The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets

Blood

Volumn 125, Issue 1, 2015, Pages 144-154

  Hughes, Craig E ^a   Finney, Brenda A ^a   Koentgen, Frank ^b   Lowe, Kate L ^a   Watson, Steve P ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b Ozgene Pty Ltd   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CRE RECOMBINASE; FIBRINOGEN; INTEGRIN; LAT PROTEIN; PROTEIN KINASE SYK; CLEC-2 PROTEIN, MOUSE; FIBRINOGEN RECEPTOR; LECTIN; PHOSPHOPROTEIN; PHOSPHOTYROSINE; PLATELET MEMBRANE GLYCOPROTEIN VI; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; AUTOPHOSPHORYLATION; BLOOD CLOT RETRACTION; CELL LINEAGE; COMPARATIVE STUDY; CONTROLLED STUDY; INTRACELLULAR SIGNALING; LOXP SITE; LYMPH VESSEL; MEGAKARYOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTOPOIESIS; VASCULARIZATION; VEIN ANASTOMOSIS; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; DRUG EFFECTS; GENETICS; IDIOPATHIC THROMBOCYTOPENIC PURPURA; METABOLISM; PHOSPHORYLATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; TRANSGENIC MOUSE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BLOOD PLATELETS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MICE; MICE, TRANSGENIC; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTYROSINE; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

EID: 84919911314     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-05-579375     Document Type: Article

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