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Volumn 167, Issue 2, 2011, Pages 287-297

TGF-β and restenosis revisited: A smad link

Author keywords

angioplasty; intimal hyperplasia; restenosis; Smad; transforming growth factor beta (TGF )

Indexed keywords

ACETYLSALICYLIC ACID; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 79954606150     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.12.020     Document Type: Review
Times cited : (55)

References (101)
  • 1
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • J. Massague The transforming growth factor-β family Annu Rev Cell Biol 6 1990 597
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 597
    • Massague, J.1
  • 2
    • 0024314285 scopus 로고
    • Endothelial cell behavior after denudation injury is modulated by transforming growth factor-β1 and fibronectin
    • J.A. Madri, M.A. Reidy, and O. Kocher Endothelial cell behavior after denudation injury is modulated by transforming growth factor-β1 and fibronectin Lab Invest 60 1989 755
    • (1989) Lab Invest , vol.60 , pp. 755
    • Madri, J.A.1    Reidy, M.A.2    Kocher, O.3
  • 3
    • 0026075910 scopus 로고
    • Production of transforming growth factor β 1 during repair of arterial injury
    • M.W. Majesky, V. Lindner, and D.R. Twardzik Production of transforming growth factor β 1 during repair of arterial injury J Clin Invest 88 1991 904
    • (1991) J Clin Invest , vol.88 , pp. 904
    • Majesky, M.W.1    Lindner, V.2    Twardzik, D.R.3
  • 4
    • 0026450848 scopus 로고
    • Expression of transforming growth factor-β 1 is increased in human vascular restenosis lesions
    • S. Nikol, J.M. Isner, and J.G. Pickering Expression of transforming growth factor-β 1 is increased in human vascular restenosis lesions J Clin Invest 90 1992 1582
    • (1992) J Clin Invest , vol.90 , pp. 1582
    • Nikol, S.1    Isner, J.M.2    Pickering, J.G.3
  • 5
    • 0033510472 scopus 로고    scopus 로고
    • Histologic evidence of foreign body granulation tissue and de novo lesions in patients with coronary stent restenosis
    • C. Yutani, H. Ishibashi-Ueda, and T. Suzuki Histologic evidence of foreign body granulation tissue and de novo lesions in patients with coronary stent restenosis Cardiology 92 1999 171
    • (1999) Cardiology , vol.92 , pp. 171
    • Yutani, C.1    Ishibashi-Ueda, H.2    Suzuki, T.3
  • 6
    • 0034745179 scopus 로고    scopus 로고
    • TGF-β is active, and correlates with activators of TGF-β, following porcine coronary angioplasty
    • J. Chamberlain, J. Gunn, and S.E. Francis TGF-β is active, and correlates with activators of TGF-β, following porcine coronary angioplasty Cardiovasc Res 50 2001 125
    • (2001) Cardiovasc Res , vol.50 , pp. 125
    • Chamberlain, J.1    Gunn, J.2    Francis, S.E.3
  • 7
    • 0027497117 scopus 로고
    • Direct transfer of transforming growth factor β 1 gene into arteries stimulates fibrocellular hyperplasia
    • E.G. Nabel, L. Shum, and V.J. Pompili Direct transfer of transforming growth factor β 1 gene into arteries stimulates fibrocellular hyperplasia Proc Natl Acad Sci U S A 90 1993 10759
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 10759
    • Nabel, E.G.1    Shum, L.2    Pompili, V.J.3
  • 8
    • 0028786781 scopus 로고
    • In vivo effect of TGF-β 1. Enhanced intimal thickening by administration of TGF-β 1 in rabbit arteries injured with a balloon catheter
    • T. Kanzaki, K. Tamura, and K. Takahashi In vivo effect of TGF-β 1. Enhanced intimal thickening by administration of TGF-β 1 in rabbit arteries injured with a balloon catheter Arterioscler Thromb Vasc Biol 15 1995 1951
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1951
    • Kanzaki, T.1    Tamura, K.2    Takahashi, K.3
  • 9
    • 33646125178 scopus 로고    scopus 로고
    • Transforming growth factor-β1 antisense treatment of rat vein grafts reduces the accumulation of collagen and increases the accumulation of h-caldesmon
    • R.A. Wolff, R.L. Malinowski, and N.S. Heaton Transforming growth factor-β1 antisense treatment of rat vein grafts reduces the accumulation of collagen and increases the accumulation of h-caldesmon J Vasc Surg 43 2006 1028
    • (2006) J Vasc Surg , vol.43 , pp. 1028
    • Wolff, R.A.1    Malinowski, R.L.2    Heaton, N.S.3
  • 10
    • 0344702865 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of transforming growth factor-β3, but not transforming growth factor-β1, inhibits constrictive remodeling and reduces luminal loss after coronary angioplasty
    • P.A. Kingston, S. Sinha, and C.E. Appleby Adenovirus-mediated gene transfer of transforming growth factor-β3, but not transforming growth factor-β1, inhibits constrictive remodeling and reduces luminal loss after coronary angioplasty Circulation 108 2003 2819
    • (2003) Circulation , vol.108 , pp. 2819
    • Kingston, P.A.1    Sinha, S.2    Appleby, C.E.3
  • 11
    • 0028230233 scopus 로고
    • Antibodies against transforming growth factor-β 1 suppress intimal hyperplasia in a rat model
    • Y.G. Wolf, L.M. Rasmussen, and E. Ruoslahti Antibodies against transforming growth factor-β 1 suppress intimal hyperplasia in a rat model J Clin Invest 93 1994 1172
    • (1994) J Clin Invest , vol.93 , pp. 1172
    • Wolf, Y.G.1    Rasmussen, L.M.2    Ruoslahti, E.3
  • 12
    • 0034641666 scopus 로고    scopus 로고
    • Ribozyme oligonucleotides against transforming growth factor-β inhibited neointimal formation after vascular injury in rat model: Potential application of ribozyme strategy to treat cardiovascular disease
    • K. Yamamoto, R. Morishita, and N. Tomita Ribozyme oligonucleotides against transforming growth factor-β inhibited neointimal formation after vascular injury in rat model: Potential application of ribozyme strategy to treat cardiovascular disease Circulation 102 2000 1308
    • (2000) Circulation , vol.102 , pp. 1308
    • Yamamoto, K.1    Morishita, R.2    Tomita, N.3
  • 13
    • 0033612364 scopus 로고    scopus 로고
    • Soluble transforming growth factor-β type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth
    • J.D. Smith, S.R. Bryant, and L.L. Couper Soluble transforming growth factor-β type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth Circ Res 84 1999 1212
    • (1999) Circ Res , vol.84 , pp. 1212
    • Smith, J.D.1    Bryant, S.R.2    Couper, L.L.3
  • 14
    • 0035923567 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of a secreted transforming growth factor-β type II receptor inhibits luminal loss and constrictive remodeling after coronary angioplasty and enhances adventitial collagen deposition
    • P.A. Kingston, S. Sinha, and A. David Adenovirus-mediated gene transfer of a secreted transforming growth factor-β type II receptor inhibits luminal loss and constrictive remodeling after coronary angioplasty and enhances adventitial collagen deposition Circulation 104 2001 2595
    • (2001) Circulation , vol.104 , pp. 2595
    • Kingston, P.A.1    Sinha, S.2    David, A.3
  • 15
    • 33644604858 scopus 로고    scopus 로고
    • Vascular-wall remodeling of 3 human bypass vessels: Organ culture and smooth muscle cell properties
    • A. Mekontso-Dessap, M. Kirsch, and C. Guignambert Vascular-wall remodeling of 3 human bypass vessels: Organ culture and smooth muscle cell properties J Thorac Cardiovasc Surg 131 2006 651
    • (2006) J Thorac Cardiovasc Surg , vol.131 , pp. 651
    • Mekontso-Dessap, A.1    Kirsch, M.2    Guignambert, C.3
  • 16
    • 0023276691 scopus 로고
    • Compensatory enlargement of human atherosclerotic coronary arteries
    • S. Glagov, E. Weisenberg, and C.K. Zarins Compensatory enlargement of human atherosclerotic coronary arteries N Engl J Med 316 1987 1371
    • (1987) N Engl J Med , vol.316 , pp. 1371
    • Glagov, S.1    Weisenberg, E.2    Zarins, C.K.3
  • 17
    • 0019509380 scopus 로고
    • Complicating factors in evaluating coronary artery atherosclerosis
    • M.G. Bond, M.R. Adams, and B.C. Bullock Complicating factors in evaluating coronary artery atherosclerosis Artery 9 1981 21
    • (1981) Artery , vol.9 , pp. 21
    • Bond, M.G.1    Adams, M.R.2    Bullock, B.C.3
  • 18
    • 0029836030 scopus 로고    scopus 로고
    • Transforming growth factor-β 1 expression and myofibroblast formation during arterial repair
    • Y. Shi, J.E. O'Brien Jr., and A. Fard Transforming growth factor-β 1 expression and myofibroblast formation during arterial repair Arterioscler Thromb Vasc Biol 16 1996 1298
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1298
    • Shi, Y.1    O'Brien Jr., J.E.2    Fard, A.3
  • 19
    • 13844253337 scopus 로고    scopus 로고
    • The role of transforming growth factor β1 in the vascular system
    • J. Ghosh, M.O. Murphy, and N. Turner The role of transforming growth factor β1 in the vascular system Cardiovasc Pathol 14 2005 28
    • (2005) Cardiovasc Pathol , vol.14 , pp. 28
    • Ghosh, J.1    Murphy, M.O.2    Turner, N.3
  • 20
    • 0035726137 scopus 로고    scopus 로고
    • Biochemical assessment of myocardial fibrosis in hypertensive heart disease
    • B. Lopez, A. Gonzalez, and N. Varo Biochemical assessment of myocardial fibrosis in hypertensive heart disease Hypertension 38 2001 1222
    • (2001) Hypertension , vol.38 , pp. 1222
    • Lopez, B.1    Gonzalez, A.2    Varo, N.3
  • 21
    • 34250695906 scopus 로고    scopus 로고
    • Multiple transforming growth factor-β isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart
    • M.E. Mercado-Pimentel, and R.B. Runyan Multiple transforming growth factor-β isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart Cells Tissues Organs 185 2007 146
    • (2007) Cells Tissues Organs , vol.185 , pp. 146
    • Mercado-Pimentel, M.E.1    Runyan, R.B.2
  • 22
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-β family signalling
    • R. Derynck, and Y.E. Zhang Smad-dependent and Smad-independent pathways in TGF-β family signalling Nature 425 2003 577
    • (2003) Nature , vol.425 , pp. 577
    • Derynck, R.1    Zhang, Y.E.2
  • 24
    • 0032918016 scopus 로고    scopus 로고
    • Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-β1 in human prostate cancer cell lines
    • I. Sehgal, and T.C. Thompson Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-β1 in human prostate cancer cell lines Mol Biol Cell 10 1999 407
    • (1999) Mol Biol Cell , vol.10 , pp. 407
    • Sehgal, I.1    Thompson, T.C.2
  • 25
    • 33745947969 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 activation of transforming growth factor-β1 (TGF-β1) and TGF-β1-type II receptor signaling within the aged arterial wall
    • M. Wang, D. Zhao, and G. Spinetti Matrix metalloproteinase 2 activation of transforming growth factor-β1 (TGF-β1) and TGF-β1-type II receptor signaling within the aged arterial wall Arterioscler Thromb Vasc Biol 26 2006 1503
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1503
    • Wang, M.1    Zhao, D.2    Spinetti, G.3
  • 26
    • 58149230979 scopus 로고    scopus 로고
    • TGF-β signaling in vascular biology and dysfunction
    • M.J. Goumans, Z. Liu, and P. ten Dijke TGF-β signaling in vascular biology and dysfunction Cell Res 19 2009 116
    • (2009) Cell Res , vol.19 , pp. 116
    • Goumans, M.J.1    Liu, Z.2    Ten Dijke, P.3
  • 27
    • 0025989562 scopus 로고
    • Expression cloning and characterization of the TGF-β type III receptor
    • X.F. Wang, H.Y. Lin, and E. Ng-Eaton Expression cloning and characterization of the TGF-β type III receptor Cell 67 1991 797
    • (1991) Cell , vol.67 , pp. 797
    • Wang, X.F.1    Lin, H.Y.2    Ng-Eaton, E.3
  • 28
    • 12944273545 scopus 로고    scopus 로고
    • Activin receptor-like kinase 1 modulates transforming growth factor-β 1 signaling in the regulation of angiogenesis
    • S.P. Oh, T. Seki, and K.A. Goss Activin receptor-like kinase 1 modulates transforming growth factor-β 1 signaling in the regulation of angiogenesis Proc Natl Acad Sci U S A 97 2000 2626
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2626
    • Oh, S.P.1    Seki, T.2    Goss, K.A.3
  • 29
    • 30944436695 scopus 로고    scopus 로고
    • Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development
    • T. Seki, K.H. Hong, and S.P. Oh Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development Lab Invest 86 2006 116
    • (2006) Lab Invest , vol.86 , pp. 116
    • Seki, T.1    Hong, K.H.2    Oh, S.P.3
  • 30
    • 68549123472 scopus 로고    scopus 로고
    • New regulatory mechanisms of TGF-β receptor function
    • J.S. Kang, C. Liu, and R. Derynck New regulatory mechanisms of TGF-β receptor function Trends Cell Biol 19 2009 385
    • (2009) Trends Cell Biol , vol.19 , pp. 385
    • Kang, J.S.1    Liu, C.2    Derynck, R.3
  • 31
    • 0033625416 scopus 로고    scopus 로고
    • Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice
    • M.J. Goumans, and C. Mummery Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice Int J Dev Biol 44 2000 253
    • (2000) Int J Dev Biol , vol.44 , pp. 253
    • Goumans, M.J.1    Mummery, C.2
  • 32
    • 34548386720 scopus 로고    scopus 로고
    • TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA
    • M.K. Lee, C. Pardoux, and M.C. Hall TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA EMBO J 26 2007 3957
    • (2007) EMBO J , vol.26 , pp. 3957
    • Lee, M.K.1    Pardoux, C.2    Hall, M.C.3
  • 33
    • 34248584887 scopus 로고    scopus 로고
    • Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during breast cancer cell proliferation and invasion
    • A.J. Galliher, and W.P. Schiemann Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during breast cancer cell proliferation and invasion Cancer Res 67 2007 3752
    • (2007) Cancer Res , vol.67 , pp. 3752
    • Galliher, A.J.1    Schiemann, W.P.2
  • 34
    • 0034517389 scopus 로고    scopus 로고
    • Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation
    • P. Kavsak, R.K. Rasmussen, and C.G. Causing Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation Mol Cell 6 2000 1365
    • (2000) Mol Cell , vol.6 , pp. 1365
    • Kavsak, P.1    Rasmussen, R.K.2    Causing, C.G.3
  • 35
    • 17044414102 scopus 로고    scopus 로고
    • Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation
    • M. Yamashita, S.X. Ying, and G.M. Zhang Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation Cell 121 2005 101
    • (2005) Cell , vol.121 , pp. 101
    • Yamashita, M.1    Ying, S.X.2    Zhang, G.M.3
  • 36
    • 44649163272 scopus 로고    scopus 로고
    • The type i TGF-β receptor is covalently modified and regulated by sumoylation
    • J.S. Kang, E.F. Saunier, and R.J. Akhurst The type I TGF-β receptor is covalently modified and regulated by sumoylation Nat Cell Biol 10 2008 654
    • (2008) Nat Cell Biol , vol.10 , pp. 654
    • Kang, J.S.1    Saunier, E.F.2    Akhurst, R.J.3
  • 37
    • 0032213514 scopus 로고    scopus 로고
    • Transforming growth factor β type i receptor kinase mutant associated with metastatic breast cancer
    • T. Chen, D. Carter, and L. Garrigue-Antar Transforming growth factor β type I receptor kinase mutant associated with metastatic breast cancer Cancer Res 58 1998 4805
    • (1998) Cancer Res , vol.58 , pp. 4805
    • Chen, T.1    Carter, D.2    Garrigue-Antar, L.3
  • 38
    • 39049121312 scopus 로고    scopus 로고
    • How the Smads regulate transcription
    • S. Ross, and C.S. Hill How the Smads regulate transcription Int J Biochem Cell Biol 40 2008 383
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 383
    • Ross, S.1    Hill, C.S.2
  • 39
    • 0034654497 scopus 로고    scopus 로고
    • Controlling TGF-β signaling
    • J. Massague, and Y.G. Chen Controlling TGF-β signaling Genes Dev 14 2000 627
    • (2000) Genes Dev , vol.14 , pp. 627
    • Massague, J.1    Chen, Y.G.2
  • 40
    • 0033534573 scopus 로고    scopus 로고
    • Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3
    • K. Yagi, D. Goto, and T. Hamamoto Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3 J Biol Chem 274 1999 703
    • (1999) J Biol Chem , vol.274 , pp. 703
    • Yagi, K.1    Goto, D.2    Hamamoto, T.3
  • 41
    • 0032934979 scopus 로고    scopus 로고
    • Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction
    • M.B. Datto, J.P. Frederick, and L. Pan Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction Mol Cell Biol 19 1999 2495
    • (1999) Mol Cell Biol , vol.19 , pp. 2495
    • Datto, M.B.1    Frederick, J.P.2    Pan, L.3
  • 43
    • 33847716712 scopus 로고    scopus 로고
    • Negative regulation of TGF-β receptor/Smad signal transduction
    • S. Itoh, and P. ten Dijke Negative regulation of TGF-β receptor/Smad signal transduction Curr Opin Cell Biol 19 2007 176
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 176
    • Itoh, S.1    Ten Dijke, P.2
  • 44
    • 1642539976 scopus 로고    scopus 로고
    • GADD34-PP1c recruited by Smad7 dephosphorylates TGF-β type i receptor
    • W. Shi, C. Sun, and B. He GADD34-PP1c recruited by Smad7 dephosphorylates TGF-β type I receptor J Cell Biol 164 2004 291
    • (2004) J Cell Biol , vol.164 , pp. 291
    • Shi, W.1    Sun, C.2    He, B.3
  • 45
    • 33748531817 scopus 로고    scopus 로고
    • Ubiquitin-dependent regulation of TGF-β signaling in cancer
    • L. Izzi, and L. Attisano Ubiquitin-dependent regulation of TGF-β signaling in cancer Neoplasia 8 2006 677
    • (2006) Neoplasia , vol.8 , pp. 677
    • Izzi, L.1    Attisano, L.2
  • 46
    • 33745197796 scopus 로고    scopus 로고
    • FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type i receptor
    • T. Yamaguchi, A. Kurisaki, and N. Yamakawa FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor J Mol Endocrinol 36 2006 569
    • (2006) J Mol Endocrinol , vol.36 , pp. 569
    • Yamaguchi, T.1    Kurisaki, A.2    Yamakawa, N.3
  • 48
    • 0032428684 scopus 로고    scopus 로고
    • SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor
    • T. Tsukazaki, T.A. Chiang, and A.F. Davison SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor Cell 95 1998 779
    • (1998) Cell , vol.95 , pp. 779
    • Tsukazaki, T.1    Chiang, T.A.2    Davison, A.F.3
  • 49
    • 0037598870 scopus 로고    scopus 로고
    • Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
    • G.M. Di Guglielmo, C. Le Roy, and A.F. Goodfellow Distinct endocytic pathways regulate TGF-β receptor signalling and turnover Nat Cell Biol 5 2003 410
    • (2003) Nat Cell Biol , vol.5 , pp. 410
    • Di Guglielmo, G.M.1    Le Roy, C.2    Goodfellow, A.F.3
  • 50
    • 38149054804 scopus 로고    scopus 로고
    • Axin and GSK3- control Smad3 protein stability and modulate TGF-signaling
    • X. Guo, A. Ramirez, and D.S. Waddell Axin and GSK3- control Smad3 protein stability and modulate TGF-signaling Genes Dev 22 2008 106
    • (2008) Genes Dev , vol.22 , pp. 106
    • Guo, X.1    Ramirez, A.2    Waddell, D.S.3
  • 51
    • 33749487743 scopus 로고    scopus 로고
    • The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH
    • M.E. Maurer, and J.A. Cooper The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH J Cell Sci 119 2006 4235
    • (2006) J Cell Sci , vol.119 , pp. 4235
    • Maurer, M.E.1    Cooper, J.A.2
  • 52
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGF-β/Smad signaling system
    • J. Massague, and D. Wotton Transcriptional control by the TGF-β/Smad signaling system EMBO J 19 2000 1745
    • (2000) EMBO J , vol.19 , pp. 1745
    • Massague, J.1    Wotton, D.2
  • 53
    • 0033524943 scopus 로고    scopus 로고
    • Crystal structure of the cytoplasmic domain of the type i TGF-β receptor in complex with FKBP12
    • M. Huse, Y.G. Chen, and J. Massague Crystal structure of the cytoplasmic domain of the type I TGF-β receptor in complex with FKBP12 Cell 96 1999 425
    • (1999) Cell , vol.96 , pp. 425
    • Huse, M.1    Chen, Y.G.2    Massague, J.3
  • 54
    • 0033619255 scopus 로고    scopus 로고
    • Silencing of TGF-β signalling by the pseudoreceptor BAMBI
    • D. Onichtchouk, Y.G. Chen, and R. Dosch Silencing of TGF-β signalling by the pseudoreceptor BAMBI Nature 401 1999 480
    • (1999) Nature , vol.401 , pp. 480
    • Onichtchouk, D.1    Chen, Y.G.2    Dosch, R.3
  • 55
    • 0030961168 scopus 로고    scopus 로고
    • Smad4 and FAST-1 in the assembly of activin-responsive factor
    • X. Chen, E. Weisberg, and V. Fridmacher Smad4 and FAST-1 in the assembly of activin-responsive factor Nature 389 1997 85
    • (1997) Nature , vol.389 , pp. 85
    • Chen, X.1    Weisberg, E.2    Fridmacher, V.3
  • 56
    • 0032528236 scopus 로고    scopus 로고
    • The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-β-induced transcriptional activation
    • X.H. Feng, Y. Zhang, and R.Y. Wu The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-β-induced transcriptional activation Genes Dev 12 1998 2153
    • (1998) Genes Dev , vol.12 , pp. 2153
    • Feng, X.H.1    Zhang, Y.2    Wu, R.Y.3
  • 57
    • 0032527756 scopus 로고    scopus 로고
    • TGF-β-stimulated cooperation of smad proteins with the coactivators CBP/p300
    • R. Janknecht, N.J. Wells, and T. Hunter TGF-β-stimulated cooperation of smad proteins with the coactivators CBP/p300 Genes Dev 12 1998 2114
    • (1998) Genes Dev , vol.12 , pp. 2114
    • Janknecht, R.1    Wells, N.J.2    Hunter, T.3
  • 58
    • 0032483493 scopus 로고    scopus 로고
    • Physical and functional interaction of SMADs and p300/CBP
    • C. Pouponnot, L. Jayaraman, and J. Massague Physical and functional interaction of SMADs and p300/CBP J Biol Chem 273 1998 22865
    • (1998) J Biol Chem , vol.273 , pp. 22865
    • Pouponnot, C.1    Jayaraman, L.2    Massague, J.3
  • 59
    • 0031773264 scopus 로고    scopus 로고
    • TGF-β-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
    • X. Shen, P.P. Hu, and N.T. Liberati TGF-β-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein Mol Biol Cell 9 1998 3309
    • (1998) Mol Biol Cell , vol.9 , pp. 3309
    • Shen, X.1    Hu, P.P.2    Liberati, N.T.3
  • 60
    • 67650538040 scopus 로고    scopus 로고
    • Transforming growth factor-β promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells
    • F. Zhang, S. Tsai, and K. Kato Transforming growth factor-β promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells J Biol Chem 284 2009 17564
    • (2009) J Biol Chem , vol.284 , pp. 17564
    • Zhang, F.1    Tsai, S.2    Kato, K.3
  • 61
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-β signals
    • A. Moustakas, and C.H. Heldin Non-Smad TGF-β signals J Cell Sci 118 2005 3573
    • (2005) J Cell Sci , vol.118 , pp. 3573
    • Moustakas, A.1    Heldin, C.H.2
  • 62
    • 0030773834 scopus 로고    scopus 로고
    • Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
    • M. Kretzschmar, J. Doody, and J. Massague Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1 Nature 389 1997 618
    • (1997) Nature , vol.389 , pp. 618
    • Kretzschmar, M.1    Doody, J.2    Massague, J.3
  • 63
    • 0033605559 scopus 로고    scopus 로고
    • MEKK-1, a component of the stress (stress-activated protein kinase/c-Jun N-terminal kinase) pathway, can selectively activate Smad2-mediated transcriptional activation in endothelial cells
    • J.D. Brown, M.R. DiChiara, and K.R. Anderson MEKK-1, a component of the stress (stress-activated protein kinase/c-Jun N-terminal kinase) pathway, can selectively activate Smad2-mediated transcriptional activation in endothelial cells J Biol Chem 274 1999 8797
    • (1999) J Biol Chem , vol.274 , pp. 8797
    • Brown, J.D.1    Dichiara, M.R.2    Anderson, K.R.3
  • 64
    • 0033601179 scopus 로고    scopus 로고
    • Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription
    • M.E. Engel, M.A. McDonnell, and B.K. Law Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription J Biol Chem 274 1999 37413
    • (1999) J Biol Chem , vol.274 , pp. 37413
    • Engel, M.E.1    McDonnell, M.A.2    Law, B.K.3
  • 65
    • 0032572723 scopus 로고    scopus 로고
    • Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription
    • Y. Zhang, X.H. Feng, and R. Derynck Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription Nature 394 1998 909
    • (1998) Nature , vol.394 , pp. 909
    • Zhang, Y.1    Feng, X.H.2    Derynck, R.3
  • 66
    • 0032979988 scopus 로고    scopus 로고
    • Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor β
    • C. Wong, E.M. Rougier-Chapman, and J.P. Frederick Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor β Mol Cell Biol 19 1999 1821
    • (1999) Mol Cell Biol , vol.19 , pp. 1821
    • Wong, C.1    Rougier-Chapman, E.M.2    Frederick, J.P.3
  • 67
    • 24344460969 scopus 로고    scopus 로고
    • Involvement of furin-like proprotein convertases in the arterial response to injury
    • J.P. Sluijter, R.E. Verloop, and W.P. Pulskens Involvement of furin-like proprotein convertases in the arterial response to injury Cardiovasc Res 68 2005 136
    • (2005) Cardiovasc Res , vol.68 , pp. 136
    • Sluijter, J.P.1    Verloop, R.E.2    Pulskens, W.P.3
  • 68
    • 34147101606 scopus 로고    scopus 로고
    • Cthrc1 is a novel inhibitor of transforming growth factor-β signaling and neointimal lesion formation
    • R.J. LeClair, T. Durmus, and Q. Wang Cthrc1 is a novel inhibitor of transforming growth factor-β signaling and neointimal lesion formation Circ Res 100 2007 826
    • (2007) Circ Res , vol.100 , pp. 826
    • Leclair, R.J.1    Durmus, T.2    Wang, Q.3
  • 69
    • 70349095254 scopus 로고    scopus 로고
    • Chronic angiotensin-(1-7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits
    • W. Zeng, W. Chen, and X. Leng Chronic angiotensin-(1-7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits Biochem Biophys Res Commun 389 2009 138
    • (2009) Biochem Biophys Res Commun , vol.389 , pp. 138
    • Zeng, W.1    Chen, W.2    Leng, X.3
  • 70
    • 68049103323 scopus 로고    scopus 로고
    • TGF-β through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation
    • S. Tsai, S.T. Hollenbeck, and E.J. Ryer TGF-β through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation Am J Physiol Heart Circ Physiol 297 2009 H540
    • (2009) Am J Physiol Heart Circ Physiol , vol.297 , pp. 540
    • Tsai, S.1    Hollenbeck, S.T.2    Ryer, E.J.3
  • 71
    • 71549123218 scopus 로고    scopus 로고
    • Arterial gene transfer of the TGF-β signalling protein Smad3 induces adaptive remodelling following angioplasty: A role for CTGF
    • R. Kundi, S.T. Hollenbeck, and D. Yamanouchi Arterial gene transfer of the TGF-β signalling protein Smad3 induces adaptive remodelling following angioplasty: A role for CTGF Cardiovasc Res 84 2009 326
    • (2009) Cardiovasc Res , vol.84 , pp. 326
    • Kundi, R.1    Hollenbeck, S.T.2    Yamanouchi, D.3
  • 72
    • 65249093597 scopus 로고    scopus 로고
    • Characterization of primary and restenotic atherosclerotic plaque from the superficial femoral artery: Potential role of Smad3 in regulation of SMC proliferation
    • R.S. Edlin, S. Tsai, and D. Yamanouchi Characterization of primary and restenotic atherosclerotic plaque from the superficial femoral artery: Potential role of Smad3 in regulation of SMC proliferation J Vasc Surg 49 2009 1289
    • (2009) J Vasc Surg , vol.49 , pp. 1289
    • Edlin, R.S.1    Tsai, S.2    Yamanouchi, D.3
  • 73
    • 0038468558 scopus 로고    scopus 로고
    • Smad3: A key player in pathogenetic mechanisms dependent on TGF-β
    • A.B. Roberts, A. Russo, and A. Felici Smad3: A key player in pathogenetic mechanisms dependent on TGF-β Ann N Y Acad Sci 995 2003 1
    • (2003) Ann N y Acad Sci , vol.995 , pp. 1
    • Roberts, A.B.1    Russo, A.2    Felici, A.3
  • 74
    • 2142646426 scopus 로고    scopus 로고
    • Abraham DJ TGF-β signaling and the fibrotic response
    • A. Leask Abraham DJ TGF-β signaling and the fibrotic response FASEB J 18 2004 816
    • (2004) FASEB J , vol.18 , pp. 816
    • Leask, A.1
  • 75
    • 59949098048 scopus 로고    scopus 로고
    • Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-β1-induced CTGF expression in keloid fibroblasts
    • L.B. Lopes, E.J. Furnish, and P. Komalavilas Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-β1-induced CTGF expression in keloid fibroblasts J Invest Dermatol 129 2009 590
    • (2009) J Invest Dermatol , vol.129 , pp. 590
    • Lopes, L.B.1    Furnish, E.J.2    Komalavilas, P.3
  • 76
    • 34547116433 scopus 로고    scopus 로고
    • TGF-β- and CTGF-mediated fibroblast recruitment influences early outward vein graft remodeling
    • Z. Jiang, P. Yu, and M. Tao TGF-β- and CTGF-mediated fibroblast recruitment influences early outward vein graft remodeling Am J Physiol Heart Circ Physiol 293 2007 H482
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. 482
    • Jiang, Z.1    Yu, P.2    Tao, M.3
  • 77
    • 0037423374 scopus 로고    scopus 로고
    • Elucidation of Smad requirement in transforming growth factor-β type i receptor-induced responses
    • S. Itoh, M. Thorikay, and M. Kowanetz Elucidation of Smad requirement in transforming growth factor-β type I receptor-induced responses J Biol Chem 278 2003 3751
    • (2003) J Biol Chem , vol.278 , pp. 3751
    • Itoh, S.1    Thorikay, M.2    Kowanetz, M.3
  • 78
    • 18844387660 scopus 로고    scopus 로고
    • Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism
    • J. Rodriguez-Vita, E. Sanchez-Lopez, and V. Esteban Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism Circulation 111 2005 2509
    • (2005) Circulation , vol.111 , pp. 2509
    • Rodriguez-Vita, J.1    Sanchez-Lopez, E.2    Esteban, V.3
  • 79
    • 33646683786 scopus 로고    scopus 로고
    • PKCdelta is necessary for Smad3 expression and transforming growth factor β-induced fibronectin synthesis in vascular smooth muscle cells
    • E.J. Ryer, R.P. Hom, and K. Sakakibara PKCdelta is necessary for Smad3 expression and transforming growth factor β-induced fibronectin synthesis in vascular smooth muscle cells Arterioscler Thromb Vasc Biol 26 2006 780
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 780
    • Ryer, E.J.1    Hom, R.P.2    Sakakibara, K.3
  • 80
    • 21544479714 scopus 로고    scopus 로고
    • Smad7 gene transfer attenuates adventitial cell migration and vascular remodeling after balloon injury
    • C.M. Mallawaarachchi, P.L. Weissberg, and R.C. Siow Smad7 gene transfer attenuates adventitial cell migration and vascular remodeling after balloon injury Arterioscler Thromb Vasc Biol 25 2005 1383
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1383
    • Mallawaarachchi, C.M.1    Weissberg, P.L.2    Siow, R.C.3
  • 81
    • 20944432235 scopus 로고    scopus 로고
    • Targeted disruption of TGF-β-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury
    • K. Kobayashi, K. Yokote, and M. Fujimoto Targeted disruption of TGF-β-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury Circ Res 96 2005 904
    • (2005) Circ Res , vol.96 , pp. 904
    • Kobayashi, K.1    Yokote, K.2    Fujimoto, M.3
  • 82
    • 0036105149 scopus 로고    scopus 로고
    • Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis
    • M. Sata, A. Saiura, and A. Kunisato Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis Nat Med 8 2002 403
    • (2002) Nat Med , vol.8 , pp. 403
    • Sata, M.1    Saiura, A.2    Kunisato, A.3
  • 83
    • 59849108791 scopus 로고    scopus 로고
    • The role of progenitor cells in the development of intimal hyperplasia
    • S. Tsai, J. Butler, and S. Rafii The role of progenitor cells in the development of intimal hyperplasia J Vasc Surg 49 2009 502
    • (2009) J Vasc Surg , vol.49 , pp. 502
    • Tsai, S.1    Butler, J.2    Rafii, S.3
  • 84
    • 33644974307 scopus 로고    scopus 로고
    • RhoA modulates Smad signaling during transforming growth factor-β-induced smooth muscle differentiation
    • S. Chen, M. Crawford, and R.M. Day RhoA modulates Smad signaling during transforming growth factor-β-induced smooth muscle differentiation J Biol Chem 281 2006 1765
    • (2006) J Biol Chem , vol.281 , pp. 1765
    • Chen, S.1    Crawford, M.2    Day, R.M.3
  • 85
    • 77954253573 scopus 로고    scopus 로고
    • Transdifferentiation of bone marrow-derived endothelial progenitor cells into the smooth muscle cell lineage mediated by tansforming growth factor-β1
    • H. Imamura, T. Ohta, and K. Tsunetoshi Transdifferentiation of bone marrow-derived endothelial progenitor cells into the smooth muscle cell lineage mediated by tansforming growth factor-β1 Atherosclerosis 211 2010 114
    • (2010) Atherosclerosis , vol.211 , pp. 114
    • Imamura, H.1    Ohta, T.2    Tsunetoshi, K.3
  • 86
    • 12144289322 scopus 로고    scopus 로고
    • Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation
    • M.W. Feinberg, K. Shimizu, and M. Lebedeva Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation Circ Res 94 2004 601
    • (2004) Circ Res , vol.94 , pp. 601
    • Feinberg, M.W.1    Shimizu, K.2    Lebedeva, M.3
  • 87
    • 0028918825 scopus 로고
    • The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis
    • D.J. Grainger, P.R. Kemp, and J.C. Metcalfe The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis Nat Med 1 1995 74
    • (1995) Nat Med , vol.1 , pp. 74
    • Grainger, D.J.1    Kemp, P.R.2    Metcalfe, J.C.3
  • 88
    • 0036307946 scopus 로고    scopus 로고
    • Prognostic significance of plasma concentrations of transforming growth factor-β in patients with coronary artery disease
    • H. Tashiro, H. Shimokawa, and K. Sadamatu Prognostic significance of plasma concentrations of transforming growth factor-β in patients with coronary artery disease Coron Artery Dis 13 2002 139
    • (2002) Coron Artery Dis , vol.13 , pp. 139
    • Tashiro, H.1    Shimokawa, H.2    Sadamatu, K.3
  • 89
    • 0032849727 scopus 로고    scopus 로고
    • Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries
    • M. Erren, H. Reinecke, and R. Junker Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries Arterioscler Thromb Vasc Biol 19 1999 2355
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2355
    • Erren, M.1    Reinecke, H.2    Junker, R.3
  • 90
    • 0036007133 scopus 로고    scopus 로고
    • Low TGF-β1 serum levels are a risk factor for atherosclerosis disease in ESRD patients
    • S. Stefoni, G. Cianciolo, and G. Donati Low TGF-β1 serum levels are a risk factor for atherosclerosis disease in ESRD patients Kidney Int 61 2002 324
    • (2002) Kidney Int , vol.61 , pp. 324
    • Stefoni, S.1    Cianciolo, G.2    Donati, G.3
  • 91
    • 0035834818 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-β signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice
    • Z. Mallat, A. Gojova, and C. Marchiol-Fournigault Inhibition of transforming growth factor-β signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice Circ Res 89 2001 930
    • (2001) Circ Res , vol.89 , pp. 930
    • Mallat, Z.1    Gojova, A.2    Marchiol-Fournigault, C.3
  • 92
    • 0036078307 scopus 로고    scopus 로고
    • Transforming growth factor-β mediates balance between inflammation and fibrosis during plaque progression
    • E. Lutgens, M. Gijbels, and M. Smook Transforming growth factor-β mediates balance between inflammation and fibrosis during plaque progression Arterioscler Thromb Vasc Biol 22 2002 975
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 975
    • Lutgens, E.1    Gijbels, M.2    Smook, M.3
  • 93
    • 66349135076 scopus 로고    scopus 로고
    • The TGF-β paradox in human cancer: An update
    • M. Tian, and W.P. Schiemann The TGF-β paradox in human cancer: An update Future Oncol 5 2009 259
    • (2009) Future Oncol , vol.5 , pp. 259
    • Tian, M.1    Schiemann, W.P.2
  • 94
    • 77954557286 scopus 로고    scopus 로고
    • TGF-β and cancer metastasis: An inflammation link
    • L. Yang TGF-β and cancer metastasis: An inflammation link Cancer Metastasis Rev 29 2010 263
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 263
    • Yang, L.1
  • 95
    • 10144243313 scopus 로고    scopus 로고
    • Elevated plasma levels of transforming growth factor-β 1 in NIDDM
    • A. Pfeiffer, K. Middelberg-Bisping, and C. Drewes Elevated plasma levels of transforming growth factor-β 1 in NIDDM Diabetes Care 19 1996 1113
    • (1996) Diabetes Care , vol.19 , pp. 1113
    • Pfeiffer, A.1    Middelberg-Bisping, K.2    Drewes, C.3
  • 96
    • 70349656625 scopus 로고    scopus 로고
    • Transforming growth factor-β1 and incident type 2 diabetes: Results from the MONICA/KORA case-cohort study, 1984-2002
    • C. Herder, A. Zierer, and W. Koenig Transforming growth factor-β1 and incident type 2 diabetes: Results from the MONICA/KORA case-cohort study, 1984-2002 Diabetes Care 32 2009 1921
    • (2009) Diabetes Care , vol.32 , pp. 1921
    • Herder, C.1    Zierer, A.2    Koenig, W.3
  • 97
    • 0030512150 scopus 로고    scopus 로고
    • Transforming growth factor β in diabetic nephropathy
    • W.A. Border, T. Yamamoto, and N.A. Noble Transforming growth factor β in diabetic nephropathy Diabetes Metab Rev 12 1996 309
    • (1996) Diabetes Metab Rev , vol.12 , pp. 309
    • Border, W.A.1    Yamamoto, T.2    Noble, N.A.3
  • 98
    • 0034608937 scopus 로고    scopus 로고
    • Transforming growth factor β contributes to progressive diabetic nephropathy
    • W.B. Reeves, and T.E. Andreoli Transforming growth factor β contributes to progressive diabetic nephropathy Proc Natl Acad Sci U S A 97 2000 7667
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7667
    • Reeves, W.B.1    Andreoli, T.E.2
  • 99
    • 2442683897 scopus 로고    scopus 로고
    • Cigarette smoke concentrate increases 8-epi-PGF2alpha and TGF-β1 secretion in rat mesangial cells
    • C. Mur, J. Claria, and S. Rodela Cigarette smoke concentrate increases 8-epi-PGF2alpha and TGF-β1 secretion in rat mesangial cells Life Sci 75 2004 611
    • (2004) Life Sci , vol.75 , pp. 611
    • Mur, C.1    Claria, J.2    Rodela, S.3
  • 100
    • 13844280837 scopus 로고    scopus 로고
    • The G/C915 polymorphism of transforming growth factor β1 is associated with human longevity: A study in Italian centenarians
    • G. Carrieri, E. Marzi, and F. Olivieri The G/C915 polymorphism of transforming growth factor β1 is associated with human longevity: A study in Italian centenarians Aging Cell 3 2004 443
    • (2004) Aging Cell , vol.3 , pp. 443
    • Carrieri, G.1    Marzi, E.2    Olivieri, F.3
  • 101
    • 78651391823 scopus 로고    scopus 로고
    • Transforming growth factor β and soluble endoglin in the healthy senior and in Alzheimer ' s disease patients
    • B. Juraskova, C. Andrys, and I. Holmerova Transforming growth factor β and soluble endoglin in the healthy senior and in Alzheimer ' s disease patients J Nutr Health Aging 14 2010 758
    • (2010) J Nutr Health Aging , vol.14 , pp. 758
    • Juraskova, B.1    Andrys, C.2    Holmerova, I.3


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