메뉴 건너뛰기




Volumn 28, Issue 4, 2012, Pages 1362-1368

Suppression of tumor invasion and migration in breast cancer cells following delivery of siRNA against Stat3 with the antimicrobial peptide PR39

Author keywords

Antimicrobial peptide; Matrix matalloproteinase 9; Porcine cathelicidin; Signal transducers and activators of transcription 3; siRNA

Indexed keywords

LIPOFECTAMINE; PR 39; SMALL INTERFERING RNA; STAT3 PROTEIN;

EID: 84866467316     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1911     Document Type: Article
Times cited : (30)

References (33)
  • 1
    • 84866446218 scopus 로고    scopus 로고
    • Sniper the hyperplasia of mammary glands and escort for the women health
    • Yang SY: Sniper the hyperplasia of mammary glands and escort for the women health. Med People: 34-35, 2007.
    • (2007) Med People , pp. 34-35
    • Yang, S.Y.1
  • 2
    • 36549037548 scopus 로고    scopus 로고
    • Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells
    • Jun JY, Griffith JW, Bruggeman R, et al: Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. Breast Cancer Res Treat 107: 33-40, 2008.
    • (2008) Breast Cancer Res Treat , vol.107 , pp. 33-40
    • Jun, J.Y.1    Griffith, J.W.2    Bruggeman, R.3
  • 3
    • 0031443156 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells
    • Garcia R, Yu CL, Hudnall A, et al: Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells. Cell Growth Differ 8: 1267-1276, 1997.
    • (1997) Cell Growth Differ , vol.8 , pp. 1267-1276
    • Garcia, R.1    Yu, C.L.2    Hudnall, A.3
  • 4
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer - New molecular targets come of age
    • Yu H and Jove R: The STATs of cancer - new molecular targets come of age. Nat Rev Cancer 4: 97-105, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 5
    • 34247600538 scopus 로고    scopus 로고
    • STAT3 as a central mediator of neoplastic cellular transformation
    • Frank DA: STAT3 as a central mediator of neoplastic cellular transformation. Cancer Lett 251: 199-210, 2007.
    • (2007) Cancer Lett , vol.251 , pp. 199-210
    • Frank, D.A.1
  • 6
    • 0036782706 scopus 로고    scopus 로고
    • Transcription factors as targets for cancer therapy
    • Darnell JE Jr: Transcription factors as targets for cancer therapy. Nat Rev Cancer 2: 740-749, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 740-749
    • Darnell Jr., J.E.1
  • 7
    • 79960393173 scopus 로고    scopus 로고
    • Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition
    • Chiu WT, Lee HT, Huang FJ, et al: Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition. Cancer Res 71: 4932-4943, 2011.
    • (2011) Cancer Res , vol.71 , pp. 4932-4943
    • Chiu, W.T.1    Lee, H.T.2    Huang, F.J.3
  • 8
    • 0037444373 scopus 로고    scopus 로고
    • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
    • Blaskovich MA, Sun J, Cantor A, et al: Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Res 63: 1270-1279, 2003.
    • (2003) Cancer Res , vol.63 , pp. 1270-1279
    • Blaskovich, M.A.1    Sun, J.2    Cantor, A.3
  • 9
    • 0037386568 scopus 로고    scopus 로고
    • Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth
    • Leong PL, Andrews GA, Johnson DE, et al: Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth. Proc Natl Acad Sci USA 100: 4138-4143, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4138-4143
    • Leong, P.L.1    Andrews, G.A.2    Johnson, D.E.3
  • 10
    • 13344295097 scopus 로고    scopus 로고
    • Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
    • Meydan N, Grunberger T, Dadi H, et al: Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature 379: 645-648, 1996.
    • (1996) Nature , vol.379 , pp. 645-648
    • Meydan, N.1    Grunberger, T.2    Dadi, H.3
  • 11
    • 0037112367 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
    • Mora LB, Buettner R, Seigne J, et al: Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res 62: 6659-6666, 2002.
    • (2002) Cancer Res , vol.62 , pp. 6659-6666
    • Mora, L.B.1    Buettner, R.2    Seigne, J.3
  • 12
    • 8944251628 scopus 로고    scopus 로고
    • A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells
    • Nakajima K, Yamanaka Y, Nakae K, et al: A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J 15: 3651-3658, 1996.
    • (1996) EMBO J , vol.15 , pp. 3651-3658
    • Nakajima, K.1    Yamanaka, Y.2    Nakae, K.3
  • 13
    • 0034163461 scopus 로고    scopus 로고
    • Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells
    • Ni Z, Lou W, Leman ES, et al: Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells. Cancer Res 60: 1225-1228, 2000.
    • (2000) Cancer Res , vol.60 , pp. 1225-1228
    • Ni, Z.1    Lou, W.2    Leman, E.S.3
  • 15
    • 34248672837 scopus 로고    scopus 로고
    • Toxicogenomics of non-viral drug delivery systems for RNAi: Potential impact on siRNA-mediated gene silencing activity and specificity
    • Akhtar S and Benter I: Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity. Adv Drug Deliv Rev 59: 164-182, 2007.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 164-182
    • Akhtar, S.1    Benter, I.2
  • 16
    • 33751099034 scopus 로고    scopus 로고
    • RNAi therapeutics: A potential new class of pharmaceutical drugs
    • Bumcrot D, Manoharan M, Koteliansky V and Sah DW: RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat Chem Biol 2: 711-719, 2006.
    • (2006) Nat Chem Biol , vol.2 , pp. 711-719
    • Bumcrot, D.1    Manoharan, M.2    Koteliansky, V.3    Sah, D.W.4
  • 17
    • 34248644581 scopus 로고    scopus 로고
    • Octaarginine-modified multifunctional envelope-type nano device for siRNA
    • Nakamura Y, Kogure K, Futaki S and Harashima H: Octaarginine-modified multifunctional envelope-type nano device for siRNA. J Control Release 119: 360-367, 2007.
    • (2007) J Control Release , vol.119 , pp. 360-367
    • Nakamura, Y.1    Kogure, K.2    Futaki, S.3    Harashima, H.4
  • 18
    • 0026349223 scopus 로고
    • Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides
    • Agerberth B, Lee JY, Bergman T, et al: Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem 202: 849-854, 1991.
    • (1991) Eur J Biochem , vol.202 , pp. 849-854
    • Agerberth, B.1    Lee, J.Y.2    Bergman, T.3
  • 19
    • 0027216093 scopus 로고
    • Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine
    • Boman HG, Agerberth B and Boman A: Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine. Infect Immun 61: 2978-2984, 1993.
    • (1993) Infect Immun , vol.61 , pp. 2978-2984
    • Boman, H.G.1    Agerberth, B.2    Boman, A.3
  • 20
    • 0027453329 scopus 로고
    • A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39
    • Storici P and Zanetti M: A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39. Biochem Biophys Res Commun 196: 1058-1065, 1993.
    • (1993) Biochem Biophys Res Commun , vol.196 , pp. 1058-1065
    • Storici, P.1    Zanetti, M.2
  • 21
    • 0029664907 scopus 로고    scopus 로고
    • PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47phox
    • Shi J, Ross CR, Leto TL and Blecha F: PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47phox. Proc Nat Acad Sci USA 93: 6014-6018, 1996.
    • (1996) Proc Nat Acad Sci USA , vol.93 , pp. 6014-6018
    • Shi, J.1    Ross, C.R.2    Leto, T.L.3    Blecha, F.4
  • 22
    • 0032582684 scopus 로고    scopus 로고
    • PR-39, a syndecan-inducing antimicrobial peptide, binds and affects p130(Cas)
    • Chan YR and Gallo RL: PR-39, a syndecan-inducing antimicrobial peptide, binds and affects p130(Cas). J Biol Chem 273: 28978-28985, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 28978-28985
    • Chan, Y.R.1    Gallo, R.L.2
  • 23
    • 0033847049 scopus 로고    scopus 로고
    • Inhibition of ubiquitin-proteasome pathway-mediated i kappa B alpha degradation by a naturally occurring antibacterial peptide
    • Gao Y, Lecker S, Post MJ, et al: Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide. J Clin Invest 106: 439-448, 2000.
    • (2000) J Clin Invest , vol.106 , pp. 439-448
    • Gao, Y.1    Lecker, S.2    Post, M.J.3
  • 24
    • 72149101228 scopus 로고    scopus 로고
    • The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine
    • Alshamsan A, Hamdy S, Samuel J, et al: The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine. Biomaterials 31: 1420-1428, 2010.
    • (2010) Biomaterials , vol.31 , pp. 1420-1428
    • Alshamsan, A.1    Hamdy, S.2    Samuel, J.3
  • 25
    • 78149432945 scopus 로고    scopus 로고
    • Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis
    • Ye Y, Yin DT, Chen L, et al: Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis. PLoS One 5: e13406, 2010.
    • (2010) PLoS One , vol.5
    • Ye, Y.1    Yin, D.T.2    Chen, L.3
  • 26
    • 0032875198 scopus 로고    scopus 로고
    • Proline-rich antimicrobial peptide, PR39 gene transduction altered invasive activity and actin structure in human hepatocellular carcinoma cells
    • Ohtake T, Fujimoto Y, Ikuta K, et al: Proline-rich antimicrobial peptide, PR39 gene transduction altered invasive activity and actin structure in human hepatocellular carcinoma cells. Br J Cancer 81: 393-403, 1999.
    • (1999) Br J Cancer , vol.81 , pp. 393-403
    • Ohtake, T.1    Fujimoto, Y.2    Ikuta, K.3
  • 28
    • 33745187338 scopus 로고    scopus 로고
    • Arginine-rich intracellular delivery peptides noncovalently transport protein into living cells
    • Wang YH, Chen CP, Chan MH, et al: Arginine-rich intracellular delivery peptides noncovalently transport protein into living cells. Biochem Biophys Res Commun 346: 758-767, 2006.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 758-767
    • Wang, Y.H.1    Chen, C.P.2    Chan, M.H.3
  • 29
    • 34247605933 scopus 로고    scopus 로고
    • An intracellular delivery method for siRNA by an arginine-rich peptide
    • Wang YH, Hou YW and Lee HJ: An intracellular delivery method for siRNA by an arginine-rich peptide. J Biochem Biophys Methods 70: 579-586, 2007.
    • (2007) J Biochem Biophys Methods , vol.70 , pp. 579-586
    • Wang, Y.H.1    Hou, Y.W.2    Lee, H.J.3
  • 30
    • 77952241478 scopus 로고    scopus 로고
    • RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system
    • Kim SW, Kim NY, Choi YB, et al: RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system. J Control Release 143: 335-343, 2010.
    • (2010) J Control Release , vol.143 , pp. 335-343
    • Kim, S.W.1    Kim, N.Y.2    Choi, Y.B.3
  • 31
    • 77958124580 scopus 로고    scopus 로고
    • Dual functions of the human antimicrobial peptide LL-37-target membrane perturbation and host cell cargo delivery
    • Zhang X, Oglecka K, Sandgren S, et al: Dual functions of the human antimicrobial peptide LL-37-target membrane perturbation and host cell cargo delivery. Biochim Biophys Acta 1798: 2201-2208, 2010.
    • (2010) Biochim Biophys Acta , vol.1798 , pp. 2201-2208
    • Zhang, X.1    Oglecka, K.2    Sandgren, S.3
  • 32
    • 38349009178 scopus 로고    scopus 로고
    • Studies on anticancer activities of antimicrobial peptides
    • Hoskin DW and Ramamoorthy A: Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta 1778: 357-375, 2008.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 357-375
    • Hoskin, D.W.1    Ramamoorthy, A.2
  • 33
    • 33845873577 scopus 로고    scopus 로고
    • Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: Quantitative analysis of uptake and biological effect
    • Veldhoen S, Laufer SD, Trampe A and Restle T: Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: quantitative analysis of uptake and biological effect. Nucleic Acids Res 34: 6561-6573, 2006.
    • (2006) Nucleic Acids Res , vol.34 , pp. 6561-6573
    • Veldhoen, S.1    Laufer, S.D.2    Trampe, A.3    Restle, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.