The role of IL-15 in activating STAT5 and fine-tuning IL-17A production in CD4 T lymphocytes

Journal of Immunology

Volumn 189, Issue 9, 2012, Pages 4237-4246

  Pandiyan, Pushpa ^a,b,e   Yang, Xiang Ping ^c   Saravanamuthu, Senthil S ^d   Zheng, Lixin ^a   Ishihara, Satoru ^a   O'Shea, John J ^c   Lenardo, Michael J ^a,e  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^d NATIONAL EYE INSTITUTE   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 17; MONOCLONAL ANTIBODY; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STAT5 PROTEIN; TRANSCRIPTION FACTOR FOXP3;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DISEASE SEVERITY; DOWN REGULATION; GENE LOCUS; IN VITRO STUDY; LYMPHOCYTE CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SUPERNATANT; TH17 CELL; WILD TYPE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; INTERLEUKIN-15; INTERLEUKIN-17; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TH17 CELLS; UP-REGULATION;

EID: 84867911546     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201476     Document Type: Article

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