Aldehyde dehydrogenases in cancer: An opportunity for biomarker and drug development?

Drug Discovery Today

Volumn 19, Issue 12, 2014, Pages 1953-1963

  Pors, Klaus ^a   Moreb, Jan S ^b  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b Hematological Malignancies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE INHIBITOR; CHLORPROPAMIDE; CYTARABINE; DAIDZIN; DISULFIRAM; GOSSYPOL; ISOENZYME; PARGYLINE; TUMOR MARKER; TYROSINE; ANTINEOPLASTIC AGENT;

ACUTE GRANULOCYTIC LEUKEMIA; ADVANCED CANCER; APOPTOSIS; BREAST CANCER; CANCER GRADING; CANCER PROGNOSIS; CANCER RESEARCH; CANCER RESISTANCE; CANCER STEM CELL; CANCER SURVIVAL; CELL CYCLE ARREST; CELL PROLIFERATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CHROMOSOMAL LOCALIZATION; CLEAR CELL CARCINOMA; COLON CANCER; CYTOPLASM; DNA METHYLATION; ENZYME ACTIVITY; ESOPHAGUS CANCER; GALLBLADDER CANCER; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; INFLAMMATORY BREAST CANCER; LUNG CANCER; METASTASIS; MICROSOME; MITOCHONDRION; NEOPLASM; NUCLEOTIDE SEQUENCE; OVARY CANCER; OVERALL SURVIVAL; OXIDATIVE STRESS; PANCREAS CANCER; PROSTATE CANCER; PROTEIN EXPRESSION; RECTUM CANCER; REVIEW; SURVIVAL TIME; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG DEVELOPMENT; ENZYMOLOGY; METABOLISM; NEOPLASMS;

ALDEHYDE DEHYDROGENASE; ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DISCOVERY; HUMANS; ISOENZYMES; NEOPLASMS; NEOPLASTIC STEM CELLS; TUMOR MARKERS, BIOLOGICAL;

EID: 84919346697     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2014.09.009     Document Type: Review

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