New aryl hydrocarbon receptor homology model targeted to improve docking reliability

Journal of Chemical Information and Modeling

Volumn 51, Issue 11, 2011, Pages 2868-2881

  Motto, Ilaria ^a   Bordogna, Annalisa ^a   Soshilov, Anatoly A ^b   Denison, Michael S ^b   Bonati, Laura ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; HYDROCARBONS; TRANSCRIPTION;

2 ,3 ,7 ,8 TETRACHLORODIBENZO P DIOXINS; ARYL HYDROCARBON RECEPTOR; BASIC HELIX LOOP HELIXES; ENVIRONMENTAL CONTAMINANT; FUNCTIONAL ACTIVITIES; HYPOXIA-INDUCIBLE FACTORS; LIGAND BINDING DOMAIN; TEMPLATE STRUCTURES;

LIGANDS;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HELIX LOOP HELIX PROTEIN; LIGAND; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BINDING COMPETITION; BINDING SITE; BIOLOGY; CELL STRAIN COS1; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG POTENTIATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MUTATION; PLASMID; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; BINDING, COMPETITIVE; CERCOPITHECUS AETHIOPS; COMPUTATIONAL BIOLOGY; COS CELLS; CRYSTALLOGRAPHY, X-RAY; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION; HELIX-LOOP-HELIX MOTIFS; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PLASMIDS; PROTEIN BINDING; RECEPTORS, ARYL HYDROCARBON; RECOMBINANT PROTEINS; TETRACHLORODIBENZODIOXIN; TRANSFECTION;

EID: 82355168493     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci2001617     Document Type: Article

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