-
1
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X et al (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
2
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G et al (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360:765-773
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
-
3
-
-
77954697566
-
Isocitrate dehydrogenase 1 and 2 mutations in cancer: Alterations at a crossroads of cellular metabolism
-
Reitman ZJ, Yan H (2010) Isocitrate dehydrogenase 1 and 2 mutations in cancer: Alterations at a crossroads of cellular metabolism. J Natl Cancer Inst 102:932-941
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 932-941
-
-
Reitman, Z.J.1
Yan, H.2
-
4
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, von Deimling A (2008) Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol 116:597-602
-
(2008)
Acta Neuropathol
, vol.116
, pp. 597-602
-
-
Balss, J.1
Meyer, J.2
Mueller, W.3
Korshunov, A.4
Hartmann, C.5
Von Deimling, A.6
-
5
-
-
79958136272
-
DM et al (2011) Adult grade II diffuse astrocytomas are genetically distinct from and more aggressive than their paediatric counterparts
-
Pearson
-
Jones DT, Mulholland SA, Pearson DM et al (2011) Adult grade II diffuse astrocytomas are genetically distinct from and more aggressive than their paediatric counterparts. Acta Neuropathol 121:753-761
-
Acta Neuropathol
, vol.121
, pp. 753-761
-
-
Jones, D.T.1
Mulholland, S.A.2
-
6
-
-
68349116524
-
IDH1 mutations are present in the majority of common adult gliomas but are rare in primary glioblastomas
-
Ichimura K, Pearson DM, Kocialkowski S et al (2009) IDH1 mutations are present in the majority of common adult gliomas but are rare in primary glioblastomas. Neuro Oncol 11:341-347
-
(2009)
Neuro Oncol
, vol.11
, pp. 341-347
-
-
Ichimura, K.1
Pearson, D.M.2
Kocialkowski, S.3
-
7
-
-
68349088073
-
Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma
-
Korshunov A, Meyer J, Capper D et al (2009) Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma. Acta Neuropathol 118: 401-405
-
(2009)
Acta Neuropathol
, vol.118
, pp. 401-405
-
-
Korshunov, A.1
Meyer, J.2
Capper, D.3
-
8
-
-
75449119103
-
Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms
-
Green A, Beer P (2010) Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms. N Engl J Med 362:369-370
-
(2010)
N Engl J Med
, vol.362
, pp. 369-370
-
-
Green, A.1
Beer, P.2
-
9
-
-
77952426827
-
Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms
-
Kosmider O, Gelsi-Boyer V, Slama L et al (2010) Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms. Leukemia 24:1094-1096
-
(2010)
Leukemia
, vol.24
, pp. 1094-1096
-
-
Kosmider, O.1
Gelsi-Boyer, V.2
Slama, L.3
-
10
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ et al (2009) Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 361:1058-1066
-
(2009)
N Engl J Med
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
-
11
-
-
79958226901
-
IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours
-
Amary MF, Bacsi K, Maggiani F et al (2011) IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours. J Pathol 224:334-343
-
(2011)
J Pathol
, vol.224
, pp. 334-343
-
-
Amary, M.F.1
Bacsi, K.2
Maggiani, F.3
-
12
-
-
82255183051
-
Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
-
Amary MF, Damato S, Halai D et al (2011) Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2. Nat Genet 43:1262-1265
-
Nat Genet
, vol.43
, pp. 1262-1265
-
-
Amary, M.F.1
Damato, S.2
Halai, D.3
-
13
-
-
82255183048
-
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
-
Pansuriya TC, van Eijk R, d'Adamo P et al (2011) Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat Genet 43:1256-1261
-
(2011)
Nat Genet
, vol.43
, pp. 1256-1261
-
-
Pansuriya, T.C.1
Van Eijk, R.2
D'Adamo, P.3
-
14
-
-
58349111311
-
IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors
-
Bleeker FE, Lamba S, Leenstra S et al (2009) IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat 30:7-11
-
(2009)
Hum Mutat
, vol.30
, pp. 7-11
-
-
Bleeker, F.E.1
Lamba, S.2
Leenstra, S.3
-
15
-
-
67449099808
-
Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers
-
Kang MR, Kim MS, Oh JE et al (2009) Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers. Int J Cancer 125:353-355
-
(2009)
Int J Cancer
, vol.125
, pp. 353-355
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
-
16
-
-
79952769109
-
Mutant IDH1 confers an in vivo growth in a melanoma cell line with BRAF mutation
-
Shibata T, Kokubu A, Miyamoto M, Sasajima Y, Yamazaki N (2011) Mutant IDH1 confers an in vivo growth in a melanoma cell line with BRAF mutation. Am J Pathol 178:1395-1402
-
(2011)
Am J Pathol
, vol.178
, pp. 1395-1402
-
-
Shibata, T.1
Kokubu, A.2
Miyamoto, M.3
Sasajima, Y.4
Yamazaki, N.5
-
17
-
-
78649990315
-
Cancer-associated IDH mutations: Biomarker and therapeutic opportunities
-
Yen KE, Bittinger MA, Su SM, Fantin VR (2010) Cancer-associated IDH mutations: Biomarker and therapeutic opportunities. Oncogene 29:6409-6417
-
(2010)
Oncogene
, vol.29
, pp. 6409-6417
-
-
Yen, K.E.1
Bittinger, M.A.2
Su, S.M.3
Fantin, V.R.4
-
18
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas
-
Hartmann C, Meyer J, Balss J et al (2009) Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas. Acta Neuropathol 118:469-474
-
(2009)
Acta Neuropathol
, vol.118
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
-
19
-
-
80055100987
-
Glioma IDH1 mutation patterns off the beaten track
-
Pusch S, Sahm F, Meyer J, Mittelbronn M, Hartmann C, von Deimling A (2011) Glioma IDH1 mutation patterns off the beaten track. Neuropathol Appl Neurobiol 37:428-430
-
(2011)
Neuropathol Appl Neurobiol
, vol.37
, pp. 428-430
-
-
Pusch, S.1
Sahm, F.2
Meyer, J.3
Mittelbronn, M.4
Hartmann, C.5
Von Deimling, A.6
-
20
-
-
78651082266
-
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
-
Hartmann C, Hentschel B, Wick W et al (2010) Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas. Acta Neuropathol 120:707-718
-
(2010)
Acta Neuropathol
, vol.120
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
-
21
-
-
33750563258
-
A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma
-
DOI 10.1158/0008-5472.CAN-06-1796
-
Jenkins RB, Blair H, Ballman KV et al (2006) A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res 66:9852-9861 (Pubitemid 44672036)
-
(2006)
Cancer Research
, vol.66
, Issue.20
, pp. 9852-9861
-
-
Jenkins, R.B.1
Blair, H.2
Ballman, K.V.3
Giannini, C.4
Arusell, R.M.5
Law, M.6
Flynn, H.7
Passe, S.8
Felten, S.9
Brown, P.D.10
Shaw, E.G.11
Buckner, J.C.12
-
22
-
-
80052713548
-
Genetic profile of astrocytic and oligodendroglial gliomas
-
Ohgaki H, Kleihues P (2011) Genetic profile of astrocytic and oligodendroglial gliomas. Brain Tumor Pathol 28:177- 183
-
(2011)
Brain Tumor Pathol
, vol.28
, pp. 177-183
-
-
Ohgaki, H.1
Kleihues, P.2
-
23
-
-
65349150503
-
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
-
Watanabe T, Nobusawa S, Kleihues P, Ohgaki H (2009) IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol 174:1149-1153
-
(2009)
Am J Pathol
, vol.174
, pp. 1149-1153
-
-
Watanabe, T.1
Nobusawa, S.2
Kleihues, P.3
Ohgaki, H.4
-
24
-
-
64849098267
-
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF- 1alpha
-
Zhao S, Lin Y, Xu W et al (2009) Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF- 1alpha. Science 324:261-265
-
(2009)
Science
, vol.324
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
-
25
-
-
79951542753
-
2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations
-
Jin G, Reitman ZJ, Spasojevic I et al (2011) 2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations. PLoS ONE 6:e16812
-
PLoS ONE
, vol.6
-
-
Jin, G.1
Reitman, Z.J.2
Spasojevic, I.3
-
26
-
-
77953702324
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S et al (2009) Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 465:966
-
(2009)
Nature
, vol.465
, pp. 966
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
27
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutaratedependent dioxygenases
-
Xu W, Yang H, Liu Y et al (2011) Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutaratedependent dioxygenases. Cancer Cell 19:17-30
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
-
28
-
-
79451471184
-
R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1alpha upregulation in adult glioma
-
Williams SC, Karajannis MA, Chiriboga L, Golfinos JG, von Deimling A, Zagzag D (2011) R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1alpha upregulation in adult glioma. Acta Neuropathol 121:279-281
-
(2011)
Acta Neuropathol
, vol.121
, pp. 279-281
-
-
Williams, S.C.1
Karajannis, M.A.2
Chiriboga, L.3
Golfinos, J.G.4
Von Deimling, A.5
Zagzag, D.6
-
29
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr H, Weisenberger DJ, Diefes K et al (2010) Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17:510-522
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
-
30
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa ME, Abdel-Wahab O, Lu C et al (2010) Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18:553-567
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
-
31
-
-
84858796263
-
-
Epub ahead of print
-
Turcan S, Rohle D, Goenka A et al (2012) IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature Epub ahead of print
-
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
-
32
-
-
84858796262
-
-
Epub ahead of print
-
Lu C, Ward PS, Kapoor GS et al (2012) IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature Epub ahead of print
-
-
-
Lu, C.1
Ward, P.S.2
Kapoor, G.S.3
-
33
-
-
57349166553
-
Hydroxyglutaric aciduria and malignant brain tumor: A case report and literature review
-
Aghili M, Zahedi F, Rafiee E (2009) Hydroxyglutaric aciduria and malignant brain tumor: A case report and literature review. J Neurooncol 91:233-236
-
(2009)
J Neurooncol
, vol.91
, pp. 233-236
-
-
Aghili, M.1
Zahedi, F.2
Rafiee, E.3
-
34
-
-
79956372800
-
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
-
Krell D, Assoku M, Galloway M, Mulholland P, Tomlinson I, Bardella C (2011) Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. PLoS ONE 6:e19868
-
PLoS ONE
, vol.6
-
-
Krell, D.1
Assoku, M.2
Galloway, M.3
Mulholland, P.4
Tomlinson, I.5
Bardella, C.6
-
35
-
-
79951790557
-
Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations
-
Brehmer S, Pusch S, Schmieder K, von Deimling A, Hartmann C (2011) Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations. Neuropathol Appl Neurobiol 37:330-332
-
(2011)
Neuropathol Appl Neurobiol
, vol.37
, pp. 330-332
-
-
Brehmer, S.1
Pusch, S.2
Schmieder, K.3
Von Deimling, A.4
Hartmann, C.5
-
36
-
-
84255200412
-
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations
-
Jin SG, Jiang Y, Qiu R et al (2011) 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res 71:7360-7365
-
(2011)
Cancer Res
, vol.71
, pp. 7360-7365
-
-
Jin, S.G.1
Jiang, Y.2
Qiu, R.3
-
37
-
-
80053215336
-
TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations
-
Kim YH, Pierscianek D, Mittelbronn M et al (2011) TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations. J Clin Pathol 64:850-852
-
(2011)
J Clin Pathol
, vol.64
, pp. 850-852
-
-
Kim, Y.H.1
Pierscianek, D.2
Mittelbronn, M.3
-
38
-
-
34848815312
-
The pivotal role of astrocytes in the metabolism of iron in the brain
-
DOI 10.1007/s11064-007-9375-0
-
Dringen R, Bishop GM, Koeppe M, Dang TN, Robinson SR (2007) The pivotal role of astrocytes in the metabolism of iron in the brain. Neurochem Res 32:1884-1890 (Pubitemid 47497889)
-
(2007)
Neurochemical Research
, vol.32
, Issue.11
, pp. 1884-1890
-
-
Dringen, R.1
Bishop, G.M.2
Koeppe, M.3
Dang, T.N.4
Robinson, S.R.5
-
39
-
-
56349145099
-
Oxidative stress hypothesis in Alzheimer's disease: A reappraisal
-
Pratico D (2008) Oxidative stress hypothesis in Alzheimer's disease: A reappraisal. Trends Pharmacol Sci 29:609-615
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 609-615
-
-
Pratico, D.1
-
40
-
-
58949084649
-
Base excision repair of oxidative DNA damage and association with cancer and aging
-
Maynard S, Schurman SH, Harboe C, de Souza-Pinto NC, Bohr VA (2009) Base excision repair of oxidative DNA damage and association with cancer and aging. Carcinogenesis 30:2-10
-
(2009)
Carcinogenesis
, vol.30
, pp. 2-10
-
-
Maynard, S.1
Schurman, S.H.2
Harboe, C.3
De Souza-Pinto, N.C.4
Bohr, V.A.5
-
41
-
-
0037733975
-
The importance of glutathione in human disease
-
DOI 10.1016/S0753-3322(03)00043-X
-
Townsend DM, Tew KD, Tapiero H (2003) The importance of glutathione in human disease. Biomed Pharmacother 57:145-155 (Pubitemid 36740460)
-
(2003)
Biomedicine and Pharmacotherapy
, vol.57
, Issue.3
, pp. 145-155
-
-
Townsend, D.M.1
Tew, K.D.2
Tapiero, H.3
-
42
-
-
0036614971
-
+-dependent isocitrate dehydrogenase status modulates oxidative damage to cells
-
DOI 10.1016/S0891-5849(02)00815-8, PII S0891584902008158
-
Lee SM, Koh HJ, Park DC, Song BJ, Huh TL, Park JW (2002) Cytosolic NADP(?)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells. Free Radic Biol Med 32:1185-1196 (Pubitemid 34603355)
-
(2002)
Free Radical Biology and Medicine
, vol.32
, Issue.11
, pp. 1185-1196
-
-
Lee, S.M.1
Koh, H.-J.2
Park, D.-C.3
Song, B.J.4
Huh, T.-L.5
Park, J.-W.6
-
43
-
-
40149108041
-
The tricarboxylic acid cycle, an ancient metabolic network with a novel twist
-
Mailloux RJ, Beriault R, Lemire J et al (2007) The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. PLoS ONE 2:e690
-
(2007)
PLoS ONE
, vol.2
-
-
Mailloux, R.J.1
Beriault, R.2
Lemire, J.3
-
44
-
-
0037361534
-
+-dependent isocitrate dehydrogenase
-
DOI 10.1080/1071576021000050429
-
Kim SY, Park JW (2003) Cellular defense against singlet oxygeninduced oxidative damage by cytosolic NADP?-dependent isocitrate dehydrogenase. Free Radic Res 37:309-316 (Pubitemid 36181887)
-
(2003)
Free Radical Research
, vol.37
, Issue.3
, pp. 309-316
-
-
Kim, S.Y.1
Park, J.-W.2
-
45
-
-
38049115657
-
The mechanism of human nonhomologous DNA end joining
-
Lieber MR (2008) The mechanism of human nonhomologous DNA end joining. J Biol Chem 283:1-5
-
(2008)
J Biol Chem
, vol.283
, pp. 1-5
-
-
Lieber, M.R.1
-
46
-
-
54049088959
-
BCR/ABL promotes accumulation of chromosomal aberrations induced by oxidative and genotoxic stress
-
Koptyra M, Cramer K, Slupianek A, Richardson C, Skorski T (2008) BCR/ABL promotes accumulation of chromosomal aberrations induced by oxidative and genotoxic stress. Leukemia 22:1969-1972
-
(2008)
Leukemia
, vol.22
, pp. 1969-1972
-
-
Koptyra, M.1
Cramer, K.2
Slupianek, A.3
Richardson, C.4
Skorski, T.5
-
47
-
-
84859553853
-
An in vivo patient-derived model of endogenous IDH1-mutant glioma
-
Luchman HA, Stechishin OD, Dang NH et al (2012) An in vivo patient-derived model of endogenous IDH1-mutant glioma. Neuro Oncol 14:184-191
-
(2012)
Neuro Oncol
, vol.14
, pp. 184-191
-
-
Luchman, H.A.1
Stechishin, O.D.2
Dang, N.H.3
-
48
-
-
77649122144
-
IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: A report of the European Organization for Research and Treatment of Cancer Brain Tumor Group
-
van den Bent MJ, Dubbink HJ, Marie Y et al (2010) IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: A report of the European Organization for Research and Treatment of Cancer Brain Tumor Group. Clin Cancer Res 16:1597-1604
-
Clin Cancer Res
, vol.16
, pp. 1597-1604
-
-
Van Den Bent, M.J.1
Dubbink, H.J.2
Marie, Y.3
-
49
-
-
79960315686
-
Molecular markers in low-grade gliomas: Predictive or prognostic?
-
Hartmann C, Hentschel B, Tatagiba M et al (2011) Molecular markers in low-grade gliomas: Predictive or prognostic? Clin Cancer Res 17:4588-4599
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4588-4599
-
-
Hartmann, C.1
Hentschel, B.2
Tatagiba, M.3
-
50
-
-
84872214421
-
-
Mukasa A, Takayanagi S, Saito K et al (2011) Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients. Cancer Sci
-
-
-
Mukasa, A.1
Takayanagi, S.2
Saito, K.3
-
51
-
-
70249097408
-
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
-
Sanson M, Marie Y, Paris S et al (2009) Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 27:4150-4154
-
(2009)
J Clin Oncol
, vol.27
, pp. 4150-4154
-
-
Sanson, M.1
Marie, Y.2
Paris, S.3
-
52
-
-
78149388926
-
Molecular diagnostics of gliomas: The clinical perspective
-
Tabatabai G, Stupp R, van den Bent MJ et al (2010) Molecular diagnostics of gliomas: The clinical perspective. Acta Neuropathol 120:585-592
-
Acta Neuropathol
, vol.120
, pp. 585-592
-
-
Tabatabai, G.1
Stupp, R.2
Van Den Bent, M.J.3
-
53
-
-
83355163405
-
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin
-
Lai A, Kharbanda S, Pope WB et al (2011) Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J Clin Oncol 29:4482-4490
-
(2011)
J Clin Oncol
, vol.29
, pp. 4482-4490
-
-
Lai, A.1
Kharbanda, S.2
Pope, W.B.3
-
54
-
-
70349653793
-
IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
-
Nobusawa S, Watanabe T, Kleihues P, Ohgaki H (2009) IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res 15:6002-6007
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6002-6007
-
-
Nobusawa, S.1
Watanabe, T.2
Kleihues, P.3
Ohgaki, H.4
-
55
-
-
73349109131
-
Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues
-
Horbinski C, Kofler J, Kelly LM, Murdoch GH, Nikiforova MN (2009) Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues. J Neuropathol Exp Neurol 68:1319-1325
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 1319-1325
-
-
Horbinski, C.1
Kofler, J.2
Kelly, L.M.3
Murdoch, G.H.4
Nikiforova, M.N.5
-
56
-
-
79451475068
-
Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology
-
Capper D, Reuss D, Schittenhelm J et al (2011) Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology. Acta Neuropathol 121:241-252
-
(2011)
Acta Neuropathol
, vol.121
, pp. 241-252
-
-
Capper, D.1
Reuss, D.2
Schittenhelm, J.3
-
58
-
-
84855710482
-
-
Andronesi OC, Kim GS, Gerstner E et al (2012) Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy. Sci Transl Med 4:116ra4
-
-
-
Andronesi, O.C.1
Kim, G.S.2
Gerstner, E.3
-
59
-
-
84862776826
-
-
Choi C, Ganji SK, Deberardinis RJ et al (2012) 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDHmutated patients with gliomas. Nat Med
-
-
-
Choi, C.1
Ganji, S.K.2
Deberardinis, R.J.3
-
61
-
-
80052780994
-
Detection of IDH1 mutation in human gliomas: Comparison of immunohistochemistry and sequencing
-
Takano S, Tian W, Matsuda M et al (2011) Detection of IDH1 mutation in human gliomas: Comparison of immunohistochemistry and sequencing. Brain Tumor Pathol 28:115-123
-
(2011)
Brain Tumor Pathol
, vol.28
, pp. 115-123
-
-
Takano, S.1
Tian, W.2
Matsuda, M.3
-
62
-
-
79953024539
-
Establishment of a novel monoclonal antibody SMab-1 specific for IDH1-R132S mutation
-
Kaneko MK, Tian W, Takano S et al (2011) Establishment of a novel monoclonal antibody SMab-1 specific for IDH1-R132S mutation. Biochem Biophys Res Commun 406:608-613
-
(2011)
Biochem Biophys Res Commun
, vol.406
, pp. 608-613
-
-
Kaneko, M.K.1
Tian, W.2
Takano, S.3
-
63
-
-
34250877865
-
Genetic pathways to primary and secondary glioblastoma
-
DOI 10.2353/ajpath.2007.070011
-
Ohgaki H, Kleihues P (2007) Genetic pathways to primary and secondary glioblastoma. Am J Pathol 170:1445-1453 (Pubitemid 47339290)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.5
, pp. 1445-1453
-
-
Ohgaki, H.1
Kleihues, P.2
-
64
-
-
55349107544
-
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
-
Jones DT, Kocialkowski S, Liu L et al (2008) Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res 68:8673-8677
-
(2008)
Cancer Res
, vol.68
, pp. 8673-8677
-
-
Jones, D.T.1
Kocialkowski, S.2
Liu, L.3
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