Matrix tablets for sustained release of repaglinide: Preparation, pharmacokinetics and hypoglycemic activity in beagle dogs

International Journal of Pharmaceutics

Volumn 478, Issue 1, 2015, Pages 297-307

  He, Wei ^a   Wu, Mengmeng ^a   Huang, Shiqing ^b   Yin, Lifang ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Third People's Hospital of Chengdu   (China)

Author keywords

Hypoglycemic effect; In vitro in vivo correlation; Pharmacokinetics; Repaglinide; Sustained release tablets

Indexed keywords

AEROSIL; CITRIC ACID; GLUCOSE; MAGNESIUM STEARATE; OCTADECANOL; POLYMER; REPAGLINIDE; TARTARIC ACID; ANTIDIABETIC AGENT; CARBAMIC ACID DERIVATIVE; DELAYED RELEASE FORMULATION; GLUCOSE BLOOD LEVEL; PIPERIDINE DERIVATIVE; TABLET;

ANIMAL EXPERIMENT; ANTIDIABETIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM; DRUG HALF LIFE; DRUG SOLUBILITY; DUODENUM; EXPERIMENTAL DOG; GLUCOSE ASSAY; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; JEJUNUM; MALE; MATRIX TABLET; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MEDICATION COMPLIANCE; NONHUMAN; OSMOTIC PUMP; PLASMA CONCENTRATION-TIME CURVE; POROSITY; SMALL INTESTINE; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION; SUSTAINED RELEASE PREPARATION; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; VISCOSITY; WATER TRANSPORT; ANALYSIS; ANIMAL; BLOOD; CHEMISTRY; DELAYED RELEASE FORMULATION; DOG; DRUG RELEASE; PHARMACOKINETICS; PHARMACOLOGY; TABLET;

ANIMALS; BLOOD GLUCOSE; CARBAMATES; DELAYED-ACTION PREPARATIONS; DOGS; DRUG LIBERATION; HYPOGLYCEMIC AGENTS; PIPERIDINES; TABLETS;

EID: 84918808461     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.11.059     Document Type: Article

References (34)

1. A. Aguilar-de-Leyva, C. Cifuentes, A.R. Rajabi-Siahboomi, and I. Caraballo Study of the critical points and the role of the pores and viscosity in carbamazepine hydrophilic matrix tablets Eur. J. Pharm. Biopharm. 80 2012 136 142
2. S.I.F. Badawy, and M.A. Hussain Microenvironmental pH modulation in solid dosage forms J. Pharm. Sci. 96 2007 948 959
3. G. Corti, M. Cirri, F. Maestrelli, N. Mennini, and P. Mura Sustained-release matrix tablets of metformin hydrochloride in combination with triacetyl-β-cyclodextrin Eur. J. Pharm. Biopharm. 68 2008 303 309
4. G. De Berardis, A. Dttorre, G. Graziano, G. Lucisano, F. Pellegrini, S. Cammarota, A. Citarella, C.A. Germinario, V. Lepore, E. Menditto, A. Nicolosi, F. Vitullo, and A. Nicolucci The burden of hospitalization related to diabetes mellitus: a population-based study Nutr. Metab. Cardiovasc. Dis. 22 2013 605 612
5. R.A. DeFronzo Pharmacologic therapy for type 2 diabetes mellitus Ann. Intern. Med. 131 1999 281 303
6. K. Dvořáčková, P. Doležel, E. Mašková, J. Muselík, M. Kejdušová, and D. Vetchý The Effect of acid pH modifiers on the release characteristics of weakly basic drug from hydrophlilic-lipophilic matrices AAPS PharmSciTech 14 2013 1341 1348
7. C. Ferrero, D. Massuelle, D. Jeannerat, and E. Doelker Towards elucidation of the drug release mechanism from compressed hydrophilic matrices made of cellulose ethers. III. Critical use of thermodynamic parameters of activation for modeling the water penetration and drug release processes J. Control. Release 170 2013 175 182
8. T. Goncalves-Araujo, A.R. Rajabi-Siahboomi, and I. Caraballo Application of percolation theory in the study of an extended release verapamil hydrochloride formulation Int. J. Pharm. 361 2008 112 117
9. B.U. Killen, and O.I. Corrigan Effect of soluble filler on drug release from stearic acid based compacts Int. J. Pharm. 316 2006 47 51
10. C.K. Kramer, B. Zinman, J.L. Gross, L.H. Canani, T.C. Rodrigues, M.J. Azevedo, and R. Retnakaran Coronary artery calcium score prediction of all cause mortality and cardiovascular events in people with type 2 diabetes: systematic review and meta-analysis BMJ 346 2013 f1654
11. J.D. Lalau, M.L. Azzoug, F. Kajbaf, C. Briet, and R. Desailloud Metformin accumulation without hyperlactataemia and metformin-induced hyperlactataemia without metformin accumulation Diabetes Metab. 40 2014 220 223
12. F. Lotfipour, A. Nokhodchi, M. Saeedi, S. Norouzi-Sani, J. Sharbafi, and M.R. Siahi-Shadbad The effect of hydrophilic and lipophilic polymers and fillers on the release rate of atenolol from HPMC matrices Farmaco 59 2004 819 825
13. Y. Lu, S. Kim, and K. Park In vitro-in vivo correlation: perspectives on model development Int. J. Pharm. 418 2011 142 148
14. J.G. Lyons, D.M. Devine, J.E. Kennedy, L.M. Geever, P. O'sullivan, and C.L. Higginbotham The use of agar as a novel filler for monolithic matrices produced using hot melt extrusion Eur. J. Pharm. Biopharm. 64 2006 75 81
15. C. Maderuelo, A. Zarzuelo, and J.M. Lanao Critical factors in the release of drugs from sustained release hydrophilic matrices J. Control. Release 154 2011 2 19
16. T. Martinello, T.M. Kaneko, M.V. Velasco, M.E. Taqueda, and V.O. Consiglieri Optimization of poorly compactable drug tablets manufactured by direct compression using the mixture experimental design Int. J. Pharm. 322 2006 87 95
17. R.S. Obach, F. Lombardo, and N.J. Waters Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds Drug Metab. Dispos. 36 2008 1385 1405
18. C. Qin, W. He, C. Zhu, M. Wu, Z. Jin, Q. Zhang, G. Wang, and L. Yin Controlled release of metformin hydrochloride and repaglinide from sandwiched osmotic pump tablet Int. J. Pharm. 466 2014 276 285
19. T. Quinten, Y. Gonnissen, E. Adriaens, T.D. Beer, V. Cnudde, B. Masschaele, L. Van Hoorebeke, J. Siepmann, J.P. Remon, and C. Vervaet Development of injection moulded matrix tablets based on mixtures of ethylcellulose and low-substituted hydroxypropylcellulose Eur. J. Pharm. Sci. 37 2009 207 216
20. M.S. Reza, M.A. Quadir, and S.S. Haider Comparative evaluation of plastic, hydrophobic and hydrophilic polymers as matrices for controlled-release drug delivery J. Pharm. Pharm. Sci. 6 2003 282 291
21. L.J. Scott Repaglinide: a review of its use in type 2 diabetes mellitus Drugs 72 2012 249 272
22. S. Siepe, B. Lueckel, A. Kramer, A. Ries, and R. Gurny Strategies for the design of hydrophilic matrix tablets with controlled microenvironmental pH Int. J. Pharm. 316 2006 14 20
23. J. Siepmann, and N.A. Peppas Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC) Adv. Drug Deliv. Rev. 64 2012 163 174
24. E. Sjögren, B. Abrahamsson, P. Augustijns, D. Becker, M.B. Bolger, M. Brewster, J. Brouwers, T. Flanagan, M. Harwood, C. Heinen, R. Holm, H.-P. Juretschke, M. Kubbinga, A. Lindahl, V. Lukacova, U. Münster, S. Neuhoff, M.A. Nguyen, A.v. Peer, C. Reppas, A.R. Hodjegan, C. Tannergren, W. Weitschies, C. Wilson, P. Zane, H. Lennernäs, and P. Langguth In vivo methods for drug absorption-comparative physiologies model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects Eur. J. Pharm. Sci. 57 2014 99 151
25. P. Sriamornsak, N. Thirawong, and K. Korkerd Swelling: erosion and release behavior of alginate-based matrix tablets Eur. J. Pharm. Biopharm. 66 2007 435 450
26. P. Sriamornsak, J. Nunthanid, M. Luangtana-anan, Y. Weerapol, and S. Puttipipatkhachorn Alginate-based pellets prepared by extrusion/spheronization: effect of the amount and type of sodium alginate and calcium salts Eur. J. Pharm. Biopharm. 69 2008 274 284
27. M.V.S. Varma, A.M. Kaushal, and S. Garg Influence of micro-environmental pH on the gel layer behavior and release of a basic drug from various hydrophilic matrices J. Control. Release 103 2005 499 510
28. X. Wei, N. Sun, B. Wu, C. Yin, and W. Wu Sigmoidal release of indomethacin from pectin matrix tablets: effect of in situ crosslinking by calcium cations Int. J. Pharm. 318 2006 132 138
29. B. Wu, Z. Chen, X. Wei, N. Sun, Y. Lu, and W. Wu Biphasic release of indomethacin from HPMC/pectin/calcium matrix tablet: I. Characterization and mechanistic study Eur. J. Pharm. Biopharm. 67 2007 707 714
30. B. Wu, D. Deng, Y. Lu, and W. Wu Biphasic release of indomethacin from HPMC/pectin/calcium matrix tablet: II. Influencing variables, stability and pharmacokinetics in dogs Eur. J. Pharm. Biopharm. 69 2008 294 302
31. S.H. Yang, K.F. Dou, and W.J. Song Prevalence of diabetes among men and women in China New Engl. J. Med. 362 2010 2425 2426
32. L.F. Yin, S.J. Huang, C.L. Zhu, S.H. Zhang, Q. Zhang, X.J. Chen, and Q.W. Liu In vitro and in vivo studies on a novel solid dispersion of repaglinide using polyvinylpyrrolidone as the carrier Drug Dev. Ind. Pharm. 38 2012 1371 1380
33. X. Zhang, J. Qi, Y. Lu, W. He, X. Li, and W. Wu Biotinylated liposomes as potential carriers for the oral delivery of insulin Nanomedicine 10 2014 167 176
34. H. Zhu, X. Zhang, M.Z. Li, J. Xie, and X.L. Yang Prevalence of Type 2 diabetes and pre-diabetes among overweight or obese children in Tianjin China Diabet. Med. 30 2013 1457 1465