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Volumn 16, Issue 9, 2011, Pages 1270-1279

The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib

Author keywords

Alpha fetoprotein; Hepatocellular carcinoma; Sorafenib; Surrogate

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ALPHA FETOPROTEIN; ANTIVIRUS AGENT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; HEPATITIS B SURFACE ANTIGEN; SORAFENIB;

EID: 80053212846     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2011-0105     Document Type: Article
Times cited : (94)

References (21)
  • 2
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocel-lular carcinoma
    • Llovet JM, Ricci S, Mazzaferro V et al. Sorafenib in advanced hepatocel-lular carcinoma. N Engl J Med 2008;359:378-390.
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3
  • 3
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
    • Cheng AL, Kang YK, Chen Z et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009;10:25-34.
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3
  • 4
    • 0003486931 scopus 로고
    • World Health Organization, WHO offset publication No. 48. Geneva: WHO
    • World Health Organization. WHO Handbook for Reporting Results of Cancer Treatment. WHO offset publication No. 48. Geneva: WHO, 1979.
    • (1979) WHO Handbook For Reporting Results of Cancer Treatment
  • 5
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000;92: 205-216.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 6
    • 68449100731 scopus 로고    scopus 로고
    • Serum alpha-fetoprotein response as a surrogate for clinical outcome in patients receiving systemic therapy for advanced hepatocellular carcinoma
    • Vora SR, Zheng H, Stadler ZK et al. Serum alpha-fetoprotein response as a surrogate for clinical outcome in patients receiving systemic therapy for advanced hepatocellular carcinoma. The Oncologist 2009;14:717-725.
    • (2009) The Oncologist , vol.14 , pp. 717-725
    • Vora, S.R.1    Zheng, H.2    Stadler, Z.K.3
  • 7
    • 79952108531 scopus 로고    scopus 로고
    • Advancement in HCC imaging: Diagnosis, staging and treatment efficacy assessments: Imaging diagnosis and staging of hepato-cellular carcinoma
    • Choi BI, Lee JM. Advancement in HCC imaging: diagnosis, staging and treatment efficacy assessments: imaging diagnosis and staging of hepato-cellular carcinoma. J Hepatobiliary Pancreat Sci 2010;17:369-373.
    • (2010) J Hepatobiliary Pancreat Sci , vol.17 , pp. 369-373
    • Choi, B.I.1    Lee, J.M.2
  • 8
    • 58749090909 scopus 로고    scopus 로고
    • New utility of an old marker: Serial alpha-fetoprotein measurement in predicting radiologic response and survival of patients with hepatocellular carcinoma undergoing systemic chemotherapy
    • Chan SL, Mo FK, Johnson PJ et al. New utility of an old marker: serial alpha-fetoprotein measurement in predicting radiologic response and survival of patients with hepatocellular carcinoma undergoing systemic chemotherapy. J Clin Oncol 2009;27:446-452.
    • (2009) J Clin Oncol , vol.27 , pp. 446-452
    • Chan, S.L.1    Mo, F.K.2    Johnson, P.J.3
  • 9
    • 33749017926 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
    • Abou-Alfa GK, Schwartz L, Ricci S et al. Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006;24: 4293-4300.
    • (2006) J Clin Oncol , vol.24 , pp. 4293-4300
    • Abou-Alfa, G.K.1    Schwartz, L.2    Ricci, S.3
  • 10
    • 44449085884 scopus 로고    scopus 로고
    • Design and endpoints of clinical trials in hepatocellular carcinoma
    • Llovet JM, Di Bisceglie AM, Bruix J et al. Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst 2008;100:698-711.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 698-711
    • Llovet, J.M.1    di Bisceglie, A.M.2    Bruix, J.3
  • 11
    • 23844534451 scopus 로고    scopus 로고
    • Alpha-fetoprotein response predicts survival benefits of thalidomide in advanced hepatocellular carcinoma
    • Chen LT, Liu TW, Chao Y et al. Alpha-fetoprotein response predicts survival benefits of thalidomide in advanced hepatocellular carcinoma. Aliment Pharmacol Ther 2005;22:217-226.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 217-226
    • Chen, L.T.1    Liu, T.W.2    Chao, Y.3
  • 12
    • 77957559384 scopus 로고    scopus 로고
    • Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma
    • Shao YY, Lin ZZ, Hsu C et al. Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma. Cancer 2010;116:4590-4596.
    • (2010) Cancer , vol.116 , pp. 4590-4596
    • Shao, Y.Y.1    Lin, Z.Z.2    Hsu, C.3
  • 13
    • 59449089100 scopus 로고    scopus 로고
    • Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: Presence of lung metastasis predicts poor response
    • Yau T, Chan P, Ng KK et al. Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response. Cancer 2009;115:428-436.
    • (2009) Cancer , vol.115 , pp. 428-436
    • Yau, T.1    Chan, P.2    Ng, K.K.3
  • 14
    • 0032879468 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: The BCLC staging classification
    • Llovet JM, Bru C, Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis 1999;19:329-338.
    • (1999) Semin Liver Dis , vol.19 , pp. 329-338
    • Llovet, J.M.1    Bru, C.2    Bruix, J.3
  • 15
    • 0003421882 scopus 로고    scopus 로고
    • Chapman & Hall/ CRC Texts in Statistical Science. Boca Raton, FL: CRC Press
    • Collett D. Modelling survival data in medical research. Chapman & Hall/ CRC Texts in Statistical Science. Boca Raton, FL: CRC Press, 2003.
    • (2003) Modelling Survival Data In Medical Research
    • Collett, D.1
  • 16
    • 84856804709 scopus 로고    scopus 로고
    • Cary, NC: SAS Institute Inc
    • The PHREG Procedure; Variable Selection Methods. Cary, NC: SAS Institute Inc. Available at http://support.sas.com/documentation/cdl/en/statug/63347/HTML/default/viewer.htm#statug_phreg_sect001.htm, accessed 2009.
    • (2009) The PHREG Procedure; Variable Selection Methods
  • 17
    • 77957888445 scopus 로고
    • Checking the Cox model with cumulative sums of martingale-based residuals
    • Lin DY, Wei LJ, Ying Z. Checking the Cox model with cumulative sums of martingale-based residuals. Biometrika 1993;80:557-572.
    • (1993) Biometrika , vol.80 , pp. 557-572
    • Lin, D.Y.1    Wei, L.J.2    Ying, Z.3
  • 18
    • 0034728356 scopus 로고    scopus 로고
    • What do we mean by validating a prognostic model?
    • Altman DG, Royston P. What do we mean by validating a prognostic model? Stat Med 2000;19:453-473.
    • (2000) Stat Med , vol.19 , pp. 453-473
    • Altman, D.G.1    Royston, P.2
  • 20
    • 73349142702 scopus 로고    scopus 로고
    • Alpha-Fetoprotein response after locore-gional therapy for hepatocellular carcinoma: Oncologic marker of radio-logic response, progression, and survival
    • Riaz A, Ryu RK, Kulik LM et al. Alpha-Fetoprotein response after locore-gional therapy for hepatocellular carcinoma: oncologic marker of radio-logic response, progression, and survival. J Clin Oncol 2009;27:5734- 5742.
    • (2009) J Clin Oncol , vol.27 , pp. 5734-5742
    • Riaz, A.1    Ryu, R.K.2    Kulik, L.M.3
  • 21
    • 77954397703 scopus 로고    scopus 로고
    • Fucosylated fraction of alpha-fetopro-tein as a predictor of prognosis in patients with hepatocellular carcinoma after curative treatment
    • Tamura Y, Igarashi M, Suda T et al. Fucosylated fraction of alpha-fetopro-tein as a predictor of prognosis in patients with hepatocellular carcinoma after curative treatment. Dig Dis Sci 2010;55:2095-2101.
    • (2010) Dig Dis Sci , vol.55 , pp. 2095-2101
    • Tamura, Y.1    Igarashi, M.2    Suda, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.