Fracture healing: The diamond concept

Injury

Volumn 38, Issue 4 SUPPL., 2007, Pages

  Giannoudis, Peter V ^a   Einhorn, Thomas A ^b   Marsh, David ^c  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^c ROYAL ORTHOPAEDIC HOSPITAL   (United Kingdom)

Author keywords

Bone restoration; Cells; Fracture healing; Growth factors; Mechanical stability; Scaffolds

Indexed keywords

BIOMATERIAL;

ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; FRACTURE FIXATION; FRACTURE HEALING; HUMAN; MECHANICS; MEDICAL PRACTICE; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; TISSUE ENGINEERING;

BIOMECHANICS; BONE MORPHOGENETIC PROTEINS; BONE TRANSPLANTATION; BONY CALLUS; EXTRACELLULAR MATRIX; FRACTURE HEALING; FRACTURES, BONE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESENCHYMAL STEM CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 38549116503     PISSN: 00201383     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-1383(08)70003-2     Document Type: Article

References (44)

1. Aaron R., Ciombor D., Wang S., and Simon B. Clinical biophysics: the promotion of skeletal repair by physical forces. Ann N Y Acad Sci 1068 (2006) 513-531
2. Augat P., Margevicius K., Simon J., et al. Local tissue properties in bone healing: influence of size and stability of the osteotomy gap. J Orthop Res 16 (1998) 475-481
3. Babis G., and Soucacos P. Bone scaffolds: the role of mechanical stability and instrumentation. Injury 36 Suppl 4 (2005) S38-S44
4. Bolander M. Regulation of fracture repair by growth factors. Proc Soc Exp Biol Med 200 (1992) 165-170
5. Brighton C., and Hunt R. Early histological and ultrastructural changes in medullary fracture callus. J Bone Joint Surg Am 73 (1991) 832-847
6. Carter D., Beaupre G., Giori N., and Helms J. Mechanobiology of skeletal regeneration. Clin Orthop Relat Res (1998) S41-S55
7. Chao E., and Inoue N. Biophysical stimulation of bone fracture repair, regeneration and remodelling. Eur Cell Mater 6 (2003) 72-84 discussion -5.
8. Connolly J. Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis. Clin Orthop Relat Res (1998) S257-S266
9. Connolly J. Injectable bone marrow preparations to stimulate osteogenic repair. Clin Orthop Relat Res (1995) 8-18
10. Dimitriou R., Tsiridis E., Carr I., et al. The role of inhibitory molecules in fracture healing. Injury 37 Suppl 1 (2006) S20-S29
11. Dinopoulos H., and Giannoudis P. Safety and efficacy of use of demineralised bone matrix in orthopaedic and trauma surgery. Expert Opin Drug Saf 5 (2006) 847-866
12. Einhorn T. The cell and molecular biology of fracture healing. Clin Orthop Relat Res (1998) S7-S21
13. Einhorn T. Clinical applications of recombinant human BMPs: early experience and future development. J Bone Joint Surg Am 85-A Suppl 3 (2003) 82-88
14. Einhorn T., Majeska R., Rush E., et al. The expression of cytokine activity by fracture callus. J Bone Miner Res 10 (1995) 1272-1281
15. Friedlaender G., Perry C., Cole J., et al. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Joint Surg Am 83-A Suppl 1 (2001) S151-S158
16. Giannoudis P., and Tzioupis C. Clinical applications of BMP-7: the UK perspective. Injury 36 Suppl 3 (2005) S47-S50
17. Gil-Albarova J., Salinas A., Bueno-Lozano A., et al. The in vivo behaviour of a sol-gel glass and a glass-ceramic during critical diaphyseal bone defects healing. Biomaterials 26 (2005) 4374-4382
18. Gould S., Rhee J., Tay B.-B., et al. Cellular contribution of bone graft to fusion. J Orthop Res 18 (2000) 920-927
19. Harwood P., and Giannoudis P. Application of bone morphogenetic proteins in orthopaedic practice: their efficacy and side effects. Expert Opin Drug Saf 4 (2005) 75-89
20. Higgins T., Dodds S., and Wolfe S. A biomechanical analysis of fixation of intra-articular distal radial fractures with calcium-phosphate bone cement. J Bone Joint Surg Am 84-A (2002) 1579-1586
21. Kain M., and Einhorn T. Recombinant human bone morphogenetic proteins in the treatment of fractures. Foot Ankle Clin 10 (2005) 639-650 viii.
22. Khan S., Tomin E., and Lane J. Clinical applications of bone graft substitutes. Orthop Clin North Am 31 (2000) 389-398
23. Lacroix D., and Prendergast P. A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading. J Biomech 35 (2002) 1163-1171
24. Lanyon L. Control of bone architecture by functional load bearing. J Bone Miner Res 7 Suppl 2 (1992) S369-S375
25. Leunig M., Hertel R., Siebenrock K., et al. The evolution of indirect reduction techniques for the treatment of fractures. Clin Orthop Relat Res 375 (2000) 7-14
26. Lieberman J., Daluiski A., Stevenson S., et al. The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. J Bone Joint Surg Am 81 (1999) 905-917
27. Lyritis G. The history of the walls of the Acropolis of Athens and the natural history of secondary fracture healing process. J Musculoskelet Neuronal Interact 1 (2000) 1-3
28. Matziolis G., Tuischer J., Kasper G., et al. Simulation of cell differentiation in fracture healing: mechanically loaded composite scaffolds in a novel bioreactor system. Tissue Eng 12 (2006) 201-208
29. McKibbin B. The biology of fracture healing in long bones. J Bone Joint Surg Br 60-B (1978) 150-162
30. Muller ME, Allgower M, Schneider R, Willenegger H. Manual of internal fixation. 1991.
31. Olsen B., Reginato A., and Wang W. Bone development. Annu Rev Cell Dev Biol 16 (2000) 191-220
32. Perren S. The concept of biological plating using the limited contact-dynamic compression plate (LC-DCP). Scientific background, design and application. Injury 22 Suppl 1 (1991) 1-41
33. Perren S. Physical and biological aspects of fracture healing with special reference to internal fixation. Clin Orthop Relat Res 138 (1979) 175-196
34. Perren S., and Rahn B. Biomechanics of fracture healing. Can J Surg 23 (1980) 228-232
35. Pountos I., and Giannoudis P. Biology of mesenchymal stem cells. Injury 36 Suppl 3 (2005) S8-S12
36. Sammarco V., and Chang L. Modern issues in bone graft substitutes and advances in bone tissue technology. Foot Ankle Clin 7 (2002) 19-41
37. Sporer S., and Paprosky W. Biologic fixation and bone ingrowth. Orthop Clin North Am 36 (2005) 105-111
38. Stylios G., Wan T., and Giannoudis P. Present status and future potential of enhancing bone healing using nanotechnology. Injury 38 Suppl 1 (2007) S63-S74
39. Tsiridis E., and Giannoudis P. Transcriptomics and proteomics: advancing the understanding of genetic basis of fracture healing. Injury 37 Suppl 1 (2006) S13-S19
40. Tsiridis E., Upadhyay N., and Giannoudis P. Molecular aspects of fracture healing: which are the important molecules?. Injury 38 Suppl 1 (2007) S11-S25
41. Tsiridis E., Upadhyay N., and Giannoudis P. Molecular aspects of fracture healing:Which are the important molecules?. Injury 38 Suppl 1 (2007) S11-S25
42. Vaccaro A. The role of the osteoconductive scaffold in synthetic bone graft. Orthopedics 25 (2002) s571-s578
43. Westerhuis R., van Bezooijen R., and Kloen P. Use of bone morphogenetic proteins in traumatology. Injury 36 (2005) 1405-1412
44. Wolff J. Das gesetz der transformation der knochen (1892), Verlag von Augsut Hirschwald, Berlin