메뉴 건너뛰기




Volumn 21, Issue 4, 2014, Pages 399-406

Blood-brain barrier transport of short proline-rich antimicrobial peptides

Author keywords

Antimicrobial peptides; Bio distribution; Blood brain barrier; Cell penetrating peptides; In vivo; Stability; Transport

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT; PROLINE RICH ANTIMICROBIAL PEPTIDE API137; PROLINE RICH ANTIMICROBIAL PEPTIDE DROSOCIN; PROLINE RICH ANTIMICROBIAL PEPTIDE DROSOCIN PROLINE 5 HYDROXYPROLINE; PROLINE RICH ANTIMICROBIAL PEPTIDE ONCOCIN; UNCLASSIFIED DRUG;

EID: 84896327594     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/09298665113206660110     Document Type: Article
Times cited : (36)

References (33)
  • 1
    • 84872806450 scopus 로고    scopus 로고
    • The future of antibiotics and resistance
    • Spellberg, B.; Bartlett, J.G.; Gilbert, D.N. The Future of Antibiotics and Resistance. N. Eng. J. Med., 2013, 368(4), 299-302.
    • (2013) N. Eng. J. Med , vol.368 , Issue.4 , pp. 299-302
    • Spellberg, B.1    Bartlett, J.G.2    Gilbert, D.N.3
  • 2
    • 0036633301 scopus 로고    scopus 로고
    • The short proline-rich antibacterial peptide family
    • Otvos, L. Jr. The short proline-rich antibacterial peptide family. Cell. Mol. Life Sci., 2002, 59(7), 1138-1150.
    • (2002) Cell. Mol. Life Sci , vol.59 , Issue.7 , pp. 1138-1150
    • Otvos Jr., L.1
  • 3
    • 84865431287 scopus 로고    scopus 로고
    • Overview on the recent study of antimicrobial peptides: Origins, functions, relative mechanisms and application
    • Li, Y.; Xiang, Q.; Zhang, Q.; Huang, Y.; Su, Z. Overview on the recent study of antimicrobial peptides: Origins, functions, relative mechanisms and application. Peptides, 2012, 37(2), 207-215.
    • (2012) Peptides , vol.37 , Issue.2 , pp. 207-215
    • Li, Y.1    Xiang, Q.2    Zhang, Q.3    Huang, Y.4    Su, Z.5
  • 4
    • 79960961765 scopus 로고    scopus 로고
    • Proline-rich antimicrobial peptides: Converging to a non-lytic mechanism of action
    • Scocchi, M.; Tossi, A.; Gennaro, R. Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action. Cell. Mol. Life Sci., 2011, 68(13), 2317-2330.
    • (2011) Cell. Mol. Life Sci , vol.68 , Issue.13 , pp. 2317-2330
    • Scocchi, M.1    Tossi, A.2    Gennaro, R.3
  • 6
    • 84872048892 scopus 로고    scopus 로고
    • Novel Apidaecin 1b Analogs with Superior Serum Stabilities for Treatment of Infections by Gram-Negative Pathogens
    • Berthold, N.; Czihal, P.; Fritsche, S.; Sauer, U.; Schiffer, G.; Knappe, D.; Alber, G.; Hoffmann, R. Novel Apidaecin 1b Analogs with Superior Serum Stabilities for Treatment of Infections by Gram-Negative Pathogens. Antimicrob. Agents Ch., 2013, 57(1), 402-409.
    • (2013) Antimicrob. Agents Ch , vol.57 , Issue.1 , pp. 402-409
    • Berthold, N.1    Czihal, P.2    Fritsche, S.3    Sauer, U.4    Schiffer, G.5    Knappe, D.6    Alber, G.7    Hoffmann, R.8
  • 7
    • 77954725852 scopus 로고    scopus 로고
    • Oncocin (VDKPPYLP RPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens
    • Knappe, D.; Piantavigna, S.; Hansen, A.; Mechler, A.; Binas, A.; Nolte, O.; Martin, L.L.; Hoffmann, R. Oncocin (VDKPPYLP RPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens. J. Med. Chem., 2010, 53(14), 5240-5247.
    • (2010) J. Med. Chem , vol.53 , Issue.14 , pp. 5240-5247
    • Knappe, D.1    Piantavigna, S.2    Hansen, A.3    Mechler, A.4    Binas, A.5    Nolte, O.6    Martin, L.L.7    Hoffmann, R.8
  • 8
    • 84866318155 scopus 로고    scopus 로고
    • Intracellular toxicity of proline-rich antimicrobial peptides shuttled into mammalian cells by the cell-penetrating peptide penetratin
    • Hansen, A.; Schäfer, I.; Knappe, D.; Seibel, P.; Hoffmann, R. Intracellular Toxicity of Proline-Rich Antimicrobial Peptides Shuttled into Mammalian Cells by the Cell-Penetrating Peptide Penetratin. Antimicrob. Agents Chemother., 2012, 56(10), 5194-5201.
    • (2012) Antimicrob. Agents Chemother , vol.56 , Issue.10 , pp. 5194-5201
    • Hansen, A.1    Schäfer, I.2    Knappe, D.3    Seibel, P.4    Hoffmann, R.5
  • 9
    • 14844318492 scopus 로고    scopus 로고
    • Cerebral infections
    • Karampekios, S.; Hesselink, J. Cerebral infections. Eur. Radiol., 2005, 15(3), 485-493.
    • (2005) Eur. Radiol , vol.15 , Issue.3 , pp. 485-493
    • Karampekios, S.1    Hesselink, J.2
  • 10
    • 67649675075 scopus 로고    scopus 로고
    • Treatment strategies for central nervous system infections
    • Kim, K.S. Treatment strategies for central nervous system infections. Expert Opin. Pharmacother., 2009, 10(8), 1307-1317.
    • (2009) Expert Opin. Pharmacother , vol.10 , Issue.8 , pp. 1307-1317
    • Kim, K.S.1
  • 13
    • 0034126420 scopus 로고    scopus 로고
    • New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy
    • Rousselle, C.; Clair, P.; Lefauconnier, J.-M.; Kaczorek, M.; Scherrmann, J.-M.; Temsamani, J. New Advances in the Transport of Doxorubicin through the Blood-Brain Barrier by a Peptide Vector-Mediated Strategy. Mol. Pharmacol., 2000, 57(4), 679-686.
    • (2000) Mol. Pharmacol , vol.57 , Issue.4 , pp. 679-686
    • Rousselle, C.1    Clair, P.2    Lefauconnier, J.-M.3    Kaczorek, M.4    Scherrmann, J.-M.5    Temsamani, J.6
  • 16
    • 33749385780 scopus 로고    scopus 로고
    • Cell-penetrating peptides and antimicrobial peptides: How different are they?
    • Henriques, S.T.; Melo, M.N.; Castanho, M.A.R.B. Cell-penetrating peptides and antimicrobial peptides: how different are they? Biochem. J., 2006, 399, 1-7.
    • (2006) Biochem. J , vol.399 , pp. 1-7
    • Henriques, S.T.1    Melo, M.N.2    Castanho, M.A.R.B.3
  • 17
    • 33744999374 scopus 로고    scopus 로고
    • Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects
    • Palm, C.; Netzereab, S.; Hällbrink, M. Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects. Peptides, 2006, 27(7), 1710-1716.
    • (2006) Peptides , vol.27 , Issue.7 , pp. 1710-1716
    • Palm, C.1    Netzereab, S.2    Hällbrink, M.3
  • 19
    • 80052575530 scopus 로고    scopus 로고
    • Cellular uptake of Aib-containing amphipathic helix peptide
    • Wada, S.-i.; Tsuda, H.; Okada, T.; Urata, H. Cellular uptake of Aib-containing amphipathic helix peptide. Bioorg. Med. Chem. Lett., 2011, 21(19), 5588-5691.
    • (2011) Bioorg. Med. Chem. Lett , vol.21 , Issue.19 , pp. 5588-5691
    • Wada, S.-I.1    Tsuda, H.2    Okada, T.3    Urata, H.4
  • 21
    • 84896358193 scopus 로고    scopus 로고
    • Hydroxyproline substitutions stabilize non-glycosylated drosocin against serum proteases without challenging its antibacterial activity
    • Knappe, D.; Cassone, M.; Nollmann, F.I.; Otvos, L. Jr.; Hoffmann, R. Hydroxyproline substitutions stabilize non-glycosylated drosocin against serum proteases without challenging its antibacterial activity. Protein Pept. Lett., 2013, 21(4), 321-9.
    • (2013) Protein Pept. Lett , vol.21 , Issue.4 , pp. 321-329
    • Knappe, D.1    Cassone, M.2    Nollmann, F.I.3    Otvos Jr., L.4    Hoffmann, R.5
  • 22
    • 52049107373 scopus 로고    scopus 로고
    • In vitro metabolic stability of obestatin: Kinetics and identification of cleavage products
    • Vergote, V.; Van Dorpe, S.; Peremans, K.; Burvenich, C.; De Spiegeleer, B. In vitro metabolic stability of obestatin: Kinetics and identification of cleavage products. Peptides, 2008, 29(10), 1740-1748.
    • (2008) Peptides , vol.29 , Issue.10 , pp. 1740-1748
    • Vergote, V.1    Van Dorpe, S.2    Peremans, K.3    Burvenich, C.4    De Spiegeleer, B.5
  • 25
    • 0020956774 scopus 로고
    • Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
    • Patlak, C.S.; Blasberg, R.G.; Fenstermacher, J.D. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J. Cerebr. Blood F. Met., 1983, 3(1), 1-7.
    • (1983) J. Cerebr. Blood F. Met , vol.3 , Issue.1 , pp. 1-7
    • Patlak, C.S.1    Blasberg, R.G.2    Fenstermacher, J.D.3
  • 26
    • 0019794669 scopus 로고
    • High-affinity and low-affinity transport of D-glucose from blood to brain
    • Gjedde, A. High-affinity and low-affinity transport of D-glucose from blood to brain. J. Neurochem., 1981, 36(4), 1463-1471.
    • (1981) J. Neurochem , vol.36 , Issue.4 , pp. 1463-1471
    • Gjedde, A.1
  • 27
    • 0025295847 scopus 로고
    • Capillary depletion method for quantification of blood-brain-barrier transport circulating peptides and plasma-proteins
    • Triguero, D.; Buciak, J.; Pardridge, W.M. Capillary depletion method for quantification of blood-brain-barrier transport circulating peptides and plasma-proteins. J. Neurochem., 1990, 54(6), 1882-1888.
    • (1990) J. Neurochem , vol.54 , Issue.6 , pp. 1882-1888
    • Triguero, D.1    Buciak, J.2    Pardridge, W.M.3
  • 28
    • 0027517309 scopus 로고
    • Murine tumor-necrosisfactor- alpha is transported from blood to brain in the mouse
    • Gutierrez, E.G.; Banks, W.A.; Kastin, A.J. Murine tumor-necrosisfactor- alpha is transported from blood to brain in the mouse. J. Neuroimmunol., 1993, 47(2), 169-176.
    • (1993) J. Neuroimmunol , vol.47 , Issue.2 , pp. 169-176
    • Gutierrez, E.G.1    Banks, W.A.2    Kastin, A.J.3
  • 29
    • 0024389581 scopus 로고
    • Quantifying carrier-mediated transport of peptides from brain to the blood
    • Banks, W.A.; Kastin, A.J. Quantifying carrier-mediated transport of peptides from brain to the blood. Method. Enzymol., 1989, 168, 652-660.
    • (1989) Method. Enzymol , vol.168 , pp. 652-660
    • Banks, W.A.1    Kastin, A.J.2
  • 30
    • 77249114385 scopus 로고    scopus 로고
    • Metabolic Fate of Lactoferricin-Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the in vitro Metabolic Stability
    • Svenson, J.; Vergote, V.; Karstad, R.; Burvenich, C.; Svendsen, J. S.; De Spiegeleer, B. Metabolic Fate of Lactoferricin-Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the In vitro Metabolic Stability. J. Pharmacol. Exp. Ther., 2010, 332(3), 1032-1039.
    • (2010) J. Pharmacol. Exp. Ther , vol.332 , Issue.3 , pp. 1032-1039
    • Svenson, J.1    Vergote, V.2    Karstad, R.3    Burvenich, C.4    Svendsen, J.S.5    De Spiegeleer, B.6
  • 32
    • 0035154799 scopus 로고    scopus 로고
    • Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells
    • Stins, M.F.; Badger, J.; Kim, K.S. Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells. Microb. Pathogenesis, 2001, 30(1), 19-28.
    • (2001) Microb. Pathogenesis , vol.30 , Issue.1 , pp. 19-28
    • Stins, M.F.1    Badger, J.2    Kim, K.S.3
  • 33
    • 84877907905 scopus 로고    scopus 로고
    • Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes
    • Ribes, S.; Regen, T.; Meister, T.; Tauber, S.C.; Schütze, S.; Mildner, A.; Mack, M.; Hanisch, U.-K.; Nau, R. Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. Infect. Immun., 2013, 81(5), 1810-1819.
    • (2013) Infect. Immun , vol.81 , Issue.5 , pp. 1810-1819
    • Ribes, S.1    Regen, T.2    Meister, T.3    Tauber, S.C.4    Schütze, S.5    Mildner, A.6    Mack, M.7    Hanisch, U.-K.8    Nau, R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.