Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 3, 2013, Pages 1004-1012

  Ilić, Nada ^a   Novković, Mario ^a   Guida, Filomena ^b   Xhindoli, Daniela ^b   Benincasa, Monica ^b   Tossi, Alessandro ^b   Juretić, Davor ^a  

^a UNIVERSITY OF SPLIT   (Croatia)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Antimicrobial peptide; Helical peptide; Membranolytic; Selectivity index

Indexed keywords

ADEPANTIN 1; ADEPANTIN 2; ADEPANTIN 3; ADEPANTIN DERIVATIVE; ASCAPHIN 1; GLYCINE; LYSINE; POLYPEPTIDE ANTIBIOTIC AGENT; PSEUDIN 2; UNCLASSIFIED DRUG;

ALGORITHM; AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ANTIMICROBIAL SELECTIVITY INDEX; ANURA; ARTICLE; ARTIFICIAL MEMBRANE; BACTERIAL STRAIN; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; DRUG CONCENTRATION; DRUG CYTOTOXICITY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; HEMOLYSIS; HOST CELL; HUMAN; HUMAN CELL; HYDROPHOBICITY; KLEBSIELLA PNEUMONIAE; MINIMUM BACTERICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; ANURA; BASE SEQUENCE; CIRCULAR DICHROISM; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ERYTHROCYTES; ESCHERICHIA COLI; GLYCINE; HUMANS; LIPOSOMES; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES; TIME FACTORS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; NEGIBACTERIA;

EID: 84872106766     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.11.017     Document Type: Article

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