ting ^b,c   Tsai, Ming Han ^c   Yen, Ching Cheng ^c,d   Lai, Yein Gei ^c   Liou, Yae Huei ^c   Lin, Chih Kung ^e   Liao, Nan Shih ^a,b,c  

^a ACADEMIA SINICA   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

IL 15; IL 15R ; Negative selection; NTH17; Thymus

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; INTERLEUKIN 17; AUTOANTIBODY;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL SELECTION; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HOMEOSTASIS; IMMUNOFLUORESCENCE; INFANT; LYMPH NODE; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PHENOTYPE; SALIVARY GLAND; SPLEEN CELL; T LYMPHOCYTE; THYMOCYTE; THYMUS; ANIMAL; ANTIGEN MEDIATED CLONAL SELECTION; BLOOD; DEFICIENCY; GENE EXPRESSION; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY; RADIATION DOSE; T LYMPHOCYTE SUBPOPULATION; TH17 CELL;

ANIMALS; ANTIGEN-PRESENTING CELLS; AUTOANTIBODIES; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CLONAL SELECTION, ANTIGEN-MEDIATED; FEMALE; GENE EXPRESSION; HOMEOSTASIS; IMMUNOPHENOTYPING; INTERLEUKIN-15; INTERLEUKIN-15 RECEPTOR ALPHA SUBUNIT; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; PHENOTYPE; RADIATION TOLERANCE; SALIVARY GLANDS; T-LYMPHOCYTE SUBSETS; TH17 CELLS; THYMOCYTES; THYMUS GLAND;

EID: 84920148926     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2014.11.003     Document Type: Article

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