PKM2 depletion induces the compensation of glutaminolysis through β-catenin/c-Myc pathway in tumor cells

Cellular Signalling

Volumn 26, Issue 11, 2014, Pages 2397-2405

  Wu, Haili ^a   Li, Zongwei ^a   Yang, Peng ^a   Zhang, Lichao ^a   Fan, Yongsheng ^b   Li, Zhuoyu ^a,b  

^a SHANXI UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Compensation; Glutaminolysis; M2 type pyruvate kinase; MiR 200a; Catenin c Myc

Indexed keywords

BETA CATENIN; DEOXYGLUCOSE; DIMER; M2 TYPE PYRUVATE KINASE; MICRORNA 200A; MYC PROTEIN; PYRUVATE KINASE; UNCLASSIFIED DRUG; ANTIMETABOLITE; CARRIER PROTEIN; GLUTAMINE; MEMBRANE PROTEIN; MICRORNA; MIRN200 MICRORNA, HUMAN; MYC PROTEIN, HUMAN; RNA; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS;

AMINO ACID METABOLISM; ARTICLE; CELL SURVIVAL; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; GLUTAMINOLYSIS; GLYCOLYSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR CELL; COLON TUMOR; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HEPG2 CELL LINE; HUMAN; METABOLISM; PATHOLOGY;

ANTIMETABOLITES; BETA CATENIN; CARRIER PROTEINS; CELL SURVIVAL; COLONIC NEOPLASMS; DEOXYGLUCOSE; GLUTAMINE; GLYCOLYSIS; HEK293 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; MEMBRANE PROTEINS; MICRORNAS; PROTO-ONCOGENE PROTEINS C-MYC; PYRUVATE KINASE; RNA, NEOPLASM; SIGNAL TRANSDUCTION; THYROID HORMONES;

EID: 84920055991     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.07.024     Document Type: Article

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