Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression

Cell Metabolism

Volumn 20, Issue 6, 2014, Pages 979-990

  Brouwers, Bas ^a   De Faudeur, Geoffroy ^a   Osipovich, Anna B ^b   Goyvaerts, Lotte ^a   Lemaire, Katleen ^a   Boesmans, Leen ^a   Cauwelier, Elisa J G ^a   Granvik, Mikaela ^a   Pruniau, Vincent P E G ^a   Van Lommel, Leentje ^a   Van Schoors, Jolien ^c   Stancill, Jennifer S ^b   Smolders, Ilse ^c   Goffin, Vincent ^d   Binart, Nadine ^d   In'T Veld, Peter ^e   Declercq, Jeroen ^a   Magnuson, Mark A ^b   Creemers, John W M ^a   Schuit, Frans ^a   Schraenen, Anica ^a   more..

^a UNIVERSITY OF LEUVEN   (Belgium)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^d INSERM   (France)

^e DIABETES RESEARCH CENTER   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 2; HUMAN GROWTH HORMONE; INSULIN; PROLACTIN RECEPTOR; SEROTONIN; TPH1 PROTEIN, MOUSE; TRYPTOPHAN HYDROXYLASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HORMONE RECEPTOR INTERACTION; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; ANIMAL; GENETICS; HUMAN; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

ANIMALS; FEMALE; HUMAN GROWTH HORMONE; HUMANS; ISLETS OF LANGERHANS; MALE; MICE; MICE, TRANSGENIC; RECEPTORS, PROLACTIN; TRYPTOPHAN HYDROXYLASE;

EID: 84919645042     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.11.004     Document Type: Article

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