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Volumn 9, Issue 11, 2014, Pages

Replication rates of mycobacterium tuberculosis in human macrophages do not correlate with mycobacterial antibiotic susceptibility

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCOBACTERIAL AGENT; ETHAMBUTOL; ISONIAZID; PYRAZINAMIDE; TUBERCULOSTATIC AGENT;

EID: 84919341505     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112426     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 79959927732 scopus 로고    scopus 로고
    • Tuberculosis
    • Lawn SD, Zumla AI (2011) Tuberculosis. Lancet 378: 57-72.
    • (2011) Lancet , vol.378 , pp. 57-72
    • Lawn, S.D.1    Zumla, A.I.2
  • 2
    • 84875552831 scopus 로고    scopus 로고
    • Shortening the 'short-course' therapyinsights into host immunity may contribute to new treatment strategies for tuberculosis
    • Schon T, Lerm M, Stendahl O (2013) Shortening the 'short-course' therapyinsights into host immunity may contribute to new treatment strategies for tuberculosis. J Intern Med 273: 368-382.
    • (2013) J Intern Med , vol.273 , pp. 368-382
    • Schon, T.1    Lerm, M.2    Stendahl, O.3
  • 3
    • 0029976980 scopus 로고    scopus 로고
    • An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence
    • Wayne LG, Hayes LG (1996) An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect Immun 64: 2062-2069.
    • (1996) Infect Immun , vol.64 , pp. 2062-2069
    • Wayne, L.G.1    Hayes, L.G.2
  • 4
    • 0005477742 scopus 로고
    • The uptake of isoniazid and related compounds by Mycobacteria
    • Youatt J (1960) The uptake of isoniazid and related compounds by Mycobacteria. Aust J Exp Biol Med Sci 38: 331-337.
    • (1960) Aust J Exp Biol Med Sci , vol.38 , pp. 331-337
    • Youatt, J.1
  • 5
    • 0030892547 scopus 로고    scopus 로고
    • The requirement for manganese and oxygen in the isoniazid-dependent inactivation of mycobacterium tuberculosis enoyl reductase
    • Zabinski RF, Blanchard JS (1997) The Requirement for Manganese and Oxygen in the Isoniazid-Dependent Inactivation of Mycobacterium tuberculosis Enoyl Reductase. J Am Chem Soc 119: 2331-2332.
    • (1997) J Am Chem Soc , vol.119 , pp. 2331-2332
    • Zabinski, R.F.1    Blanchard, J.S.2
  • 6
    • 0029912749 scopus 로고    scopus 로고
    • Evidence for isoniazid oxidation by oxyferrous mycobacterial catalase2peroxidase
    • Magliozzo RS, Marcinkeviciene JA (1996) Evidence for Isoniazid Oxidation by Oxyferrous Mycobacterial Catalase2Peroxidase. J Am Chem Soc 118.
    • (1996) J Am Chem Soc , pp. 118
    • Magliozzo, R.S.1    Marcinkeviciene, J.A.2
  • 7
    • 0034502343 scopus 로고    scopus 로고
    • Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection
    • Hernandez-Pando R, Jeyanathan M, Mengistu G, Aguilar D, Orozco H, et al. (2000) Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. Lancet 356: 2133-2138.
    • (2000) Lancet , vol.356 , pp. 2133-2138
    • Hernandez-Pando, R.1    Jeyanathan, M.2    Mengistu, G.3    Aguilar, D.4    Orozco, H.5
  • 9
    • 84960961533 scopus 로고
    • The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug
    • McCune RM Jr, McDermott W, Tompsett R (1956) The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug. J Exp Med 104: 763-802.
    • (1956) J Exp Med , vol.104 , pp. 763-802
    • McCune, R.M.1    McDermott, W.2    Tompsett, R.3
  • 10
    • 46249108568 scopus 로고    scopus 로고
    • Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates
    • Via LE, Lin PL, Ray SM, Carrillo J, Allen SS, et al. (2008) Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates. Infect Immun 76: 2333-2340.
    • (2008) Infect Immun , vol.76 , pp. 2333-2340
    • Via, L.E.1    Lin, P.L.2    Ray, S.M.3    Carrillo, J.4    Allen, S.S.5
  • 11
    • 33750503812 scopus 로고    scopus 로고
    • Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice
    • Aly S, Wagner K, Keller C, Malm S, Malzan A, et al. (2006) Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. J Pathol 210: 298-305.
    • (2006) J Pathol , vol.210 , pp. 298-305
    • Aly, S.1    Wagner, K.2    Keller, C.3    Malm, S.4    Malzan, A.5
  • 12
    • 33644832153 scopus 로고    scopus 로고
    • Characterization of the tuberculous granuloma in murine and human lungs: Cellular composition and relative tissue oxygen tension
    • Tsai MC, Chakravarty S, Zhu G, Xu J, Tanaka K, et al. (2006) Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension. Cell Microbiol 8: 218-232.
    • (2006) Cell Microbiol , vol.8 , pp. 218-232
    • Tsai, M.C.1    Chakravarty, S.2    Zhu, G.3    Xu, J.4    Tanaka, K.5
  • 14
    • 79959815079 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages
    • Daniel J, Maamar H, Deb C, Sirakova TD, Kolattukudy PE (2011) Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages. PLoS Pathog 7: e1002093.
    • (2011) PLoS Pathog , vol.7 , pp. e1002093
    • Daniel, J.1    Maamar, H.2    Deb, C.3    Sirakova, T.D.4    Kolattukudy, P.E.5
  • 15
    • 84867244793 scopus 로고    scopus 로고
    • A novel in vitro human macrophage model to study the persistence of mycobacterium tuberculosis using vitamin d(3) and retinoic acid activated thp-1 macrophages
    • Estrella JL, Kan-Sutton C, Gong X, Rajagopalan M, Lewis DE, et al. (2011) A Novel in vitro Human Macrophage Model to Study the Persistence of Mycobacterium tuberculosis Using Vitamin D(3) and Retinoic Acid Activated THP-1 Macrophages. Front Microbiol 2: 67.
    • (2011) Front Microbiol , vol.2 , pp. 67
    • Estrella, J.L.1    Kan-Sutton, C.2    Gong, X.3    Rajagopalan, M.4    Lewis, D.E.5
  • 16
    • 80053413551 scopus 로고    scopus 로고
    • In vitro differentiation of human macrophages with enhanced antimycobacterial activity
    • Vogt G, Nathan C (2011) In vitro differentiation of human macrophages with enhanced antimycobacterial activity. J Clin Invest 121: 3889-3901.
    • (2011) J Clin Invest , vol.121 , pp. 3889-3901
    • Vogt, G.1    Nathan, C.2
  • 17
    • 67650655950 scopus 로고    scopus 로고
    • A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen
    • Deb C, Lee CM, Dubey VS, Daniel J, Abomoelak B, et al. (2009) A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen. PLoS One 4: e6077.
    • (2009) PLoS One , vol.4 , pp. e6077
    • Deb, C.1    Lee, C.M.2    Dubey, V.S.3    Daniel, J.4    Abomoelak, B.5
  • 18
    • 80052050200 scopus 로고    scopus 로고
    • Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages
    • Welin A, Raffetseder J, Eklund D, Stendahl O, Lerm M (2011) Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages J Innate Immun 3: 508-518.
    • (2011) J Innate Immun , vol.3 , pp. 508-518
    • Welin, A.1    Raffetseder, J.2    Eklund, D.3    Stendahl, O.4    Lerm, M.5
  • 19
    • 84864044868 scopus 로고    scopus 로고
    • Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection
    • Rohde KH, Veiga DF, Caldwell S, Balazsi G, Russell DG (2012) Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection. PLoS Pathog 8: e1002769.
    • (2012) PLoS Pathog , vol.8 , pp. e1002769
    • Rohde, K.H.1    Veiga, D.F.2    Caldwell, S.3    Balazsi, G.4    Russell, D.G.5
  • 20
    • 11144339323 scopus 로고    scopus 로고
    • Replication dynamics of Mycobacterium tuberculosis in chronically infected mice
    • Muñoz-Elías E, Timm J, Botha T, Chan W-T, Gomez J, et al. (2005) Replication dynamics of Mycobacterium tuberculosis in chronically infected mice. Infect Immun 73: 546-551.
    • (2005) Infect Immun , vol.73 , pp. 546-551
    • Muñoz-Elías, E.1    Timm, J.2    Botha, T.3    Chan, W.-T.4    Gomez, J.5
  • 21
    • 84891853921 scopus 로고    scopus 로고
    • Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
    • Lin P, Ford C, Coleman M, Myers A, Gawande R, et al. (2014) Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nature Med 20: 75-79.
    • (2014) Nature Med , vol.20 , pp. 75-79
    • Lin, P.1    Ford, C.2    Coleman, M.3    Myers, A.4    Gawande, R.5
  • 24
    • 84884254559 scopus 로고    scopus 로고
    • Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria
    • Santi I, Dhar N, Bousbaine D, Wakamoto Y, McKinney JD (2013) Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria. Nat Commun 4: 2470.
    • (2013) Nat Commun , vol.4 , pp. 2470
    • Santi, I.1    Dhar, N.2    Bousbaine, D.3    Wakamoto, Y.4    McKinney, J.D.5
  • 25
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8: 958-969.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 26
    • 0032767290 scopus 로고    scopus 로고
    • Assessment of immunity to mycobacterial infection with luciferase reporter constructs
    • Snewin VA, Gares MP, Gaora PO, Hasan Z, Brown IN, et al. (1999) Assessment of immunity to mycobacterial infection with luciferase reporter constructs. Infect Immun 67: 4586-4593.
    • (1999) Infect Immun , vol.67 , pp. 4586-4593
    • Snewin, V.A.1    Gares, M.P.2    Gaora, P.O.3    Hasan, Z.4    Brown, I.N.5
  • 27
    • 0242552007 scopus 로고    scopus 로고
    • Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection
    • Seiler P, Ulrichs T, Bandermann S, Pradl L, Jorg S, et al. (2003) Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection. J Infect Dis 188: 1326-1331.
    • (2003) J Infect Dis , vol.188 , pp. 1326-1331
    • Seiler, P.1    Ulrichs, T.2    Bandermann, S.3    Pradl, L.4    Jorg, S.5
  • 28
    • 43249101747 scopus 로고    scopus 로고
    • Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum
    • Garton NJ, Waddell SJ, Sherratt AL, Lee SM, Smith RJ, et al. (2008) Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum. PLoS Med 5: e75.
    • (2008) PLoS Med , vol.5 , pp. e75
    • Garton, N.J.1    Waddell, S.J.2    Sherratt, A.L.3    Lee, S.M.4    Smith, R.J.5
  • 29
    • 0032936728 scopus 로고    scopus 로고
    • Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide
    • Zhang Y, Scorpio A, Nikaido H, Sun Z (1999) Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide. J Bacteriol 181: 2044-2049.
    • (1999) J Bacteriol , vol.181 , pp. 2044-2049
    • Zhang, Y.1    Scorpio, A.2    Nikaido, H.3    Sun, Z.4
  • 30
    • 79953279193 scopus 로고    scopus 로고
    • Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
    • Adams KN, Takaki K, Connolly LE, Wiedenhoft H, Winglee K, et al. (2011) Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145: 39-53.
    • (2011) Cell , vol.145 , pp. 39-53
    • Adams, K.N.1    Takaki, K.2    Connolly, L.E.3    Wiedenhoft, H.4    Winglee, K.5
  • 31
    • 57149096869 scopus 로고    scopus 로고
    • Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. Tuberculosis persistence
    • Peyron P, Vaubourgeix J, Poquet Y, Levillain F, Botanch C, et al. (2008) Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence. PLoS Pathog 4: e1000204.
    • (2008) PLoS Pathog , vol.4 , pp. e1000204
    • Peyron, P.1    Vaubourgeix, J.2    Poquet, Y.3    Levillain, F.4    Botanch, C.5
  • 32
    • 61649103963 scopus 로고    scopus 로고
    • Evolution of foamy macrophages in the pulmonary granulomas of experimental tuberculosis models
    • Caceres N, Tapia G, Ojanguren I, Altare F, Gil O, et al. (2009) Evolution of foamy macrophages in the pulmonary granulomas of experimental tuberculosis models. Tuberculosis (Edinb) 89: 175-182.
    • (2009) Tuberculosis (Edinb , vol.89 , pp. 175-182
    • Caceres, N.1    Tapia, G.2    Ojanguren, I.3    Altare, F.4    Gil, O.5
  • 33
    • 79957554114 scopus 로고    scopus 로고
    • Human macrophages infected with a high burden of esat-6-expressing m tuberculosis undergo caspase-1-and cathepsin b-independent necrosis
    • Welin A, Eklund D, Stendahl O, Lerm M (2011) Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1-and Cathepsin B-Independent Necrosis. PLoS One 6: e20302.
    • (2011) PLoS One , vol.6 , pp. e20302
    • Welin, A.1    Eklund, D.2    Stendahl, O.3    Lerm, M.4
  • 34
    • 34247572374 scopus 로고    scopus 로고
    • Deletion of kasb in mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice
    • Bhatt A, Fujiwara N, Bhatt K, Gurcha SS, Kremer L, et al. (2007) Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice. Proc Natl Acad Sci U S A 104: 5157-5162.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5157-5162
    • Bhatt, A.1    Fujiwara, N.2    Bhatt, K.3    Gurcha, S.S.4    Kremer, L.5
  • 35
    • 38849177346 scopus 로고    scopus 로고
    • Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages
    • Tailleux L, Waddell SJ, Pelizzola M, Mortellaro A, Withers M, et al. (2008) Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages. PLoS One 3: e1403.
    • (2008) PLoS One , vol.3 , pp. e1403
    • Tailleux, L.1    Waddell, S.J.2    Pelizzola, M.3    Mortellaro, A.4    Withers, M.5
  • 37
    • 84892181925 scopus 로고    scopus 로고
    • Internalization of Salmonella by macrophages induces formation of nonreplicating persisters
    • Helaine S, Cheverton A, Watson K, Faure L, Matthews S, et al. (2014) Internalization of Salmonella by macrophages induces formation of nonreplicating persisters. Science 343: 204-208.
    • (2014) Science , vol.343 , pp. 204-208
    • Helaine, S.1    Cheverton, A.2    Watson, K.3    Faure, L.4    Matthews, S.5
  • 38
    • 78650211749 scopus 로고    scopus 로고
    • Viewpoint: Scientific dogmas, paradoxes and mysteries of latent mycobacterium tuberculosis infection
    • Zumla A, Atun R, Maeurer M, Mwaba P, Ma Z, et al. (2011) Viewpoint: Scientific dogmas, paradoxes and mysteries of latent Mycobacterium tuberculosis infection. Trop Med Int Health TM & IH 16: 79-83.
    • (2011) Trop Med Int Health TM & IH , vol.16 , pp. 79-83
    • Zumla, A.1    Atun, R.2    Maeurer, M.3    Mwaba, P.4    Ma, Z.5
  • 39
    • 0024338472 scopus 로고
    • Activity and penetration of antituberculosis drugs in mouse peritoneal macrophages infected with Mycobacterium microti OV254
    • Dhillon J, Mitchison DA (1989) Activity and penetration of antituberculosis drugs in mouse peritoneal macrophages infected with Mycobacterium microti OV254. Antimicrob Agents Chemother 33: 1255-1259.
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 1255-1259
    • Dhillon, J.1    Mitchison, D.A.2
  • 40
    • 0029761216 scopus 로고    scopus 로고
    • In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages
    • Rastogi N, Labrousse V, Goh KS (1996) In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. Curr Microbiol 33: 167-175.
    • (1996) Curr Microbiol , vol.33 , pp. 167-175
    • Rastogi, N.1    Labrousse, V.2    Goh, K.S.3
  • 41
    • 77950686614 scopus 로고    scopus 로고
    • Validation of a medium-throughput method for evaluation of intracellular growth of Mycobacterium tuberculosis
    • Eklund D, Welin A, Schon T, Stendahl O, Huygen K, et al. (2010) Validation of a medium-throughput method for evaluation of intracellular growth of Mycobacterium tuberculosis. Clin Vaccine Immunol 17: 513-517.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 513-517
    • Eklund, D.1    Welin, A.2    Schon, T.3    Stendahl, O.4    Huygen, K.5


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