Clinical significance of ABCA2, a possible molecular marker for oligodendrogliomas

Neurosurgery

Volumn 60, Issue 4, 2007, Pages 707-714

  Soichi, Obara ^a   Masanori, Nakata ^b   Hideo, Takeshima ^c   Kazunori, Arita ^a   Nobuya, Inagaki ^d   Jun Ichi, Kuratsu ^c  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

ABCA2; Adenosine triphosphate binding cassette transporter; Glioma; Olig2; Oligodendroglioma

Indexed keywords

ABC TRANSPORTER A2; ADENOSINE TRIPHOSPHATE DERIVATIVE; MESSENGER RNA; MOLECULAR MARKER; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA; CONTROLLED STUDY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; OLIGODENDROGLIOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL;

ATP-BINDING CASSETTE TRANSPORTERS; BRAIN NEOPLASMS; FEASIBILITY STUDIES; HUMANS; NEOPLASM PROTEINS; OLIGODENDROGLIOMA; TUMOR MARKERS, BIOLOGICAL;

EID: 34147201741     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000255395.15657.06     Document Type: Article

References (26)

1. Alaminos M, Davalos V, Ropero S, Setien F, Paz MF, Herranz M, Fraga MF, Mora J, Cheung NK, Gerald WL, Esteller M: EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma. Cancer Res 65:2565-2571, 2005.
2. Barbashina V, Salazar P, Holland EC, Rosenblum MK, Ladanyi M: Allelic losses at 1p36 and 19q13 in gliomas: Correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene. Clin Cancer Res 11:1119-1128, 2005.
3. Bigner SH, Rasheed BK, Wiltshire R, McLendon RE: Morphologic and molecular genetic aspects of oligodendroglial neoplasms. Neuro-oncol 1:52-60, 1999.
4. Boonstra R, Timmer-Bosscha H, van Echten-Arends J, van der Kolk DM, van den Berg A, de Jong B, Tew KD, Poppema S, de Vries EG: Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation. Br J Cancer 90:2411-2417, 2004.
5. Cairncross JG, Ueki K, Zlatescu MC, Lisle DK, Finkelstein DM, Hammond RR, Silver JS, Stark PC, Macdonald DR, Ino Y, Ramsay DA, Louis DN: Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 90:1473-1479, 1998.
6. Cruz-Sanchez FF, Rossi ML, Buller JR, Carboni P Jr, Fineron PW, Coakham HB: Oligodendrogliomas: A clinical, histological, immunocytochemical and lectin-binding study. Histopathology 19:361-367, 1991.
7. Higgins CF: ABC transporters: From microorganisms to man. Annu Rev Cell Biol 8:67-113, 1992.
8. Hoang-Xuan K, Aguirre-Cruz L, Mokhtari K, Marie Y, Sanson M: OLIG-1 and 2 gene expression and oligodendroglial tumours. Neuropathol Appl Neurobiol 28:89-94, 2002.
9. Hokama Y, Tanaka J, Nakamura H, Hori T: MBP and GFAP immunohistochemistry of oligodendrogliomas with relationship to myelin-forming glia in cell differentiation [in Japanese]. No To Shinkei 38:379-386, 1986.
10. Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK: The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 61:215-229, 2002.
11. Landry CF, Verity MA, Cherman L, Kashima T, Black K, Yates A, Campagnoni AT: Expression of oligodendrocytic mRNAs in glial tumors: Changes associated with tumor grade and extent of neoplastic infiltration. Cancer Res 57:4098-4104, 1997.
12. Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH: The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J Neuropathol Exp Neurol 63:499-509, 2004.
13. Lu QR, Park JK, Noll E, Chan JA, Alberta J, Yuk D, Alzamora MG, Louis DN, Stiles CD, Rowitch DH, Black PM: Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. Proc Natl Acad Sci U S A 98:10851-10856, 2001.
14. Mace S, Cousin E, Ricard S, Genin E, Spanakis E, Lafargue-Soubigou C, Genin B, Fournel R, Roche S, Haussy G, Massey F, Soubigou S, Brefort G, Benoit P, Brice A, Campion D, Hollis M, Pradier L, Benavides J, Deleuze JF: ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease. Neurobiol Dis 18:119-25, 2005.
15. Marie Y, Sanson M, Mokhtari K, Leuraud P, Kujas M, Delattre JY, Poirier J, Zalc B, Hoang-Xuan K: OLIG2 as a specific marker of oligodendroglial tumour cells. Lancet 358:298-300, 2001.
16. van den Bent M, Chinot OL, Cairncross JG: Recent developments in the molecular characterization and treatment of oligodendroglial tumors. Neurooncol 5:128-138, 2003.
17. Nakagawa Y, Perentes E, Rubinstein LJ: Immunohistochemical characterization of oligodendrogliomas: An analysis of multiple markers. Acta Neuropathol (Berl) 72:15-22, 1986.
18. Nutt CL, Mani DR, Betensky RA, Tamayo P, Cairncross JG, Ladd C, Pohl U, Hartmann C, McLaughlin ME, Batchelor TT, Black PM, von Deimling A, Pomeroy SL, Golub TR, Louis DN: Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res 63:1602-1607, 2003.
19. Ohnishi A, Sawa H, Tsuda M, Sawamura Y, Itoh T, Iwasaki Y, Nagashima K: Expression of the oligodendroglial lineage-associated markers Olig1 and Olig2 in different types of human gliomas. J Neuropathol Exp Neurol 62:1052-1059, 2003.
20. Pohl U, Cairncross JG, Louis DN: Homozygous deletions of the CDKN2C/p18INK4C gene on the short arm of chromosome 1 in anaplastic oligodendrogliomas. Brain Pathol 9:639-643, 1999.
21. Riemenschneider MJ, Koy TH, Reifenberger G: Expression of oligodendrocyte lineage genes in oligodendroglial and astrocytic gliomas. Acta Neuropathol (Berl) 107:277-282, 2004.
22. Schmitz G, Kaminski WE: ABCA2: A candidate regular of neural transmembrane lipid transport. Cell Mol Life Sci 59:1285-1295, 2002.
23. Wang Y, Yamada K, Tanaka Y, Ishikawa K, Inagaki N: Expression of ABCA2 protein in human vestibular schwannoma and peripheral nerve. J Neurol Sci 232:59-63, 2005.
24. Zhao LX, Zhou CJ, Tanaka A, Nakata M, Hirabayashi T, Amachi T, Shioda S, Ueda K, Inagaki N: Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2. Biochem J 350:865-872, 2000.
25. Zhou C, Zhao L, Inagaki N, Guan J, Nakajo S, Hirabayashi T, Kikuyama S, Shioda S: Atp-binding cassette transporter ABC2/ABCA2 in the rat brain: A novel mammalian lysosome-associated membrane protein and a specific marker for a specific marker for oligodendrocytes but not for myelin sheaths. J Neurosci 21:849-857, 2001.
26. Zhou CJ, Inagaki N, Pleasure SJ, Zhao LX, Kikuyama S, Shioda S: ATPbinding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination. J Comp Neurol 451:334-345, 2002.