Synthesis and characterization of a library of in-situ curing, nonswelling ethoxylated polyol thiol-ene hydrogels for tailorable macromolecule delivery

Advanced Materials

Volumn 27, Issue 1, 2014, Pages 65-72

  O'Shea, Timothy M ^a   Aimetti, Alex A ^b   Kim, Eunha ^a   Yesilyurt, Volkan ^a,c   Langer, Robert ^a,d  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b InVivo Therapeutics Corporation   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d Massachusetts Institute of Technology   (United States)

Author keywords

Candida antarctica lipase B; Drug delivery; Hydrogels; Polymeric materials; Thiol michael addition

Indexed keywords

ADDITION REACTIONS; ALCOHOLS; BIOCOMPATIBILITY; DRUG DELIVERY; POLYMERS; SYNTHESIS (CHEMICAL);

BIODEGRADABLE HYDROGELS; CANDIDA ANTARCTICA LIPASE B; LOCAL DRUG DELIVERY; MATERIAL DEGRADATION; MICHAEL ADDITIONS; SYNTHESIS AND CHARACTERIZATIONS; TEMPORAL CONTROLS; TRANSESTERFICATION;

HYDROGELS;

BIOMATERIAL; HYDROGEL; MACROGOL DERIVATIVE; MACROMOLECULE; POLY(ETHYLENE GLYCOL)DIACRYLATE; POLYMER; POLYOL;

ADMINISTRATION AND DOSAGE; ANIMAL; BIODEGRADABLE IMPLANT; CELL LINE; CELL SURVIVAL; CHEMISTRY; DIFFUSION; DRUG DELIVERY SYSTEM; HYDROGEL; KINETICS; MACROMOLECULE; MATERIALS TESTING; PERMEABILITY; PHARMACOKINETICS; SYNTHESIS; TEMPERATURE; THERAPEUTIC USE; TISSUE SCAFFOLD;

ABSORBABLE IMPLANTS; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE; CELL SURVIVAL; DIFFUSION; DRUG DELIVERY SYSTEMS; HYDROGELS; KINETICS; MACROMOLECULAR SUBSTANCES; MATERIALS TESTING; PERMEABILITY; POLYETHYLENE GLYCOLS; POLYMERS; TEMPERATURE; TISSUE SCAFFOLDS;

EID: 84920131356     PISSN: 09359648     EISSN: 15214095     Source Type: Journal    
DOI: 10.1002/adma.201403724     Document Type: Article

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