-
1
-
-
84872806450
-
The future of antibiotics and resistance
-
Spellberg, B.; Bartlett, J.G.; Gilbert, D.N. The Future of Antibiotics and Resistance. N. Eng. J. Med., 2013, 368(4), 299-302.
-
(2013)
N. Eng. J. Med
, vol.368
, Issue.4
, pp. 299-302
-
-
Spellberg, B.1
Bartlett, J.G.2
Gilbert, D.N.3
-
2
-
-
0036633301
-
The short proline-rich antibacterial peptide family
-
Otvos, L. Jr. The short proline-rich antibacterial peptide family. Cell. Mol. Life Sci., 2002, 59(7), 1138-1150.
-
(2002)
Cell. Mol. Life Sci
, vol.59
, Issue.7
, pp. 1138-1150
-
-
Otvos Jr., L.1
-
3
-
-
84865431287
-
Overview on the recent study of antimicrobial peptides: Origins, functions, relative mechanisms and application
-
Li, Y.; Xiang, Q.; Zhang, Q.; Huang, Y.; Su, Z. Overview on the recent study of antimicrobial peptides: Origins, functions, relative mechanisms and application. Peptides, 2012, 37(2), 207-215.
-
(2012)
Peptides
, vol.37
, Issue.2
, pp. 207-215
-
-
Li, Y.1
Xiang, Q.2
Zhang, Q.3
Huang, Y.4
Su, Z.5
-
4
-
-
79960961765
-
Proline-rich antimicrobial peptides: Converging to a non-lytic mechanism of action
-
Scocchi, M.; Tossi, A.; Gennaro, R. Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action. Cell. Mol. Life Sci., 2011, 68(13), 2317-2330.
-
(2011)
Cell. Mol. Life Sci
, vol.68
, Issue.13
, pp. 2317-2330
-
-
Scocchi, M.1
Tossi, A.2
Gennaro, R.3
-
5
-
-
0034700271
-
Interaction between heat shock proteins and antimicrobial peptides
-
Otvos, L. Jr.; O, I.; Rogers, M.E.; Consolvo, P.J.; Condie, B.A.; Lovas, S.; Bulet, P.; Blaszczyk-Thurin, M. Interaction between Heat Shock Proteins and Antimicrobial Peptides. Biochemistry, 2000, 39(46), 14150-14159.
-
(2000)
Biochemistry
, vol.39
, Issue.46
, pp. 14150-14159
-
-
Otvos Jr., L.1
Rogers, M.E.2
Consolvo, P.J.3
Condie, B.A.4
Lovas, S.5
Bulet, P.6
Blaszczyk-Thurin, M.7
-
6
-
-
84872048892
-
Novel Apidaecin 1b Analogs with Superior Serum Stabilities for Treatment of Infections by Gram-Negative Pathogens
-
Berthold, N.; Czihal, P.; Fritsche, S.; Sauer, U.; Schiffer, G.; Knappe, D.; Alber, G.; Hoffmann, R. Novel Apidaecin 1b Analogs with Superior Serum Stabilities for Treatment of Infections by Gram-Negative Pathogens. Antimicrob. Agents Ch., 2013, 57(1), 402-409.
-
(2013)
Antimicrob. Agents Ch
, vol.57
, Issue.1
, pp. 402-409
-
-
Berthold, N.1
Czihal, P.2
Fritsche, S.3
Sauer, U.4
Schiffer, G.5
Knappe, D.6
Alber, G.7
Hoffmann, R.8
-
7
-
-
77954725852
-
Oncocin (VDKPPYLP RPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens
-
Knappe, D.; Piantavigna, S.; Hansen, A.; Mechler, A.; Binas, A.; Nolte, O.; Martin, L.L.; Hoffmann, R. Oncocin (VDKPPYLP RPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens. J. Med. Chem., 2010, 53(14), 5240-5247.
-
(2010)
J. Med. Chem
, vol.53
, Issue.14
, pp. 5240-5247
-
-
Knappe, D.1
Piantavigna, S.2
Hansen, A.3
Mechler, A.4
Binas, A.5
Nolte, O.6
Martin, L.L.7
Hoffmann, R.8
-
8
-
-
84866318155
-
Intracellular toxicity of proline-rich antimicrobial peptides shuttled into mammalian cells by the cell-penetrating peptide penetratin
-
Hansen, A.; Schäfer, I.; Knappe, D.; Seibel, P.; Hoffmann, R. Intracellular Toxicity of Proline-Rich Antimicrobial Peptides Shuttled into Mammalian Cells by the Cell-Penetrating Peptide Penetratin. Antimicrob. Agents Chemother., 2012, 56(10), 5194-5201.
-
(2012)
Antimicrob. Agents Chemother
, vol.56
, Issue.10
, pp. 5194-5201
-
-
Hansen, A.1
Schäfer, I.2
Knappe, D.3
Seibel, P.4
Hoffmann, R.5
-
9
-
-
14844318492
-
Cerebral infections
-
Karampekios, S.; Hesselink, J. Cerebral infections. Eur. Radiol., 2005, 15(3), 485-493.
-
(2005)
Eur. Radiol
, vol.15
, Issue.3
, pp. 485-493
-
-
Karampekios, S.1
Hesselink, J.2
-
10
-
-
67649675075
-
Treatment strategies for central nervous system infections
-
Kim, K.S. Treatment strategies for central nervous system infections. Expert Opin. Pharmacother., 2009, 10(8), 1307-1317.
-
(2009)
Expert Opin. Pharmacother
, vol.10
, Issue.8
, pp. 1307-1317
-
-
Kim, K.S.1
-
11
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
Abbott, N.J.; Patabendige, A.A.K.; Dolman, D.E.M.; Yusof, S.R.; Begley, D.J. Structure and function of the blood-brain barrier. Neurobiol. Dis., 2010, 37(1), 13-25.
-
(2010)
Neurobiol. Dis
, vol.37
, Issue.1
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.K.2
Dolman, D.E.M.3
Yusof, S.R.4
Begley, D.J.5
-
12
-
-
84864148170
-
Api88 is a novel antibacterial designer peptide to treat systemic infections with multidrug-resistant gram-negative pathogens
-
Czihal, P.; Knappe, D.; Fritsche, S.; Zahn, M.; Berthold, N.; Piantavigna, S.; Müller, U.; Van Dorpe, S.; Herth, N.; Binas, A.; Köhler, G.; De Spiegeleer, B.; Martin, L.L.; Nolte, O.; Sträter, N.; Alber, G.; Hoffmann, R. Api88 Is a Novel Antibacterial Designer Peptide To Treat Systemic Infections with Multidrug-Resistant Gram-Negative Pathogens. ACS Chem. Biol., 2012, 7(7), 1281-1291.
-
(2012)
ACS Chem. Biol
, vol.7
, Issue.7
, pp. 1281-1291
-
-
Czihal, P.1
Knappe, D.2
Fritsche, S.3
Zahn, M.4
Berthold, N.5
Piantavigna, S.6
Müller, U.7
Van Dorpe, S.8
Herth, N.9
Binas, A.10
Köhler, G.11
De Spiegeleer, B.12
Martin, L.L.13
Nolte, O.14
Sträter, N.15
Alber, G.16
Hoffmann, R.17
-
13
-
-
0034126420
-
New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy
-
Rousselle, C.; Clair, P.; Lefauconnier, J.-M.; Kaczorek, M.; Scherrmann, J.-M.; Temsamani, J. New Advances in the Transport of Doxorubicin through the Blood-Brain Barrier by a Peptide Vector-Mediated Strategy. Mol. Pharmacol., 2000, 57(4), 679-686.
-
(2000)
Mol. Pharmacol
, vol.57
, Issue.4
, pp. 679-686
-
-
Rousselle, C.1
Clair, P.2
Lefauconnier, J.-M.3
Kaczorek, M.4
Scherrmann, J.-M.5
Temsamani, J.6
-
14
-
-
0035196836
-
Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: Saturation kinetics and specificity
-
Rousselle, C.; Smirnova, M.; Clair, P.; Lefauconnier, J.-M.; Chavanieu, A.; Calas, B.; Scherrmann, J.-M.; Temsamani, J. Enhanced Delivery of Doxorubicin into the Brain via a Peptide-Vector-Mediated Strategy: Saturation Kinetics and Specificity. Mol. Pharmacol., 2000, 296(1), 124-131.
-
(2000)
Mol. Pharmacol
, vol.296
, Issue.1
, pp. 124-131
-
-
Rousselle, C.1
Smirnova, M.2
Clair, P.3
Lefauconnier, J.-M.4
Chavanieu, A.5
Calas, B.6
Scherrmann, J.-M.7
Temsamani, J.8
-
15
-
-
84881246928
-
Chemical-functional diversity in cell-penetrating peptides
-
Stalmans, S.; Wynendaele, E.; Bracke, N.; Gevaert, B.; D'Hondt, M.; Peremans, K.; Burvenich, C.; De Spiegeleer, B. Chemical-Functional Diversity in Cell-Penetrating Peptides. PLOS ONE, 2013, 8(8), e71752.
-
(2013)
PLOS ONE
, vol.8
, Issue.8
-
-
Stalmans, S.1
Wynendaele, E.2
Bracke, N.3
Gevaert, B.4
D'Hondt, M.5
Peremans, K.6
Burvenich, C.7
De Spiegeleer, B.8
-
16
-
-
33749385780
-
Cell-penetrating peptides and antimicrobial peptides: How different are they?
-
Henriques, S.T.; Melo, M.N.; Castanho, M.A.R.B. Cell-penetrating peptides and antimicrobial peptides: how different are they? Biochem. J., 2006, 399, 1-7.
-
(2006)
Biochem. J
, vol.399
, pp. 1-7
-
-
Henriques, S.T.1
Melo, M.N.2
Castanho, M.A.R.B.3
-
17
-
-
33744999374
-
Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects
-
Palm, C.; Netzereab, S.; Hällbrink, M. Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects. Peptides, 2006, 27(7), 1710-1716.
-
(2006)
Peptides
, vol.27
, Issue.7
, pp. 1710-1716
-
-
Palm, C.1
Netzereab, S.2
Hällbrink, M.3
-
18
-
-
24044459704
-
Uptake of cell-penetrating peptides in yeasts
-
Holm, T.; Netzereab, S.; Hansen, M.; Langel, Ü.; Hällbrink, M. Uptake of cell-penetrating peptides in yeasts. Febs Lett., 2005, 579(23), 5217-5222.
-
(2005)
Febs Lett
, vol.579
, Issue.23
, pp. 5217-5222
-
-
Holm, T.1
Netzereab, S.2
Hansen, M.3
Langel, Ü.4
Hällbrink, M.5
-
19
-
-
80052575530
-
Cellular uptake of Aib-containing amphipathic helix peptide
-
Wada, S.-i.; Tsuda, H.; Okada, T.; Urata, H. Cellular uptake of Aib-containing amphipathic helix peptide. Bioorg. Med. Chem. Lett., 2011, 21(19), 5588-5691.
-
(2011)
Bioorg. Med. Chem. Lett
, vol.21
, Issue.19
, pp. 5588-5691
-
-
Wada, S.-I.1
Tsuda, H.2
Okada, T.3
Urata, H.4
-
20
-
-
33750373810
-
Evaluation of the antibacterial spectrum of drosocin analogues
-
Bikker, F.J.; Kaman-van Zanten, W.E.; de Vries-van de Ruit, A.- M.B.C.; Voskamp-Visser, I.; van Hooft, P.A.V.; Mars-Groenendijk, R.H.; de Visser, P.C.; Noort, D. Evaluation of the Antibacterial Spectrum of Drosocin Analogues. Chem. Biol. Drug Des., 2006, 68(3), 148-153.
-
(2006)
Chem. Biol. Drug des
, vol.68
, Issue.3
, pp. 148-153
-
-
Bikker, F.J.1
Kaman-Van Zanten, W.E.2
De Vries-Van De Ruit, A.-M.B.C.3
Voskamp-Visser, I.4
Van Hooft, P.A.V.5
Mars-Groenendijk, R.H.6
De Visser, P.C.7
Noort, D.8
-
21
-
-
84896358193
-
Hydroxyproline substitutions stabilize non-glycosylated drosocin against serum proteases without challenging its antibacterial activity
-
Knappe, D.; Cassone, M.; Nollmann, F.I.; Otvos, L. Jr.; Hoffmann, R. Hydroxyproline substitutions stabilize non-glycosylated drosocin against serum proteases without challenging its antibacterial activity. Protein Pept. Lett., 2013, 21(4), 321-9.
-
(2013)
Protein Pept. Lett
, vol.21
, Issue.4
, pp. 321-329
-
-
Knappe, D.1
Cassone, M.2
Nollmann, F.I.3
Otvos Jr., L.4
Hoffmann, R.5
-
22
-
-
52049107373
-
In vitro metabolic stability of obestatin: Kinetics and identification of cleavage products
-
Vergote, V.; Van Dorpe, S.; Peremans, K.; Burvenich, C.; De Spiegeleer, B. In vitro metabolic stability of obestatin: Kinetics and identification of cleavage products. Peptides, 2008, 29(10), 1740-1748.
-
(2008)
Peptides
, vol.29
, Issue.10
, pp. 1740-1748
-
-
Vergote, V.1
Van Dorpe, S.2
Peremans, K.3
Burvenich, C.4
De Spiegeleer, B.5
-
23
-
-
34247244193
-
Analysis of iodinated peptides by LC-DAD/ESI ion trap mass spectrometry
-
Vergote, V.; Bodé, S.; Peremans, K.; Vanbree, H.; Baert, B.; Slegers, G.; Burvenich, C.; De Spiegeleer, B. Analysis of iodinated peptides by LC-DAD/ESI ion trap mass spectrometry. J. Chromatogr. B, 2007, 850(1-2), 213-220.
-
(2007)
J. Chromatogr. B
, vol.850
, Issue.1-2
, pp. 213-220
-
-
Vergote, V.1
Bodé, S.2
Peremans, K.3
Vanbree, H.4
Baert, B.5
Slegers, G.6
Burvenich, C.7
De Spiegeleer, B.8
-
24
-
-
36749010124
-
LC-UV/MS characterization and DOE optimization of the iodinated peptide obestatin
-
Vergote, V.; Baert, B.; Vandermeulen, E.; Peremans, K.; van Bree, H.; Slegers, G.; Burvenich, C.; De Spiegeleer, B. LC-UV/MS characterization and DOE optimization of the iodinated peptide obestatin. J. Pharmaceut. Biomed., 2008, 46(1), 127-136.
-
(2008)
J. Pharmaceut. Biomed
, vol.46
, Issue.1
, pp. 127-136
-
-
Vergote, V.1
Baert, B.2
Vandermeulen, E.3
Peremans, K.4
Van Bree, H.5
Slegers, G.6
Burvenich, C.7
De Spiegeleer, B.8
-
25
-
-
0020956774
-
Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
-
Patlak, C.S.; Blasberg, R.G.; Fenstermacher, J.D. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J. Cerebr. Blood F. Met., 1983, 3(1), 1-7.
-
(1983)
J. Cerebr. Blood F. Met
, vol.3
, Issue.1
, pp. 1-7
-
-
Patlak, C.S.1
Blasberg, R.G.2
Fenstermacher, J.D.3
-
26
-
-
0019794669
-
High-affinity and low-affinity transport of D-glucose from blood to brain
-
Gjedde, A. High-affinity and low-affinity transport of D-glucose from blood to brain. J. Neurochem., 1981, 36(4), 1463-1471.
-
(1981)
J. Neurochem
, vol.36
, Issue.4
, pp. 1463-1471
-
-
Gjedde, A.1
-
27
-
-
0025295847
-
Capillary depletion method for quantification of blood-brain-barrier transport circulating peptides and plasma-proteins
-
Triguero, D.; Buciak, J.; Pardridge, W.M. Capillary depletion method for quantification of blood-brain-barrier transport circulating peptides and plasma-proteins. J. Neurochem., 1990, 54(6), 1882-1888.
-
(1990)
J. Neurochem
, vol.54
, Issue.6
, pp. 1882-1888
-
-
Triguero, D.1
Buciak, J.2
Pardridge, W.M.3
-
28
-
-
0027517309
-
Murine tumor-necrosisfactor- alpha is transported from blood to brain in the mouse
-
Gutierrez, E.G.; Banks, W.A.; Kastin, A.J. Murine tumor-necrosisfactor- alpha is transported from blood to brain in the mouse. J. Neuroimmunol., 1993, 47(2), 169-176.
-
(1993)
J. Neuroimmunol
, vol.47
, Issue.2
, pp. 169-176
-
-
Gutierrez, E.G.1
Banks, W.A.2
Kastin, A.J.3
-
29
-
-
0024389581
-
Quantifying carrier-mediated transport of peptides from brain to the blood
-
Banks, W.A.; Kastin, A.J. Quantifying carrier-mediated transport of peptides from brain to the blood. Method. Enzymol., 1989, 168, 652-660.
-
(1989)
Method. Enzymol
, vol.168
, pp. 652-660
-
-
Banks, W.A.1
Kastin, A.J.2
-
30
-
-
77249114385
-
Metabolic Fate of Lactoferricin-Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the in vitro Metabolic Stability
-
Svenson, J.; Vergote, V.; Karstad, R.; Burvenich, C.; Svendsen, J. S.; De Spiegeleer, B. Metabolic Fate of Lactoferricin-Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the In vitro Metabolic Stability. J. Pharmacol. Exp. Ther., 2010, 332(3), 1032-1039.
-
(2010)
J. Pharmacol. Exp. Ther
, vol.332
, Issue.3
, pp. 1032-1039
-
-
Svenson, J.1
Vergote, V.2
Karstad, R.3
Burvenich, C.4
Svendsen, J.S.5
De Spiegeleer, B.6
-
31
-
-
0036891349
-
Brain abscess caused by aerobic Gram-negative bacilli: Clinical features and therapeutic outcomes
-
Rau, C.-S.; Chang, W.-N.; Lin, Y.-C.; Lu, C.-H.; Liliang, P.-C.; Su, T.-M.; Tsai, Y.-D.; Chang, C.-J.; Lee, P.-Y.; Lin, M.-W.; Cheng, B.-C. Brain abscess caused by aerobic Gram-negative bacilli: clinical features and therapeutic outcomes. Clin. Neurol. Neurosur., 2002, 105(1), 60-65.
-
(2002)
Clin. Neurol. Neurosur
, vol.105
, Issue.1
, pp. 60-65
-
-
Rau, C.-S.1
Chang, W.-N.2
Lin, Y.-C.3
Lu, C.-H.4
Liliang, P.-C.5
Su, T.-M.6
Tsai, Y.-D.7
Chang, C.-J.8
Lee, P.-Y.9
Lin, M.-W.10
Cheng, B.-C.11
-
32
-
-
0035154799
-
Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells
-
Stins, M.F.; Badger, J.; Kim, K.S. Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells. Microb. Pathogenesis, 2001, 30(1), 19-28.
-
(2001)
Microb. Pathogenesis
, vol.30
, Issue.1
, pp. 19-28
-
-
Stins, M.F.1
Badger, J.2
Kim, K.S.3
-
33
-
-
84877907905
-
Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes
-
Ribes, S.; Regen, T.; Meister, T.; Tauber, S.C.; Schütze, S.; Mildner, A.; Mack, M.; Hanisch, U.-K.; Nau, R. Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. Infect. Immun., 2013, 81(5), 1810-1819.
-
(2013)
Infect. Immun
, vol.81
, Issue.5
, pp. 1810-1819
-
-
Ribes, S.1
Regen, T.2
Meister, T.3
Tauber, S.C.4
Schütze, S.5
Mildner, A.6
Mack, M.7
Hanisch, U.-K.8
Nau, R.9
|