Mangiferin treatment inhibits hepatic expression of acyl-coenzyme A: Diacylglycerol acyltransferase-2 in fructose-fed spontaneously hypertensive rats: A link to amelioration of fatty liver

Toxicology and Applied Pharmacology

Volumn 280, Issue 2, 2014, Pages 207-215

  Xing, Xiaomang ^a   Li, Danyang ^a   Chen, Dilong ^a   Zhou, Liang ^a   Chonan, Ritsu ^b   Yamahara, Johji ^c   Wang, Jianwei ^a   Li, Yuhao ^d  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

^c Pharmafood Institute   (Japan)

^d NSW Office of Environment and Heritage NSW   (Australia)

Author keywords

DGAT 2; Fructose; Liver; Mangiferin; SHR; Steatosis

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; ACYL COENZYME A OXIDASE; ACYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE I; CHOLESTEROL; COLLAGEN TYPE 1; DIACYLGLYCEROL ACYLTRANSFERASE 1; DIACYLGLYCEROL ACYLTRANSFERASE 2; FATTY ACID; FATTY ACID SYNTHASE; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MANGIFERIN; MESSENGER RNA; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; MONOACYGLYCEROL ACYLTRANSFERASE 2; MONOCYTE CHEMOTACTIC PROTEIN 1; NUCLEAR PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PYRUVATE KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DGAT1 PROTEIN, RAT; DGAT2 PROTEIN, RAT; DIACYLGLYCEROL ACYLTRANSFERASE; FRUCTOSE; XANTHONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; FATTY ACID SYNTHESIS; FATTY LIVER; GENE EXPRESSION; GENE MUTATION; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; LIPID METABOLISM; LIVER WEIGHT; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WHITE ADIPOSE TISSUE; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; GENETICS; LIVER; SPONTANEOUSLY HYPERTENSIVE RAT;

RATTUS;

ANIMALS; DIACYLGLYCEROL O-ACYLTRANSFERASE; FATTY LIVER; FRUCTOSE; LIVER; MALE; RATS; RATS, INBRED SHR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; XANTHONES;

EID: 84919399681     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.08.001     Document Type: Article

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