Toxicity, genotoxicity and proinflammatory effects of amorphous nanosilica in the human intestinal Caco-2 cell line

Toxicology in Vitro

Volumn 29, Issue 2, 2015, Pages 398-407

  Tarantini, Adeline ^a   Lanceleur, Rachelle ^a   Mourot, Annick ^a   Lavault, Marie Thérèse ^b   Casterou, Gérald ^c   Jarry, Gérard ^a   Hogeveen, Kevin ^a   Fessard, Valérie ^a  

^a Agence Nationale de Sécurité Sanitaire Unité de Toxicologie des Contaminants Bâtiment BioAgroPolis ^*  (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c INSTITUT DES SCIENCES CHIMIQUES DE RENNES   (France)

Author keywords

Caco 2; Genotoxicity; Inflammation; Nanoparticle; Oxidative stress; Silica

Indexed keywords

CASPASE 3; H2AFX PROTEIN, HUMAN; HISTONE; INTERLEUKIN 8; MUTAGENIC AGENT; NANOPARTICLE; SILICON DIOXIDE;

APOPTOSIS; CACO 2 CELL LINE; CELL SURVIVAL; CYTOPLASM; DRUG EFFECTS; HUMAN; METABOLISM; MICRONUCLEUS TEST; OXIDATIVE STRESS; PARTICLE SIZE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

APOPTOSIS; CACO-2 CELLS; CASPASE 3; CELL SURVIVAL; CYTOPLASM; HISTONES; HUMANS; INTERLEUKIN-8; MICRONUCLEUS TESTS; MICROSCOPY, ELECTRON, TRANSMISSION; MUTAGENS; NANOPARTICLES; OXIDATIVE STRESS; PARTICLE SIZE; SILICON DIOXIDE;

EID: 84920073677     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.10.023     Document Type: Article

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