Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat

Hypertension

Volumn 51, Issue 1, 2008, Pages 148-153

  Pravenec, Michal ^a,d   Kazdova, Ludmila ^b   Landa, Vladimir ^a   Zidek, Vaclav ^a   Mlejnek, Petr ^a   Simakova, Miroslava ^a   Jansa, Petr ^c   Forejt, Jiri ^c   Kren, Vladimir ^a,d   Krenova, Drahomira ^d   Qi, Nathan ^e   Wang, Jia Ming ^f   Chan, Derrick ^f   Aitman, Timothy J ^g   Kurtz, Theodore W ^f,h  

^a INSTITUTE OF MATHEMATICS   (Czech Republic)

^b INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^c INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^d CHARLES UNIVERSITY   (Czech Republic)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g IMPERIAL COLLEGE LONDON   (United Kingdom)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fatty liver; Hypertension; Inbred SHR; Metabolic syndrome X; Quantitative trait loci; Rats; Sterol regulatory element binding protein 1

Indexed keywords

ACYL COENZYME A DESATURASE; CHOLESTEROL; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BROWN NORWAY RAT; CHOLESTEROL DIET; CHOLESTEROL LIVER LEVEL; CHOLESTEROL SYNTHESIS; COMPARATIVE STUDY; CONTROLLED STUDY; FATTY LIVER; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFICIENCY; QUANTITATIVE TRAIT LOCUS; RAT; SPONTANEOUSLY HYPERTENSIVE HEART FAILURE RAT;

ALLELES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOOD PRESSURE; CHOLESTEROL; FATTY LIVER; FEMALE; HYPERTENSION; LIVER; MALE; MUTATION; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED BN; RATS, INBRED SHR; RISK FACTORS; SEQUENCE ANALYSIS, DNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 37349074067     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.100743     Document Type: Article

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