Alveolar macrophage depletion increases the severity of acute inflammation following nonlethal unilateral lung contusion in mice

Journal of Trauma and Acute Care Surgery

Volumn 76, Issue 4, 2014, Pages 982-990

  Machado Aranda, David ^a   V Suresh, Madathilparambil ^a   Yu, Bi ^a   Dolgachev, Vladislov ^a   Hemmila, Mark R ^a   Raghavendran, Krishnan ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

clodronate; lung contusion; lung injury; Macrophages; murine

Indexed keywords

ALBUMIN; CLODRONIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; CELL DEATH; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; HISTOPATHOLOGY; IMMUNE RESPONSE; INFLAMMATION; LEUKOCYTE COUNT; LUNG ALVEOLUS MACROPHAGE; LUNG COMPLIANCE; LUNG CONTUSION; LUNG INJURY; LUNG LAVAGE; LYMPHOCYTE DEPLETION; MALE; MEMBRANE PERMEABILITY; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL;

ACUTE DISEASE; ANIMALS; APOPTOSIS; BRONCHOALVEOLAR LAVAGE FLUID; CONTUSIONS; DISEASE MODELS, ANIMAL; IMMUNITY, CELLULAR; INFLAMMATION; LUNG INJURY; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; THORACIC INJURIES; WOUNDS, NONPENETRATING;

EID: 84897069139     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000000163     Document Type: Conference Paper

References (37)

1. Miller PR, Croce MA, Kilgo PD, Scott J, Fabian TC. Acute respiratory distress syndrome in blunt trauma: Identification of independent risk factors. Am Surg. 2002;68:845-850; discussion 850-851.
2. Cohn SM. Pulmonary contusion: Review of the clinical entity. J Trauma. 1997;42:973-979.
3. Kollmorgen DR, Murray KA, Sullivan JJ, Mone MC, Barton RG. Predictors ofmortality in pulmonary contusion. Am J Surg. 1994;168:659-663; discussion 663-664.
4. Bem RA, Farnand AW, Wong V, Koski A, Rosenfeld ME, Van Rooijen N, Frevert CW, Martin TR, Matute-Bello G. Depletion of resident alveolar macrophages does not prevent Fas-mediated lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2008;295:L314-L325.
5. Thepen T, Van Rooijen N, Kraal G. Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice. J Exp Med. 1989;170(2):499-509.
6. Young LR, Borchers MT, Allen HL, Gibbons RS, McCormack FX. Lung-restricted macrophage activation in the pearl mouse model of Hermansky-Pudlak syndrome. J Immunol. 2006;176:4361-4368.
7. Belperio JA, Keane MP, Burdick MD, Lynch JP 3rd, Xue YY, Berlin A, Ross DJ, Kunkel SL, Charo IF, Strieter RM. Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome. J Clin Invest. 2001;108:547-556.
8. Hogaboam CM, Gallinat CS, Bone-Larson C, Chensue SW, Lukacs NW, Strieter RM, Kunkel SL. Collagen deposition in a non-fibrotic lung granuloma model after nitric oxide inhibition. Am J Pathol. 1998;153: 1861-1872.
9. Broug-Holub E, Toews GB, Van Iwaarden JF, Strieter RM, Kunkel SL, Paine R 3rd, Standiford TJ. Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: Elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival. Infect Immun. 1997;65:1139-1146.
10. Suresh MV, Yu B, Machado-Aranda D, Bender MD, Ochoa-Frongia L, Helinski JD, Davidson BA, Knight PR, Hogaboam CM, Moore BB, Raghavendran K. Role of macrophage chemoattractant protein-1 in acute inflammation after lung contusion. Am J Respir Cell Mol Biol. 2012; 46(6):797-806.
11. Hoth JJ, Hudson WP, Brownlee NA, Yoza BK, Hiltbold EM, Meredith JW, McCall CE. Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion. Shock. 2007;28: 447-452.
12. Machado-Aranda D,Wang Z, Yu B, SureshMV, Notter RH, Raghavendran K. Increased phospholipase A2 and lyso-phosphatidylcholine levels are associated with surfactant dysfunction in lung contusion injury in mice. Surgery. 2013;153:25-35.
13. Machado-Aranda DA, SureshMV, Yu B, Raghavendran K. Electroporationmediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusion. J Trauma Acute Care Surg. 2012;72:32-39; discussion 39-40.
14. Vanoirbeek JA, Rinaldi M, De Vooght V, Haenen S, Bobic S, Gayan-Ramirez G, Hoet PH, Verbeken E, Decramer M, Nemery B, Janssens W. Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases. Am J Respir Cell Mol Biol. 2010;42:96-104.
15. Berg JT, Lee ST, Thepen T, Lee CY, Tsan MF. Depletion of alveolar macrophages by liposome-encapsulated dichloromethylene diphosphonate. J Appl Physiol. 1993;74:2812-2819.
16. Farley KS, Wang LF, Razavi HM, Law C, Rohan M, McCormack DG, Mehta S. Effects of macrophage inducible nitric oxide synthase in murine septic lung injury. Am J Physiol Lung Cell Mol Physiol. 2006;290: L1164-L1172.
17. Daly M, Miller PR, Carr JJ, Gayzik FS, Hoth JJ, Meredith JW, Stitzel JD. Traumatic pulmonary pathology measured with computed tomography and a semiautomated analytic method. Clin Imaging. 2008;32:346-354.
18. Miller PR, Croce MA, Bee TK, Qaisi WG, Smith CP, Collins GL, Fabian TC. ARDS after pulmonary contusion: Accurate measurement of contusion volume identifies high-risk patients. J Trauma. 2001;51:223-228; discussion 229-230.
19. Becher RD, Colonna AL, Enniss TM, Weaver AA, Crane DK, Martin RS, Mowery NT, Miller PR, Stitzel JD, Hoth JJ. An innovative approach to predict the development of adult respiratory distress syndrome in patients with blunt trauma. J Trauma Acute Care Surg. 2012;73(5):1229-1235.
20. Elder A, Johnston C, Gelein R, Finkelstein J, Wang Z, Notter R, Oberdorster G. Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate. Exp Lung Res. 2005;31:527-546.
21. Hashimoto S, Pittet JF, Hong K, Folkesson H, Bagby G, Kobzik L, Frevert C, Watanabe K, Tsurufuji S, Wiener-Kronish J. Depletion of alveolar macrophages decreases neutrophil chemotaxis to Pseudomonas airspace infections. Am J Physiol. 1996;270:L819-L828.
22. Van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications. J Immunol Methods. 1994;174(1-2):83-93.
23. OConnor JV, Kufera JA, Kerns TJ, Stein DM, Ho S, Dischinger PC, Scalea TM. Crash and occupant predictors of pulmonary contusion. J Trauma. 2009;66:1091-1095.
24. Gayzik FS, Martin RS, Gabler HC, Hoth JJ, Duma SM, Meredith JW, Stitzel JD. Characterization of crash-induced thoracic loading resulting in pulmonary contusion. J Trauma. 2009;66:840-849.
25. Raghavendran K, Davidson BA, Huebschmann JC, Helinski JD, Hutson AD, Dayton MT, Notter RH, Knight PR. Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. J Surg Res. 2009;155:273-282.
26. Raghavendran K, Davidson BA, Knight PR, Wang Z, Helinski J, Chess PR, Notter RH. Surfactant dysfunction in lung contusion with and without superimposed gastric aspiration in a rat model. Shock. 2008;30: 508-517.
27. Dolgachev VA, Yu B, Reinke JM, Raghavendran K, Hemmila MR. Host susceptibility to gram-negative pneumonia after lung contusion. J Trauma Acute Care Surg. 2012;72:614-622; discussion 622-623.
28. Clemedson CJ, Hultman H, Gronberg B. Respiration and pulmonary gas exchange in blast injury. J Appl Physiol. 1953;6:213-220.
29. Clemedson CJ, Pettersson H. Genesis of respiratory and circulatory changes in blast injury. Am J Physiol. 1953;174:316-320.
30. Raghavendran K, Davidson BA, Woytash JA, Helinski JD, Marschke CJ, Manderscheid PA, Notter RH, Knight PR. The evolution of isolated bilateral lung contusion from blunt chest trauma in rats: Cellular and cytokine responses. Shock. 2005;24:132-138.
31. Raghavendran K, Davidson BA, Mullan BA, Hutson AD, Russo TA, Manderscheid PA, Woytash JA, Holm BA, Notter RH, Knight PR. Acid and particulate-induced aspiration lung injury in mice: Importance of MCP-1. Am J Physiol Lung Cell Mol Physiol. 2005;289:L134-L143.
32. Raghavendran K, Nemzek J, Napolitano LM, Knight PR. Aspiration-induced lung injury. Crit Care Med. 2011;39:818-826.
33. Raghavendran K, Notter RH, Davidson BA, Helinski JD, Kunkel SL, Knight PR. Lung contusion: Inflammatory mechanisms and interaction with other injuries. Shock. 2009;32:122-130.
34. MacDonald KP, Palmer JS, Cronau S, Seppanen E, Olver S, Raffelt NC, Kuns R, Pettit AR, Clouston A, Wainwright B. An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue-and tumor-associated macrophages but does not inhibit inflammation. Blood. 2010;116:3955-3963.
35. Pradilla G, Wang PP, Legnani FG, Ogata L, Dietsch GN, Tamargo RJ. Prevention of vasospasm by anti-CD11/CD18 monoclonal antibody therapy following subarachnoid hemorrhage in rabbits. J Neurosurg. 2004; 101(1):88-92.
36. Yeo LY, Friend JR, McIntosh MP, Meeusen EN, Morton DA. Ultrasonic nebulization platforms for pulmonary drug delivery. Expert Opin Drug Deliv. 2010;7(6):663-679.
37. Driscoll KE, Costa DL, Hatch G, Henderson R, Oberdorster G, Salem H, Schlesinger RB. Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: Uses and limitations. Toxicol Sci. 2000;55(1):24-35.