Increased and Imbalanced dNTP Pools Symmetrically Promote Both Leading and Lagging Strand Replication Infidelity

PLoS Genetics

Volumn 10, Issue 12, 2014, Pages

  Buckland, Robert J ^a   Watt, Danielle L ^b   Chittoor, Balasubramanyam ^a   Nilsson, Anna Karin ^a   Kunkel, Thomas A ^b   Chabes, Andrei ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYCYTIDINE TRIPHOSPHATE; DEOXYRIBONUCLEOSIDE TRIPHOSPHATE; RIBONUCLEOTIDE REDUCTASE; 2'-DEOXYADENOSINE TRIPHOSPHATE; 2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE; DEOXYADENOSINE PHOSPHATE; DEOXYCYTIDINE PHOSPHATE; DEOXYGUANOSINE PHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; PYRIMIDINE NUCLEOTIDE; THYMIDINE 5'-TRIPHOSPHATE;

ARTICLE; BASE MISPAIRING; CAN1 GENE; DNA REPLICATION; DNA STRAND; FUNGAL GENOME; FUNGAL STRAIN; FUNGUS MUTATION; MISMATCH REPAIR; MUTATION RATE; NONHUMAN; REPORTER GENE; SPONTANEOUS MUTATION; GENETICS; GENOMIC INSTABILITY; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE; TRANSGENIC ORGANISM;

BASE PAIR MISMATCH; BASE SEQUENCE; DEOXYADENINE NUCLEOTIDES; DEOXYCYTOSINE NUCLEOTIDES; DEOXYGUANINE NUCLEOTIDES; DNA MISMATCH REPAIR; DNA REPLICATION; GENOMIC INSTABILITY; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION RATE; ORGANISMS, GENETICALLY MODIFIED; SACCHAROMYCES CEREVISIAE; THYMINE NUCLEOTIDES;

EID: 84919684017     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004846     Document Type: Article

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