메뉴 건너뛰기




Volumn 21, Issue 12, 2014, Pages 3882-3890

Epithelial to Mesenchymal Transition is Associated with Shorter Disease-Free Survival in Hepatocellular Carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; INTERLEUKIN 6; MESSENGER RNA; SORAFENIB; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UVOMORULIN; VIMENTIN; IL6 PROTEIN, HUMAN; NUCLEAR PROTEIN; TUMOR MARKER; TWIST1 PROTEIN, HUMAN;

EID: 84918828466     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-014-3779-2     Document Type: Article
Times cited : (62)

References (39)
  • 2
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • PID: 12189386, COI: 1:CAS:528:DC%2BD38Xksl2ltr8%3D
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer. 2002;2(6):442–54.
    • (2002) Nat Rev Cancer. , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 3
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial–mesenchymal transition
    • PID: 19487818, COI: 1:CAS:528:DC%2BD1MXntVCjtr0%3D
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009;119(6):1420–8.
    • (2009) J Clin Invest. , vol.119 , Issue.6 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 4
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • PID: 18485877, COI: 1:CAS:528:DC%2BD1cXmsVOru7w%3D
    • Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008;133(4):704–15.
    • (2008) Cell. , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 5
    • 33947192053 scopus 로고    scopus 로고
    • Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
    • PID: 17332325, COI: 1:CAS:528:DC%2BD2sXit12qurY%3D
    • Cheng GZ, Chan J, Wang Q, Zhang W, Sun CD, Wang LH. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res. 2007;67(5):1979–87.
    • (2007) Cancer Res. , vol.67 , Issue.5 , pp. 1979-1987
    • Cheng, G.Z.1    Chan, J.2    Wang, Q.3    Zhang, W.4    Sun, C.D.5    Wang, L.H.6
  • 6
    • 42049116522 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells
    • PID: 18381447, COI: 1:CAS:528:DC%2BD1cXktV2jsrc%3D
    • Fuchs BC, Fujii T, Dorfman JD, et al. Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells. Cancer Res. 2008;68(7):2391–9.
    • (2008) Cancer Res. , vol.68 , Issue.7 , pp. 2391-2399
    • Fuchs, B.C.1    Fujii, T.2    Dorfman, J.D.3
  • 7
    • 67650999217 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer
    • PID: 19584296, COI: 1:CAS:528:DC%2BD1MXosV2msb4%3D
    • Arumugam T, Ramachandran V, Fournier KF, et al. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Res. 2009;69(14):5820–8.
    • (2009) Cancer Res. , vol.69 , Issue.14 , pp. 5820-5828
    • Arumugam, T.1    Ramachandran, V.2    Fournier, K.F.3
  • 8
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • PID: 10655586, COI: 1:CAS:528:DC%2BD3cXhtVyltLw%3D
    • Cano A, Perez-Moreno MA, Rodrigo I, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol. 2000;2(2):76–83.
    • (2000) Nat Cell Biol. , vol.2 , Issue.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3
  • 9
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
    • PID: 18539112, COI: 1:CAS:528:DC%2BD1cXnsVCrs7g%3D
    • Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell. 2008;14(6):818–29.
    • (2008) Dev Cell. , vol.14 , Issue.6 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 10
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • PID: 15210113, COI: 1:CAS:528:DC%2BD2cXlsFWnu7w%3D
    • Yang J, Mani SA, Donaher JL, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell. 2004;117(7):927–39.
    • (2004) Cell. , vol.117 , Issue.7 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3
  • 11
    • 10644283018 scopus 로고    scopus 로고
    • In vitro hepatic differentiation of human mesenchymal stem cells
    • PID: 15562440, COI: 1:CAS:528:DC%2BD2MXhslahtw%3D%3D
    • Lee KD, Kuo TK, Whang-Peng J, et al. In vitro hepatic differentiation of human mesenchymal stem cells. Hepatology. 2004;40(6):1275–84.
    • (2004) Hepatology. , vol.40 , Issue.6 , pp. 1275-1284
    • Lee, K.D.1    Kuo, T.K.2    Whang-Peng, J.3
  • 12
    • 33846463379 scopus 로고    scopus 로고
    • Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
    • PID: 17187432, COI: 1:CAS:528:DC%2BD2sXht1arsb4%3D
    • Boyault S, Rickman DS, de Reynies A, et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology. 2007;45(1):42–52.
    • (2007) Hepatology. , vol.45 , Issue.1 , pp. 42-52
    • Boyault, S.1    Rickman, D.S.2    de Reynies, A.3
  • 13
    • 70349739285 scopus 로고    scopus 로고
    • Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
    • PID: 19723656, COI: 1:CAS:528:DC%2BD1MXhtFaku7vN
    • Hoshida Y, Nijman SM, Kobayashi M, et al. Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res. 2009;69(18):7385–92.
    • (2009) Cancer Res. , vol.69 , Issue.18 , pp. 7385-7392
    • Hoshida, Y.1    Nijman, S.M.2    Kobayashi, M.3
  • 14
    • 33749344520 scopus 로고    scopus 로고
    • Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
    • PID: 17000670, COI: 1:CAS:528:DC%2BD28XpvFShsLw%3D
    • Lee TK, Poon RT, Yuen AP, et al. Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res. 2006;12(18):5369–76.
    • (2006) Clin Cancer Res. , vol.12 , Issue.18 , pp. 5369-5376
    • Lee, T.K.1    Poon, R.T.2    Yuen, A.P.3
  • 15
    • 84863179793 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition predicts sensitivity to the dual IGF-1R/IR inhibitor OSI-906 in hepatocellular carcinoma cell lines
    • PID: 22161861, COI: 1:CAS:528:DC%2BC38XitFWks78%3D
    • Zhao H, Desai V, Wang J, Epstein DM, Miglarese M, Buck E. Epithelial-mesenchymal transition predicts sensitivity to the dual IGF-1R/IR inhibitor OSI-906 in hepatocellular carcinoma cell lines. Mol Cancer Ther. 2012;11(2):503–13.
    • (2012) Mol Cancer Ther. , vol.11 , Issue.2 , pp. 503-513
    • Zhao, H.1    Desai, V.2    Wang, J.3    Epstein, D.M.4    Miglarese, M.5    Buck, E.6
  • 16
    • 27744527762 scopus 로고    scopus 로고
    • Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma
    • PID: 16285938, COI: 1:CAS:528:DC%2BD2MXht12hu7fI
    • Giannelli G, Bergamini C, Fransvea E, Sgarra C, Antonaci S. Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma. Gastroenterology. 2005;129(5):1375–83.
    • (2005) Gastroenterology. , vol.129 , Issue.5 , pp. 1375-1383
    • Giannelli, G.1    Bergamini, C.2    Fransvea, E.3    Sgarra, C.4    Antonaci, S.5
  • 17
    • 33750559636 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial-mesenchymal transition
    • PID: 17047057, COI: 1:CAS:528:DC%2BD28XhtVyiurrJ
    • Lee TK, Man K, Poon RT, et al. Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial-mesenchymal transition. Cancer Res. 2006;66(20):9948–56.
    • (2006) Cancer Res. , vol.66 , Issue.20 , pp. 9948-9956
    • Lee, T.K.1    Man, K.2    Poon, R.T.3
  • 18
    • 80053212846 scopus 로고    scopus 로고
    • The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib
    • PID: 21885876, COI: 1:CAS:528:DC%2BC3MXhs1emt7nN
    • Yau T, Yao TJ, Chan P, et al. The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib. Oncologist. 2011;16(9):1270–9.
    • (2011) Oncologist. , vol.16 , Issue.9 , pp. 1270-1279
    • Yau, T.1    Yao, T.J.2    Chan, P.3
  • 19
    • 77957559384 scopus 로고    scopus 로고
    • Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma
    • PID: 20572033, COI: 1:CAS:528:DC%2BC3cXht1KnsLrF
    • Shao YY, Lin ZZ, Hsu C, Shen YC, Hsu CH, Cheng AL. Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma. Cancer. 2010;116(19):4590–6.
    • (2010) Cancer. , vol.116 , Issue.19 , pp. 4590-4596
    • Shao, Y.Y.1    Lin, Z.Z.2    Hsu, C.3    Shen, Y.C.4    Hsu, C.H.5    Cheng, A.L.6
  • 20
    • 84888294592 scopus 로고    scopus 로고
    • Genomic profiling of cell lines for personalized targeted therapy for hepatocellular carcinoma
    • PID: 23519950, COI: 1:CAS:528:DC%2BC3sXhvVGku7rE
    • Deshmukh M, Hoshida Y. Genomic profiling of cell lines for personalized targeted therapy for hepatocellular carcinoma. Hepatology. 2013;58(6):2207.
    • (2013) Hepatology. , vol.58 , Issue.6 , pp. 2207
    • Deshmukh, M.1    Hoshida, Y.2
  • 21
    • 30644468635 scopus 로고    scopus 로고
    • A twist for survival and cancer progression
    • PID: 16306876, COI: 1:CAS:528:DC%2BD28XisVGhsA%3D%3D
    • Puisieux A, Valsesia-Wittmann S, Ansieau S. A twist for survival and cancer progression. Br J Cancer. 2006;94(1):13–7.
    • (2006) Br J Cancer. , vol.94 , Issue.1 , pp. 13-17
    • Puisieux, A.1    Valsesia-Wittmann, S.2    Ansieau, S.3
  • 22
    • 84855428973 scopus 로고    scopus 로고
    • The correlation between TWIST, E-cadherin, and beta-catenin in human bladder cancer
    • PID: 22331730
    • Shen CH, Wu JD, Jou YC, et al. The correlation between TWIST, E-cadherin, and beta-catenin in human bladder cancer. J BUON. 2011;16(4):733–7.
    • (2011) J BUON. , vol.16 , Issue.4 , pp. 733-737
    • Shen, C.H.1    Wu, J.D.2    Jou, Y.C.3
  • 23
    • 74949116469 scopus 로고    scopus 로고
    • Significance of Twist expression and its association with E-cadherin in esophageal squamous cell carcinoma
    • PID: 20025748
    • Sasaki K, Natsugoe S, Ishigami S, et al. Significance of Twist expression and its association with E-cadherin in esophageal squamous cell carcinoma. J Exp Clin Cancer Res. 2009;28:158.
    • (2009) J Exp Clin Cancer Res. , vol.28 , pp. 158
    • Sasaki, K.1    Natsugoe, S.2    Ishigami, S.3
  • 24
    • 84863481932 scopus 로고    scopus 로고
    • Twist expression associated with the epithelial-mesenchymal transition in gastric cancer
    • PID: 22581441, COI: 1:CAS:528:DC%2BC38XptFCisb4%3D
    • Liu AN, Zhu ZH, Chang SJ, Hang XS. Twist expression associated with the epithelial-mesenchymal transition in gastric cancer. Mol Cell Biochem. 2012;367(1–2):195–203.
    • (2012) Mol Cell Biochem. , vol.367 , Issue.1-2 , pp. 195-203
    • Liu, A.N.1    Zhu, Z.H.2    Chang, S.J.3    Hang, X.S.4
  • 25
    • 68249162521 scopus 로고    scopus 로고
    • Twist expression promotes migration and invasion in hepatocellular carcinoma
    • PID: 19615090
    • Matsuo N, Shiraha H, Fujikawa T, et al. Twist expression promotes migration and invasion in hepatocellular carcinoma. BMC Cancer. 2009;9:240.
    • (2009) BMC Cancer. , vol.9 , pp. 240
    • Matsuo, N.1    Shiraha, H.2    Fujikawa, T.3
  • 26
    • 72949120827 scopus 로고    scopus 로고
    • Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma
    • PID: 19821482, COI: 1:CAS:528:DC%2BD1MXhsV2js7zN
    • Yang MH, Chen CL, Chau GY, et al. Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma. Hepatology. 2009;50(5):1464–74.
    • (2009) Hepatology. , vol.50 , Issue.5 , pp. 1464-1474
    • Yang, M.H.1    Chen, C.L.2    Chau, G.Y.3
  • 27
    • 80054720186 scopus 로고    scopus 로고
    • Expression of E-cadherin, N-cadherin and snail and their correlation with clinicopathological variants: an immunohistochemical study of 132 invasive ductal breast carcinomas in Egypt
    • PID: 22012049
    • ElMoneim HM, Zaghloul NM. Expression of E-cadherin, N-cadherin and snail and their correlation with clinicopathological variants: an immunohistochemical study of 132 invasive ductal breast carcinomas in Egypt. Clinics. 2011;66(10):1765–71.
    • (2011) Clinics. , vol.66 , Issue.10 , pp. 1765-1771
    • ElMoneim, H.M.1    Zaghloul, N.M.2
  • 28
    • 84868151188 scopus 로고    scopus 로고
    • The role of Snail in prostate cancer
    • PID: 23076049
    • Smith BN, Odero-Marah VA. The role of Snail in prostate cancer. Cell Adh Migr. 2012;6(5):433–41.
    • (2012) Cell Adh Migr. , vol.6 , Issue.5 , pp. 433-441
    • Smith, B.N.1    Odero-Marah, V.A.2
  • 29
    • 15544362735 scopus 로고    scopus 로고
    • K A, Bapat SA. Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level
    • PID: 15790452, COI: 1:CAS:528:DC%2BD2MXis1Grsb4%3D
    • Kurrey NK, K A, Bapat SA. Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level. Gynecol Oncol. 2005;97(1):155–65.
    • (2005) Gynecol Oncol. , vol.97 , Issue.1 , pp. 155-165
    • Kurrey, N.K.1
  • 30
    • 77956441256 scopus 로고    scopus 로고
    • SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo
    • PID: 20576520, COI: 1:CAS:528:DC%2BC3cXhtFGhur7K
    • Nishioka R, Itoh S, Gui T, et al. SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo. Exp Mol Pathol. 2010;89(2):149–57.
    • (2010) Exp Mol Pathol. , vol.89 , Issue.2 , pp. 149-157
    • Nishioka, R.1    Itoh, S.2    Gui, T.3
  • 31
    • 38849106118 scopus 로고    scopus 로고
    • Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma
    • PID: 17962206, COI: 1:STN:280:DC%2BD1c%2Fotlemuw%3D%3D
    • Porta C, De Amici M, Quaglini S, et al. Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma. Ann Oncol. 2008;19(2):353–8.
    • (2008) Ann Oncol. , vol.19 , Issue.2 , pp. 353-358
    • Porta, C.1    De Amici, M.2    Quaglini, S.3
  • 32
    • 46749146538 scopus 로고    scopus 로고
    • Hepatocellular carcinoma development requires hepatic stem cells with altered transforming growth factor and interleukin-6 signaling
    • PID: 18508299
    • Shackel NA, McCaughan GW, Warner FJ. Hepatocellular carcinoma development requires hepatic stem cells with altered transforming growth factor and interleukin-6 signaling. Hepatology. 2008;47(6):2134–6.
    • (2008) Hepatology. , vol.47 , Issue.6 , pp. 2134-2136
    • Shackel, N.A.1    McCaughan, G.W.2    Warner, F.J.3
  • 33
    • 65649111667 scopus 로고    scopus 로고
    • High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B
    • PID: 19267406, COI: 1:CAS:528:DC%2BD1MXltlCgtb0%3D
    • Wong VW, Yu J, Cheng AS, et al. High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B. Int J Cancer. 2009;124(12):2766–70.
    • (2009) Int J Cancer. , vol.124 , Issue.12 , pp. 2766-2770
    • Wong, V.W.1    Yu, J.2    Cheng, A.S.3
  • 34
    • 36849039660 scopus 로고    scopus 로고
    • IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
    • PID: 18060036, COI: 1:CAS:528:DC%2BD2sXhsValsLzK
    • Sansone P, Storci G, Tavolari S, et al. IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland. J Clin Invest. 2007;117(12):3988–4002.
    • (2007) J Clin Invest. , vol.117 , Issue.12 , pp. 3988-4002
    • Sansone, P.1    Storci, G.2    Tavolari, S.3
  • 35
    • 35948995750 scopus 로고    scopus 로고
    • Interleukin-6 is a potent growth factor for ER-alpha-positive human breast cancer
    • PID: 17586727, COI: 1:CAS:528:DC%2BD2sXht12jtr7K
    • Sasser AK, Sullivan NJ, Studebaker AW, Hendey LF, Axel AE, Hall BM. Interleukin-6 is a potent growth factor for ER-alpha-positive human breast cancer. FASEB J. 2007;21(13):3763–70.
    • (2007) FASEB J. , vol.21 , Issue.13 , pp. 3763-3770
    • Sasser, A.K.1    Sullivan, N.J.2    Studebaker, A.W.3    Hendey, L.F.4    Axel, A.E.5    Hall, B.M.6
  • 36
    • 55349104462 scopus 로고    scopus 로고
    • Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner
    • PID: 18974155, COI: 1:CAS:528:DC%2BD1cXhtlSkur3E
    • Studebaker AW, Storci G, Werbeck JL, et al. Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner. Cancer Res. 2008;68(21):9087–95.
    • (2008) Cancer Res. , vol.68 , Issue.21 , pp. 9087-9095
    • Studebaker, A.W.1    Storci, G.2    Werbeck, J.L.3
  • 37
    • 34447327216 scopus 로고    scopus 로고
    • Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
    • PID: 17615358, COI: 1:CAS:528:DC%2BD2sXnt1SjtLc%3D
    • Naugler WE, Sakurai T, Kim S, et al. Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science. 2007;317(5834):121–4.
    • (2007) Science. , vol.317 , Issue.5834 , pp. 121-124
    • Naugler, W.E.1    Sakurai, T.2    Kim, S.3
  • 38
    • 84885671431 scopus 로고    scopus 로고
    • Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling
    • PID: 24120137, COI: 1:CAS:528:DC%2BC3sXhs1SksLfI
    • He G, Dhar D, Nakagawa H, et al. Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. Cell. 2013;155(2):384–96.
    • (2013) Cell. , vol.155 , Issue.2 , pp. 384-396
    • He, G.1    Dhar, D.2    Nakagawa, H.3
  • 39
    • 69249221254 scopus 로고    scopus 로고
    • Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells
    • PID: 19581928, COI: 1:CAS:528:DC%2BD1MXotF2qsLo%3D
    • Sullivan NJ, Sasser AK, Axel AE, et al. Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells. Oncogene. 2009;28(33):2940–7.
    • (2009) Oncogene. , vol.28 , Issue.33 , pp. 2940-2947
    • Sullivan, N.J.1    Sasser, A.K.2    Axel, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.