Sivelestat suppresses iNOS gene expression in proinflammatory cytokine-stimulated hepatocytes

Digestive Diseases and Sciences

Volumn 56, Issue 6, 2011, Pages 1672-1681

  Araki, Yoshiro ^a   Matsumiya, Miho ^a   Matsuura, Takashi ^a   Kaibori, Masaki ^a   Okumura, Tadayoshi ^a,b   Nishizawa, Mikio ^b   Kwon, A Hon ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

Antisense transcript; Inducible nitric oxide synthase; Interleukin 1 ; Liver injury; mRNA stabilization; Nuclear factor B; Primary cultured hepatocytes; Sivelestat; Type I interleukin 1 receptor

Indexed keywords

I KAPPA B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR TYPE I; MESSENGER RNA; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT INTERLEUKIN 1BETA; SIVELESTAT; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; GENETIC TRANSFECTION; IN VITRO STUDY; LIVER CELL; LIVER PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; CYTOKINES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCINE; HEPATOCYTES; MALE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, WISTAR; RNA, MESSENGER; SERINE PROTEINASE INHIBITORS; SULFONAMIDES;

EID: 79959739102     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-010-1520-y     Document Type: Article

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