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Volumn 34, Issue 24, 2014, Pages 4389-4403

ALK5 and ALK1 play antagonistic roles in transforming growth factor β-induced podosome formation in aortic endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; BONE MORPHOGENETIC PROTEIN 9; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; ACTIVIN RECEPTOR; PROTEIN SERINE THREONINE KINASE; RECEPTOR REGULATED SMAD PROTEIN; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 84918835995     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01026-14     Document Type: Article
Times cited : (27)

References (56)
  • 1
    • 80054031825 scopus 로고    scopus 로고
    • Degrading devices: invadosomes in proteolytic cell invasion
    • Linder S, Wiesner C, Himmel M. 2011. Degrading devices: invadosomes in proteolytic cell invasion. Annu. Rev. Cell Dev. Biol. 27:185-211. http://dx.doi.org/10.1146/annurev-cellbio-092910-154216.
    • (2011) Annu. Rev. Cell Dev. Biol. , vol.27 , pp. 185-211
    • Linder, S.1    Wiesner, C.2    Himmel, M.3
  • 3
    • 70849107646 scopus 로고    scopus 로고
    • TGFbeta-induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels
    • Rottiers P, Saltel F, Daubon T, Chaigne-Delalande B, Tridon V, Billottet C, Reuzeau E, Genot E. 2009. TGFbeta-induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels. J. Cell Sci. 122:4311-4318. http://dx.doi.org/10.1242/jcs.057448.
    • (2009) J. Cell Sci. , vol.122 , pp. 4311-4318
    • Rottiers, P.1    Saltel, F.2    Daubon, T.3    Chaigne-Delalande, B.4    Tridon, V.5    Billottet, C.6    Reuzeau, E.7    Genot, E.8
  • 4
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE. 2003. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425:577-584. http://dx.doi.org/10.1038/nature02006.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 5
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGF-beta-Smad signalling
    • ten Dijke P, Hill CS. 2004. New insights into TGF-beta-Smad signalling. Trends Biochem. Sci. 29:265-273. http://dx.doi.org/10.1016/j.tibs.2004.03.008.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 265-273
    • ten Dijke, P.1    Hill, C.S.2
  • 6
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-beta signals
    • Moustakas A, Heldin CH. 2005. Non-Smad TGF-beta signals. J. Cell Sci. 118:3573-3584. http://dx.doi.org/10.1242/jcs.02554.
    • (2005) J. Cell Sci. , vol.118 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2
  • 7
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J. 2003. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113:685-700. http://dx.doi.org/10.1016/S0092-8674(03)00432-X.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 9
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
    • Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, ten Dijke P. 2002. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J. 21:1743-1753. http://dx.doi.org/10.1093/emboj/21.7.1743.
    • (2002) EMBO J. , vol.21 , pp. 1743-1753
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5    ten Dijke, P.6
  • 11
    • 21644452716 scopus 로고    scopus 로고
    • Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factorbeta receptor complex
    • Blanco FJ, Santibanez JF, Guerrero-Esteo M, Langa C, Vary CP, Bernabeu C. 2005. Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factorbeta receptor complex. J. Cell. Physiol. 204:574-584. http://dx.doi.org/10.1002/jcp.20311.
    • (2005) J. Cell. Physiol. , vol.204 , pp. 574-584
    • Blanco, F.J.1    Santibanez, J.F.2    Guerrero-Esteo, M.3    Langa, C.4    Vary, C.P.5    Bernabeu, C.6
  • 14
    • 33847369980 scopus 로고    scopus 로고
    • Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
    • David L, Mallet C, Mazerbourg S, Feige JJ, Bailly S. 2007. Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 109:1953-1961. http://dx.doi.org/10.1182/blood-2006-07-034124.
    • (2007) Blood , vol.109 , pp. 1953-1961
    • David, L.1    Mallet, C.2    Mazerbourg, S.3    Feige, J.J.4    Bailly, S.5
  • 15
  • 17
    • 0023634584 scopus 로고
    • Clinical spectrum of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease)
    • Peery WH. 1987. Clinical spectrum of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease). Am. J. Med. 82:989-997. http://dx.doi.org/10.1016/0002-9343(87)90162-8.
    • (1987) Am. J. Med. , vol.82 , pp. 989-997
    • Peery, W.H.1
  • 18
    • 84871818852 scopus 로고    scopus 로고
    • Retention in the endoplasmic reticulum is the underlying mechanism of some hereditary haemorrhagic telangiectasia type 2 ALK1 missense mutations
    • Hume AN, John A, Akawi NA, Al-Awadhi AM, Al-Suwaidi SS, Al-Gazali L, Ali BR. 2013. Retention in the endoplasmic reticulum is the underlying mechanism of some hereditary haemorrhagic telangiectasia type 2 ALK1 missense mutations. Mol. Cell. Biochem. 373:247-257. http://dx.doi.org/10.1007/s11010-012-1496-3.
    • (2013) Mol. Cell. Biochem. , vol.373 , pp. 247-257
    • Hume, A.N.1    John, A.2    Akawi, N.A.3    Al-Awadhi, A.M.4    Al-Suwaidi, S.S.5    Al-Gazali, L.6    Ali, B.R.7
  • 20
    • 38349173601 scopus 로고    scopus 로고
    • ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2
    • Park SO, Lee YJ, Seki T, Hong KH, Fliess N, Jiang Z, Park A, Wu X, Kaartinen V, Roman BL, Oh SP. 2008. ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2. Blood 111:633-642. http://dx.doi.org/10.1182/blood-2007-08-107359.
    • (2008) Blood , vol.111 , pp. 633-642
    • Park, S.O.1    Lee, Y.J.2    Seki, T.3    Hong, K.H.4    Fliess, N.5    Jiang, Z.6    Park, A.7    Wu, X.8    Kaartinen, V.9    Roman, B.L.10    Oh, S.P.11
  • 22
    • 0033757655 scopus 로고    scopus 로고
    • Arteriovenous malformations in mice lacking activin receptor-like kinase-1
    • Urness LD, Sorensen LK, Li DY. 2000. Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat. Genet. 26:328-331. http://dx.doi.org/10.1038/81634.
    • (2000) Nat. Genet. , vol.26 , pp. 328-331
    • Urness, L.D.1    Sorensen, L.K.2    Li, D.Y.3
  • 23
    • 26444609583 scopus 로고    scopus 로고
    • Blood outgrowth endothelial cells from hereditary haemorrhagic telangiectasia patients reveal abnormalities compatible with vascular lesions
    • Fernandez-Lopez A, Sanz-Rodriguez F, Zarrabeitia R, Perez-Molino A, Hebbel RP, Nguyen J, Bernabeu C, Botella LM. 2005. Blood outgrowth endothelial cells from hereditary haemorrhagic telangiectasia patients reveal abnormalities compatible with vascular lesions. Cardiovasc. Res. 68:235-248. http://dx.doi.org/10.1016/j.cardiores.2005.06.009.
    • (2005) Cardiovasc. Res. , vol.68 , pp. 235-248
    • Fernandez-Lopez, A.1    Sanz-Rodriguez, F.2    Zarrabeitia, R.3    Perez-Molino, A.4    Hebbel, R.P.5    Nguyen, J.6    Bernabeu, C.7    Botella, L.M.8
  • 24
    • 70349260659 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells
    • Shao ES, Lin L, Yao Y, Bostrom KI. 2009. Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells. Blood 114:2197-2206. http://dx.doi.org/10.1182/blood-2009-01-199166.
    • (2009) Blood , vol.114 , pp. 2197-2206
    • Shao, E.S.1    Lin, L.2    Yao, Y.3    Bostrom, K.I.4
  • 25
    • 34248183465 scopus 로고    scopus 로고
    • Signaling by ALK5 mediates TGFbeta-induced ET-1 expression in endothelial cells: a role for migration and proliferation
    • Castañares C, Redondo-Horcajo M, Magan-Marchal N, ten Dijke P, Lamas S, Rodriguez-Pascual F. 2007. Signaling by ALK5 mediates TGFbeta-induced ET-1 expression in endothelial cells: a role for migration and proliferation. J. Cell Sci. 120:1256-1266. http://dx.doi.org/10.1242/jcs.03419.
    • (2007) J. Cell Sci. , vol.120 , pp. 1256-1266
    • Castañares, C.1    Redondo-Horcajo, M.2    Magan-Marchal, N.3    ten Dijke, P.4    Lamas, S.5    Rodriguez-Pascual, F.6
  • 27
    • 84863205849 scopus 로고    scopus 로고
    • NIH Image to ImageJ: 25 years of image analysis
    • Schneider CA, Rasband WS, Eliceiri KW. 2012. NIH Image to ImageJ: 25 years of image analysis. Nat. Methods 9:671-675. http://dx.doi.org/10.1038/nmeth.2089.
    • (2012) Nat. Methods , vol.9 , pp. 671-675
    • Schneider, C.A.1    Rasband, W.S.2    Eliceiri, K.W.3
  • 28
    • 78249258681 scopus 로고    scopus 로고
    • Bone morphogenic protein-9 stimulates endothelin-1 release from human pulmonary microvascular endothelial cells: a potential mechanism for elevated ET-1 levels in pulmonary arterial hypertension
    • Star GP, Giovinazzo M, Langleben D. 2010. Bone morphogenic protein-9 stimulates endothelin-1 release from human pulmonary microvascular endothelial cells: a potential mechanism for elevated ET-1 levels in pulmonary arterial hypertension. Microvasc. Res. 80:349-354. http://dx.doi.org/10.1016/j.mvr.2010.05.010.
    • (2010) Microvasc. Res. , vol.80 , pp. 349-354
    • Star, G.P.1    Giovinazzo, M.2    Langleben, D.3
  • 30
    • 0037204990 scopus 로고    scopus 로고
    • Signal transduction by the TGF-beta superfamily
    • Attisano L, Wrana JL. 2002. Signal transduction by the TGF-beta superfamily. Science 296:1646-1647. http://dx.doi.org/10.1126/science.1071809.
    • (2002) Science , vol.296 , pp. 1646-1647
    • Attisano, L.1    Wrana, J.L.2
  • 31
    • 80051471864 scopus 로고    scopus 로고
    • The specificities of small molecule inhibitors of the TGFss and BMP pathways
    • Vogt J, Traynor R, Sapkota GP. 2011. The specificities of small molecule inhibitors of the TGFss and BMP pathways. Cell. Signal. 23:1831-1842. http://dx.doi.org/10.1016/j.cellsig.2011.06.019.
    • (2011) Cell. Signal. , vol.23 , pp. 1831-1842
    • Vogt, J.1    Traynor, R.2    Sapkota, G.P.3
  • 32
    • 0037423374 scopus 로고    scopus 로고
    • Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses
    • Itoh S, Thorikay M, Kowanetz M, Moustakas A, Itoh F, Heldin CH, ten Dijke P. 2003. Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses. J. Biol. Chem. 278:3751-3761. http://dx.doi.org/10.1074/jbc.M208258200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 3751-3761
    • Itoh, S.1    Thorikay, M.2    Kowanetz, M.3    Moustakas, A.4    Itoh, F.5    Heldin, C.H.6    ten Dijke, P.7
  • 35
    • 77649242925 scopus 로고    scopus 로고
    • Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis
    • Rai D, Kim SW, McKeller MR, Dahia PL, Aguiar RC. 2010. Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. Proc. Natl. Acad. Sci. U. S. A. 107:3111-3116. http://dx.doi.org/10.1073/pnas.0910667107.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 3111-3116
    • Rai, D.1    Kim, S.W.2    McKeller, M.R.3    Dahia, P.L.4    Aguiar, R.C.5
  • 36
    • 0034654497 scopus 로고    scopus 로고
    • Controlling TGF-beta signaling
    • Massagué J, Chen YG. 2000. Controlling TGF-beta signaling. Genes Dev. 14:627-644. http://dx.doi.org/10.1101/gad.14.6.627.
    • (2000) Genes Dev. , vol.14 , pp. 627-644
    • Massagué, J.1    Chen, Y.G.2
  • 37
    • 79954606150 scopus 로고    scopus 로고
    • TGF-beta and restenosis revisited: a Smad link
    • Suwanabol PA, Kent KC, Liu B. 2011. TGF-beta and restenosis revisited: a Smad link. J. Surg. Res. 167:287-297. http://dx.doi.org/10.1016/j.jss.2010.12.020.
    • (2011) J. Surg. Res. , vol.167 , pp. 287-297
    • Suwanabol, P.A.1    Kent, K.C.2    Liu, B.3
  • 38
    • 3042588244 scopus 로고    scopus 로고
    • Expression of TGFbeta1 and beta3 but not apoptosis factors relates to flow-induced aortic enlargement
    • Xu C, Lee S, Shu C, Masuda H, Zarins CK. 2002. Expression of TGFbeta1 and beta3 but not apoptosis factors relates to flow-induced aortic enlargement. BMC Cardiovasc. Disord. 2:11. http://dx.doi.org/10.1186/1471-2261-2-11.
    • (2002) BMC Cardiovasc. Disord. , vol.2 , pp. 11
    • Xu, C.1    Lee, S.2    Shu, C.3    Masuda, H.4    Zarins, C.K.5
  • 39
    • 0141428794 scopus 로고    scopus 로고
    • Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways
    • Goumans MJ, Lebrin F, Valdimarsdottir G. 2003. Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways. Trends Cardiovasc. Med. 13:301-307. http://dx.doi.org/10.1016/S1050-1738(03)00142-7.
    • (2003) Trends Cardiovasc. Med. , vol.13 , pp. 301-307
    • Goumans, M.J.1    Lebrin, F.2    Valdimarsdottir, G.3
  • 40
    • 55849145475 scopus 로고    scopus 로고
    • Transforming growth factor betainduced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth
    • Daly AC, Randall RA, Hill CS. 2008. Transforming growth factor betainduced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth. Mol. Cell. Biol. 28:6889-6902. http://dx.doi.org/10.1128/MCB.01192-08.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 6889-6902
    • Daly, A.C.1    Randall, R.A.2    Hill, C.S.3
  • 42
    • 70350558678 scopus 로고    scopus 로고
    • Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signaling
    • Lee NY, Haney JC, Sogani J, Blobe GC. 2009. Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signaling. FASEB J. 23:3712-3721. http://dx.doi.org/10.1096/fj.09-131607.
    • (2009) FASEB J. , vol.23 , pp. 3712-3721
    • Lee, N.Y.1    Haney, J.C.2    Sogani, J.3    Blobe, G.C.4
  • 43
    • 0037184935 scopus 로고    scopus 로고
    • Regulation of ALK-1 signaling by the nuclear receptor LXRbeta
    • Mo J, Fang SJ, Chen W, Blobe GC. 2002. Regulation of ALK-1 signaling by the nuclear receptor LXRbeta. J. Biol. Chem. 277:50788-50794. http://dx.doi.org/10.1074/jbc.M210376200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 50788-50794
    • Mo, J.1    Fang, S.J.2    Chen, W.3    Blobe, G.C.4
  • 44
    • 0029163495 scopus 로고
    • Hereditary hemorrhagic telangiectasia
    • Guttmacher AE, Marchuk DA, White RI, Jr. 1995. Hereditary hemorrhagic telangiectasia. N. Engl. J. Med. 333:918-924. http://dx.doi.org/10.1056/NEJM199510053331407.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 918-924
    • Guttmacher, A.E.1    Marchuk, D.A.2    White Jr., R.I.3
  • 45
    • 0015430984 scopus 로고
    • Hereditary hemorrhagic telangiectasia. An electron microscopic study
    • Hashimoto K, Pritzker MS. 1972. Hereditary hemorrhagic telangiectasia. An electron microscopic study. Oral Surg. Oral Med. Oral Pathol. 34:751-768. http://dx.doi.org/10.1016/0030-4220(72)90293-9.
    • (1972) Oral Surg. Oral Med. Oral Pathol. , vol.34 , pp. 751-768
    • Hashimoto, K.1    Pritzker, M.S.2
  • 46
    • 77950564432 scopus 로고    scopus 로고
    • MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro
    • Quintavalle M, Elia L, Condorelli G, Courtneidge SA. 2010. MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro. J. Cell Biol. 189:13-22. http://dx.doi.org/10.1083/jcb.200912096.
    • (2010) J. Cell Biol. , vol.189 , pp. 13-22
    • Quintavalle, M.1    Elia, L.2    Condorelli, G.3    Courtneidge, S.A.4
  • 48
    • 58149264873 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of Smad proteins
    • Hill CS. 2009. Nucleocytoplasmic shuttling of Smad proteins. Cell Res. 19:36-46. http://dx.doi.org/10.1038/cr.2008.325.
    • (2009) Cell Res. , vol.19 , pp. 36-46
    • Hill, C.S.1
  • 50
    • 0141669167 scopus 로고    scopus 로고
    • Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA
    • Moreau V, Tatin F, Varon C, Genot E. 2003. Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA. Mol. Cell. Biol. 23:6809-6822. http://dx.doi.org/10.1128/MCB.23.19.6809-6822.2003.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 6809-6822
    • Moreau, V.1    Tatin, F.2    Varon, C.3    Genot, E.4
  • 51
    • 0038468558 scopus 로고    scopus 로고
    • Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta
    • Roberts AB, Russo A, Felici A, Flanders KC. 2003. Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta. Ann. N. Y. Acad. Sci. 995:1-10. http://dx.doi.org/10.1111/j.1749-6632.2003.tb03205.x.
    • (2003) Ann. N. Y. Acad. Sci. , vol.995 , pp. 1-10
    • Roberts, A.B.1    Russo, A.2    Felici, A.3    Flanders, K.C.4
  • 52
    • 0032934979 scopus 로고    scopus 로고
    • Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction
    • Datto MB, Frederick JP, Pan L, Borton AJ, Zhuang Y, Wang XF. 1999. Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol. Cell. Biol. 19:2495-2504.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2495-2504
    • Datto, M.B.1    Frederick, J.P.2    Pan, L.3    Borton, A.J.4    Zhuang, Y.5    Wang, X.F.6
  • 53
    • 0033534573 scopus 로고    scopus 로고
    • Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3
    • Yagi K, Goto D, Hamamoto T, Takenoshita S, Kato M, Miyazono K. 1999. Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3. J. Biol. Chem. 274:703-709.
    • (1999) J. Biol. Chem. , vol.274 , pp. 703-709
    • Yagi, K.1    Goto, D.2    Hamamoto, T.3    Takenoshita, S.4    Kato, M.5    Miyazono, K.6
  • 55
    • 83255186746 scopus 로고    scopus 로고
    • The Aarskog-Scott syndrome protein Fgd1 regulates podosome formation and extracellular matrix remodeling in transforming growth factor beta-stimulated aortic endothelial cells
    • Daubon T, Buccione R, Genot E. 2011. The Aarskog-Scott syndrome protein Fgd1 regulates podosome formation and extracellular matrix remodeling in transforming growth factor beta-stimulated aortic endothelial cells. Mol. Cell. Biol. 31:4430-4441. http://dx.doi.org/10.1128/MCB.05474-11.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 4430-4441
    • Daubon, T.1    Buccione, R.2    Genot, E.3
  • 56
    • 0033757655 scopus 로고    scopus 로고
    • Arteriovenous malformations in mice lacking activin receptor-like kinase-1
    • Urness LD, Sorenesen LK, Li DY. 2000. Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat. Genet. 26:328-331. http://dx.doi.org/10.1038/8163.4.
    • (2000) Nat. Genet. , vol.26 , pp. 328-331
    • Urness, L.D.1    Sorenesen, L.K.2    Li, D.Y.3


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