메뉴 건너뛰기




Volumn 8, Issue 1, 2014, Pages 503-513

Impact of protein modification on the protein corona on nanoparticles and nanoparticle-cell interactions

Author keywords

binding affinity; cellular uptake; equilibrium constant; nanoparticles; protein corona; quantum dots

Indexed keywords

BINDING AFFINITIES; CELLULAR UPTAKE; FLUORESCENCE CORRELATION SPECTROSCOPY; HUMAN SERUM ALBUMINS; PHYSICO-CHEMICAL CHANGES; PHYSICOCHEMICAL PROPERTY; PROTEIN CORONAS; PROTEIN MODIFICATIONS;

EID: 84893439836     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn405019v     Document Type: Article
Times cited : (353)

References (85)
  • 1
    • 84881308513 scopus 로고    scopus 로고
    • New Views on Cellular Uptake and Trafficking of Manufactured Nanoparticles
    • Treuel, L.; Jiang, X.; Nienhaus, G. U. New Views on Cellular Uptake and Trafficking of Manufactured Nanoparticles J. R. Soc. Interface 2013, 10, 1742-5662
    • (2013) J. R. Soc. Interface , vol.10 , pp. 1742-5662
    • Treuel, L.1    Jiang, X.2    Nienhaus, G.U.3
  • 2
    • 77957298110 scopus 로고    scopus 로고
    • Lysosomal Degradation of the Carboxydextran Shell of Coated Superparamagnetic Iron Oxide Nanoparticles and the Fate of Professional Phagocytes
    • Lunov, O.; Syrovets, T.; Röcker, C.; Tron, K.; Nienhaus, G. U.; Rasche, V.; Mailänder, V.; Landfester, K.; Simmet, T. Lysosomal Degradation of the Carboxydextran Shell of Coated Superparamagnetic Iron Oxide Nanoparticles and the Fate of Professional Phagocytes Biomaterials 2010, 31, 9015-9022
    • (2010) Biomaterials , vol.31 , pp. 9015-9022
    • Lunov, O.1    Syrovets, T.2    Röcker, C.3    Tron, K.4    Nienhaus, G.U.5    Rasche, V.6    Mailänder, V.7    Landfester, K.8    Simmet, T.9
  • 3
    • 63449105617 scopus 로고    scopus 로고
    • Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells
    • Asha Rani, P. V.; Low Kah Mun, G.; Hande, M. P.; Valiyaveettil, S. Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells ACS Nano 2008, 3, 279-290
    • (2008) ACS Nano , vol.3 , pp. 279-290
    • Asha Rani, P.V.1    Low Kah Mun, G.2    Hande, M.P.3    Valiyaveettil, S.4
  • 6
    • 33847789142 scopus 로고    scopus 로고
    • Understanding the Nanoparticle-Protein Corona Using Methods to Quantify Exchange Rates and Affinities of Proteins for Nanoparticles
    • Cedervall, T.; Lynch, I.; Lindman, S.; Berggard, T.; Thulin, E.; Nilsson, H.; Dawson, K. A.; Linse, S. Understanding the Nanoparticle-Protein Corona Using Methods to Quantify Exchange Rates and Affinities of Proteins for Nanoparticles Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 2050-2055
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 2050-2055
    • Cedervall, T.1    Lynch, I.2    Lindman, S.3    Berggard, T.4    Thulin, E.5    Nilsson, H.6    Dawson, K.A.7    Linse, S.8
  • 7
    • 55749091647 scopus 로고    scopus 로고
    • Nanoparticle Size and Surface Properties Determine the Protein Corona with Possible Implications for Biological Impacts
    • Lundqvist, M.; Stigler, J.; Elia, G.; Lynch, I.; Cedervall, T.; Dawson, K. A. Nanoparticle Size and Surface Properties Determine the Protein Corona with Possible Implications for Biological Impacts Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 14265-14270
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 14265-14270
    • Lundqvist, M.1    Stigler, J.2    Elia, G.3    Lynch, I.4    Cedervall, T.5    Dawson, K.A.6
  • 8
    • 70249141572 scopus 로고    scopus 로고
    • A Quantitative Fluorescence Study of Protein Monolayer Formation on Colloidal Nanoparticles
    • Röcker, C.; Pötzl, M.; Zhang, F.; Parak, W. J.; Nienhaus, G. U. A Quantitative Fluorescence Study of Protein Monolayer Formation on Colloidal Nanoparticles Nat. Nanotechnol. 2009, 4, 577-580
    • (2009) Nat. Nanotechnol. , vol.4 , pp. 577-580
    • Röcker, C.1    Pötzl, M.2    Zhang, F.3    Parak, W.J.4    Nienhaus, G.U.5
  • 9
    • 78349240627 scopus 로고    scopus 로고
    • The Influence of Surface Composition of Nanoparticles on Their Interactions with Serum Albumin
    • Treuel, L.; Malissek, M.; Gebauer, J. S.; Zellner, R. The Influence of Surface Composition of Nanoparticles on Their Interactions with Serum Albumin ChemPhysChem 2010, 11, 3093-3099
    • (2010) ChemPhysChem , vol.11 , pp. 3093-3099
    • Treuel, L.1    Malissek, M.2    Gebauer, J.S.3    Zellner, R.4
  • 10
    • 33847781099 scopus 로고    scopus 로고
    • Probing the Interactions of Proteins and Nanoparticles
    • Klein, J. Probing the Interactions of Proteins and Nanoparticles Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 2029-2030
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 2029-2030
    • Klein, J.1
  • 11
    • 77956425677 scopus 로고    scopus 로고
    • Bionanoscience: Nano Meets Bio at the Interface
    • Leszczynski, J. Bionanoscience: Nano Meets Bio at the Interface Nat. Nanotechnol. 2010, 5, 633-634
    • (2010) Nat. Nanotechnol. , vol.5 , pp. 633-634
    • Leszczynski, J.1
  • 12
    • 79952302512 scopus 로고    scopus 로고
    • Physical-Chemical Aspects of Protein Corona: Relevance to in Vitro and in Vivo Biological Impacts of Nanoparticles
    • Monopoli, M. P.; Walczyk, D.; Campbell, A.; Elia, G.; Lynch, I.; Baldelli Bombelli, F.; Dawson, K. A. Physical-Chemical Aspects of Protein Corona: Relevance to in Vitro and in Vivo Biological Impacts of Nanoparticles J. Am. Chem. Soc. 2011, 133, 2525-2534
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 2525-2534
    • Monopoli, M.P.1    Walczyk, D.2    Campbell, A.3    Elia, G.4    Lynch, I.5    Baldelli Bombelli, F.6    Dawson, K.A.7
  • 14
    • 29844434629 scopus 로고    scopus 로고
    • Gold Nanoparticle-Cytochrome c Complexes: The Effect of Nanoparticle Ligand Charge on Protein Structure
    • Aubin-Tam, M.-E.; Hamad-Schifferli, K. Gold Nanoparticle-Cytochrome c Complexes: The Effect of Nanoparticle Ligand Charge on Protein Structure Langmuir 2005, 21, 12080-12084
    • (2005) Langmuir , vol.21 , pp. 12080-12084
    • Aubin-Tam, M.-E.1    Hamad-Schifferli, K.2
  • 15
    • 33645459798 scopus 로고    scopus 로고
    • Surface Tailoring for Controlled Protein Adsorption: Effect of Topography at the Nanometer Scale and Chemistry
    • Roach, P.; Farrar, D.; Perry, C. C. Surface Tailoring for Controlled Protein Adsorption: Effect of Topography at the Nanometer Scale and Chemistry J. Am. Chem. Soc. 2006, 128, 3939-3945
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 3939-3945
    • Roach, P.1    Farrar, D.2    Perry, C.C.3
  • 17
    • 4043075579 scopus 로고    scopus 로고
    • Silica Nanoparticle Size Influences the Structure and Enzymatic Activity of Adsorbed Lysozyme
    • Vertegel, A. A.; Siegel, R. W.; Dordic, J. S. Silica Nanoparticle Size Influences the Structure and Enzymatic Activity of Adsorbed Lysozyme Langmuir 2004, 20, 6800-6807
    • (2004) Langmuir , vol.20 , pp. 6800-6807
    • Vertegel, A.A.1    Siegel, R.W.2    Dordic, J.S.3
  • 18
    • 20644457548 scopus 로고    scopus 로고
    • The Interactions of 9,10-Phenantrenequinone with Glyceraldehyde-3- phosphatedehydrogenase (GAPDH), a Potential Site for Toxic Actions
    • Rodriguez, C. E.; Fukuto, J. M.; Taguchi, K.; Froines, J.; Cho, A. K. The Interactions of 9,10-Phenantrenequinone with Glyceraldehyde-3- phosphatedehydrogenase (GAPDH), a Potential Site for Toxic Actions Chem.-Biol. Interact. 2005, 155, 97-110
    • (2005) Chem.-Biol. Interact. , vol.155 , pp. 97-110
    • Rodriguez, C.E.1    Fukuto, J.M.2    Taguchi, K.3    Froines, J.4    Cho, A.K.5
  • 19
    • 33646183969 scopus 로고    scopus 로고
    • Detecting Cryptic Epitopes Created by Nanoparticles
    • Lynch, I.; Dawson, K. A.; Linse, S. Detecting Cryptic Epitopes Created by Nanoparticles Science STKE 2006, 2006, pe14
    • (2006) Science STKE , vol.2006 , pp. 14
    • Lynch, I.1    Dawson, K.A.2    Linse, S.3
  • 21
    • 33646774999 scopus 로고    scopus 로고
    • Adsorption-Induced Conformational Changes of Proteins onto Ceramic Particles: Differential Scanning Calorimetry and FTIR Analysis
    • Brandes, N.; Welzel, P. B.; Werner, C.; Kroh, L. W. Adsorption-Induced Conformational Changes of Proteins onto Ceramic Particles: Differential Scanning Calorimetry and FTIR Analysis J. Colloid Interface Sci. 2006, 299, 56-69
    • (2006) J. Colloid Interface Sci. , vol.299 , pp. 56-69
    • Brandes, N.1    Welzel, P.B.2    Werner, C.3    Kroh, L.W.4
  • 23
    • 33751253462 scopus 로고    scopus 로고
    • Nanoparticles as Potential Oral Delivery Systems of Proteins and Vaccines: A Mechanistic Approach
    • des Rieux, A.; Fievez, V.; Garinot, M.; Schneider, Y.-J.; Préat, V. Nanoparticles as Potential Oral Delivery Systems of Proteins and Vaccines: A Mechanistic Approach J. Controlled Release 2006, 116, 1-27
    • (2006) J. Controlled Release , vol.116 , pp. 1-27
    • Des Rieux, A.1    Fievez, V.2    Garinot, M.3    Schneider, Y.-J.4    Préat, V.5
  • 26
    • 31944451232 scopus 로고    scopus 로고
    • Toxic Potential of Materials at the Nanolevel
    • Nel, A.; Xia, T.; Mädler, L.; Li, N. Toxic Potential of Materials at the Nanolevel Science 2006, 311, 622-627
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Mädler, L.3    Li, N.4
  • 27
    • 70350662339 scopus 로고    scopus 로고
    • Promises, Facts and Challenges for Carbon Nanotubes in Imaging and Therapeutics
    • Kostarelos, K.; Bianco, A.; Prato, M. Promises, Facts and Challenges for Carbon Nanotubes in Imaging and Therapeutics Nat. Nanotechnol. 2009, 4, 627-633
    • (2009) Nat. Nanotechnol. , vol.4 , pp. 627-633
    • Kostarelos, K.1    Bianco, A.2    Prato, M.3
  • 29
    • 22244488749 scopus 로고    scopus 로고
    • Oral Delivery of Peptide Drugs: Barriers and Developments
    • Hamman, J. H.; Enslin, G. M.; Kotze, A. F. Oral Delivery of Peptide Drugs: Barriers and Developments BioDrugs 2005, 19, 165-177
    • (2005) BioDrugs , vol.19 , pp. 165-177
    • Hamman, J.H.1    Enslin, G.M.2    Kotze, A.F.3
  • 30
    • 29144461657 scopus 로고    scopus 로고
    • Polymeric Nanoparticles for Oral Delivery of Drugs and Vaccines: A Critical Evaluation of in Vivo Studies
    • Galindo-Rodriguez, S. A.; Allemann, E.; Fessi, H.; Doelker, E. Polymeric Nanoparticles for Oral Delivery of Drugs and Vaccines: A Critical Evaluation of in Vivo Studies Crit. Rev. Ther. Drug Carrier Syst. 2005, 22, 419-464
    • (2005) Crit. Rev. Ther. Drug Carrier Syst. , vol.22 , pp. 419-464
    • Galindo-Rodriguez, S.A.1    Allemann, E.2    Fessi, H.3    Doelker, E.4
  • 32
    • 0033136871 scopus 로고    scopus 로고
    • Enzymatic Degradation of Poly(Epsilon-Caprolactone)/Poly(DL-Lactide) Blends in Phosphate Buffer Solution
    • Gan, Z. H.; Yu, D. H.; Zhong, Z. Y.; Liang, Q. Z.; Jing, X. B. Enzymatic Degradation of Poly(Epsilon-Caprolactone)/Poly(DL-Lactide) Blends in Phosphate Buffer Solution Polymer 1999, 40, 2859-2862
    • (1999) Polymer , vol.40 , pp. 2859-2862
    • Gan, Z.H.1    Yu, D.H.2    Zhong, Z.Y.3    Liang, Q.Z.4    Jing, X.B.5
  • 34
    • 10044279371 scopus 로고    scopus 로고
    • Preparation and Characterisation of Antibody Modified Gelatin Nanoparticles as Drug Carrier System for Uptake in Lymphocytes
    • Balthasar, S.; Michaelis, K.; Dinauer, N.; von Kreuter, J.; Langer, K. Preparation and Characterisation of Antibody Modified Gelatin Nanoparticles as Drug Carrier System for Uptake in Lymphocytes Biomaterials 2005, 26, 2723-2732
    • (2005) Biomaterials , vol.26 , pp. 2723-2732
    • Balthasar, S.1    Michaelis, K.2    Dinauer, N.3    Von Kreuter, J.4    Langer, K.5
  • 35
    • 0030758658 scopus 로고    scopus 로고
    • Characterization of the Block Structure and Molecular Weight of Sodium Alginates
    • Johnson, F. A.; Craig, D. Q.; Mercer, A. D. Characterization of the Block Structure and Molecular Weight of Sodium Alginates J. Pharm. Pharmacol. 1997, 49, 639-643
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 639-643
    • Johnson, F.A.1    Craig, D.Q.2    Mercer, A.D.3
  • 36
    • 0037020525 scopus 로고    scopus 로고
    • Paclitaxel-Loaded PLGA Nanoparticles: Preperation, Physicochemical Charactertization and in Vitro Anti-Tumoral Activity
    • Fonseca, C.; Simoes, S.; Gaspar, R. Paclitaxel-Loaded PLGA Nanoparticles: Preperation, Physicochemical Charactertization and in Vitro Anti-Tumoral Activity J. Controlled Release 2002, 83, 273-286
    • (2002) J. Controlled Release , vol.83 , pp. 273-286
    • Fonseca, C.1    Simoes, S.2    Gaspar, R.3
  • 37
    • 0347761356 scopus 로고    scopus 로고
    • Preparation and Characterization of Cationic PLGA Nanospheres as DNA Carriers
    • Kumar Ravi, M. N.; Bakowsky, U.; Lehr, C. M. Preparation and Characterization of Cationic PLGA Nanospheres as DNA Carriers Biomaterials 2004, 25, 1771-1777
    • (2004) Biomaterials , vol.25 , pp. 1771-1777
    • Kumar Ravi, M.N.1    Bakowsky, U.2    Lehr, C.M.3
  • 38
    • 1842789742 scopus 로고    scopus 로고
    • Factorial Design, Physicochemical Characterisation and Acitivity of Ciprofloxacin-PLGA Nanoparticles
    • Dillen, K.; Vandervoort, J.; Van den Mooter, G.; Verheyden, L.; Ludwig, A. Factorial Design, Physicochemical Characterisation and Acitivity of Ciprofloxacin-PLGA Nanoparticles Int. J. Pharm. 2004, 275, 171-187
    • (2004) Int. J. Pharm. , vol.275 , pp. 171-187
    • Dillen, K.1    Vandervoort, J.2    Van Den Mooter, G.3    Verheyden, L.4    Ludwig, A.5
  • 39
    • 0032952283 scopus 로고    scopus 로고
    • PLGA Nanoparticles Prepared by Nanoprecipitation: Drug Loading and Release Studies of a Water Soluble Drug
    • Govender, T.; Stolnik, S.; Garnett, M. C.; Illum, L.; Davis, S. S. PLGA Nanoparticles Prepared by Nanoprecipitation: Drug Loading and Release Studies of a Water Soluble Drug J. Controlled Release 1999, 57, 171-185
    • (1999) J. Controlled Release , vol.57 , pp. 171-185
    • Govender, T.1    Stolnik, S.2    Garnett, M.C.3    Illum, L.4    Davis, S.S.5
  • 40
    • 0345647081 scopus 로고    scopus 로고
    • Polymeric Nanoparticles as Delivery System for Influenza Virus Glycoproteins
    • Lemoine, D.; Preat, V. Polymeric Nanoparticles as Delivery System for Influenza Virus Glycoproteins J. Controlled Release 1998, 54, 15-27
    • (1998) J. Controlled Release , vol.54 , pp. 15-27
    • Lemoine, D.1    Preat, V.2
  • 41
    • 0019848930 scopus 로고
    • Present and Future Applications of Biomaterials in Controlled Drug Delivery Systems
    • Langer, R. S.; Peppas, N. A. Present and Future Applications of Biomaterials in Controlled Drug Delivery Systems Biomaterials 1981, 2, 201-214
    • (1981) Biomaterials , vol.2 , pp. 201-214
    • Langer, R.S.1    Peppas, N.A.2
  • 42
    • 84893461803 scopus 로고    scopus 로고
    • Therapeutic Effects of Leuprorelin Microspheres on Endometriosis and Uterine Leiomyomata
    • Miller, J. D.; Anderson, M. G. Therapeutic Effects of Leuprorelin Microspheres on Endometriosis and Uterine Leiomyomata Adv. Drug Delivery Rev. 1997, 60, 179-155
    • (1997) Adv. Drug Delivery Rev. , vol.60 , pp. 179-155
    • Miller, J.D.1    Anderson, M.G.2
  • 43
    • 15744404419 scopus 로고    scopus 로고
    • Subconjunctivally Administered Celecoxib-PLGA Microparticles Sustain Retinal Drug Levels and Alleviate Diabetes-Induced Oxidative Stress in a Rat Model
    • Ayalasomayajula, S. P.; Kompella, U. B. Subconjunctivally Administered Celecoxib-PLGA Microparticles Sustain Retinal Drug Levels and Alleviate Diabetes-Induced Oxidative Stress in a Rat Model Eur. J. Pharm. Biopharm. 2005, 511, 191-198
    • (2005) Eur. J. Pharm. Biopharm. , vol.511 , pp. 191-198
    • Ayalasomayajula, S.P.1    Kompella, U.B.2
  • 45
    • 0141892711 scopus 로고    scopus 로고
    • In Vivo Conjunctival Reconstruction Using Modified PLGA Grafts for Decreased Scar Formation and Contraction
    • Lee, S. Y.; Oh, J. H.; Kim, Y. H.; Kim, S. H.; Choi, J. W. In Vivo Conjunctival Reconstruction Using Modified PLGA Grafts for Decreased Scar Formation and Contraction Biomaterials 2003, 24, 5049-5059
    • (2003) Biomaterials , vol.24 , pp. 5049-5059
    • Lee, S.Y.1    Oh, J.H.2    Kim, Y.H.3    Kim, S.H.4    Choi, J.W.5
  • 46
    • 0031723078 scopus 로고    scopus 로고
    • Development of a Multiple-Drug Delivery Implant for Intraocular Management of Proliferative Vitreoretinopathy
    • Zhou, T.; Lewis, H.; Foster, R. E.; Schwendman, S. P. Development of a Multiple-Drug Delivery Implant for Intraocular Management of Proliferative Vitreoretinopathy J. Controlled Release 1998, 55, 281-295
    • (1998) J. Controlled Release , vol.55 , pp. 281-295
    • Zhou, T.1    Lewis, H.2    Foster, R.E.3    Schwendman, S.P.4
  • 47
    • 80052727425 scopus 로고    scopus 로고
    • Characterization of Protein Adsorption onto Fept Nanoparticles Using Dual-Focus Fluorescence Correlation Spectroscopy
    • Maffre, P.; Nienhaus, K.; Amin, F.; Parak, W. J.; Nienhaus, G. U. Characterization of Protein Adsorption onto Fept Nanoparticles Using Dual-Focus Fluorescence Correlation Spectroscopy Beilstein J. Nanotechnol. 2011, 2, 374-383
    • (2011) Beilstein J. Nanotechnol. , vol.2 , pp. 374-383
    • Maffre, P.1    Nienhaus, K.2    Amin, F.3    Parak, W.J.4    Nienhaus, G.U.5
  • 48
    • 0026664548 scopus 로고
    • Atomic Structure and Chemistry of Human Serum Albumin
    • He, X. M.; Carter, D. C. Atomic Structure and Chemistry of Human Serum Albumin Nature 1992, 358, 209-215
    • (1992) Nature , vol.358 , pp. 209-215
    • He, X.M.1    Carter, D.C.2
  • 49
    • 3242886771 scopus 로고    scopus 로고
    • Pdb2pqr: An Automated Pipeline for the Setup of Poisson-Boltzmann Electrostatics Calculations
    • Dolinsky, T. J.; Nielsen, J. E.; McCammon, J. A.; Baker, N. A. Pdb2pqr: An Automated Pipeline for the Setup of Poisson-Boltzmann Electrostatics Calculations Nucleic Acids Res. 2004, 32, W665-W667
    • (2004) Nucleic Acids Res. , vol.32
    • Dolinsky, T.J.1    Nielsen, J.E.2    McCammon, J.A.3    Baker, N.A.4
  • 50
    • 0014176153 scopus 로고
    • Antigenicity of Chemically Modified Bovine Serum Albumin
    • Habeeb, A. F. S. Antigenicity of Chemically Modified Bovine Serum Albumin J. Immunol. 1967, 99, 1264-1276
    • (1967) J. Immunol. , vol.99 , pp. 1264-1276
    • Habeeb, A.F.S.1
  • 51
    • 0027361964 scopus 로고
    • Novel, Negatively Charged, Human Serum Albumins Display Potent and Selective in-Vitro Anti-Human-Immunodeficiency-Virus Type-1 Activity
    • Jansen, R. W.; Schols, D.; Pauwels, R.; Declercq, E.; Meijer, D. K. F. Novel, Negatively Charged, Human Serum Albumins Display Potent and Selective in-Vitro Anti-Human-Immunodeficiency-Virus Type-1 Activity Mol. Pharmacol. 1993, 44, 1003-1007
    • (1993) Mol. Pharmacol. , vol.44 , pp. 1003-1007
    • Jansen, R.W.1    Schols, D.2    Pauwels, R.3    Declercq, E.4    Meijer, D.K.F.5
  • 53
    • 0012014988 scopus 로고    scopus 로고
    • Succinylation of Proteins
    • Walker, J. Humana Press: Towota, NJ
    • Aitken, A.; Learmonth, M. Succinylation of Proteins. In The Protein Protocols Handbook; Walker, J., Ed.; Humana Press: Towota, NJ, 1996; pp 343-344.
    • (1996) The Protein Protocols Handbook , pp. 343-344
    • Aitken, A.1    Learmonth, M.2
  • 54
    • 0033880469 scopus 로고    scopus 로고
    • Sensitivity Enhancement in Fluorescence Correlation Spectroscopy of Multiple Species Using Time-Gated Detection
    • Lamb, D. C.; Schenk, A.; Röcker, C.; Scalfi-Happ, C.; Nienhaus, G. U. Sensitivity Enhancement in Fluorescence Correlation Spectroscopy of Multiple Species Using Time-Gated Detection Biophys. J. 2000, 79, 1129-1138
    • (2000) Biophys. J. , vol.79 , pp. 1129-1138
    • Lamb, D.C.1    Schenk, A.2    Röcker, C.3    Scalfi-Happ, C.4    Nienhaus, G.U.5
  • 55
    • 0030671161 scopus 로고    scopus 로고
    • Fluorescence Correlation Spectroscopy: Diagnostics for Sparse Molecules
    • Maiti, S.; Haupts, U.; Webb, W. W. Fluorescence Correlation Spectroscopy: Diagnostics for Sparse Molecules Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 11753-11757
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 11753-11757
    • Maiti, S.1    Haupts, U.2    Webb, W.W.3
  • 56
    • 1642514526 scopus 로고    scopus 로고
    • Confocal Optics Microscopy for Biochemical and Cellular High-Throughput Screening
    • Zemanová, L.; Schenk, A.; Valler, M. J.; Nienhaus, G. U.; Heilker, R. Confocal Optics Microscopy for Biochemical and Cellular High-Throughput Screening Drug Discovery Today 2003, 8, 1085-1093
    • (2003) Drug Discovery Today , vol.8 , pp. 1085-1093
    • Zemanová, L.1    Schenk, A.2    Valler, M.J.3    Nienhaus, G.U.4    Heilker, R.5
  • 57
    • 84864741149 scopus 로고    scopus 로고
    • Toward a Molecular Understanding of Nanoparticle-Protein Interactions
    • Treuel, L.; Nienhaus, G. U. Toward a Molecular Understanding of Nanoparticle-Protein Interactions Biophys. Rev. 2012, 4, 137-147
    • (2012) Biophys. Rev. , vol.4 , pp. 137-147
    • Treuel, L.1    Nienhaus, G.U.2
  • 58
    • 78649624650 scopus 로고    scopus 로고
    • Endo- and Exocytosis of Zwitterionic Quantum Dot Nanoparticles by Live HeLa Cells
    • Jiang, X.; Röcker, C.; Hafner, M.; Brandholt, S.; Dörlich, R. M.; Nienhaus, G. U. Endo- and Exocytosis of Zwitterionic Quantum Dot Nanoparticles by Live HeLa Cells ACS Nano 2010, 4, 6787-6797
    • (2010) ACS Nano , vol.4 , pp. 6787-6797
    • Jiang, X.1    Röcker, C.2    Hafner, M.3    Brandholt, S.4    Dörlich, R.M.5    Nienhaus, G.U.6
  • 60
    • 79956129886 scopus 로고    scopus 로고
    • Specific Effects of Surface Carboxyl Groups on Anionic Polystyrene Particles in Their Interactions with Mesenchymal Stem Cells
    • Jiang, X.; Musyanovych, A.; Röcker, C.; Landfester, K.; Mailänder, V.; Nienhaus, G. U. Specific Effects of Surface Carboxyl Groups on Anionic Polystyrene Particles in Their Interactions with Mesenchymal Stem Cells Nanoscale 2011, 3, 2028-2035
    • (2011) Nanoscale , vol.3 , pp. 2028-2035
    • Jiang, X.1    Musyanovych, A.2    Röcker, C.3    Landfester, K.4    Mailänder, V.5    Nienhaus, G.U.6
  • 61
    • 84857772044 scopus 로고    scopus 로고
    • Cellular Uptake of Nanoparticles by Membrane Penetration: A Study Combining Confocal Microscopy with FTIR Spectroelectrochemistry
    • Wang, T.; Bai, J.; Jiang, X.; Nienhaus, G. U. Cellular Uptake of Nanoparticles by Membrane Penetration: A Study Combining Confocal Microscopy with FTIR Spectroelectrochemistry ACS Nano 2012, 6, 1251-1259
    • (2012) ACS Nano , vol.6 , pp. 1251-1259
    • Wang, T.1    Bai, J.2    Jiang, X.3    Nienhaus, G.U.4
  • 65
    • 84864241697 scopus 로고    scopus 로고
    • Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells
    • Lesniak, A.; Fenaroli, F.; Monopoli, M. P.; Åberg, C.; Dawson, K. A.; Salvati, A. Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells ACS Nano 2012, 6, 5845-5857
    • (2012) ACS Nano , vol.6 , pp. 5845-5857
    • Lesniak, A.1    Fenaroli, F.2    Monopoli, M.P.3    Åberg, C.4    Dawson, K.A.5    Salvati, A.6
  • 66
    • 84865747005 scopus 로고    scopus 로고
    • Ultrasmall Fluorescent Silver Nanoclusters: Protein Adsorption and Its Effects on Cellular Responses
    • Shang, L.; Dörlich, R. M.; Trouillet, V.; Bruns, M.; Nienhaus, G. U. Ultrasmall Fluorescent Silver Nanoclusters: Protein Adsorption and Its Effects on Cellular Responses Nano Res. 2012, 5, 531-542
    • (2012) Nano Res. , vol.5 , pp. 531-542
    • Shang, L.1    Dörlich, R.M.2    Trouillet, V.3    Bruns, M.4    Nienhaus, G.U.5
  • 68
    • 78650317021 scopus 로고    scopus 로고
    • Scavenger Receptors Mediate Cellular Uptake of Polyvalent Oligonucleotide-Functionalized Gold Nanoparticles
    • Patel, P. C.; Giljohann, D. A.; Daniel, W. L.; Zheng, D.; Prigodich, A. E.; Mirkin, C. A. Scavenger Receptors Mediate Cellular Uptake of Polyvalent Oligonucleotide-Functionalized Gold Nanoparticles Bioconjugate Chem. 2010, 21, 2250-2256
    • (2010) Bioconjugate Chem. , vol.21 , pp. 2250-2256
    • Patel, P.C.1    Giljohann, D.A.2    Daniel, W.L.3    Zheng, D.4    Prigodich, A.E.5    Mirkin, C.A.6
  • 69
    • 78449260866 scopus 로고    scopus 로고
    • Modeling Receptor-Mediated Endocytosis of Polymer-Functionalized Iron Oxide Nanoparticles by Human Macrophages
    • Lunov, O.; Zablotskii, V.; Syrovets, T.; Röcker, C.; Tron, K.; Nienhaus, G. U.; Simmet, T. Modeling Receptor-Mediated Endocytosis of Polymer-Functionalized Iron Oxide Nanoparticles by Human Macrophages Biomaterials 2011, 32, 547-555
    • (2011) Biomaterials , vol.32 , pp. 547-555
    • Lunov, O.1    Zablotskii, V.2    Syrovets, T.3    Röcker, C.4    Tron, K.5    Nienhaus, G.U.6    Simmet, T.7
  • 70
    • 84875861757 scopus 로고    scopus 로고
    • Mechanistic Aspects of Fluorescent Gold Nanocluster Internalization by Live HeLa Cells
    • Yang, L.; Shang, L.; Nienhaus, G. U. Mechanistic Aspects of Fluorescent Gold Nanocluster Internalization by Live HeLa Cells Nanoscale 2013, 5, 1537-1543
    • (2013) Nanoscale , vol.5 , pp. 1537-1543
    • Yang, L.1    Shang, L.2    Nienhaus, G.U.3
  • 71
    • 0032214525 scopus 로고    scopus 로고
    • Surface-Modified Biodegradable Albumin Nano- and Microspheres. II: Effect of Surface Charges on in Vitro Phagocytosis and Biodistribution in Rats
    • Roser, M.; Fischer, D.; Kissel, T. Surface-Modified Biodegradable Albumin Nano- and Microspheres. II: Effect of Surface Charges on in Vitro Phagocytosis and Biodistribution in Rats Eur. J. Pharm. Biopharm. 1998, 46, 255-263
    • (1998) Eur. J. Pharm. Biopharm. , vol.46 , pp. 255-263
    • Roser, M.1    Fischer, D.2    Kissel, T.3
  • 72
    • 65749117793 scopus 로고    scopus 로고
    • Nanoparticle Interaction with Plasma Proteins as It Relates to Particle Biodistribution, Biocompatibility and Therapeutic Efficacy
    • Aggarwal, P.; Hall, J. B.; McLeland, C. B.; Dobrovolskaia, M. A.; McNeil, S. E. Nanoparticle Interaction with Plasma Proteins as It Relates to Particle Biodistribution, Biocompatibility and Therapeutic Efficacy Adv. Drug Delivery Rev. 2009, 61, 428-437
    • (2009) Adv. Drug Delivery Rev. , vol.61 , pp. 428-437
    • Aggarwal, P.1    Hall, J.B.2    McLeland, C.B.3    Dobrovolskaia, M.A.4    McNeil, S.E.5
  • 73
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, Biodistribution, and Pharmacokinetics of Polymeric Nanoparticles
    • Owens, D. E., III; Peppas, N. A. Opsonization, Biodistribution, and Pharmacokinetics of Polymeric Nanoparticles Int. J. Pharm. 2006, 307, 93-102
    • (2006) Int. J. Pharm. , vol.307 , pp. 93-102
    • Owens III, D.E.1    Peppas, N.A.2
  • 74
    • 80053328840 scopus 로고    scopus 로고
    • Nanoparticle Size Is a Critical Physicochemical Determinant of the Human Blood Plasma Corona: A Comprehensive Quantitative Proteomic Analysis
    • Tenzer, S.; Docter, D.; Rosfa, S.; Wlodarski, A.; Kuharev, J.; Rekik, A.; Knauer, S. K.; Bantz, C.; Nawroth, T.; Bier, C. et al. Nanoparticle Size Is a Critical Physicochemical Determinant of the Human Blood Plasma Corona: A Comprehensive Quantitative Proteomic Analysis ACS Nano 2011, 5, 7155-7167
    • (2011) ACS Nano , vol.5 , pp. 7155-7167
    • Tenzer, S.1    Docter, D.2    Rosfa, S.3    Wlodarski, A.4    Kuharev, J.5    Rekik, A.6    Knauer, S.K.7    Bantz, C.8    Nawroth, T.9    Bier, C.10
  • 77
    • 84864920957 scopus 로고    scopus 로고
    • Quantifying the Influence of Polymer Coatings on the Serum Albumin Corona Formation around Silver and Gold Nanoparticles
    • Treuel, L.; Malissek, M.; Grass, S.; Diendorf, J.; Mahl, D.; Meyer-Zaika, W.; Epple, M. Quantifying the Influence of Polymer Coatings on the Serum Albumin Corona Formation around Silver and Gold Nanoparticles J. Nanopart. Res. 2012, 14, 1-12
    • (2012) J. Nanopart. Res. , vol.14 , pp. 1-12
    • Treuel, L.1    Malissek, M.2    Grass, S.3    Diendorf, J.4    Mahl, D.5    Meyer-Zaika, W.6    Epple, M.7
  • 78
    • 70349547210 scopus 로고    scopus 로고
    • Zwitterionic Biocompatible Quantum Dots for Wide pH Stability and Weak Nonspecific Binding to Cells
    • Breus, V. V.; Heyes, C. D.; Tron, K.; Nienhaus, G. U. Zwitterionic Biocompatible Quantum Dots for Wide pH Stability and Weak Nonspecific Binding to Cells ACS Nano 2009, 3, 2573-2580
    • (2009) ACS Nano , vol.3 , pp. 2573-2580
    • Breus, V.V.1    Heyes, C.D.2    Tron, K.3    Nienhaus, G.U.4
  • 79
    • 34250195863 scopus 로고    scopus 로고
    • Capping of CdSe-ZnS Quantum Dots with Dhla and Subsequent Conjugation with Proteins
    • Clapp, A. R.; Goldman, E. R.; Mattoussi, H. Capping of CdSe-ZnS Quantum Dots with Dhla and Subsequent Conjugation with Proteins Nat. Protocols 2006, 1, 1258-1266
    • (2006) Nat. Protocols , vol.1 , pp. 1258-1266
    • Clapp, A.R.1    Goldman, E.R.2    Mattoussi, H.3
  • 81
    • 4444316252 scopus 로고    scopus 로고
    • Biocompatible Surfaces for Specific Tethering of Individual Protein Molecules
    • Heyes, C. D.; Kobitski, A. Y.; Amirgoulova, E. V.; Nienhaus, G. U. Biocompatible Surfaces for Specific Tethering of Individual Protein Molecules J. Phys. Chem. B 2004, 108, 13387-13394
    • (2004) J. Phys. Chem. B , vol.108 , pp. 13387-13394
    • Heyes, C.D.1    Kobitski, A.Y.2    Amirgoulova, E.V.3    Nienhaus, G.U.4
  • 82
    • 46749085102 scopus 로고    scopus 로고
    • Sculpting an RNA Conformational Energy Landscape by a Methyl Group Modification - A Single-Molecule FRET Study
    • Kobitski, A. Y.; Hengesbach, M.; Helm, M.; Nienhaus, G. U. Sculpting an RNA Conformational Energy Landscape by a Methyl Group Modification-a Single-Molecule FRET Study Angew. Chem., Int. Ed. 2008, 47, 4326-4330
    • (2008) Angew. Chem., Int. Ed. , vol.47 , pp. 4326-4330
    • Kobitski, A.Y.1    Hengesbach, M.2    Helm, M.3    Nienhaus, G.U.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.