Syk and src family kinases regulate c-type lectin receptor 2 (clec-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells

Journal of Biological Chemistry

Volumn 289, Issue 52, 2014, Pages 35695-35710

  Pollitt, Alice Y ^a   Poulter, Natalie S ^a   Gitz, Eelo ^a,b   Navarro Nuñez, Leyre ^a   Wang, Ying Jie ^c   Hughes, Craig E ^a   Thomas, Steven G ^a   Nieswandt, Bernhard ^d   Douglas, Michael R ^a,e   Owen, Dylan M ^f   Jackson, David G ^c   Dustin, Michael L ^g,h   Watson, Steve P ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e DUDLEY GROUP OF HOSPITALS NHS TRUST   (United Kingdom)

^f KING'S COLLEGE LONDON   (United Kingdom)

^g UNIVERSITY OF OXFORD   (United Kingdom)

^h NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; AMINO ACIDS; ENDOTHELIAL CELLS; ENZYMES; INDIUM PLATING; LIPID BILAYERS; PLATELETS; PROTEINS; SIGNALING; STOCHASTIC SYSTEMS;

FLUORESCENCE LIFETIME IMAGING; OPTICAL RECONSTRUCTION; PLATELET ADHESION; SIGNALING EVENTS; SINGLE STRUCTURE; SRC-FAMILY KINASE; SUPPORTED LIPID BILAYERS; TYROSINE KINASE;

CELL SIGNALING;

C TYPE LECTIN RECEPTOR 2 PROTEIN; LECTIN RECEPTOR; PODOPLANIN; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; CLEC-2 PROTEIN, MOUSE; GP38 PROTEIN, MOUSE; LECTIN; MEMBRANE PROTEIN; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE ANALYSIS; INTRACELLULAR SIGNALING; LIPID BILAYER; LYMPH VESSEL ENDOTHELIUM; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; THROMBOCYTE ADHESION; ANIMAL; C57BL MOUSE; CELL ADHESION; CELL CULTURE; CELL MEMBRANE; CYTOLOGY; HEK293 CELL LINE; HUMAN; LYMPHOID TISSUE; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; CELL ADHESION; CELL MEMBRANE; CELLS, CULTURED; ENDOTHELIAL CELLS; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; LYMPHOID TISSUE; MEMBRANE GLYCOPROTEINS; MICE, INBRED C57BL; MICE, TRANSGENIC; PLATELET ADHESIVENESS; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84919884369     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.584284     Document Type: Article

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