PyroGlu-Leu inhibits the induction of inducible nitric oxide synthase in interleukin-1β-stimulated primary cultured rat hepatocytes

Nitric Oxide - Biology and Chemistry

Volumn 44, Issue , 2015, Pages 81-87

  Oishi, Masaharu ^a   Kiyono, Tamami ^b   Sato, Kenji ^b   Tokuhara, Katsuji ^a   Tanaka, Yoshito ^a   Miki, Hirokazu ^a   Nakatake, Richi ^a   Kaibori, Masaki ^a   Nishizawa, Mikio ^c   Okumura, Tadayoshi ^a,c   Kon, Masanori ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY   (Japan)

^c RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

Inducible nitric oxide synthase; iNOS gene antisense transcript; Liver protective effect; Nuclear factor B; Primary cultured hepatocytes; Pyroglutamyl leucine

Indexed keywords

COLLAGENASE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; MESSENGER RNA; NITRIC OXIDE; PYROGLUTAMYLLEUCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DIPEPTIDE; NOS2 PROTEIN, RAT; PYROGLUTAMIC ACID;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELL STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSFECTION; HEPATITIS; IN VITRO STUDY; LIVER CELL; MALE; MESSENGER RNA SYNTHESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIMARY CELL CULTURE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RNA STABILITY; SIGNAL TRANSDUCTION; TRANSACTIVATION; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; TRANSCRIPTION INITIATION; WISTAR RAT;

RATTUS; TRITICUM AESTIVUM;

ANIMALS; CELLS, CULTURED; DIPEPTIDES; HEPATOCYTES; INTERLEUKIN-1BETA; MALE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PYRROLIDONECARBOXYLIC ACID; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION;

EID: 84920111532     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2014.12.005     Document Type: Article

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