Ligand Binding and functional selectivity of L-tryptophan metabolites at the mouse aryl hydrocarbon receptor (mAhR)

Journal of Chemical Information and Modeling

Volumn 54, Issue 12, 2014, Pages 3373-3383

  Nuti, Roberto ^a   Gargaro, Marco ^a   Matino, Davide ^a   Dolciami, Daniela ^a   Grohmann, Ursula ^a   Puccetti, Paolo ^a   Fallarino, Francesca ^a   Macchiarulo, Antonio ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOMOLECULES; DISEASES; HYDROCARBONS; LIME; MOLECULAR DYNAMICS; TRANSCRIPTION;

2 ,3 ,7 ,8 TETRACHLORODIBENZO P DIOXINS; ARYL HYDROCARBON RECEPTOR; DESIGN AND DEVELOPMENT; HYPERINFLAMMATORY RESPONSE; INFECTIOUS DISEASE; MUTAGENESIS EXPERIMENT; TOXICOLOGICAL EFFECTS; TRYPTOPHAN CATABOLISM;

METABOLITES;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 6-FORMYLINDOLO(3,2-B)CARBAZOLE; AHR PROTEIN, MOUSE; AROMATIC HYDROCARBON RECEPTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CARBAZOLE DERIVATIVE; KYNURENINE; LIGAND; PROTEIN BINDING; TRANSCRIPTOME; TRYPTOPHAN;

ANIMAL; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOUSE; MUTAGENESIS; PROTEIN TERTIARY STRUCTURE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARBAZOLES; KYNURENINE; LIGANDS; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ARYL HYDROCARBON; SUBSTRATE SPECIFICITY; TETRACHLORODIBENZODIOXIN; TRANSCRIPTOME; TRYPTOPHAN;

EID: 84919628754     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci5005459     Document Type: Article

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