Antibacterial peptides isolated from insects

Journal of Peptide Science

Volumn 6, Issue 10, 2000, Pages 497-511

  Otvos Jr , Laszlo ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

Antibacterial peptides; Insect peptides; Insects

Indexed keywords

AMINO ACID; APIDAECIN; BACTERIAL PROTEIN; CECROPIN; CECROPIN B; DEFESIN; DIPTERICIN; DROSOCIN; GLYCINE; POLYPEPTIDE ANTIBIOTIC AGENT; PROLINE; PROTEINASE; PYRRHOCORICIN; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID COMPOSITION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIUM DETECTION; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG ISOLATION; DRUG POTENCY; DRUG TARGETING; ENTEROBACTER INFECTION; ESCHERICHIA COLI; GENE ACTIVATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; GROWTH INHIBITION; HEMOLYMPH; IC 50; IN VIVO STUDY; INSECT; ION PERMEABILITY; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; REVIEW; TUMOR GROWTH;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; GENE EXPRESSION REGULATION; INSECT PROTEINS; INSECTS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION;

EID: 0033754189     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1387(200010)6:10<497::AID-PSC277>3.0.CO;2-W     Document Type: Review

References (125)

1. Insect diversity in the fossil record
2. The inducible antibacterial peptides of insects
3. Biological mediators of insect immunity
4. Peptide antibiotics and their role in innate immunity
5. Gene encoded peptide antibiotics and innate immunity. Do 'animacules' have defence budgets?
6. Ancient relationships
7. Antimicrobial peptide defense in Drosophila
8. Antibacterial peptides: Key components needed in immunity
9. The humoral antibacterial response of Drosophila
10. Drosophila antimicrobial peptides
11. Differential display of peptides induced during the immune response of Drosophila: A matrix-assisted laser desorption ionization time-of-flight mass spectrometry study
12. A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense
13. Cloning of the gene encoding the antibacterial peptide drosocin involved in Drosophila immunity. Expression studies during the immune response
14. κB-like motifs regulate the induction of immune genes in Drosophila
15. Function and activation of NF-κB in the immune system
16. The dorsoventral regulatory gene cassette spaetzle/Toll/cactus controls the potent antifungal response in Drosophila adults
17. Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila
18. The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila cecropin gene expression
19. A structural super-family of growth factors containing a cysteine-knot motif
20. Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif
21. Insect immunity. Purification and properties of three inducible bactericidal proteins from hemolymph of immunized pupae of Hyalophora cecropia
22. Sequence and specificity of two antibacterial proteins involved in insect immunity
23. Cell-free immunity in Cecropia. A model system for antibacterial proteins
24. A family of bacteria-regulated, cecropin D-like peptides from Manduca sexta
25. Insect immunity: Isolation and structure of cecropins B and D from pupae of the Chinese oak silk moth, Antheraea pernyi
26. Cloning of cDNAs for cecropins A and B, and expression of the genes in the silkworm, Bombyx mori
27. Primary structure of sarcotoxin I, an antibacterial protein induced in the hemolymph of Sarcophaga peregrina (flesh fly) larvae
28. The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection
29. Sequences of two cDNA clones from the medfly Ceratitis capitata encoding antibacterial peptides of the cecropin family
30. Peptide sequence of an antibiotic cecropin from the vector mosquito, Aedes albopictus
31. Insect defensins: Inducible antibacterial peptides
32. Defensins: Endogenous antibiotic peptides of animal cells
33. Determination of disulfide bridges in natural and recombinant insect defensin A
34. A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata)
35. Insect immunity: Isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides
36. Molecular cloning of cDNA for sapecin and unique expression of the sapecin gene during the development of Sarcophaga peregrina
37. Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity
38. Insect immunity: Isolation of three novel inducible antibacterial defensins from the vector mosquito Aedes aegypti
39. A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin
40. Purification and characterization of a scorpion defensin, a 4 kDa antibacterial peptide presenting structural similarities with insect defensins and scorpion toxins
41. Cysteinerich antimicrobial peptides in invertebrates
42. Isolation, characterization and chemical synthesis of a new insect defensin from Chironomus plumosus (Diptera)
43. A novel inducible antibacterial peptide from Drosophila carries an O-glycosylated substitution
44. Novel inducible antibacterial peptides from a hernipteran insect, the sap sucking-bug Pyrrhocoris apterus
45. Apidaecins: Antibacterial peptides from honeybees
46. Isolation from an ant Myrmecia gulosa of two inducible O-glycosylated proline-rich antibacterial peptides
47. A novel antibacterial peptide family isolated from the silkworm, Bombyx mori
48. A novel member of lebocin gene family from the silkworm, Bombyx mori
49. Enlarged scale chemical synthesis and range of activity of drosocin, an O-glycosylated antibacterial peptide from Drosophila
50. Range of activity and metabolic stability of synthetic antibacterial glycopeptides from insects
51. A strategy for the chemoselective synthesis of O-linked glycopeptides with native sugar-peptide linkages
52. Synthesis of an oxime-linked neoglycopeptide with glycosylation-dependent activity similar to its native counterpart
53. Identification of early genes in the Drosophila immune response by PCR-based differential display: The Attacin A gene and the evolution of attacin-like proteins
54. Inhibitory effect of sarcotoxin IIA, an antibacterial protein of Sarcophaga peregrina, on growth of Escherichia coli
55. Purification and characterization of a dipteran homologue from Sarcophaga peregrina (flesh fly)
56. Insect immunity - Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides
57. Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity
58. A matrix-assisted laser desorption ionization time-of-flight mass spectrometry approach to identify the origin of the glycan heterogeneity of diptericin, an O-glycosylated antibacterial peptide from insects
59. Chemical synthesis, antibacterial activity and conformation of diptericin, an 82-mer peptide originally isolated from insects
60. A chemically synthesized version of the insect antibacterial glycopeptide, diptericin, disrupts bacterial membrane integrity
61. Fmoc-based synthesis of peptide-thioesters: Application to the total chemical synthesis of a glycoprotein by native chemical ligation
62. Functional and chemical characterization of Hymenoptaecin, an antibacterial polypeptide that is infection-inducible in the honeybee (Apis mellifera)
63. Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family
64. Purification and molecular cloning of cDNA for an inducible antibacterial protein of larvae of a coleopteran insect. Holotrichia diomphalia
65. Acaloleptins A: Inducible antibacterial peptides from larvae of the beetle, Acalolepta luxuriosa
66. Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides
67. Peptides with antimicrobial activity of the brevinin-1 family isolated from skin secretions of the southern leopard frog, Rana sphenocephala
68. Moricin, a novel type of antibacterial peptide isolated from the silkworm, Bombyx mori
69. Multiple-antibiotic-resistant bacteria
70. Animal antimicrobial peptides: An overview
71. Structure-function relationships of antimicrobial peptides
72. Production in Escherichia of moricin, a novel type antibacterial peptide from the silkworm, Bombyx mori
73. Synthetic glycopeptide and phosphopeptide models of an antibacterial fragment of chromogranin A
74. Effects on electrophoretic mobility and antibacterial spectrum of removal of two residues from synthetic sarcotoxin IA and addition of the same residues to cecropin B
75. The solution conformation of the antibacterial peptide cecropin A: A nuclear magnetic resonance and dynamical simulated annealing study
76. The structure of the mammalian antibacterial peptide cecropin P1 in solution, determined by proton-NMR
77. Circular dichroism of biological membranes. 1. Mitochondria and red blood cell ghosts
78. Mode of action of the antibacterial cecropin B2: A spectrofluorometric study
79. Orientation of cecropin A helices in phospholipid bi-layers determined by solid-state NMR spectroscopy
80. Formation of pores in Escherichia coli cell membranes by a cecropin isolated from hemolymph of Heliothis virescens larvae
81. Antibacterial peptides designed as analogs or hybrids of cecropins and melittin
82. Insect defensin, an inducible antibacterial peptide, forms voltage-dependent channels in Micrococcus luteus
83. Identification and characterization of the antimicrobial peptide corresponding to C-terminal β-sheet domain of tenecin 1, an antibacterial protein of larvae of Tenebrio molitor
84. Agents that increase the permeability of the outer membrane
85. +)-channel by sapecin B, an insect antibacterial protein
86. Refined three-dimensional solution structure of insect defensin A
87. 1H nuclear magnetic resonance study of the solution conformation of an antibacterial protein, sapecin
88. NMR studies of defensin antimicrobial peptides. 2. Three-dimensional structures of rabbit NP-2 and human HNP-1
89. Crystal structure of defensin HNP-3, an amphiphilic dimer: Mechanisms of membrane permeabilization
90. Defensins: A family of antimicrobial and cytotoxic peptides
91. Defensins: Antimicrobial and cytotoxic peptides of mammalian cells
92. Structure and dynamics of the neutrophil defensins NP-2, NP-5, and HNP-1: NMR studies of amide hydrogen exchange kinetics
93. Insect peptides with improved protease resistance protect mice against bacterial infection
94. Apidaecin-type peptide antibiotics function through a non-poreforming mechanism involving stereospecificity
95. All-D amino acid-containing channel-forming antibiotic peptides
96. Lethal effects of apidaecin on Escherichia coli involve sequential molecular interactions with diverse targets
97. Conformational studies by NMR of the anti-microbial peptide, drosocin and its non-glycosylated derivative: Effects of glycosylation on solution conformation
98. Reverse turns in peptides and proteins
99. The antibacterial effect of attacins from the silk moth Hyalophora cecropia is directed against the outer membrane of Escherichia coli
100. Insect immunity. Attacins, a family of antibacterial proteins from Hyalophora cecropia
101. Attacin, an antibacterial protein from Hyalophora cecropia, inhibits synthesis of outer membrane proteins in Escherichia coli by interfering with omp gene transcription
102. Solution structure of thanatin, a potent bactericidal and fungicidal insect peptide, determined from proton two-dimensional nuclear magnetic resonance data
103. Structure-activity analysis of brevinin 1E amide, an antimicrobial peptide from Rana esculenta
104. Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes
105. Marked increase in membranolytic selectivity of novel cyclic tachyplesins constrained with an antiparallel two-beta strand cystine framework
106. Antimicrobial peptides in insects; structure and function
107. Expression of the α-thionin gene from barley in tobacco confers enhanced resistance to bacterial pathogens
108. Expression of cecropin B lytic peptide analog in transgenic tobacco confers enhanced resistance to bacterial wilt caused by Pseudomonas solanacearum
109. Selective inhibition of cecropin-like activity of insect immune blood by protease from American foulbrood scales
110. Active resistance of entomophagous rhabditid Heterorhabditis bacteriophora to insect immunity
111. Identification of immune inhibitor from Pseudomonas aeruginosa of inducible cell-free antibacterial activity in insects
112. Characterization of inhibitor A, a protease from Bacillus thuringiensis which degrades attacins and cecropins, two classes of antibacterial proteins in insects
113. A single amino acid substitution in the antimicrobial defense protein cecropin B is associated with diminished degradation by leaf intercellular fluid
114. Cecropin A-derived peptides are potent inhibitors of fungal plant pathogens
115. Peptide stability in drug development: A comparison of peptide reactivity in different biological media
116. Peptide stability in drug development. II. Effect of single amino acid substitution and glycosylation on peptide reactivity in human serum
117. A repertoire of novel antibacterial diastereomeric peptides with selective cytolytic activity
118. Synthesis of novel unnatural amino acid as a building block and its incorporation into an antimicrobial peptide
119. Synthesis and antibacterial action of cecropin and proline-argininerich peptides from pig Intestine
120. Design, synthesis and characterization of antimicrobial pseudopeptides corresponding to membrane-active peptide
121. Preliminary experimental anticancer activity of cecropins
122. Expression of antimicrobial peptides has an antitumour effect in human cells
123. Retro and retroenantio analogs of cecropin-melittin hybrids
124. Antimicrobial peptides protect coho salmon from Vibrio anguillarum infections
125. Antibiotic resistance found in wild rodents