Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide

Journal of Bacteriology

Volumn 181, Issue 7, 1999, Pages 2044-2049

  Zhang, Ying ^a   Scorpio, Angelo ^a,c   Nikaido, Hiroshi ^b   Sun, Zhonghe ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Virus Research Institute Inc Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLIZING ENZYME; PYRAZINAMIDE; PYRAZINOIC ACID; RESERPINE; VALINOMYCIN;

ACIDITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG MECHANISM; DRUG METABOLISM; DRUG TRANSPORT; ENZYME LOCALIZATION; ESCHERICHIA COLI; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PH; PRIORITY JOURNAL; REACTION ANALYSIS; SPECIES DIFFERENCE;

ACTINOBACTERIA (CLASS); CORYNEBACTERINEAE; ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; POA; UNCULTURED ACTINOMYCETE;

EID: 0032936728     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.7.2044-2049.1999     Document Type: Article

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