Melatonin promotes osteoblast differentiation and mineralization of MC3T3-E1 cells under hypoxic conditions through activation of PKD/p38 pathways

Journal of Pineal Research

Volumn 57, Issue 4, 2014, Pages 385-392

  Son, Jang Ho ^a   Cho, Yeong Cheol ^a   Sung, Iel Yong ^a   Kim, In Ryoung ^b   Park, Bong Soo ^b   Kim, Yong Deok ^b,c  

^a Ulsan University College of Medicine   (South Korea)

^b Pusan National University   (South Korea)

^c Pusan National University Hospital   (South Korea)

Author keywords

Bone metabolism; Hypoxia; Pineal gland; Signaling pathway

Indexed keywords

ALKALINE PHOSPHATASE; COL1 PROTEIN; MELATONIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; OCN PROTEIN; OSX PROTEIN; PRKD1 PROTEIN; UNCLASSIFIED DRUG; ANTIOXIDANT; PROTEIN KINASE C; PROTEIN KINASE D;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MINERALIZATION; CELL CULTURE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; HYPOXIA; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL HYPOXIA; CELL LINE; DRUG EFFECTS; METABOLISM; MOUSE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE; MAP KINASE SIGNALING SYSTEM; MELATONIN; MICE; OSTEOBLASTS; PROTEIN KINASE C; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84918822387     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12177     Document Type: Article

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